• KOL
    • Skeletal Muscle
    • Michaela Kjaer
    • Michaela Kjaer: Influence Statistics

      Michaela Kjaer

      Michaela Kjaer

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      Department of Orthopedic Surgery, Institute of Sports Medicine, Copenhagen University Hospital - Bispebjerg Frederiksberg, and Center for Healthy Aging, Faculty of Health and ...

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      Michaela Kjaer:Expert Impact

      Concepts for whichMichaela Kjaerhas direct influence:Skeletal muscle,Resistance training,Achilles tendon,Collagen synthesis,Blood flow,Mechanical properties,Physical activity,Muscle strength.

      Michaela Kjaer:KOL impact

      Concepts related to the work of other authors for whichfor which Michaela Kjaer has influence:Skeletal muscle,Resistance training,Achilles tendon,Physical activity,Blood flow,Extracellular matrix,Mechanical properties.

      KOL Resume for Michaela Kjaer

      Year
      2022

      Department of Orthopedic Surgery, Institute of Sports Medicine, Copenhagen University Hospital - Bispebjerg Frederiksberg, and Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

      2021

      Institute of Sports Medicine, Department of Orthopedic Surgery, Copenhagen University Hospital - Bispebjerg Frederiksberg, Copenhagen NV, Denmark.

      Center for Healthy Aging, Department of Clinical Medicine, University of Copenhagen, Denmark

      2020

      Institute of Sports Medicine Copenhagen, Department of Orthopedic Surgery, Bispebjerg Hospital, Copenhagen, Denmark.

      Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3, 2200 Copenhagen N, Denmark

      2019

      Institute of Sports Medicine, Bispebjerg Hospital and Center for Healthy Aging, University of Copenhagen, Copenhagen, Denmark

      2018

      Institute of Sports Medicine Copenhagen, Department of Orthopedic Surgery M, Bispebjerg Hospital and Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, DENMARK.

      Center for Healthy Aging, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen , Copenhagen , Denmark.

      Department of Physical Therapy, Musculoskeletal Rehabilitation Research Unit, Bispebjerg Hospital, Copenhagen, Denmark

      2017

      Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark

      Institute of Sports Medicine and Centre for Healthy Aging, Copenhagen University Hospital at Bispebjerg and Faculty of Health and Medical Sciences University of Copenhagen, Bispebjerg Bakke 23, 2400NV, Copenhagen NV, Dänemark

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      Sample of concepts for which Michaela Kjaer is among the top experts in the world.
      Concept World rank
      training reduction subjects #1
      tendon pet #1
      type mfa #1
      humans infrared spectroscopy #1
      isomvc #1
      periphery tendon injuries #1
      tendon collagen #1
      preex postex10 #1
      betaep highest values #1
      tracer phenylalanine #1
      controls fibril density #1
      p005 mhc #1
      emg rtd #1
      tendon mgf #1
      murf1 transcription bout #1
      exercise tendon #1
      control relative force #1
      regions specific ages #1
      tgfbeta1 response #1
      control sci subjects #1
      indirect contact fibroblasts #1
      turnover core #1
      increase sci #1
      adult life regions #1
      exercise hbe #1
      trapezius myalgia microdialysis #1
      muscle mtj #1
      humans achilles #1
      resistance exercise hl #1
      legs csa #1
      urine synovial fluid #1
      ic6 c6m #1
      exercise collagen #1
      collagen formation exercise #1
      peritendinous region #1
      rna sequencing immunofluorescence #1
      year resistance #1
      controls fibril morphology #1
      tendon force achilles #1
      glucosamine training #1
      gapdh pax7 #1
      human tendon nsaid #1
      young subjects correlation #1
      asymmetries dexterity #1
      chronic hyperglycemia hypercholesterolemia #1
      lox tendon csa #1
      067074 #1
      tendons young #1
      backgroundfibroblasts #1
      rehabilitation pattern #1
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      Prominent publications by Michaela Kjaer

      KOL-Index: 17840

      Collagens are the most abundant components of the extracellular matrix and many types of soft tissues. Elastin is another major component of certain soft tissues, such as arterial walls and ligaments. Many other molecules, though lower in quantity, function as essential components of the extracellular matrix in soft tissues. Some of these are reviewed in this chapter. Besides their basic structure, biochemistry and physiology, their roles in disorders of soft tissues are discussed only ...

