• Disease
  • Synovial
  • Synovial Sarcoma
  • Franz M Enzinger

    Prominent publications by Franz M Enzinger

    KOL Index score: 12349

    The tumor described here as lipofibromatosis is a rare pediatric neoplasm that has been variously interpreted as a type of infantile or juvenile fibromatosis, a variant of fibrous hamartoma of infancy, and a fibrosing lipoblastoma. This report details the clinicopathologic features associated with 45 cases of this soft tissue entity. The study group consisted of 32 males, 12 females, and one person of unstated gender. The patients presented with a soft tissue mass (range, 1-7 cm) ...

    Also Ranks for: Adipose Tissue |  clinicopathologic study |  fibroblastic elements |  fibrous hamartoma |  preschool diagnosis
    KOL Index score: 9991

    We report 25 cases of a peculiar sclerosing epithelioid variant of fibrosarcoma (SEF) simulating an infiltrating carcinoma. The tumors occurred primarily in the deep musculature and were frequently associated with the adjacent fascia or periosteum. The patients' ages were 14 to 87 years (median, 45). Fourteen were male and 11 female. The tumors were located in the lower extremities and limb girdles (12 cases), trunk (9), upper limb girdles (2), and neck (2). They measured 2 to 14.5 cm in ...

    Also Ranks for: Sclerosing Epithelioid |  tumor cells |  fibrosarcoma sef |  disease followup |  limb girdles
    KOL Index score: 9542

    It has been generally recognized that malignant fibrous histiocytoma (MFH) may assume a highly myxoid, hypocellular appearance. Eighty cases of malignant fibrous histiocytoma having varying degrees of myxoid change were reviewed. These tumors typically arose on the extremities (leg, 61%; arm, 21%) of adults (peak age incidence, 60-69 years). They were usually attached to fascia (31%) or involved skeletal muscle (51%) and had a mucoid or translucent appearance. The myxoid areas consisted ...

    Also Ranks for: Myxoid Variant |  malignant fibrous histiocytoma |  rate metastasis |  benign fibrous humans |  cellular areas
    KOL Index score: 9444

    Epithelioid hemangioendothelioma is a unique tumor of adult life which is characterized by an "epithelioid" or "histiocytoid" endothelial cell. Forty-one cases of this rare tumor have been recognized at the Armed Forces Institute of Pathology. They may occur in either superficial or deep soft tissue, and in 26 cases appeared to arise from a vessel, usually a medium-sized or large vein. They are composed of rounded or slightly spindled eosinophilic endothelial cells with rounded nuclei ...

    Also Ranks for: Vascular Tumor |  epithelioid hemangioendothelioma |  metastatic carcinoma |  ultrastructural study |  mitotic activity
    KOL Index score: 8035

    We studied the clinical and pathologic features of 78 malignant peripheral nerve sheath tumors in children less than or equal to 15 years of age. There were 42 boys and 36 girls, with a median age of 10 years. The majority of the tumors (42, or 54%) were central or axial in location; the rest were peripheral. Sixteen patients (21%) had a history of von Recklinghausen's disease. Fourteen (18%) had a malignant peripheral nerve sheath tumor arising in a nerve trunk or a neurofibroma and ...

    Also Ranks for: Peripheral Nerve |  sheath tumor |  recklinghausens disease |  malignant schwannomas |  7 years
    KOL Index score: 7886

    The clinicopathologic findings in 200 cases of malignant fibrous histiocytoma (MFH) with follow-up information are presented. This tumor occurred principally as a mass on an extremity (lower extremity 49%, upper extremity 19%) or in the abdominal cavity or retroperitoneum (16%) of adults (peak incidence 61-70 years of age). It typically involved deep fascia (19%) or skeletal muscle (59%) and only rarely was confined to the subcutis without fascial involvement (7%). The MFH had variable ...

    Also Ranks for: Malignant Fibrous Histiocytoma |  metastasis mfh |  preschool diagnosis |  tumor tumors |  lymph nodes
    KOL Index score: 7461

    A series of 46 malignant schwannomas occurring in soft parts of patients having von Recklinghausen's neurofibromatosis was analyzed. The diagnosis of malignant schwannoma was based upon the occurrence of malignant spindled cells closely resembling Schwann cells in the neoplasm and the close association or origin of the malignant schwannoma in a neurofibroma (27 tumors), or a large peripheral nerve (31 tumors). Additional histologic features useful in making the diagnosis of malignant ...

