• Disease
  • Genital
  • Genital Herpes
  • Adrian Mindel

    Prominent publications by Adrian Mindel

    KOL Index score: 18819

    BACKGROUND: Cervical intraepithelial neoplasia grade 2 or greater (CIN2+) is the surrogate endpoint used in licensure trials of human papillomavirus (HPV) vaccines. Vaccine efficacy against CIN3+, the immediate precursor to invasive cervical cancer, is more difficult to measure because of its lower incidence, but provides the most stringent evidence of potential cancer prevention. We report vaccine efficacy against CIN3+ and adenocarcinoma in situ (AIS) in the end-of-study analysis of ...

    Also Ranks for: Vaccine Efficacy |  cervical intraepithelial |  cin3 ais |  patricia study |  hpv16 18
    KOL Index score: 14575

    BACKGROUND: An effective prophylactic vaccine would help control the spread of genital herpes.

    METHODS: We conducted two double-blind, randomized trials of a herpes simplex virus type 2 (HSV-2) glycoprotein-D-subunit vaccine with alum and 3-O-deacylated-monophosphoryl lipid A in subjects whose regular sexual partners had a history of genital herpes. In Study 1, subjects were seronegative for herpes simplex virus type 1 (HSV-1) and HSV-2; in Study 2, subjects were of any HSV serologic ...

    Also Ranks for: Genital Herpes |  hsv1 hsv2 |  efficacy study |  subjects vaccine |  2 human
    KOL Index score: 14114

    OBJECTIVE: To evaluate the efficacy and safety of a suppressive course of acyclovir in late pregnancy in women with recurrent genital herpes infection on the incidence of viral shedding, herpes lesion development and caesarean section for recurrent genital herpes.

    DESIGN: Double-blind, randomised placebo controlled clinical trial.

    SETTING: A department of genitourinary medicine in Sheffield and an antenatal clinic in London.

    POPULATION: Pregnant women with recurrent genital herpes ...

    Also Ranks for: Recurrent Genital |  herpes infection |  delivery women |  suppressive acyclovir |  late pregnancy
    KOL Index score: 12704

    OBJECTIVES: To examine the epidemiology of antibody to herpes simplex virus type 2 and to assess its suitability as a serological marker of sexual behaviour in populations with high and low prevalences.

    DESIGN: Cross sectional survey.

    SETTING: Department of genitourinary medicine and blood donation centre in central London.

    SUBJECTS: Representative sample of 869 patients attending department between November 1990 and December 1991, and 1494 consecutive blood donors attending for donation ...

    Also Ranks for: Type 2 |  herpes simplex |  sexual behaviour |  blood sample |  genitourinary medicine
    KOL Index score: 11997

    OBJECTIVES: To assess the prevalence of sexually transmitted infections (STIs) and blood borne viruses, risk behaviours, and demographics in women who have sex with women (WSW).

    METHODS: Retrospective cross sectional study using a multivariate model. Demographic, behavioural, and morbidity data were analysed from standardised medical records of patients attending a public STI and HIV service in Sydney between March 1991 and December 1998. All women with any history of sex with a woman ...

    Also Ranks for: Women Wsw |  sexually transmitted infections |  risk behaviours |  groups prevalence |  sexual partners
    KOL Index score: 11079

    We report final event-driven analysis data on the immunogenicity and efficacy of the human papillomavirus 16 and 18 ((HPV-16/18) AS04-adjuvanted vaccine in young women aged 15 to 25 years from the PApilloma TRIal against Cancer In young Adults (PATRICIA). The total vaccinated cohort (TVC) included all randomized participants who received at least one vaccine dose (vaccine, n = 9,319; control, n = 9,325) at months 0, 1, and/or 6. The TVC-naive (vaccine, n = 5,822; control, n = 5,819) had ...

    Also Ranks for: Human Papillomavirus |  young women |  hpv16 18 |  cervical infection |  adjuvanted vaccine
    KOL Index score: 10569

    OBJECTIVES: Syndromic management of sexually transmitted infections (STIs) omits asymptomatic infections, particularly among women. Accurate point-of-care assays may improve STI care in low- and middle-income countries (LMICs). We aimed to evaluate the diagnostic performance of the Xpert Chlamydia trachomatis/Neisseria gonorrhoeae (CT/NG) and OSOM Trichomonas vaginalis (TV) Test as part of a STI care model for young women in South Africa.

