Kunshen Liu: Influence Statistics

Kunshen Liu

Kunshen Liu

The First Hospital of Hebei Medical University, Shijiazhuang, China. | The First Cardiology Division The First Hospital of Hebei Medical University Shijiazhuang China. | From ...

Kunshen Liu: Expert Impact

Concepts for which Kunshen Liu has direct influence: Endothelin receptor antagonists , Pulmonary arterial hypertension , Diuretic resistance , Cardiac surgery , Receptor antagonists , Endothelin receptor , Renal artery stenosis .

Kunshen Liu: KOL impact

Concepts related to the work of other authors for which for which Kunshen Liu has influence: Pulmonary arterial hypertension , Endothelin receptor antagonists , Rat plasma , Generic drugs , Pharmacokinetic study , Diuretic resistance , Simultaneous determination .

KOL Resume for Kunshen Liu

Year
2021

The First Hospital of Hebei Medical University, Shijiazhuang, China.

2020

The First Cardiology Division The First Hospital of Hebei Medical University Shijiazhuang China.

2015

From the Heart Center, The First Hospital of Hebei Medical University, Shijiazhuang, China.H. Meng, MD; G. Liu, MD, J. Zhai, MD; Y. Zhen, MD; Q. Zhao, MD; M. Zheng, MD; G. Ma, MD; L. Wang, MD; L. Tian, MD; L. Ji, MD; L. Duan, MD; L. Li, MD; K. Liu, MD; C. Liu, MD, The First Hospital of Hebei Medical University.

Heart Center, The First Hospital of Hebei Medical University, 89 Donggang Road, Shijiazhuang, Hebei Province 050031, China.

2014

Heart Center, The First Hospital of Hebei Medical University, Hebei Medical University, Shijiazhuang, China.

Department of Cardiology, The First Affiliated Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, P.R. China

2013

Heart Center, The First Hospital of Hebei Medical University, Hebei Province, China

2010

Heart Center, The First Hospital of Hebei Medical University, Hebei Medical University, Shijiazhuang, People's Republic of China

2009

First Hospital of Hebei Medical University, Shijiazhuang, Hebei, China

2008

Cardiology Department, Hebei Medical University

2007

Cardiology Department, First Hospital of Hebei Medical University, Hebei Medical University, Hebei, China

2006

From the Cardiology Department, Hebei Medical University, Shijiazhuang, Hebei.

The First Hospital of Hebei Medical University, Hebei Medical University, 89 Donggang Road, Shijiazhuang, Hebei Province 050031, People's Republic of China

