Justin Pijpe

Justin Pijpe

Department Of Oral & Maxillofacial Surgery, Special Dental Care And Orthodontics, Erasmus University Medical Center, Rotterdam, The Netherlands Department Of Oral & ...

Direct Impact

Concepts for which Justin Pijpe has direct influence:

salivary stones
labial biopsy
parotid gland
malt lymphoma
ridge preservation
implant placement
bone augmentation procedures

External impact

Concepts related to the work of other authors for which Justin Pijpe has influence:

response rates
sjögren’s syndrome
primary biliary cirrhosis
rheumatoid arthritis
indolent lymphomas
lasting remissions
botulinum toxin

Prominent publications by Justin Pijpe

KOL-Index: 28 OBJECTIVE: To investigate the safety and efficacy of B cell depletion treatment of patients with active primary Sjögren's syndrome of short duration (early primary SS) and patients with primary SS and mucosa-associated lymphoid tissue (MALT)-type lymphoma (MALT/primary SS). METHODS: Fifteen patients with primary SS were included in this phase II trial. Inclusion criteria for the early ...
Known for
Duration Early | Malt Lymphoma | Hacas Developed | Function Observed
KOL-Index: 23 The gain in knowledge regarding the cellular mechanisms of T and B lymphocyte activity in the pathogenesis of Sjögren's syndrome (SS) and the current availability of various biological agents (anti-TNF-alpha, IFN- alpha, anti-CD20, and anti-CD22) have resulted in new strategies for therapeutic intervention. In SS, various phase I and II studies have been performed to evaluate these new ...
Known for
Biological Agents | Cell-Related Therapies | Sjögrens Syndrome | Placebo-Controlled Trials
KOL-Index: 20 Over the past decade, facial cosmetic procedures have become more commonplace in dentistry and oral and maxillofacial surgery. An increasing number of patients seek minimal invasive procedures. One of the most requested procedures is treatment with botulinum toxin type A (BoNTA). Treatment of dynamic rhytids and lines with BoNTA is effective and produces high rates of improvement with rapid ...
Known for
Procedures Botulinum | Toxin Bonta | Facial Surgery
KOL-Index: 16 OBJECTIVE: To assess the effect of rituximab (anti-CD20 antibody) therapy on the (immuno)histopathology of parotid tissue in patients with primary Sjögren's syndrome (SS) and the correlation of histologic findings with the flow rate and composition of parotid saliva. METHODS: In a phase II study, an incisional parotid biopsy specimen was obtained from 5 patients with primary SS before and 12 ...
Known for
4 Infusions | Immunohistochemical Characterization | Initially Increased Salivary Sodium | Increased Salivary Flow Rate
KOL-Index: 15 OBJECTIVE: To identify a panel of protein and messenger RNA (mRNA) biomarkers in human whole saliva (WS) that may be used in the detection of primary Sjögren's syndrome (SS). METHODS: Mass spectrometry and expression microarray profiling were used to identify candidate protein and mRNA biomarkers of primary SS in WS samples. Validation of the discovered mRNA and protein biomarkers was also ...
Known for
27 Mrna | 16 Ws Peptides | Candidate Proteomic Genomic Biomarkers | 25 Ws Proteins
KOL-Index: 15 OBJECTIVE: To retrospectively analyze the clinical course of patients with mucosa-associated lymphoid tissue (MALT)-type lymphoma of the parotid gland and associated Sjögren's syndrome (SS). METHODS: All consecutive patients with SS and MALT lymphoma (MALT-SS) diagnosed in the University Medical Center Groningen between January 1997 and January 2009 were analyzed. Clinical course and ...
Known for
Severe Extraglandular Manifestations | 76 Months | Igm Rheumatoid Factor | 329
KOL-Index: 14 BACKGROUND: Salivary gland dysfunction is one of the key manifestations of Sjögren's syndrome. OBJECTIVES: (1) To assess prospectively loss of function of individual salivary glands in patients with primary and secondary Sjögren's syndrome in relation to disease duration and use of immunomodulatory drugs. (2) To study changes in sialochemical and laboratory values and subjective complaints ...
Known for
Baseline Duration | Individual Salivary Glands | Rates Time | Decreased Salivary Gland Function
KOL-Index: 13 PURPOSE: Leiomyosarcomas (LMS) of deep and superficial tissues were examined to identify prognostic markers explaining their different biological behaviour and to define differences between cutaneous and subcutaneous LMS. LMS and leiomyomas (LM) of the skin were compared to and consistent differences that could aid in the (sometimes difficult) diagnosis. PATIENTS: Material was obtained from ...
Known for
Biological Behaviour | Leiomyosarcomas | Difficult Diagnosis | Additional Criteria
KOL-Index: 13 The aim of this study was to estimate the accuracy and reproducibility of citric-acid-stimulated parotid saliva sampling. In healthy volunteers a strong correlation (r2 = 0.79) between flow rates from the left and right parotid gland was observed. In patients with Sjögren's syndrome this correlation (r2 = 0.90) was even stronger. The intraindividual variation in healthy volunteers was 23.3 ...
Known for
Stimulated Parotid | Left Flow | Estimate Repeated
KOL-Index: 12 There is limited information about the retention of lipiodol in the parotid gland after parotid gland sialography. This study assesses the prevalence of lipiodol retention after parotid sialography and determines if retention of lipiodol is related to the sialography technique or the underlying salivary gland pathology. Using the electronic hospital database (1996-2006), 66 out of 565 ...
Known for
Additional Radiographs | Radiographic Follow-Up | 42 Signs | 28 Months

Department of Oral & Maxillofacial Surgery, Special Dental Care and Orthodontics, Erasmus University Medical Center, Rotterdam, The Netherlands Department of Oral & Maxillofacial Surgery, Catharina Hospital Eindhoven, Eindhoven, The Netherlands

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