Tom R. DeMeester*

Tom R. DeMeester*

Department Of Surgery, Keck School Of Medicine, University Of Southern California, 1510 San Pablo Street, Suite 514, Los Angeles, Ca 90033-4612, Usa.

Direct Impact

Concepts for which Tom R DeMeester* has direct influence:

gastroesophageal reflux
intestinal metaplasia
esophageal adenocarcinoma
nissen fundoplication
barretts esophagus
cardiac mucosa
chest pain

External impact

Concepts related to the work of other authors for which Tom R DeMeester* has influence:

gastroesophageal reflux
intestinal metaplasia
esophageal cancer
nissen fundoplication
short esophagus
azygos vein
oxidative damage

Prominent publications by Tom R. DeMeester*

KOL-Index: 58 OBJECTIVES: Surveillance endoscopy has been recommended for patients with Barrett's esophagus; however, recent studies have questioned the importance owing to the new, lower, estimates of the rate of progression of Barrett's esophagus to cancer. The aim of the present study was to compare the tumor stage, survival, and frequency of esophageal preservation in patients who presented with ...
Known for
Survival Esophageal | Time Bias | 224 | Surveillance Stage
KOL-Index: 37 OBJECTIVES: The epidemiologic shift in esophageal cancer from squamous cell carcinoma to esophageal adenocarcinoma coincided with popularization of proton pump inhibitors and has focused attention on gastroesophageal reflux disease as a causative factor in this shift. The aim of this study is to review the literature on the rat reflux model in an effort to elucidate this phenomenon. METHODS: ...
Known for
Epidemiologic Shift | Acid-Suppression Therapy | Subsequent Esophageal Adenocarcinoma | Extensive Online Literature
KOL-Index: 35 A 75-year-old male with a long history of gastroesophageal reflux symptoms developed adenocarcinoma proximally within a long segment of Barrett's esophagus. He was taken for esophagectomy and gastric pull-up, but intraoperatively, he was found to have a marginal blood supply in the gastric tube. A temporary left-sided esophagostomy was created with the gastric tube sutured to the left ...
Known for
Intramucosal | Dysplasia Barrett
KOL-Index: 33 BACKGROUND: Carcinoembryonic antigen (CEA) and plasma DNA are known to be elevated in patients with esophageal cancer and are higher in patients with disseminated disease. The sensitivity and specificity of these markers in the diagnosis of recurrent esophageal cancer have not been compared. STUDY DESIGN: Plasma DNA was measured using polymerase chain reaction in 45 patients with esophageal ...
Known for
Cancer Carcinoembryonic | Sensitive Detecting | Serum Plasma | Higher Disseminated
KOL-Index: 32 The current status of carcinoma of the esophagus is reviewed, with specific discussions on current problems. These are difficulties in staging the disease, confusion in the classification, surgery vs. radiation therapy, palliative vs. curative resection, transthoracic vs. transhiatal resection for palliation, and stomach vs. colon as an esophageal substitute after resection. The importance ...
Known for
Esophagus Management | Resection Transthoracic | Therapy Palliative | Intubation Surgical
KOL-Index: 30 The successful performance of antireflux surgery is a significant therapeutic challenge. Simple reliance on patient symptomatology is inadequate to establish a diagnosis of gastroesophageal reflux and select patients for surgical therapy. Foregut symptoms are common and nonspecific. Not infrequently, gastroesophageal reflux disease can give rise to atypical symptoms, including asthma, chest ...
Known for
Minimally Invasive Procedure | Barretts Metaplasia | Therapeutic Challenge | Performance Antireflux
KOL-Index: 29 BACKGROUND: Mucosal ablation and endoscopic mucosal resection have been proposed as alternatives to surgical resection as therapy for intramucosal adenocarcinoma (IMC) of the esophagus. Acceptance of these alternative therapies requires an understanding of the clinical biology of IMC and the results of surgical resection modified for treatment of early disease. STUDY DESIGN: Retrospective ...
Known for
Esophagectomy Bloc | Alternative Therapies | 41 Nodes | 13 Women
KOL-Index: 28 Antireflux surgery with a magnetic sphincter augmentation device (MSAD) restores the competency of the lower esophageal sphincter with a device rather than a tissue fundoplication. As a regulated device, safety information from the published clinical literature can be supplemented by tracking under the Safe Medical Devices Act. The aim of this study was to examine the safety profile of the ...
Known for
Competency | Procedure-Related Interventions | Msad Gastroesophageal | Lower Esophageal Sphincter
KOL-Index: 26 The incidence of esophageal adenocarcinoma and adenocarcinoma of the gastric cardia has increased so substantially in the last two decades that adenocarcinoma now accounts for approximately one half of esophageal malignancies seen in the United States and Europe. The reasons for this histological change may be related to a parallel increase in the incidence of gastroesophageal reflux disease ...
Known for
Controversies Esophageal | Carcinoma Esophagus

Department of Surgery, Keck School of Medicine, University of Southern California, 1510 San Pablo Street, Suite 514, Los Angeles, CA 90033-4612, USA.

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