• Disease
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  • Chapter 66
  • Chapter 66 Biperiden
  • Luiz Henrique Junqueira Dieckmann

    Prominent publications by Luiz Henrique Junqueira Dieckmann

    KOL Index score: 4246

    Cocaine use affects approximately 13.4 million people, or 0.3% of the world's population between 15 and 64 years of age. Several authors have described drug addiction as a disease of the brain reward system. Given that the cholinergic system impacts reward mechanisms and drug self-administration, acetylcholine (ACh) might play an important role in the cocaine addiction process. We evaluated the efficacy of biperiden (a cholinergic antagonist) in reducing craving and the amount used, and ...

    Also Ranks for: Treatment Cocaine |  drug addiction |  controlled trial |  muscarinic antagonists |  rating scales
    KOL Index score: 1770

    CONTEXTO: A disfunção sexual é frequente entre pacientes com esquizofrenia, sendo relatada como um dos mais incômodos efeitos adversos dos antipsicóticos, e está diretamente relacionada com adesão ao tratamento. OBJETIVOS: a) avaliar a acurácia da Escala de Experiência Sexual do Arizona (ASEX) para identificar a disfunção sexual; b) avaliar a frequência da disfunção sexual em uma amostra de pacientes do espectro da esquizofrenia em tratamento com antipsicóticos; e c) investigar o efeito ...

    KOL Index score: 1353

    OBJECTIVES: 1 - Verify the prevalence of depressive symptoms in first to fourth-year medical students using the Beck Depression Inventory (BDI). 2 - Establish correlations between target factors and higher or lower BDI scores. 3 - Investigate the relationship between the prevalence of depressive symptoms and the demand for psychological care offered by the Centro Universitário Lusíada. METHOD: Cross-sectional study of 290 first to fourth-year medical students; implementation of the BDI, ...

    Also Ranks for: Medical Students |  higher prevalence
    KOL Index score: 134

    Even though dopamine plays a central role in the reward system, other neurotransmitters are involved in the search for reinforcement. Cholinergic and dopaminergic systems together seem to coordinate the reinforcing function underlying drug consumption and addiction. Preclinical models including neurochemical and behavioral studies have shown effects of cholinergic agonists and antagonists on cocaine reinforcement. Recently, a double-blind placebo-controlled randomized study showed that ...


    Luiz Henrique Junqueira Dieckmann: Influence Statistics

    Sample of concepts for which Luiz Henrique Junqueira Dieckmann is among the top experts in the world.
    Concept World rank
    reinforcement cholinergic #3
    cocaine crack craving #3
    66 biperiden #3
    muscarinic antagonist addition #3
    chapter 66 biperiden #3
    adherence psychological therapy #3
    dependence clinical perspectives #3
    cocaine reinforcement biperiden #3
    addiction preclinical models #7
    biperiden muscarinic antagonist #9
    administration biperiden #9
    consumption cholinergic #11
    preclinical models effects #17
    drug consumption addiction #20
    search reinforcement #38
    damage beneficial #51
    dopaminergic circuit #68
    crack dependence #75
    reinforcing function #91
    addition adherence #97

    Key People For Chapter 66 Biperiden

    Top KOLs in the world
    Ira H Pastan
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    Alison M Goate
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    Shigetada Nakanishi
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    Deborah C Mash
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    †Michael J Kuhar
    dopamine transporter nucleus accumbens cart peptides
    M ‐Marsel Mesulam
    primary progressive aphasia alzheimer disease cholinergic neurons
    Select a search phrase   chapter 66 biperiden

    Luiz Henrique Junqueira Dieckmann:Expert Impact

    Concepts for whichLuiz Henrique Junqueira Dieckmannhas direct influence:Chapter 66 biperiden,  Cocaine reinforcement biperiden,  Cocaine crack,  Treatment cocaine,  Cocaine reinforcement,  Brazilian medical students,  Damage beneficial,  Reinforcing function.

    Luiz Henrique Junqueira Dieckmann:KOL impact

    Concepts related to the work of other authors for whichfor which Luiz Henrique Junqueira Dieckmann has influence:Sexual dysfunction,  Antipsychotic medication,  Chemical detoxification,  Psychiatric patients,  Suicidal behavior,  Brazilian medical students,  Threshold model.



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    Universidade Federal de São Paulo, São Paulo, Brazil | Department of Psychobiology, Universidade Federal de São Paulo, São Paulo, Brazil | Universidade Federal de São Paulo | Universidade Federal de São Paulo, São Paulo, Brasil