• breast cancer

    Prominent publications by Joe J Tjandra†

    KOL Index score: 13061

    PURPOSE: Although local excision of rectal cancers is a less morbid alternative to radical resection, its role as a curative procedure is unclear. The role of adjuvant therapy after local excision is also controversial. This review aims to examine current evidence on local excision of rectal cancers and how it fits into the management algorithm for rectal cancer.

    METHODS: A literature review was undertaken through the MEDLINE database and by cross-referencing previous publications, thus ...

    Also Ranks for: Local Excision |  rectal cancer |  neoplasm recurrence |  adjuvant therapy |  preoperative staging
    KOL Index score: 11600

    PURPOSE: This prospective study was designed to assess the effectiveness of sacral nerve stimulation for fecal incontinence in patients with external anal sphincter defect and to evaluate its efficacy regarding presence and size of sphincter defect.

    METHODS: Fifty-three consecutive patients who underwent sacral nerve stimulation for fecal incontinence were divided into two groups: external anal sphincter defect group (n = 21) vs. intact sphincter group (n = 32). Follow-up was performed ...

    Also Ranks for: Sacral Nerve Stimulation |  anal sphincter |  fecal incontinence |  quality life |  12 months
    KOL Index score: 11243

    Restorative proctocolectomy (RP) is generally considered to achieve better results in patients with familial adenomatous polyposis (FAP) than in those with mucosal ulcerative colitis (MUC). We studied 39 pairs of patients (FAP versus MUC), individually matched for surgeon (n = 4), types of ileal pouch (19 S-pouches and 20 J-pouches), technique of ileal pouch-anal anastomosis (21 stapled, 18 handsewn with mucosectomy), duration of follow-up after pouch function (median: 32 months; range: ...

    Also Ranks for: Restorative Proctocolectomy |  familial adenomatous polyposis |  mucosal ulcerative colitis |  patients muc |  ileal pouch
    KOL Index score: 11101

    OBJECTIVE: To assess which bowel preparation agent is most effective.

    METHODS: A search of randomized trials between January 1990 and July 2005 was obtained, using MEDLINE and PubMed databases, and the Cochrane Central Register of Controlled Trials. Meta-analysis was performed using the Forest plot review.

    RESULTS: Sodium phosphate (NaP) was more effective in bowel cleansing than polyethylene glycol (PEG) - odds ratio 0.75 (95%CI: 0.65-0.88; P = 0.0004); and sodium picosulphate (SPS) - ...

    Also Ranks for: Peg Nap |  bowel cleansing |  patients sps |  sodium phosphate |  preparation agent
    KOL Index score: 10808

    The operation of choice for complete rectal prolapse is controversial. We reviewed 169 patients undergoing 185 surgical procedures for rectal prolapse over a 27-year period. The most common surgical procedure employed was the Ripstein procedure (n = 142) and is the focus of this report. Other surgical procedures used included resection rectopexy (n = 18), anterior resection (n = 7), Altemeier's (n = 9), Delorme's (n = 2), and anal encirclement (n = 7). The median age was 59 years (range, ...

    Also Ranks for: Rectal Prolapse |  ripstein procedure |  fecal incontinence |  patients constipation |  resection rectopexy
    KOL Index score: 10725

    PURPOSE: Small-volume bowel preparation is better tolerated than 4-liter polyethylene glycol lavage. However, the efficacy of various small-volume bowel preparation agents for colonoscopy has not been clearly defined. This randomized, controlled trial was designed to compare oral sodium phosphate (Fleet) with Picoprep (sodium picosulfate-based preparation).

    METHODS: Two hundred twenty-five outpatients, aged 65 years or younger, who would undergo colonoscopy by two endoscopists were ...

    Also Ranks for: Oral Sodium Phosphate |  colonoscopy preparation |  fleet picoprep |  sodium picosulfate |  patient acceptability
    KOL Index score: 10475

    PURPOSE: The procedure for prolapse and hemorrhoids (stapled hemorrhoidopexy) has been introduced as an alternative to conventional hemorrhoidectomy. This is a systematic review on stapled hemorrhoidopexy of all randomized, controlled trials that have been published until August 2006.

    METHODS: All published, randomized, controlled trials comparing stapled hemorrhoidopexy to conventional hemorrhoidectomy were identified from Ovid MEDLINE, EMBASE, CINAHL, and all Evidence-Based Medicine ...

    Also Ranks for: Stapled Hemorrhoidopexy |  prolapse hemorrhoids |  conventional hemorrhoidectomy |  randomized controlled |  operating time
    KOL Index score: 10468

    INTRODUCTION: Chronic radiation proctitis complicating pelvic radiotherapy can be debilitating. It commonly presents with rectal bleeding, which can be difficult to control. Medical management of hemorrhagic radiation proctitis is not very successful, although surgery carries high risks. Thus, endoscopic treatments are preferred. The aim of this study is to assess the efficacy of argon plasma coagulation applied endoscopically to treat hemorrhagic radiation proctitis that has been ...

    Also Ranks for: Argon Plasma Coagulation |  radiation proctitis |  endoscopic treatment |  rectal bleeding |  pelvic radiotherapy
    KOL Index score: 10294

    PURPOSE: Fecal incontinence caused by a weak or disrupted internal anal sphincter is common but there has been no effective treatment. This prospective study evaluates the medium-term clinical effects of an injectable silicone biomaterial, PTP (Bioplastique), used to augment the internal anal sphincter.

    METHOD: Eighty-two patients (64 females; median age, 66 years) with severe fecal incontinence and a low anal resting pressure caused by internal anal sphincter dysfunction (defect, n = ...

