• KOL
    • Skin Cancer
    • Bert Jan Vermeer
    • Bert Jan Vermeer: Influence Statistics

      Bert Jan Vermeer

      Bert Jan Vermeer

      Department of Dermatology, University Hospital Leiden, P.O. Box 9600, 2300 RC Leiden, The Netherlands | Department of Dermatology | Departments of Dermatology University ...

      Is this your profile? manage_accounts Claim your profile content_copy Copy URL code Embed Link to your profile

      Bert Jan Vermeer:Expert Impact

      Concepts for whichBert Jan Vermeerhas direct influence:Skin cancer,Plasma membrane,Renal transplant recipients,Keratotic skin lesions,Solar lentigines,Hla antigens,Cholesterol synthesis,Dna damage.

      Bert Jan Vermeer:KOL impact

      Concepts related to the work of other authors for whichfor which Bert Jan Vermeer has influence:Skin cancer,Basal cell carcinoma,Human papillomavirus,Squamous cell,Transplant recipients,Illness perceptions,Epidermodysplasia verruciformis.

      KOL Resume for Bert Jan Vermeer

      Year
      2006

      Department of Dermatology, University Hospital Leiden, P.O. Box 9600, 2300 RC Leiden, The Netherlands

      2004

      Department of Dermatology

      2001

      Departments of Dermatology University Medical Centre, Leiden, The Netherlands

      2000

      Department of Dermatology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands

      1999

      Department of Dermatology and Clinical Epidemiology, Leiden University Medical Center, The Netherlands

      1998

      Department of Dermatology, Leiden, The Netherlands

      1997

      Department of Dermatology, University Medical Center, Leiden, The Netherlands

      Derinatology

      1996

      Department of Dermatology, University Hospital Leiden, The Netherlands

      Academisch Ziekenhuis, afd. Huidziekten, Leiden.

      1995

      Department of Dermatology, University Hospital Leiden, PO Box 9600, 2300 RC Leiden, the Netherlands

      ICRF Skin Tumour Laboratory, Royal London Hospital, London, United Kingdon

      1994

      From the Department of Dermatology, University Hospital Leiden, Leiden, The Netherlands, and the Department of Dermatology, Sint Franciscus Gasthuis, Rotterdam, The Netherlands.

      Dept Dermatology, University Medical Center, 2333 AA Leiden Netherlands

      Department of Dermatology, University Hospital Leiden, P.O. Box 9600, 2300 RC Leiden

      1993

      Department of Dermatology, Academic Hospital Leiden, The Netherlands

      Brussels, Belgium

      1992

      Department of Dermatology, University Medical Centre, Leiden, The Netherlands

      1991

      Department of Dermatology, University Hospital, Rijnsburgerweg 10, 2333 AA Leiden, The Netherlands

      1990

      Department of Dermatology.

      1988

      Department of Dermatology, State University Hospital, Leiden, The Netherlands

      1987

      Nephrology, Rheumatology, Dermatology, Pathology, and Virology Departments, University Hospital, 2300 RC Leiden, The Netherlands

      Department of Dermatology Service, Veterans Administration Medical Center (SG, BJV), San Francisco, California, U.S.A.

      1986

      Departments of Dermatology and Electron Microscopy, University Medical Centre, Leiden, The Netherlands

      1985

      Departments of Dermatology, University Medical Centre Leiden, The Netherlands

      1984

      aDepartments of Nephrology, University Hospital, Leiden; TNO, Rijswijk, The Netherlands bDepartments of Dermatology, University Hospital, Leiden; TNO, Rijswijk, The Netherlands cDepartments of Pathology, University Hospital, Leiden; TNO, Rijswijk, The Netherlands dDepartments of Institute for Experimental Gerontology, University Hospital, Leiden; TNO, Rijswijk, The Netherlands

      Consultant Dermatologist, Guy's Hospital, London, UK

      Department of Dermatology, University Medical Center

      1983

      Department of Dermatology and Electron Microscopy, University Hospital, 2333 AA Leiden, The Netherlands

      1982

      Department of Dermatology and Electronmicroscopy, University Medical Centre, Leiden, The Netherlands

      1981

      Departments of Dermatology and Immunohaematology, University Medical Centre Leiden, 2333 AA Leiden, Netherlands

      1980

      Gaubius Institute, Health Research Organization TNO, Herenstraat 5d, 2313 AD LeidenThe Netherlands

      1979

      Department of Dermatology, University Medical Centre, Rijnsburgerweg 10, Leiden, The Netherlands

      1978

      Department of Dermatology, Leiden University Medical Centre, Rijnsburgerweg 10, Leiden, The Netherlands

      1977

      Department of Dermatology, University Hospital, Rijnsburgerweg 10, Leiden, The Netherlands

      1976

      Department of Dermatology, University Medical Centre, Rijnsburgerweg 10, LeidenThe Netherlands

      1974

      Departments of Dermatology (Head: Prof. M.K. Polano) and Pediatrics (Head: Prof. G.M.H. Veeneklaas), Leiden University Hospital, Leiden