2005

Cardiology Department, The First Affiliated Hospital of Hebei Medical University

Prominent publications by Kunshen Liu

KOL-Index: 18386 . BACKGROUND: Pulmonary arterial hypertension is a devastating disease, which leads to right heart failure and premature death. Recent evidence suggests that endothelin receptor antagonists may be promising drugs in the treatment of pulmonary arterial hypertension. OBJECTIVES: To evaluate the efficacy of endothelin receptor antagonists in pulmonary arterial hypertension. SEARCH STRATEGY: We ...
Known for Endothelin Receptor Antagonists | Pulmonary Arterial Hypertension | 95 Confidence Interval | Nyha Functional Class
KOL-Index: 16861 . BACKGROUND: Pulmonary arterial hypertension is a devastating disease, which leads to right heart failure and premature death. Recent evidence suggests that endothelin receptor antagonists may be promising drugs in the treatment of pulmonary arterial hypertension. OBJECTIVES: To evaluate the efficacy of endothelin receptor antagonists in pulmonary arterial hypertension. SEARCH METHODS: We ...
Known for Endothelin Receptor Antagonists | Pulmonary Arterial Hypertension | Functional Class | Irreversible Liver Failure
KOL-Index: 9120 . In heart failure, the renal responsiveness to exogenous and endogenous atrial natriuretic peptide (ANP) is blunted. The mechanisms of renal hyporesponsiveness to ANP are complex, but one potential mechanism is decreased expression of natriuretic peptide receptor-A (NPR-A) in inner medullary collecting duct (IMCD) cells. Newly emerging evidence shows that glucocorticoids could produce ...
Known for Heart Failure | Natriuretic Peptide | Renal Responsiveness | Wistar Receptors
KOL-Index: 8106 . Animal studies showed glucocorticoids could specifically dilate renal vasculature, regulate synthesis and release of atrial natriuretic peptide (ANP), upregulate ANP receptors on vascular endothelial cells, and thus have potent potentiating diuresis and natriuresis effects in animal studies; however, their diuretic efficacy in humans is yet to be known. Therefore, we designed this ...
Known for Heart Failure | Serum Creatinine | Diuretic Effects | Animal Studies
KOL-Index: 7973 . AIMS: cardiopulmonary bypass and cardiac surgery are associated with a significant systemic inflammatory response that has been suggested playing a causative role in the development of perioperative atrial fibrillation (POAF). The goal of this meta-analysis was to determine the efficacy of glucocorticoid prophylaxis in preventing POAF, or length of intensive care unite (ICU) or hospital ...
Known for Cardiac Surgery | Atrial Fibrillation | Poaf Length | Icu Stay
KOL-Index: 7680 . BACKGROUND: Chronic drug interactions that exist between symptomatic congestive heart failure (CHF) therapy and pharmacologic agents used for hyperuricemia and gout are a challenging problem in clinical practice. Recent observational studies showed that prednisone can induce a potent diuresis and lower serum uric acid concentration (SUA) in CHF. We therefore designed a randomized study to ...
Known for Uric Acid Lowering | Heart Failure | Clinical Status | Potent Diuresis
KOL-Index: 7571 . BACKGROUND: Refractory congestive heart failure (CHF) with diuretic resistance is life-threatening and predicts a short life expectancy. Glucocorticoids have been proven to have potent diuretic effects in animal studies; however, their efficacy in CHF patients with diuretic resistance is not known. METHODS: Thirteen CHF patients with significant volume overload and diuretic resistance who ...
Known for Diuretic Resistance | Renal Function | Chf Patients | Heart Failure
KOL-Index: 6812 . Atrial natriuretic peptide (ANP) provides a potent defense mechanism against volume overload in mammals. Its primary receptor, natriuretic peptide receptor-A (NPR-A), is localized mostly in the kidney, but also is found in hypothalamic areas involved in body fluid volume regulation. Acute glucocorticoid administration produces potent diuresis and natriuresis, possibly by acting in the ...
Known for Natriuretic Peptide | Wistar Receptors | Potent Diuresis | Renal Water
KOL-Index: 5883 . Diuretic resistance in heart failure is defined as a state in which diuretic response is diminished or lost before the therapeutic goal of relief from congestion has been reached. Diuretic resistance is very common and is associated with poor outcomes. Over the past decade, several new drugs and devices targeting decongestion and improvement in renal function in patients with heart failure ...
Known for Diuretic Resistance | Heart Failure | Glucocorticoid Therapy | Renal Function
KOL-Index: 4699 . Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is an inherited heart muscle disease associated with increased risks of sudden death, particularly in young, otherwise healthy, patients. The pathologic features are progressive myocardial atrophy and fibrofatty replacement. Plakophilin-2 (PKP2) is reported as the most common ARVD/C-causing gene in Western countries. In ...
Known for Pkp2 Mutations | Patients Arvd | Arrhythmogenic Ventricular | Sudden Death
KOL-Index: 4433 . OBJECTIVE: To determine the safety and efficacy of prednisone in patients with symptomatic heart failure (HF) and hyperuricemia. METHODS: Prednisone therapy was administered for a short time to 191 symptomatic HF patients with hyperuricemia (serum uric acid > 7 mg/dl). RESULTS: Prednisone significantly reduced serum uric acid by 2.99 mg/dl (p < 0.01) and serum creatinine by 0.17 mg/dl (p < ...
Known for Uric Acid | Heart Failure | Serum Creatinine | Urine Output
KOL-Index: 4119 . The aim of the present study was to determine if prednisone, a glucocorticoid, added to conventional treatment for patients with decompensated congestive heart failure (DCHF) refractory to the conventional care, results in significant relief of congestive symptoms and improvement of clinical status. Diuretic-based strategies, as the mainstay in DCHF management, are not always effective in ...
Known for Heart Failure | Potent Diuresis | Renal Function | Clinical Status
KOL-Index: 3943 . BACKGROUND: Recent evidence indicates that prednisone can potentiate renal responsiveness to diuretics in heart failure (HF). However, the optimal dose of prednisone is not known. METHOD: Thirty-eight patients with symptomatic HF were randomized to receive standard HF care alone (n = 10) or with low-dose (15 mg/d, n = 8), medium-dose (30 mg/d, n = 10), or high-dose prednisone (60 mg/d, n = ...
Known for Heart Failure | Dose Prednisone | Urine Output | Standard Hf
KOL-Index: 3927 . INTRODUCTION: Newly emerging evidence showed that glucocorticoids could potentiate natriuretic peptides' action by increasing the density of natriuretic peptide receptor A, leading to a potent diuresis and a renal function improvement in patients with acute decompensated heart failure (ADHF). Therefore, glucocorticoid therapy may be used in patients with ADHF. METHODS: One hundred two ...
Known for Heart Failure | Glucocorticoid Therapy | Serum Creatinine | Potent Diuresis

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The First Hospital of Hebei Medical University, Shijiazhuang, China. | The First Cardiology Division The First Hospital of Hebei Medical University Shijiazhuang China. | From the Heart Center, The First Hospital of Hebei Medical University, Shijiazhu