      Known for Extracellular Matrix | Connective Tissues | Elastic Fibers | Basic Components | Protein Structure
      KOL-Index: 17075

      Tendon tissue and the extracellular matrix of skeletal muscle respond to mechanical loading by increased collagen expression and synthesis. This response is likely a secondary effect of a mechanically induced expression of growth factors, including transforming growth factor-beta1 (TGF-beta1) and insulin-like growth factor-I (IGF-I). It is not known whether unloading of tendon tissue can reduce the expression of collagen and collagen-inducing growth factors. Furthermore, the coordinated ...

      Known for Growth Factors | Rat Tendon | Expression Collagen | Muscle Tissue | Factor Beta1
      KOL-Index: 17042

      1. It has been established that pulmonary oxygen uptake is greater during cycle exercise in humans at high compared to low contraction frequencies. However, it is unclear whether this is due to more work being performed at the high frequencies and whether the energy turnover of the working muscles is higher. The present study tested the hypothesis that human skeletal muscle oxygen uptake and energy turnover are elevated during exercise at high compared to low contraction frequency when ...

      Known for Energy Turnover | Contraction Frequencies | Muscle Oxygen | Dynamic Exercise | 100 Rpm
      KOL-Index: 14569

      The extracellular matrix (ECM), and especially the connective tissue with its collagen, links tissues of the body together and plays an important role in the force transmission and tissue structure maintenance especially in tendons, ligaments, bone, and muscle. The ECM turnover is influenced by physical activity, and both collagen synthesis and degrading metalloprotease enzymes increase with mechanical loading. Both transcription and posttranslational modifications, as well as local and ...

      Known for Mechanical Loading | Extracellular Matrix | Skeletal Muscle | Role Ecm | Collagen Turnover
      KOL-Index: 14423

      Muscle protein turnover following resistance exercise and amino acid availability are relatively well described. By contrast, the beneficial effects of different sources of intact proteins in relation to exercise need further investigation. Our objective was to compare muscle anabolic responses to a single bolus intake of whey or casein after performance of heavy resistance exercise. Young male individuals were randomly assigned to participate in two protein trials (n = 9) or one control ...

      Known for Resistance Exercise | Protein Ingestion | Whey Casein | Control Trial | Greater Extent
      KOL-Index: 14109

      The expression of two isoforms of insulin-like growth factor-I (IGF-I): mechano growth factor (MGF) and IGF-IEa were studied in muscle in response to growth hormone (GH) administration with and without resistance training in healthy elderly men. A third isoform, IGF-IEb was also investigated in response to resistance training only. The subjects (age 74 +/- 1 years, mean +/- S.E.M) were assigned to either resistance training with placebo, resistance training combined with GH ...

      Known for Resistance Training | Mrna Expression | Growth Hormone | 12 Weeks | Gh Administration
      KOL-Index: 14029

      In skeletal muscle, an increased expression of insulin like growth factor-I isoforms IGF-IEa and mechano-growth factor (MGF) combined with downregulation of myostatin is thought to be essential for training-induced hypertrophy. However, the specific effects of different contraction types on regulation of these factors in muscle are still unclear, and in tendon the functions of myostatin, IGF-IEa, and MGF in relation to training are unknown. Female Sprague-Dawley rats were subjected to 4 ...

      Known for Contraction Types | Rat Muscle | Eccentric Training | Growth Factor | Myostatin Mrna
      KOL-Index: 13941

      Women are at greater risk than men for certain kinds of diseases and injuries, which may at least partly be caused by sex hormonal differences. We aimed to test the influence of estradiol in vivo on collagen synthesis in tendon, bone, and muscle. Two groups of young, healthy women similar in age, body composition, and exercise-training status were included. The two groups were either habitual users of oral contraceptives exposed to a high concentration of synthetic estradiol and ...