      Sign-in to see all concepts, it's free!
      Sample of concepts for which Bert Jan Vermeer is among the top experts in the world.
      Concept World rank
      glassfibre paper #1
      tissue ultracryosections #1
      ldlgold #1
      angina pectoris claudication #1
      types melanocytic cells #1
      xanthomas fatty acids #1
      g418 resistance plasmid #1
      65 higher induction #1
      aqueous phase digitonin #1
      gold acldl #1
      ldl male microscopy #1
      xanthomas type #1
      exposed sunscreen #1
      ldl gold #1
      ultrastructural findings lipoproteinsin #1
      normal suprabasal cells #1
      acldl conjugated #1
      disease ligandreceptor interactions #1
      permitted demonstration presence #1
      ° ldl #1
      betaeimmunoreactivity #1
      tyrosinase 3t3 #1
      gammaendorphin basis #1
      smoothwalled endosomes #1
      usual melanosome ontogenesis #1
      exfoliative diltiazem #1
      free cholesterol cholesterolesters #1
      endocytosis gamma endorphin #1
      uvb protocol #1
      osmium cholesterol #1
      erythema uv meter #1
      betaeir #1
      83436 #1
      expression alpha beta #1
      phospholipids xanthomas #1
      keratinocytes predictions #1
      melanogenesis transfected fibroblasts #1
      17 xanthomatous lesions #1
      ldl electron receptors #1
      atypical naevus cells #1
      risk estimates melanocytes #1
      normal melanosome biogenesis #1
      fixatives retention #1
      Sign-in to see all concepts, it's free!

      Prominent publications by Bert Jan Vermeer

      KOL-Index: 18858

      BACKGROUND: Recipients of renal allografts are at an increased risk for skin cancer. It is also known that recipients who are homozygous for HLA antigens are at an increased risk for certain cancers, as are those who are mismatched with their donors for these antigens. In a case-control study we assessed the relation between skin cancer in renal-transplant recipients and HLA homozygosity and mismatching.

      METHODS: Of 764 patients who received renal transplants between 1966 and 1988, 66 ...

      Known for Hla Antigens | Skin Cancer | Transplant Recipients | Basal Cell Carcinoma | Exposure Sunlight
      KOL-Index: 15124

      Melanocortin-1 receptor (MC1R) gene variants are associated with fair skin and red hair and, independently of these, with cutaneous malignant melanoma. The association of MC1R gene variants with nonmelanoma skin cancer is largely unknown. A total of 838 subjects were included in the present study: 453 patients with nonmelanoma skin cancer and 385 subjects with no skin cancer. The coding sequence of the human MC1R gene was tested using single-stranded conformation polymorphism analysis ...

      Known for Fair Skin | Gene Variants | Corticotropin Receptors | Variant Alleles | Risk Carriers
      KOL-Index: 14878

      The regulation of cholesterol synthesis in cultured human skin fibroblasts and keratinocytes was compared, the incorporation of [14C]-acetate or [14C]-octanoate into [14C]-cholesterol being taken as a measure of de novo cholesterol synthesis. The two types of cultured cells differed in the following features of the regulation of cholesterol synthesis: (1) Keratinocytes synthesized 10-fold more cholesterol/mg cell protein. (2) Keratinocytes retained a greater amount of the de novo ...

      Known for Cholesterol Synthesis | Skin Fibroblasts | Ldl Keratinocytes | Cultured Human | Culture Medium
      KOL-Index: 12511

      DNA of the epidermodysplasia-verruciformis associated subgroup of HPV (EV-HPV) is frequently detected in biopsies of premalignant lesions and nonmelanoma skin cancers of renal transplant recipients. The prevalence of EV-HPVs, however, has never been systematically studied in benign keratotic skin lesions of patients with or without a history of skin cancer. This study included 42 renal transplant recipients with and 36 without a history of skin cancer. A total of 176 skin biopsies were ...

      Known for Skin Cancer | Renal Transplant | Human Papillomavirus Dna | Premalignant Lesions | Epidermodysplasia Verruciformis
      KOL-Index: 12134

      The association between human papillomavirus (HPV)-associated cervical cancer and cutaneous squamous cell carcinoma and codon 72 polymorphism in the p53 gene is not unequivocal. Especially, it is not known whether carriers of the arginine form have an increased risk of cancer that necessitates screening. The alternative is that the polymorphism is a tumor marker instead of a risk factor. We set out a case-control study to determine the risk of squamous cell carcinoma of the skin in ...

      Known for Cell Carcinoma | P53 Codon | 72 Polymorphism | Cutaneous Squamous | Human Papillomavirus
      KOL-Index: 11877

      In a retrospective follow-up study, 36 renal transplant recipients with, and 101 without, skin cancer, who had received their first transplant before January 1981 and who were still alive with a functioning graft on 1 August 1989, were assessed to determine the risk of non-melanoma skin cancer in relation to exposure to sunlight during childhood and adolescence. The contribution of the number of keratotic skin lesions to the skin cancer risk was also assessed. The estimated relative ...

