 | George A C MurrellShow email addressOrthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Sydney, New South Wales, Australia | Orthopaedic Research Institute, St. George ... |
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George A C Murrell:Expert Impact
Concepts for whichGeorge A C Murrellhas direct influence:Rotator cuff,Nitric oxide,Rotator cuff repair,Cuff repair,Achilles tendon,Tendon healing,6 months,Postoperative pain.
George A C Murrell:KOL impact
Concepts related to the work of other authors for whichfor which George A C Murrell has influence:Rotator cuff,Nitric oxide,Shoulder pain,Fracture healing,Oxidative stress,Achilles tendon,Articular cartilage.
KOL Resume for George A C Murrell
| Year | |
|---|---|
| 2021 | Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Sydney, New South Wales, Australia |
| 2020 | Orthopaedic Research Institute, St. George Hospital Campus, University of New South Wales, Sydney, Australia |
| 2019 | Orthopaedic Research Institute, St George Hospital Clinical School, University of New South Wales, Sydney, NSW, Australia |
| 2018 | Department of Orthopaedic Surgery, St George Hospital, Kogarah, NSW, Australia. Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Kogarah, NSW, Australia |
| 2017 | Orthopaedic Research Institute, St. George Hospital Campus, University of New South Wales, Sydney, New South Wales, Australia, |
| 2016 | Orthopaedic Research Institute, University of New South Wales, St George Hospital, Sydney, NSW, Australia |
| 2015 | The Orthopaedic Research Institute, Research & Education Centre, University of New South Wales, St George Hospital Campus, Kogarah, Sydney, NSW, Australia. Orthopaedic Research Institute, St George Hospital, University of New South Wales, Sydney, New South Wales, Australia |
| 2014 | Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Kogarah, New South Wales, Australia |
| 2013 | Orthopaedic Research Institute, St George Hospital, Kogarah, NSW, Australia |
| 2012 | Department of Orthopaedic Surgery, Orthopaedic Research Institute, University of New South Wales, St. George Hospital Campus, Kogarah, Sydney, NSW 2217, Australia |
| 2011 | Sports Medicine and Shoulder Service, Orthopaedic Research Institute, St. George Hospital Campus, University of New South Wales, Sydney, Australia |
| 2010 | From the *Department of Orthopaedics, Sahlgrenska University Hospital, Gothenburg University, Gothenburg, Sweden; and †Department of Orthopaedics Surgery, The University of New South Wales St. George Hospital Campus, New South Wales, Australia. Orthopedic Research Institute Department of Orthopaedics, St George Hospital |
| 2009 | Department of Orthopaedic Surgery, Orthopaedic Research Institute, St George Hospital Campus University of New South Wales, |
| 2008 | Department of Orthopaedic Surgery, St. George Hospital, Sydney, Australia |
| 2007 | Sports Medicine and Shoulder Service, Orthopaedic Research Institute, St George Hospital Campus, University of New South Wales, Sydney, New South Wales, Australia |
| 2006 | Orthopaedic Research Institute, St. George Hospital Campus, University of New South Wales, Kogarah, Sydney, New South Wales 2217, Australia. Telephone: 61‐2‐93502827; Fax: 61‐2‐93503967. |
| Concept | World rank |
|---|---|
| labra shoulder joint | #1 |
| interposition graft repairs | #1 |
| achilles tendon division | #1 |
| cuff surgical | #1 |
| biodegradable tack | #1 |
| row tension | #1 |
| baseline gel pack | #1 |
| role acl reconstruction | #1 |
| independent predictors case | #1 |
| weave technique | #1 |
| arthroscopy gold standard | #1 |
| isoforms fracture healing | #1 |
| messenger achilles | #1 |
| combined external rotation | #1 |
| normanhurst | #1 |
| meniscectomized joints decreased | #1 |
| frog glue load | #1 |
| overhead shoulder | #1 |
| collagen iiialpha1 | #1 |
| denatured aureus | #1 |
| ≥2 years surgery | #1 |
| failure biomechanical properties | #1 |
| immunohistochemistry motion | #1 |
| release idiopathic | #1 |
| motion subjective pain | #1 |
| rcr acromioplasty | #1 |
| fibrochondral region | #1 |
| volume repetitive load | #1 |
| 6 months decline | #1 |
| interpositional repairs | #1 |
| 2 age diabetes | #1 |
| neovascularization neoinnervation | #1 |
| n6 technique | #1 |
| technique synthetic ptfe | #1 |
| repairs suture | #1 |
| rehabilitation optimization | #1 |
| achilles tendon afi | #1 |
| inoscdna | #1 |
| painful stiff shoulders | #1 |
| routine shoulder examination | #1 |
| × tear | #1 |
| prolotherapy corticosteroid | #1 |
| ovine medial meniscectomy | #1 |
| repairs anchor technique | #1 |
| eptfe patch repair | #1 |
| 24 36 tendons | #1 |
| months rotator | #1 |
| failure testing instron | #1 |
| blue staining intensity | #1 |
| patientdetermined outcomes | #1 |
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Prominent publications by George A C Murrell
BACKGROUND: Symptomatic rotator cuff tears are often treated surgically. However, there is a paucity of information regarding the outcomes of revision arthroscopic rotator cuff repairs.