      Known for Collagen Synthesis | Oral Contraceptives | Connective Tissue | Young Women | Tendon Muscle
      KOL-Index: 13832

      We examined the effect of growth hormone (GH) on connective tissue of tendon and skeletal muscle during immobilisation and re-training in humans. Young men (20-30 years; n = 20) were randomly assigned to daily recombinant human GH (rhGH) (33-50 μg kg(-1) day(-1)) or placebo (Plc), and had one leg immobilised for 2 weeks, followed by 6 weeks of strength training. The cross-sectional area (CSA), maximal muscle strength (maximal voluntary contraction, MVC) and biomechanical properties of ...

      Known for Skeletal Muscle | Growth Hormone | Gh Plc | Gene Expression | 6 Weeks
      KOL-Index: 13582

      1. Circulation around tendons may act as a shunt for muscle during exercise. The perfusion and oxygenation of Achilles' peritendinous tissue was measured in parallel with that of calf muscle during exercise to determine (1) whether blood flow is restricted in peritendinous tissue during exercise, and (2) whether blood flow is coupled to oxidative metabolism. 2. Seven individuals performed dynamic plantar flexion from 1 to 9 W. Radial artery and popliteal venous blood were sampled for O2, ...

      Known for Blood Flow | Calf Muscle | Peritendinous Tissue | Dynamic Exercise | Dye Dilution
      KOL-Index: 13540

      Spinal cord injured (SCI) individuals most often contract their injury at a young age and are deemed to a life of more or less physical inactivity. In addition to the primary implications of the SCI, severe SCI individuals are stigmatized by conditions related to their physically inactive lifestyle. It is unknown if these inactivity related conditions are potentially reversible and the aim of the present study was, therefore, to examine the effect of exercise on SCI individuals. Ten such ...

      Known for Cycle Training | Sci Individuals | Skeletal Muscle | Electrically Induced | 1 Year
      KOL-Index: 13436

      1. Age-associated loss of skeletal muscle mass and strength can partly be counteracted by resistance training, causing a net synthesis of muscular proteins. Protein synthesis is influenced synergistically by postexercise amino acid supplementation, but the importance of the timing of protein intake remains unresolved. 2. The study investigated the importance of immediate (P0) or delayed (P2) intake of an oral protein supplement upon muscle hypertrophy and strength over a period of ...

      Known for Muscle Hypertrophy | Resistance Training | Protein Intake | Elderly Humans | Magnetic Resonance Imaging
      KOL-Index: 13187

      The aim of the present study was to simultaneously examine skeletal muscle heat production and ATP turnover in humans during dynamic exercise with marked differences in aerobic metabolism. This was done to test the hypothesis that efficiency is higher in anaerobic than aerobic ATP resynthesis. Six healthy male subjects performed 90 s of low intensity knee-extensor exercise with (OCC) and without thigh occlusion (CON-LI) as well as 90 s of high intensity exercise (CON-HI) that continued ...

      Known for Dynamic Exercise | Heat Production | Skeletal Muscle | Atp Turnover | Body Temperature
      KOL-Index: 13114

      Both tendon and peritendinous tissue show evidence of metabolic activity, but the effect of acute exercise on substrate turnover is unknown. We therefore examined the influence of acute exercise on glucose uptake in the patellar and quadriceps tendons during dynamic exercise in humans. Glucose uptake was measured in five healthy men in the patellar and quadriceps tendons and the quadriceps femoris muscle at rest and during dynamic knee-extension exercise (25 W) using positron emission ...

      Known for Glucose Uptake | Patellar Tendon | Emission Tomography | Exercise Increase | Quadriceps Muscle

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      Department of Orthopedic Surgery, Institute of Sports Medicine, Copenhagen University Hospital - Bispebjerg Frederiksberg, and Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark | Departmen

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