    DESIGN: Diagnostic evaluation conducted as part ...

    Also Ranks for: South Africa |  specificity xpert |  sti testing |  young women |  trichomonas infections
    KOL Index score: 10083

    OBJECTIVES: To assess prevalence of HIV and sexually transmitted infections (STIs), risk behaviours, and demographics in male commercial sex workers (CSWs)/prostitutes in Sydney.

    METHODS: Retrospective, cross sectional study with two comparison groups. Demographic, behavioural, and morbidity data were analysed from standardised medical records of patients attending a public STI and HIV service in Sydney between January 1991 and March 1998. Two comparison groups were used: female CSWs and ...

    Also Ranks for: Sexually Transmitted Infections |  risk behaviours |  sex work |  prevalence hiv |  retrospective studies
    KOL Index score: 9945

    BACKGROUND: Recently, outbreaks of anorectal lymphogranuloma venereum (LGV) have occurred among men who have sex with men (MSM). This study identifies risk factors and clinical predictors of LGV to determine the implications for clinical practice.

    METHODS: The Chlamydia trachomatis serovars for all MSM who had anorectal chlamydia diagnosed at a sexually transmitted infection clinic in Amsterdam, The Netherlands, in 2002 and 2003 were retrospectively typed; 87 persons were infected with ...

    Also Ranks for: Lgv Msm |  anorectal chlamydia |  lymphogranuloma venereum |  hiv seropositivity |  retrospective studies
    KOL Index score: 9690

    OBJECTIVES: Herpes simplex virus type 1 and type 2 (HSV-1 and HSV-2) are both highly prevalent. The rate of genital HSV-1 transmission is reportedly increasing over time. HSV-2 is considered to be an important risk factor for HIV transmission. We therefore studied changes in the HSV-1 and HSV-2 prevalence in a large cohort of men who have sex with men (MSM) over a 20-year time period.

    METHODS: Among 1847 HIV-infected and HIV-uninfected MSM participating in the Amsterdam Cohort Studies, ...

    Also Ranks for: Hsv1 Hsv2 |  herpes simplex |  type 1 |  hiv transmission |  human homosexuality
    KOL Index score: 9480

    BACKGROUND: Despite increasing reports of herpes simplex virus (HSV) type 1 (HSV-1)-associated anogenital herpes, there are very limited data comparing the seroepidemiological profile of and risk factors for HSV-1 and HSV type 2 (HSV-2) infection.

    METHODS: Sexual behaviors were examined as risk factors for prevalent and incident HSV-1 and HSV-2 infections in a community-based cohort of 1,427 HIV-negative gay men in Australia.

    RESULTS: The prevalence of HSV-1 and HSV-2 at baseline was 75% ...

    Also Ranks for: Herpes Simplex Virus |  hsv1 hsv2 |  prospective cohort |  casual partners |  incident infection
    KOL Index score: 9462

    BACKGROUND: Human immunodeficiency virus (HIV) seroadaptive behaviors, such as serosorting and strategic positioning, are being increasingly practised by homosexual men; however, their impact on sexually transmissible infections is unclear.

    METHODS: Participants were 1427 initially HIV-negative men enrolled from 2001 to 2004 and followed to June 2007. Participants were tested annually for anal and urethral gonorrhoea and chlamydia, herpes simplex virus, and syphilis. In addition, they ...

    Also Ranks for: Seroadaptive Behaviors |  strategic positioning |  uai serosorting |  sexually transmissible |  hiv risk
    KOL Index score: 9088

    To determine the relationship between antibodies to herpes simplex virus (HSV) types 1 and 2 and diagnosis of orolabial and genital herpes, a cross-sectional survey was done among 869 sexually transmitted disease clinic attendees and 1594 blood donors in London. Among clinic attenders, the prevalence of HSV-1 infection was 59.5% and that of HSV-2 infection was 22.7%, and among blood donors the prevalence was 44.6% and 7.6%, respectively. The sensitivity and specificity of a diagnosis of ...

