Eric A Hoffman: Influence Statistics

Eric A Hoffman

Eric A Hoffman

Walter Schottky Institut & Physik Department, Technische Universität München, D-85748, Garching, Germany | Institute for Advanced Study, Technische Universität München, ...

Eric A Hoffman: Expert Impact

Concepts for which Eric A Hoffman has direct influence: Childhood asthma , Lung function , Pulmonary disease , Copdgene study , Chronic obstructive , Copd study , Subjects prism .

Eric A Hoffman: KOL impact

Concepts related to the work of other authors for which for which Eric A Hoffman has influence: Lung function , Chronic obstructive , Pulmonary disease , Copd risk , Low fvc , Preserved ratio , Ecological connectivity .

KOL Resume for Eric A Hoffman


Walter Schottky Institut & Physik Department, Technische Universität München, D-85748, Garching, Germany


University of Central Florida Department of Biology Orlando FL


Kaman Science Corp. (USA)

Prominent publications by Eric A Hoffman

KOL-Index: 12319 . RATIONALE: Increasing awareness of the prevalence and significance of Preserved Ratio Impaired Spirometry (PRISm), alternatively known as restrictive or Global Initiative for Chronic Obstructive Lung Disease (GOLD)-unclassified spirometry, has expanded the body of knowledge on cross-sectional risk factors. However, longitudinal studies of PRISm remain limited. OBJECTIVES: To examine ...
Known for Subjects Prism | Copdgene Study | Lung Function | Fev1 Fvc
KOL-Index: 11768 . BACKGROUND: Childhood asthma is strongly influenced by genetics and is a risk factor for reduced lung function and chronic obstructive pulmonary disease (COPD) in adults. This study investigates self-reported childhood asthma in adult smokers from the COPDGene Study. We hypothesize that childhood asthma is associated with decreased lung function, increased risk for COPD, and that a ...
Known for Childhood Asthma | Lung Function | Risk Copd | Genome Wide
KOL-Index: 7771 . BACKGROUND: The relationship between 25-hydroxyvitamin D (25-OH-vitamin D) and COPD outcomes remains unclear. Using the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS), we determined associations among baseline 25-OH-vitamin D and cross-sectional and longitudinal lung function and COPD exacerbations. METHODS: Serum 25-OH-vitamin D level was measured in stored ...
Known for Lung Function | Vitamin Deficiency | Year 95 | Fev1 Decline
KOL-Index: 6000 . BACKGROUND: Aspirin use in COPD has been associated with reduced all-cause mortality in meta-regression analysis with few equivocal studies. However, the effect of aspirin on COPD morbidity is unknown. METHODS: Self-reported daily aspirin use was obtained at baseline from SPIROMICS participants with COPD (FEV1/FVC < 70%). Acute exacerbations of COPD (AECOPD) were prospectively ascertained ...
Known for Aspirin Copd | Acute Exacerbations | Intermediate Outcome | Pulmonary Disease
KOL-Index: 4083 . Amphibian biology is intricate, and there are many inter-related factors that need to be understood before establishing successful Conservation Breeding Programs (CBPs). Nutritional needs of amphibians are highly integrated with disease and their husbandry needs, and the diversity of developmental stages, natural habitats, and feeding strategies result in many different recommendations for ...
Known for Amphibian Husbandry | Natural Habitats | Animal Nutritional | Physiological Phenomena
KOL-Index: 2969 . Genome-wide association studies (GWAS) have identified multiple associations with emphysema apicobasal distribution (EABD), but the biological functions of these variants are unknown. To characterize the functions of EABD-associated variants, we integrated GWAS results with 1) expression quantitative trait loci (eQTL) from the Genotype Tissue Expression (GTEx) project and subjects in the ...
Known for Genetic Epidemiology | Genome Wide | Expression Lung | Functional Variant
KOL-Index: 2413 . BACKGROUND: The large airway epithelial barrier provides one of the first lines of defense against respiratory viruses, including SARS-CoV-2 that causes COVID-19. Substantial inter-individual variability in individual disease courses is hypothesized to be partially mediated by the differential regulation of the genes that interact with the SARS-CoV-2 virus or are involved in the subsequent ...
Known for Gene Expression | Cov2 Covid19 | Airway Epithelium | Factors Sars
KOL-Index: 2191 . Nanowires (NWs) are ideal nanostructures for exploring the effects of low dimensionality and thermal conductivity suppression on thermoelectric behavior. However, it is challenging to accurately measure temperature gradients and heat flow in such systems. Here, using a combination of spatially resolved Raman spectroscopy and transport measurements, we determine all the thermoelectric ...
Known for Insb Nanowires | Merit Zt | Transport Measurements | Measured Thermoelectric
KOL-Index: 1868
Known for Perna Viridis | Megabalanus Coccopoma | Mytella Charruana | Southeastern Usa
KOL-Index: 1196 . BACKGROUND: Pulmonary and systemic inflammation are central features of chronic obstructive pulmonary disease (COPD). Previous studies have demonstrated relationships between biologically active extracellular matrix components, or matrikines, and COPD pathogenesis. We studied the relationships between the matrikine acetyl-proline-glycine-proline (AcPGP) in sputum and plasma and clinical ...
Known for Pulmonary Disease | Plasma Samples | Chronic Obstructive | Airflow Limitation
KOL-Index: 858 . Rationale: Multiple studies have demonstrated an increased risk of chronic obstructive pulmonary disease (COPD) in heterozygous carriers of the AAT (alpha-1 antitrypsin) Z allele. However, it is not known if MZ subjects with COPD are phenotypically different from noncarriers (MM genotype) with COPD. Objectives: To assess if MZ subjects with COPD have different clinical features compared ...
Known for Pulmonary Disease | 1 Antitrypsin | Chronic Obstructive
KOL-Index: 731 . Rationale: The ability of peripheral blood biomarkers to assess chronic obstructive pulmonary disease (COPD) risk and progression is unknown. Genetics and gene expression may capture important aspects of COPD-related biology that predict disease activity. Objectives: Develop a transcriptional risk score (TRS) for COPD and assess the contribution of the TRS and a polygenic risk score (PRS) ...
Known for Obstructive Pulmonary | Disease Chronic
KOL-Index: 706 . BACKGROUND: Improved understanding of the pathways associated with airway pathophysiologic features in COPD will identify new predictive biomarkers and novel therapeutic targets. RESEARCH QUESTION: Which physiologic pathways are altered in the airways of patients with COPD and will predict exacerbations? STUDY DESIGN AND METHODS: We applied a mass spectrometric panel of metabolomic ...
Known for Adenosine Metabolism | Biomarkers Therapeutic

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Walter Schottky Institut & Physik Department, Technische Universität München, D-85748, Garching, Germany | Institute for Advanced Study, Technische Universität München, D-85748, Garching, Germany | University of Central Florida Department of Biology