    Also Ranks for: Malignant Schwannoma |  patients diagnosis |  schwann cells |  lower extremity |  nuclear palisading
    KOL Index score: 7343

    A series of 106 cases of hemangiopericytoma was analyzed. The neoplasms occurred principally in adults (median age, 45 years), were deep seated, and were most common in the thigh (27 cases) and the pelvic retroperitoneum (26 cases). A painless mass was the first symptom in 96 of the patients. The median size of the excised tumors was 6.5 cm. Surgical removal of the tumor was often complicated by hemorrhage because of marked dilatation of the vascular bed in the vicinity of the neoplasm, ...

    Also Ranks for: Recurrence Metastasis |  hemangiopericytoma humans |  preschool diagnosis |  tumor hemorrhage |  surgical removal
    KOL Index score: 7279

    The malignant giant cell tumor of soft parts is an extraskeletal malignant neoplasm somewhat resembling a giant cell tumor of bone and consisting of multinucleated giant cells (occasionally containing asteroid bodies), monon-nuclear histiocytes, and fibroblasts arranged in a multinodular pattern. Thirty-two cases of this tumor in the AFIP files were reviewed and subdivided into a superficial and a deep group; the superficial tumors (12 cases) were small and occurred in the region of the ...

    Also Ranks for: Soft Parts |  cell tumor |  malignant giant |  32 cases |  superficial fascia

    Fibroma of tendon sheath

    KOL Index score: 7170

    The clinical and pathological features of 138 cases of fibroma of tendon sheath are presented. The tumor predominated between the 3rd and 5th decades; the youngest patient was 5 months of age, the oldest 70 years (median 31 years). The tumor was more common in males (75%) than in females; it affected chiefly the tendons and tendon sheaths of the fingers (49%), hands (21%), and wrist (12%). The main presenting symptom was an insidiously growing mass causing mild tenderness or pain in ...

    Also Ranks for: Tendon Sheath |  fingers hands |  nodular fasciitis |  fibrous histiocytoma |  6 years


    Franz M Enzinger: Influence Statistics

    Sample of concepts for which Franz M Enzinger is among the top experts in the world.
    Concept World rank
    type female histiocytoma #1
    adult liposarcoma #1
    synovial sarcoma 2551 #1
    degree myxoid #1
    filaments neoplasm #1
    absence antialpha1antitrypsin #1
    keratin desmin types #1
    dermatofibrosarcoma clinicopathologic analysis #1
    lesions myositis ossificans #1
    mildly atypical nuclei #1
    males 19 cases #1
    fibrosarcoma follow #1
    revealed benign #1
    largevessel type #1
    benign tuberous xanthoma #1
    distinctive sinusoidlike spaces #1
    53 cases prs #1
    decubital fibroplasia diagnosis #1
    finely divided chromatin #1
    hemangiopericytoma analysis #1
    hemangioma hemangiosarcoma humans #1
    106 cases hemangiopericytoma #1
    resembling ewing #1
    nerve macrodactyly #1
    tumors 25 necrosis #1
    proliferative fasciitis #1
    plexiform capillary pattern #1
    majority retroperitoneum #1
    53 cases lesion #1
    hemangiosarcoma breast #1
    elements malignant tumor #1
    diffuse type tumor #1
    mfh myxoid #1
    histiocytoma age #1
    thigh chiefly #1
    tumor soft tissues #1
    reaction simulating #1
    liposarcoma adults #1
    shoulder posterior neck #1
    29year age #1
    differential extremities #1
    orthovoltage radiation patients #1

    Key People For Synovial Sarcoma

    Top KOLs in the world
    Cyril FISHER†
    soft tissue synovial sarcoma situ hybridization
    Marc Ladanyi
    acquired resistance lung cancer synovial sarcoma
    Cristina R Antonescu
    situ hybridization soft tissue gastrointestinal stromal
    Murray, F Brennan
    gastric cancer soft tissue pancreatic adenocarcinoma
    James M Woodruff
    synovial sarcoma soft tissue 5 years
    Janet M Shipley
    germ cell situ hybridization alveolar rhabdomyosarcoma

    Franz M Enzinger:Expert Impact

    Concepts for whichFranz M Enzingerhas direct influence:Synovial sarcoma,  Soft tissue,  Malignant fibrous histiocytoma,  Proliferative fasciitis,  Soft parts,  Preschool diagnosis,  Myxoid variant,  Proliferative myositis.

    Franz M Enzinger:KOL impact

    Concepts related to the work of other authors for whichfor which Franz M Enzinger has influence:Soft tissue,  Malignant fibrous histiocytoma,  Epithelioid sarcoma,  Differential diagnosis,  Tumor cells,  Situ hybridization,  Infantile myofibromatosis.



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    From the Department of Soft Tissue Pathology (J.F.F., M.M., F.M.E.), Armed Forces Institute of Pathology, Washington, DC, U.S.A.; the Department of Pathology (W.B.L.), Northwestern University Medical Center, Chicago, Illinois, U.S.A.; and the Departm