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  • Emergency Department
  • William J Lewander

    Prominent publications by William J Lewander

    KOL Index score: 10021

    STUDY OBJECTIVE: To determine whether Gram stain of urine is more sensitive than urinalysis in detecting urinary tract infection in infants.

    DESIGN: Prospective series.

    SETTING: Urban teaching hospital emergency department.

    PARTICIPANTS: Two hundred seven infants 6 months old or less, from whom a catheterized or suprapubically aspirated urine specimen was obtained for culture.

    INTERVENTIONS: Urinary Gram stain, culture, and urinalysis were performed. With culture results as the ...

    Also Ranks for: Gram Stain |  urinary tract infection |  culture urinalysis |  leukocyte esterase |  sensitivity specificity
    KOL Index score: 8183

    Previous work in our laboratory has demonstrated that sodium polystyrene sulfonate (SPS) significantly lowered serum lithium (Li) concentrations when administered in a single oral dose after an oral dose of lithium in a mouse model. The present study was designed to determine whether: 1) repetitive doses of SPS are effective in lowering serum lithium concentrations, 2) the effect of SPS on lithium concentration is dose related and 3) SPS enhances the elimination of lithium. Mice (N = ...

    Also Ranks for: Sodium Polystyrene Sulfonate |  lithium intoxication |  licl sps |  5 dose |  statistical analyses
    KOL Index score: 8121

    OBJECTIVE: The purpose of this study was to examine alcohol use, alcohol-related problems, other risk-taking behaviors, and parental monitoring in adolescents who tested positive for alcohol in an emergency department.

    STUDY DESIGN: A matched case-control design was implemented for adolescents presenting to a pediatric emergency department who were screened for alcohol use. An alcohol-positive sample (N = 150) was compared with a matched alcohol-negative sample (N = 150) for alcohol use, ...

    Also Ranks for: Emergency Department |  adolescents alcohol |  parental monitoring |  risktaking behaviors |  case control
    KOL Index score: 8092

    OBJECTIVES: To determine the efficacy of sodium polystyrene sulfonate (SPS) in lowering serum lithium (Li) concentrations. Specifically, to determine the effects of both different doses of SPS and different times to treatment with SPS on serum Li levels.

    METHODS: The study was a controlled, single-dose murine trial of SPS on serum Li levels. Male CD-1 mice (n = 525) were given orogastric LiCl and then divided into three main treatment groups: group SPS received a single orogastric ...

    Also Ranks for: Sodium Polystyrene Sulfonate |  serum lithium |  sps treatment |  concentrations mice |  cation exchange
    KOL Index score: 7884

    The benefit of beta-adrenergic agonists in the treatment of acutely wheezing infants and young children has not been well documented in the outpatient setting. To determine the efficacy of nebulized metaproterenol sulfate, 74 children aged 36 months or younger with acute wheezing participated in a double-masked, randomized, placebo-controlled clinical trial. Children received nebulized metaproterenol, either as an initial treatment or after a control treatment with normal saline ...

    Also Ranks for: Respiratory Rate |  wheezing infants |  oxygen saturation |  young children |  syncytial virus
    KOL Index score: 7042

    Empirical data to help gauge risk for repeat suicide attempts and noncompliance with outpatient psychiatric care among adolescent suicide attempters discharged from emergency departments is scarce. In this study, 62 adolescent suicide attempters discharged from a regional trauma center serving an urban/suburban area with a broad range of social classes were followed up at three months after their attempts to assess treatment compliance and repeat attempts. Information regarding suicidal ...

    Also Ranks for: Suicide Attempt |  treatment compliance |  emergency department |  suicidal intent |  service hospital
    KOL Index score: 7041

    OBJECTIVE: To determine whether a problem-solving intervention would increase adherence to outpatient treatment for adolescents after a suicide attempt.

    METHOD: Sixty-three adolescents who had attempted suicide and were evaluated in an emergency department between 1997 and 2000 were randomly assigned to undergo standard disposition planning or a compliance enhancement intervention using a problem-solving format. At 3 months after the intervention, all evaluable adolescents, guardians, ...

    Also Ranks for: Suicide Attempt |  outpatient treatment |  emergency department |  problem solving |  compliance enhancement
    KOL Index score: 6897

    OBJECTIVES: The objective was to determine if adolescents presenting to a pediatric emergency department (PED) for an alcohol-related event requiring medical care differ in terms of substance use, behavioral and mental health problems, peer relationships, and parental monitoring based on their history of marijuana use.

    METHODS: This was a cross-sectional comparison of adolescents 13-17 years old, with evidence of recent alcohol use, presenting to a PED with a self-reported history of ...

    Also Ranks for: Alcohol Marijuana |  department patients |  substance adolescents |  binge drinking |  adolescent behavior
    KOL Index score: 6782

    OBJECTIVE: To determine whether a brief individual motivational interview (IMI) plus a family motivational interview (Family Check-Up [FCU]) would reduce alcohol use in adolescents treated in an emergency department after an alcohol-related event more effectively than would an IMI only.