      Known for Skin Cancer | Exposure Sunlight | Renal Transplant | Basal Cell Carcinoma | Odds Ratios
      KOL-Index: 11665

      An immunoelectron-microscopic technique was applied to investigate the localization of molecules that are involved in the elicitation of allergic contact dermatitis in human epidermal cells in situ. Langerhans cells in the epidermis of lesions showed a strongly increased cell surface expression of HLA class II molecules as compared with normal skin. In addition, a high number of intracellularly located HLA class II molecules were present in Langerhans cells of lesional epidermis, ...

      Known for Langerhans Cells | Hla Class | Allergic Contact Dermatitis | Birbeck Granules | Human Epidermal
      KOL-Index: 11474

      Solar lentigines and ephelides are different types of pigmented skin lesions predominantly present on sun-exposed skin. Both lesions are risk indicators for melanoma and non-melanoma skin cancer. Solar lentigines are considered as a sign of photodamage although well-conducted epidemiological studies are lacking on this subject. Ephelides are associated with fair skin type and red hair. The aim of the present study was to investigate the relation of sun-exposure estimates with solar ...

      Known for Solar Lentigines | Sun Exposure | Skin Type | Contrast Ephelides | Lentigo Male
      KOL-Index: 11392

      Ultraviolet-B (UVB, 280-320 nm) radiation can promote the induction of skin cancer by two mechanisms: damage of epidermal DNA and suppression of the immune system, allowing the developing tumor to escape immune surveillance. The mixed lymphocyte reaction (MLR) and the mixed epidermal cell lymphocyte reaction (MECLR) are commonly used methods to study the immunosuppressive effects of UVB radiation. To obtain a better understanding of the mechanism by which UVB radiation decreases the ...

      Known for Action Spectra | Dna Damage | Mlr Meclr | 254 Nm | Epidermal Cells
      KOL-Index: 11304

      Unlike cells cultured under physiological Ca2+ concentrations (1-2 mM), keratinocytes cultured in media containing Ca2+ in low concentrations (less than 0.1 mM) do not stratify. The latter cells also differ with respect to several features of the regulation of cholesterol synthesis. In keratinocytes cultured in medium containing high Ca2+ concentrations (1.6 mM) and fetal calf serum, the rate of cholesterol synthesis was 20-30 times higher than in keratinocytes exposed to a low Ca2+ ...

      Known for Cholesterol Synthesis | Human Epidermal Keratinocytes | Low Density Lipoprotein | Electron Receptors | Epidermal Cells
      KOL-Index: 11055

      Exposure of mice or humans to solar or artificial ultraviolet radiation (UV) has been shown to induce a number of changes in the immune system that may influence their susceptibility to skin tumors. The protective effect of sunscreens on these changes is not clear. Thirty-two patients with a variety of dermatoses routinely undergoing treatment with standard UVB (n = 19) or PUVA (n = 13) therapy were studied. One of the two tested sunscreens or its vehicle was applied to the right flexor ...

      Known for Alloactivating Capacity | Human Skin | Induced Suppression | Sunscreens Uv | 4 Weeks
      KOL-Index: 10923

      Based on immunologic and epidemiologic data, it is plausible that skin cancer in renal transplant recipients is associated with human papillomaviruses (HPV). At present, conflicting evidence exists concerning the presence of HPV DNA in these cancers. We recently described a nested polymerase chain reaction method that enables the detection of all previously isolated epidermodysplasia verruciformis (EV)-associated HPVs. We now describe the detection of EV-associated HPV DNA in 49 (80%) of ...

      Known for Epidermodysplasia Verruciformis | Renal Transplant Recipients | Hpv Dna | Premalignant Skin | Human Papillomaviruses
      KOL-Index: 10591

      Interleukin-1 alpha (IL-1 alpha) and tumor necrosis factor-alpha (TNF-alpha) induce a motogenic response in a number of benign and malignant cells. We examined the chemokinetic effects of these cytokines on the cell migration of four melanoma cell lines on fibronectin using modified Boyden chambers and video-time lapse analysis. Flow cytometry analysis of IL-1 receptors, TNF receptors, and shifts in beta 1 integrin expression were correlated with the effects of these cytokines on cell ...

      Known for Melanoma Cell | Tumor Necrosis | Tnf Alpha | Integrin Expression | Migration Fibronectin

      Key People For Skin Cancer

      Top KOLs in the world
      #1
      Martin A Weinstock
      united states skin cancer indoor tanning
      #2
      Adèle C Green
      ovarian cancer sun exposure cutaneous melanoma
      #3
      Alan C Geller
      skin cancer united states medical students
      #4
      Bruce Konrad Armstrong
      sun exposure western australia new south wales
      #5
      Allan C Halpern
      skin cancer dysplastic nevi united states
      #6
      Steven Richard Feldman
      united states atopic dermatitis psoriasis patients

      Department of Dermatology, University Hospital Leiden, P.O. Box 9600, 2300 RC Leiden, The Netherlands | Department of Dermatology | Departments of Dermatology University Medical Centre, Leiden, The Netherlands | Departments of Dermatology and | Depar

    Download on the App StoreGet it on Google Play

    Copyright © 2023 Key Opinion Leaders, LLC.