Direct Impact

Concepts for which Kenneth K Wang has direct influence:

endoscopic mucosal
ablation therapy
confocal microscopy
barrett esophagus
volumetric laser
erosive reflux
breath profiles

External impact

Concepts related to the work of other authors for which Kenneth K Wang has influence:

vagal-sparing esophagectomy
bile duct
methylated dna markers
prostate cancer
telomerase activity
accurate nonendoscopic
preclinical pharmacology

Prominent publications by Kenneth K Wang

KOL-Index: 61 BACKGROUND AND AIMS: Previous estimates of incidence of intestinal metaplasia (IM) recurrence after achieving complete remission of IM (CRIM) through endoscopic therapy of Barrett's esophagus (BE) have varied widely. We performed a systematic review and meta-analysis of studies to estimate an accurate recurrence risk after CRIM. METHODS: We performed a systematic search of multiple ...
Known for
Eac | Recurrence Achieving | Year Crim | High-Grade Dysplasia
KOL-Index: 55 This article reviews progress in chemopreventive drug development, especially data and concepts that are new since the 2002 AACR report on treatment and prevention of intraepithelial neoplasia. Molecular biomarker expressions involved in mechanisms of carcinogenesis and genetic progression models of intraepithelial neoplasia are discussed and analyzed for how they can inform mechanism-based, ...
Known for
Updates | Molecular Biomarker Expressions | Public-Private Partnerships | 10 Target Organ Sites
KOL-Index: 48 BACKGROUND & AIMS: Tethered capsule endomicroscopy (TCE) involves swallowing a small tethered pill that implements optical coherence tomography (OCT) imaging, procuring high resolution images of the whole esophagus. Here, we demonstrate and evaluate the feasibility and safety of TCE and a portable OCT imaging system in patients ...
Known for
High-Quality Oct Images | Nlmcategoryconclusionsthe Capabilities | Small Tethered Pill | Lengths
KOL-Index: 45 BACKGROUND: Probe-based confocal laser endomicroscopy (pCLE) provides microscopic imaging during an endoscopic procedure. Its introduction as a standard modality in gastroenterology has brought significant progress in management strategies, affecting many aspects of clinical care and requiring standardisation of practice and training. OBJECTIVE: This study aimed to provide guidance on the ...
Known for
Microscopic | 77 Statements | Leaders | Management Strategies
KOL-Index: 37 PURPOSE: T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive disease, affecting children and adults. Chemotherapy treatments show high response rates but have debilitating effects and carry risk of relapse. Previous work implicated NOTCH1 and other oncogenes. However, direct inhibition of these pathways affects healthy tissues and cancer alike. Our goal in this work has been to ...
Known for
T-All Growth | Jmjd3 Histone Demethylase | Turn | Notch1 Druggable Partners
KOL-Index: 9 Improvements in narrow band imaging (NBI) may provide an improved view of colonic mucosa for detection of polyps and adenomas. In this issue, Leung et al. report findings to suggest that this next-generation NBI technology is superior to conventional high-definition white light endoscopy in polyp detection. These findings are based on brighter illumination, which has been a problem with ...
Known for
Next-Generation Nbi Technology | Narrow Band Imaging | Conventional High-Definition White Light | Second-Generation Nbi
KOL-Index: 7 Esophageal adenocarcinoma risk in Barrett's esophagus (BE) is increased 30- to 125-fold versus the general population. Among all BE patients, however, neoplastic progression occurs only once per 200 patient-years. Molecular biomarkers are therefore needed to risk-stratify patients for more efficient surveillance endoscopy and to improve the early detection of progression. We therefore ...
Known for
Validation Methylation | Multicenter Blinded | Endoscopy Early | Auc Year
KOL-Index: 6 Repeated laser therapy has become an accepted therapeutic approach in the treatment of watermelon stomach, and to date no important negative sequelae have been reported. The case of a patient who underwent repeated sessions of neodymium: yttrium aluminum garnet (Nd:YAG) laser therapy over a five-year period for the treatment of the watermelon stomach is presented. Postlaser therapy the ...
Known for
Repeated Laser Therapy | Neodymium | Yttrium Aluminum Garnet | Accepted Therapeutic Approach
KOL-Index: 4 BACKGROUND: Barrett's esophagus, a condition of intestinal metaplasia of the esophagus, is associated with an increased risk of esophageal adenocarcinoma. We assessed whether endoscopic radiofrequency ablation could eradicate dysplastic Barrett's esophagus and decrease the rate of neoplastic progression. METHODS: In a multicenter, sham-controlled trial, we randomly assigned 127 patients with ...
Known for
Dysplasia Eradication | Radiofrequency | Nct00282672 | Metaplasia Esophagus

Mayo Clinic, Rochester, Minnesota, USA.

© 2022 - Key Opinion Leaders -
Key Opinion Leaders, LLC ,
2025 NW 102 Avenue, Suite 111 Doral , FL   33172