    Also Ranks for: Herpes Simplex Virus |  hsv infection |  sensitivity specificity |  blood donors |  clinic attenders
    KOL Index score: 9017

    BACKGROUND/OBJECTIVE: Recent studies suggest that herpes simplex virus type 1 (HSV-1) is becoming more common as a cause for genital herpes, relative to HSV-2. We aimed to calculate trends in HSV type from isolates and serology samples sent to a reference virology laboratory in New South Wales (NSW), Australia.

    METHODS: We compared the proportions of HSV-1 and HSV-2 positive samples, adjusting for age and sex of source patient, in three datasets: anogenital isolates from 1979 to 1988; ...

    Also Ranks for: Simplex Virus Type |  hsv1 hsv2 |  human herpesvirus |  anogenital herpes |  sex factors
    KOL Index score: 8825

    OBJECTIVES: To ascertain how frequently general practitioners (GPs) in Australia encounter sexually transmitted infections (STIs), how STIs are managed in general practice, and the characteristics of GPs who manage STIs.

    METHODS: Data were derived from the Bettering the Evaluation and Care of Health (BEACH) database. BEACH is a cross sectional survey of national GP activity. Approximately 1000 GPs per year each record details of 100 consecutive patient encounters. Details from April 1998 ...

    Also Ranks for: Sexually Transmitted Infections |  characteristics gps |  100 encounters |  general practice |  genital herpes


    Adrian Mindel: Influence Statistics

    Sample of concepts for which Adrian Mindel is among the top experts in the world.
    Concept World rank
    treatment placebotreated patients #1
    13 september1993 #1
    ahmf website #1
    syndrome female gonorrhea #1
    male condoms prevention #1
    negative serology presentation #1
    sex bowel #1
    clinical recurrences episodes #1
    anal intraepithelial prognosis #1
    london std clinic #1
    highly sexual #1
    penis 467 64 #1
    pregnancy fellows #1
    confirming recurrences #1
    recurrences intravenous #1
    james pringle house #1
    cutaneous hepatitis #1
    serology genital herpes #1
    female condoms prevention #1
    viral cultures doctors #1
    common wsw #1
    gp age 95 #1
    breakage biological measures #1
    considers condom #1
    periostitis clinical features #1
    herpes attending #1
    subjects 123 patients #1
    nesb adult attitude #1
    acyclovir inosine pranobex #1
    pranobex acyclovir #1
    odds ratio delivery #1
    spontaneous loss parasite #1
    0001 doctors #1
    28 drugs patients #1
    herpes common #1
    true incidence reporting #1
    younger gp age #1
    shcs western sydney #1
    recurrences stress #1
    homosexual entamoeba #1
    sti nsw #1
    reporting difficulties #1
    neurological problems iridocyclitis #1
    acyclovir psychological #1

    Key People For Genital Herpes

    Top KOLs in the world
    Lawrence Corey
    simplex virus genital herpes south africa
    Anna Wald
    genital herpes simplex virus viral shedding
    Andre Joseph Nahmias
    herpes simplex united states newborn infant
    Rhoda L ASHLEY
    genital herpes simplex virus chronic fatigue
    Jacqueline K Benedetti
    genital herpes southwest oncology simplex virus
    Adrian Mindel
    genital herpes sexually transmitted infections south africa

    Adrian Mindel:Expert Impact

    Concepts for whichAdrian Mindelhas direct influence:Genital herpes,  New zealand,  Inosine pranobex,  New south wales,  Chlamydia testing,  Syndromic management,  Sexually transmitted infections,  South africa.

    Adrian Mindel:KOL impact

    Concepts related to the work of other authors for whichfor which Adrian Mindel has influence:Genital herpes,  Simplex virus,  Bacterial vaginosis,  Cervical cancer,  Hpv vaccination,  Sexually transmitted infections,  Hiv infection.



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    Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa | Centre for the AIDS Programme of Research in South Africa, South Africa. | Centre for the AIDS Programme of Research in South Africa (CAPRISA), Nelson R Mande