    Also Ranks for: Fecal Incontinence |  silicone biomaterial |  internal anal |  sphincter dysfunction |  6 months
    KOL Index score: 10280

    PURPOSE: Rectocele is often associated with anorectal symptoms. Various surgical techniques have been described to repair the rectocele. The surgical results are variable. This study evaluated the results of transanal repair of rectocele, with particular emphasis on the impact of concomitant anismus on postoperative functional outcome.

    METHODS: Fifty-nine consecutive females who underwent transanal repair of rectocele for obstructed defecation were prospectively reviewed. All 59 patients ...

    Also Ranks for: Transanal Repair |  obstructed defecation |  functional outcome |  anorectal manometry |  physical examination
    KOL Index score: 10200

    PURPOSE: Although preoperative chemoradiation for high-risk rectal cancer may improve survival and local recurrence rate, its adverse effects are not well defined. This prospective study evaluated the use of preoperative chemoradiation for T3 and T4 resectable rectal cancer, with special emphasis on treatment morbidity, pathologic remission rate, quality of life, and anorectal function.

    METHODS: Forty-two patients (30 men, 12 women) were enrolled in the study. Median distance of the ...

    Also Ranks for: Rectal Cancer |  quality life |  preoperative chemoradiation |  percent patients |  distant metastases
    KOL Index score: 9907

    PURPOSE: This randomized study was designed to compare the effect of sacral neuromodulation with optimal medical therapy in patients with severe fecal incontinence.

    METHODS: Patients (aged 39-86 years) with severe fecal incontinence were randomized to have sacral nerve stimulation (SNS group; n = 60) or best supportive therapy (control; n = 60), which consisted of pelvic floor exercises, bulking agent, and dietary manipulation. Full assessment included endoanal ultrasound, anorectal ...

    Also Ranks for: Severe Fecal Incontinence |  nerve stimulation |  medical therapy |  incontinent episodes week |  quality life
    KOL Index score: 9857

    OBJECTIVE: Both injectable silicone biomaterial (PTQ) and pyrolytic carbon-coated beads (Durasphere) have been shown to be effective in treating passive faecal incontinence due to internal sphincter dysfunction. This is a randomized study to evaluate their relative safety and efficacy.

    METHOD: Forty patients (mean age 59.5 years vs 58.9 years) were randomized to have inter-sphincteric injection of PTQ or submucosal injection of Durasphere. Patients were assessed with anorectal ...

    Also Ranks for: Passive Faecal Incontinence |  ptq durasphere |  silicone biomaterial |  quality life |  submucosal injection
    KOL Index score: 9718

    PURPOSE: Although adjuvant chemoradiotherapy may improve outcomes after surgery for high-risk rectal cancer, its toxicities are not well documented. This is a review of complications associated with adjuvant therapy in randomized, controlled trials.

    METHODS: A MEDLINE and literature search was performed for randomized, controlled trials of adjuvant therapy for rectal cancer. Modalities of adjuvant therapy evaluated included preoperative radiotherapy, preoperative chemoradiotherapy, ...

    Also Ranks for: Adjuvant Chemotherapy |  postoperative radiotherapy |  quality life |  randomized controlled trials |  rectal cancer


    Joe J Tjandra†: Influence Statistics

    Sample of concepts for which Joe J Tjandra† is among the top experts in the world.
    Concept World rank
    ptp bioplastique #1
    surgical emergency rectum #1
    patients isolated defect #1
    injection ptq #1
    therapy proctitis #1
    54144 #1
    anus radiotherapy #1
    irritation difficulty #1
    odds nap #1
    defect external #1
    bowel cleansing ability #1
    haemorrhoids resting #1
    sps peg #1
    00001 incontinent #1
    equal majority #1
    rectoceles gynaecologist #1
    rectogesic agents adult #1
    injection ptq patients #1
    oral sodium phosphate #1
    asymptomatic hypokalaemia #1
    durasphere incontinence female #1
    incontinence medium #1
    groups fecal continence #1
    proctitis disease #1
    picoprep sodium #1
    sphincterotomy male #1
    injection silicone biomaterial #1
    8cm suprapubic incision #1
    anal pain throbbing #1
    anorectal physiologic testing #1
    parastomal lesions #1
    term wexner #1
    throbbing pruritus #1
    localized anterior defect #1
    clinic continence #1
    0016 injectable #1
    life function silicones #1
    colon toxic state #1
    46 10100 mmhg #1
    sphincterotomy coexisting #1
    ptq patients #1
    assisted ultralow #1
    pruritus irritation #1
    28 cadavers #1
    anorectal physiologic #1
    peg sps #1
    peg odds #1

    Key People For Breast Cancer

    Top KOLs in the world
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    breast cancer neoadjuvant chemotherapy estrogen receptors
    Rebecca L Siegel
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    Charles M Perou
    breast cancer gene expression intrinsic subtypes
    Freddie Ian Bray
    cancer incidence nordic countries mortality rates
    Jacques Ferlay
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    Joe J Tjandra†:Expert Impact

    Concepts for whichJoe J Tjandra†has direct influence:Breast cancer,  Rectal cancer,  Fecal incontinence,  Practice parameters,  Faecal incontinence,  Sacral nerve stimulation,  Dietary fiber,  Local excision.

    Joe J Tjandra†:KOL impact

    Concepts related to the work of other authors for whichfor which Joe J Tjandra† has influence:Rectal cancer,  Fecal incontinence,  Ulcerative colitis,  Local excision,  Laparoscopic surgery,  Sacral nerve stimulation,  Restorative proctocolectomy.



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    Authors' Affiliations: Divisions of 1Cancer Research and 2Cancer Surgery, 3Department of Pathology, and 4Centre for Molecular Imaging, Peter MacCallum Cancer Centre, 5Radiation Oncology Victoria, East Melbourne; 6Department of Surgery, University of