PURPOSE: To evaluate the outcome of revision arthroscopic rotator cuff surgery when compared with primary arthroscopic rotator cuff surgery in a large cohort of patients.
STUDY DESIGN: Cohort study; Level of evidence, 3.
METHOD: A consecutive series of 50 revision arthroscopic rotator cuff repairs ...
| Known for Cuff Repair | 2 Years | Arthroscopic Rotator | Primary Revision | Shoulder Function |
Rotator Cuff Repair: An Ex Vivo Analysis of Suture Anchor Repair Techniques on Initial Load to Failure
[ PUBLICATION ]
PURPOSE: To determine the best combination of anchors and suture techniques for repairing torn rotator cuff tendons.
TYPE OF STUDY: Ex vivo biomechanical investigation.
METHODS: Sixty fresh-frozen sheep infraspinatus tendons were repaired using 6 different repair techniques: transosseous sutures with 2 sutures and mattress stitches; 2 suture anchors with 1 suture per anchor using either simple stitches, mattress stitches, or modified Kessler stitches; 2 suture anchors with 2 sutures per ...
| Known for Cuff Repair | Suture Anchors | Simple Stitches | Mattress Stitch | Load Failure |
Tendon healing is a complex and highly-regulated process that is initiated, sustained and eventually terminated by a large number and variety of molecules. Growth factors represent one of the most important of the molecular families involved in healing, and a considerable number of studies have been undertaken in an effort to elucidate their many functions. This review covers some of the recent investigations into the roles of five growth factors whose activities have been best ...
| Known for Growth Factors | Ligament Healing | Pdgf Tgfβ | Factor Tendon | Cellular Migration |
Ultrasound-Guided Versus Blind Subacromial Corticosteroid Injections for Subacromial Impingement Syndrome
[ PUBLICATION ]
BACKGROUND: Subacromial corticosteroid injections are frequently performed for impingement syndrome of the shoulder. To improve the accuracy of injections, ultrasound can be used.
PURPOSE: To assess the clinical outcome of ultrasound-guided subacromial injections compared with blind subacromial injections for subacromial impingement syndrome.
STUDY DESIGN: Randomized controlled clinical trial; Level of evidence, 1.
METHODS: A total of 56 shoulders with subacromial impingement syndrome ...
| Known for Subacromial Impingement Syndrome | Corticosteroid Injections | 6 Weeks | Injection Blind | Ultrasound Guidance |
BACKGROUND: The rate of retears after rotator cuff repair varies from 11% to 94%. A retear is associated with poorer subjective and objective clinical outcomes than intact repair.
PURPOSE: This study was designed to determine which preoperative and/or intraoperative factors held the greatest association with retears after arthroscopic rotator cuff repair.
STUDY DESIGN: Cohort study; Level of evidence, 3.
METHODS: This study retrospectively evaluated 1000 consecutive patients who had ...
| Known for Rotator Cuff | 6 Months | Operative Time | Tissue Quality | Tear Size |
Repair of Partial-Thickness Rotator Cuff Tears: A Biomechanical Analysis of Footprint Contact Pressure and Strength in an Ovine Model
[ PUBLICATION ]
PURPOSE: The purpose of this study was to determine whether transtendon repair by use of a novel small-diameter knotless anchor showed enhanced mechanical properties compared with tear completion and repair.
METHODS: Articular-sided partial-thickness tears were created ex vivo in the infraspinatus of 24 ovine shoulders. The specimens were randomized into 4 groups of 6 each: (1) no repair, (2) transtendon repair, (3) completion of tear with tension-band single-row repair, and (4) ...
| Known for Ovine Model | Rotator Cuff | Transtendon Repair | Footprint Contact Pressure | Biomechanical Analysis |
The cell specific temporal expression of nitric oxide synthase isoforms during Achilles tendon healing
[ PUBLICATION ]
Abstract.Objective and design: We have previously shown that nitric oxide synthase (NOS) activity is upregulated following tendon injury, and that this activity is important to Achilles tendon healing. The aim of this study was to identify the cellular distribution of nitric oxide synthase isoforms during tendon healing.¶Material or subjects: Surgical division of the right Achilles tendon was performed in eighty-five male Sprague-Dawley rats. Healing Achilles tendons were harvested at 4, ...
| Known for Achilles Tendon | Nitric Oxide | Synthase Isoforms | Messenger Rats | Mrna Protein |
Mode of failure for rotator cuff repair with suture anchors identified at revision surgery
[ PUBLICATION ]
Rotator cuff tears are a common cause of shoulder pain and dysfunction. After surgical repair, there is a significant re-tear rate (25%-90%). The aim of this study was to determine the primary mode of mechanical failure for rotator cuffs repaired with suture anchors at the time of revision rotator cuff repair. We prospectively followed 342 consecutive torn rotator cuffs, repaired by a single surgeon using suture anchors and a mattress-suturing configuration. Of those shoulders, 21 (6%) ...
| Known for Suture Anchors | Revision Surgery | Rotator Cuff | Failure Tendon | Primary Repair |
BACKGROUND: Rotator cuff repair has a relatively high (20%-90%) chance of retears. Patients with an intact rotator cuff 6 months after surgery have better subjective and objective outcomes at 6 months and 2 years after rotator cuff repair than those who do not have an intact repair.
