Peter C. M. van de Kerkhof

Peter C. M. van de Kerkhof

Department Of Dermatology, Radboud University Nijmegen Medical Centre, Nijmegen Centre For Molecular Life Sciences, 652 Ga, Nijmegen, The Netherlands

Direct Impact

Concepts for which Peter C M van de has direct influence:

scalp psoriasis
epidermal proliferation
normal skin
coal tar
calcipotriol ointment
atopic dermatitis
nocebo effects

External impact

Concepts related to the work of other authors for which Peter C M van de has influence:

severe psoriasis
atopic dermatitis
skin cancer
synovial fluid
liver biopsy
puerto rico
langerhans cells

Prominent publications by Peter C. M. van de Kerkhof

KOL-Index: 62 Importance: Few studies have examined watchful waiting (WW) in patients with basal cell carcinoma (BCC), although this approach might be suitable in patients who might not live long enough to benefit from treatment. Objective: To evaluate reasons for WW and to document the natural course of BCC in patients who chose WW and reasons to initiate later treatment. Design, Setting, and ...
Known for
Waiting Chosen | Component Prediction | Superficial Bccs | Carcinoma Bcc
KOL-Index: 56 The combination of calcipotriol (Cp) and topical corticosteroids increases efficacy and reduces side effects as compared to monotherapies. Previous studies suggest that such combinations may have an added value with respect to reduction of T-cell subsets. A two-compound product consisting of Cp and betamethasone dipropionate (BD) has become available for the treatment of psoriasis and is ...
Known for
Keratin 15 | 4 6 | Two-Compound Formulation | Topical Corticosteroids
KOL-Index: 54 BACKGROUND: Evidence-based recommendations for therapeutic decision making in childhood psoriasis are lacking. OBJECTIVES: We sought to systematically review all available literature concerning treatment efficacy and safety in childhood psoriasis and to propose a recommendation for topical and systemic treatment of childhood psoriasis. METHODS: Databases searched were PubMed, EMBASE, and the ...
KOL-Index: 43 Corticosteroids are the mainstay of topical therapies for the treatment of mild to moderate psoriasis. Selection of vehicle, concentrations of corticosteroid and coadministered medications, and frequency of administration are critical factors that enhance bioavailability of topical corticosteroids. Topical corticosteroids are commonly used as polytherapy and combination therapy with other ...
Known for
Combination Topical | Corticosteroid Coadministered Medications | Sprays | Therapies Psoriasis
KOL-Index: 41 Methotrexate is an established and highly effective systemic treatment for severe psoriasis, including the pustular and erythrodermic forms. It has been widely used during the last 3 decades. For this reason, the long term adverse effects of methotrexate are well known, in contrast to other relatively new systemic treatments like cyclosporin and retinoids. The most frequent adverse effects ...
Known for
Psoriasis Methotrexate | Systemic Severe
KOL-Index: 39 Importance: The number of very elderly (≥80 years) is rapidly growing worldwide. Basal cell carcinoma (BCC) are common in this age group and treatment is often challenging in this population. Objective: Obtaining an overview of the epidemiology and clinicopathological features of BCC in the very elderly to guide clinicians and policy makers. Evidence Review: A systematic review of literature ...
Known for
Elderly Prognostication | Features Bcc | Limited Heterogeneity | 000 Included
KOL-Index: 39 BACKGROUND: Most psoriasis patients suffering from mild to moderate disease are treated with first-line topical treatments, including corticosteroids, vitamin D analogues, topical retinoids and calcineurin inhibitors. Although evidence-based guidelines on combinations are lacking, the majority of patients will be treated with combinations of these popular topicals at some point during their ...
Known for
First-Line Treatments | Evidence-Based Guidelines | Potent Superpotent Corticosteroids | Once-Daily
KOL-Index: 37 Skin barrier function, confined to the stratum corneum, is traditionally evaluated using established, noninvasive biophysical methods like transepidermal water loss, capacitance and conductance. However, these methods neither measure skin molecular composition nor its structure, hindering the actual causes of skin barrier change or impairment. At the same time, confocal Raman ...
Known for
Time Confocal | Methods Actual | Cosmetic Skin | Noninvasive Biophysical

Department of Dermatology, Radboud University Nijmegen Medical Centre, Nijmegen Centre for Molecular Life Sciences, 652 GA, Nijmegen, The Netherlands

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