    DESIGN: Two-group randomized design with 3 follow-up time points.

    SETTING: An urban regional level I trauma center.

    PARTICIPANTS: Adolescents aged 13 to 17 years (N = 125) with a positive blood alcohol ...

    Also Ranks for: Emergency Department |  motivational interventions |  alcohol drinking |  adolescents treated |  clinical trial
    KOL Index score: 6605

    We tested whether a brief motivational interview (MI) would reduce alcohol-related consequences and use among adolescents treated in an emergency department (ED) after an alcohol-related event. Patients aged 13 to 17 years (N = 152) with a positive blood alcohol concentration (BAC) by lab test or self-report were recruited in the ED and randomly assigned to receive either MI or standard care (SC). Both conditions resulted in reduced quantity of drinking during the 12-month follow-up, ...

    Also Ranks for: Emergency Department |  positive adolescents |  randomized clinical trial |  alcoholrelated event |  alcohol drinking
    KOL Index score: 6116

    This study evaluated the efficacy of using a brief motivational intervention to reduce smoking among adolescent patients treated in a hospital outpatient clinic or Emergency Department. Patients aged 14-19 years (N=85) were randomly assigned to receive either one session of motivational interviewing (MI) or standardized brief advice (BA) to quit smoking. The assessment and intervention were conducted in the medical setting proximal to the patient's medical treatment. Patients were ...

    Also Ranks for: Motivational Intervention |  adolescent smokers |  medical settings |  6 months |  1 month
    KOL Index score: 5837

    To determine whether sodium polystyrene sulfonate (SPS; Kayexalate) is effective in decreasing the absorption of lithium (Li) and to test the assumption that Li is poorly adsorbed by activated charcoal, 130 mice were administered an orogastric dose of LiCl (250 mg/kg) followed immediately by orogastric SPS (10 g/kg, SPS Group), activated charcoal (6.7 g/kg, AC Group), or water in an equivalent volume (Control Group). Subgroups of each of the 3 groups were sacrificed at 1, 2, 4 and 8 hr ...

    Also Ranks for: Activated Charcoal |  lithium intoxication |  sodium polystyrene sulfonate |  serum concentrations |  orogastric sps
    KOL Index score: 5663

    OBJECTIVE: To determine the factors associated with physician decisions to test for alcohol involvement in adolescents treated in an emergency department (ED) and to examine patient and event characteristics associated with being identified as alcohol positive, either by testing or by clinical examination.

    METHODS: Medical chart reviews were conducted for all adolescent patients (n = 9,660; age range, 13-19 y) treated over a 1-year period in a Level I regional trauma center/ED.

    RESULTS: ...

    Also Ranks for: Alcohol Involvement |  emergency department |  adolescent patients |  universal screening |  wounds injuries


    William J Lewander: Influence Statistics

    Sample of concepts for which William J Lewander is among the top experts in the world.
    Concept World rank
    single dose sps #1
    90 minutes licl #1
    treatment groups sps #1
    orogastric sps #1
    naloxone antidotes #1
    licl sps #1
    ivadministered lithium #1
    lithium elimination #1
    statistical analyses sps #1
    sps dose #1
    licl experimental #1
    lithium toxicity effects #1
    packet ingestion #1
    single orogastric #1
    single doses sps #1
    administration sps #1
    acute thyroxine #1
    6hour time points #1
    sps elimination #1
    parenteral lithium #1
    ability serum concentrations #1
    urinary gram stain #1
    multiple doses sps #1
    licl sps treatment #1
    multiple‐dose sodium #1
    minutes licl #1
    sps licl #1
    ipecac 2 #1
    doses sps #1
    received sps #1
    sps serum concentrations #1
    licl normal saline #1
    lithium vitro techniques #1
    strains polystyrenes #1
    orogastric licl #1
    urinary gram #1
    210 minutes licl #1
    kayexalate sps #1
    administration licl #1
    sps received #1
    shortterm adolescent drinking #2
    alcoholpositive teens #2
    oral dose lithium #2

    Key People For Emergency Department

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    William J Lewander:Expert Impact

    Concepts for whichWilliam J Lewanderhas direct influence:Emergency department,  Sodium polystyrene sulfonate,  Adolescent patients,  Adolescent suicide attempters,  Alcohol involvement,  Adolescent suicide,  Isopropyl alcohol,  Lithium intoxication.

    William J Lewander:KOL impact

    Concepts related to the work of other authors for whichfor which William J Lewander has influence:Emergency department,  Motivational interviewing,  Young people,  Methylene blue,  Smoking cessation,  Energy drinks,  Child abuse.



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    Departments of Emergency Medicine and Pediatrics, The Alpert Medical School of Brown University. | Hasbro Children's Hospital, 593 Eddy Street, Providence, RI 02903, United States | Warren Alpert Medical School, Brown University, Providence, RI 02912