Michael Camilleri

Michael Camilleri

Department Of Immunology, Mayo Clinic College Of Medicine, Rochester, Minnesota, Usa., Department Of Dermatology, Sir Paul Boffa Hospital, Floriana, Malta., Department Of ...

Direct Impact

Concepts for which Michael Camilleri has direct influence:

bowel syndrome
colonic transit
gastric emptying
functional constipation
electrical stimulation
bile acid
insulin sensitivity

External impact

Concepts related to the work of other authors for which Michael Camilleri has influence:

vivo anakinra
paraneoplastic pemphigus
skin lesions
schnitzler syndrome
cytokines production
splenic b-cell lymphoma
bronchiolitis obliterans

Prominent publications by Michael Camilleri

KOL-Index: 33 The purpose of this review is to provide insight and clarification in the quandary of classification and delineate clinical and histological features and pathophysiology of paraneoplastic pemphigus. This is a paraneoplastic disease of epithelial autoimmunity and adhesion originally described by Dr. Anhalt in 1990. Paraneoplastic pemphigus represents only one manifestation of the ...
Known for
Mucocutaneous Pemphigus | Paraneoplastic Epithelial
KOL-Index: 14 Abstract: Schnitzler syndrome is a rare and underrecognized syndrome characterized by chronic urticaria, a monoclonal protein, and a variety of other symptoms, including fever, bone pain, organomegaly, and evidence of an acute phase response. Biopsy of an involved area of the skin shows a neutrophilic infiltrate without evidence of vasculitis or hemorrhage. Although the etiology of the ...
Known for
Schnitzler | Syndrome Monoclonal | Dermatosis Autoinflammatory | Anakinra
KOL-Index: 11 Dermatitis herpetiformis (DH) is an autoimmune blistering skin disorder that is associated with gluten sensitivity. It presents as a papulovesicular rash and is often associated with enteropathy. The rash resolves when the patient is placed on a gluten-free diet and/or dapsone. DH, as well as celiac disease, is tightly associated with DQ2 and DQ8. A novel mouse model for DH is described that ...
Known for
Small-Bowel | Dq8 Mice | Gliadin | Dermal-Epidermal Junction
KOL-Index: 8 To better understand the interactions between nanoparticulated whey protein (NWP) and other milk proteins during acidification, milk model systems were diluted to 0.5% protein concentration and adjusted to pH of 6.0–4.5 following homogenisation and heat treatment. The diluted systems with different concentrations of NWP (0–0.5%) were characterised in terms of particle size, viscosity, ...
Known for
Nwp Milk | Higher Surface Hydrophobicity | Acidification | Early Self-Association
KOL-Index: 7 BackgroundEluxadoline, a peripherally acting, mixed µ- and κ-opioid receptor (OR) agonist and δ-OR antagonist, is approved for treatment of adults with irritable bowel syndrome-diarrhea (IBS-D). About a third of IBS-D patients has bile acid diarrhea (BAD); opioids may stimulate TGR5 (bile acid) receptors.AimTo evaluate eluxadoline’s efficacy on altered bowel functions and safety in IBS-D ...
Known for
Urgent Bowel Movements | Increased Primary Fecal Bas | Aimto | Eluxadoline’s
KOL-Index: 2 This is a single-center, randomized, double blind, placebo-controlled study evaluating the effects of placebo, codeine, methylnaltrexone and codeine with methylnaltrexone on gastrointestinal motility and colonic transit of solids in healthy human subjects.The hypotheses are:Methylnaltrexone administered subcutaneously enhances gastrointestinal motility with acceleration of overall colonic ...
Known for
Bowel Pattern
KOL-Index: 2 The general aim of the current study is to describe the effect of pregabalin on colonic and sensory functions in adults with constipation predominant irritable bowel syndrome (IBS-C).Study hypotheses:Single-dose pregabalin 200mg increases sensation thresholds and decreases sensation ratings in response to balloon distension in the colon relative to pre-pregabalin treatment.Single-dose ...
Known for
Balloon Distension | Pain Vas | Adults Constipation | Period Operating
KOL-Index: 2 This will be a single-center, randomized, parallel group, multiple dose administration, double-blind, placebo-controlled study to evaluate the effects of YKP10811 on gastric, small bowel, and colonic transit in patients with Chronic Constipation or Functional Constipation. Four groups including a placebo group will be enrolled and will receive multiple oral doses of YKP10811 or matching ...
Known for
Colonic Transit | Phase Single | Groups Period | Evaluate Effects
KOL-Index: 2 This research study was being done to study the effect of codeine and Naloxegol for 3 days compared to placebo on the movement of food through the colon of healthy individuals. Codeine is a commonly used pain-relieving drug that often causes constipation as an unwanted side effect. Naloxegol is a medication recently approved by the FDA for treatment of constipation induced by Codeine.The ...
Known for
Troublesome Constipation | Effective Medications | Addictive Potential | Motility Disorders

Department of Immunology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA., Department of Dermatology, Sir Paul Boffa Hospital, Floriana, Malta., Department of Dermatology, and, Department of Internal Medicine, Mayo Clinic College of Medic

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