PURPOSE: The aim of this study was to determine if, and if so which, intraoperative factors predict an intact repair 6 months after rotator cuff repair.
STUDY DESIGN: Cohort study; Level of evidence, ...
| Known for Cuff Repair | Retear Rate | Tear Size | 6 Months | Tendon Quality |
A Comparison of Outcomes After Arthroscopic Repair of Partial Versus Small or Medium-Sized Full-Thickness Rotator Cuff Tears
[ PUBLICATION ]
BACKGROUND: Little is known about the outcomes after repair of partial-thickness rotator cuff tears. The aim of this study was to assess the outcome after repair of partial-thickness rotator cuff tears compared with full-thickness tears. Our hypothesis was that repair of partial-thickness tears leads to more shoulder stiffness but fewer retears compared with repair of full-thickness tears.
METHODS: A group of 105 consecutive patients who had a full-thickness tear measuring <3 cm2 was ...
| Known for Cuff Tears | Arthroscopic Repair | Thickness Rotator | Months Surgery | Shoulder Stiffness |
The aim of this study was to evaluate the effects of immobilization and mobilization on the functional and biomechanical recovery of injured Achilles tendons. Male Sprague-Dawley rats were allocated randomly into four groups: (a) sham operation, (b) division only (surgical transection of the Achilles tendon without immobilization), (c) "dummy" external fixation (division of the Achilles tendon and application of Kirschner wires), and (d) rigid external fixation (division of the Achilles ...
| Known for Achilles Tendon | Rat Model | Functional Performance | Effects Immobilization | Day Animals |
The Relationship Between Intraoperative Tear Dimensions and Postoperative Pain in 1624 Consecutive Arthroscopic Rotator Cuff Repairs
[ PUBLICATION ]
BACKGROUND: Rotator cuff repair often results in significant pain postoperatively, the cause of which is undetermined. Purpose/Hypothesis: The aim of this study was to evaluate the relationship between rotator cuff tear area and postoperative pain in patients who had undergone arthroscopic rotator cuff repair. We hypothesized that larger tears would be more painful because of elevated repair tension at 1 week postoperatively but that smaller tears would be more painful because of a ...
| Known for Postoperative Pain | Rotator Cuff | 6 Months | Smaller Tears | Tear Size |
Tension, abduction, and surgical technique affect footprint compression after rotator cuff repair in an ovine model
[ PUBLICATION ]
INTRODUCTION: Shoulder motion after rotator cuff repair may result in changes in tension and contact pressure at the repair site. Our goal was to determine how tension and motion affect a repair and what type of repair best tolerates these variables.
METHODS: Rotator cuff tears were created ex vivo in 30 ovine shoulders divided into 5 groups: single-row repair, double-row repair, tension-band repair, suture bridge repair, and double-row tension-band repair. A pressure probe was passed ...
| Known for Rotator Cuff | Contact Pressure | Ovine Model | Surgical Technique | Footprint Compression |
Predisposing factors for shoulder stiffness after rotator cuff repair have yet to be determined. The potential for recovery of range of motion and amelioration of pain in patients with this complication also remains unclear. Accordingly, data collected prospectively for 209 patients with a primary rotator cuff repair were retrospectively reviewed. Two groups, Group A (early motion recovery) and Group B (shoulder stiffness), were selected according to passive shoulder range of motion ...
| Known for Shoulder Stiffness | Rotator Cuff Repair | Range Motion | 6 Weeks | Cuff Injuries |
Nitric Oxide in Skeletal Muscle: Inhibition of Nitric Oxide Synthase Inhibits Walking Speed in Rats
[ PUBLICATION ]
Nitric oxide (NO*) is a multifunctional messenger molecule generated by a family of enzymes called the nitric oxide synthases (NOSs). Although NOSs have been identified in skeletal muscle, specifically brain NOS (bNOS) and endothelial NOS (eNOS), their role has not been well clarified. The goals of this investigation were to (1) characterize the immunoreactivity, Ca(2+) dependence, and activity of NOS in human and rat skeletal muscle and (2) using a rat model, investigate the effect of ...
| Known for Skeletal Muscle | Nitric Oxide | Synthase Type | Methyl Ester | Enzyme Inhibitors |
