Bedrich ROTH

Seventy patients suffering from narcolepsy and eighteen patients with hypersomnia were examined by polygraphic methods. A total of 115 recordings were made.In patients suffering exclusively from narcoleptic attacks only signs of NREM sleep were found. The findings were similar, with one single exception, in patients with hypersomnia.In the group of patients suffering from narcolepsy with cataplexy or sleep paralysis, sleep onset REM periods were noticed in 47.1% of all records. Signs of ...

A questionnaire survey has been made of the life effects of narcolepsy in 180 patients, 60 each from North American, Asian and European populations, with 180 similarly distributed age and sex matched controls. Life-effects were attributed by the patients to the primary symptoms of excessive daytime drowsiness, sleep attacks, cataplexy, vivid hypnagogic hallucinations and sleep paralysis, and also to other frequent symptoms such as visual problems (blurring, diplopia) and memory ...

A recent questionnaire survey of the life-effects of narcolepsy in 180 patients, 60 each from North American, Asian and European populations, compared to similarly distributed age and sex matched controls, documented multiple and marked effects on work, education, driving, accidents, recreation, personality, memory and other parameters. The data have now been further analysed according to the patients' geographic (culturo-genetic) origin and to a number of other patient and illness ...

1.1. States of lowered vigilance are characterized by EEG rhythms corresponding to the period of transition from awakeness to sleeping. Their appearance in the EEG may, however, be infraclinical.2.2. The author distinguishes four stages of reduced vigilance and describes their morphological appearance, dynamics, reactibility to external stimulation and responses to methods of activation.3.3. Signs of lowered vigilance are most common in narcolepsy and hypersomnia, in organic diseases of ...

The correlation of clinical and EEG findings was studied in 40 patients with Wilson's disease and their 57 heterozygous relations (25 children, 30 parents and 2 siblings). EEG changes in Wilson's disease were found in 84% (50% mild, 34% moderate) with but a slight predominance in patients with neurological involvement. The relatively high rate of pathological EEG findings in the hepatic or asymptomatic forms suggested the presence of subclinical CNS damage even in these cases. Diffuse ...

In the course of polygraphic studies of night sleep the authors recorded respiration through the right and left nostrils by means of two thermoelements. They observed a peculiar and unexpected phenomenon: during the REM sleep phase of the 3rd sleep cycle of 4 healthy persons with 6 full night recordings, respiration through the left nostril stopped, whereas it increased both in frequency and amplitude through the right nostril. This type of respiration continued until awakening. In 2 ...