• Disease
  • Pain
  • Pain Disorder
  • Shinpei Yoshimura

    Prominent publications by Shinpei Yoshimura

    KOL Index score: 11685

    BACKGROUND: Depression is characterized by enhanced self-referential processing of negative emotional stimuli. Imaging studies have suggested that activation of both the medial prefrontal (MPFC) and anterior cingulate cortices (ACC) is associated with self-referential processing. However, whether this pattern of activation occurs in depressed individuals during the self-referential processing of the emotional stimuli had not been investigated to date.

    METHODS: Participants were 13 ...

    Also Ranks for: Depressive Symptoms |  medial prefrontal |  rostral acc |  selfreferential processing |  cortex activity
    KOL Index score: 10813

    Cognitive behavioral therapy (CBT), an effective treatment for depression, targets self-referential processing of emotional stimuli. We examined the effects of CBT on brain functioning during self-referential processing in depressive patients using functional magnetic resonance imaging (fMRI). Depressive patients (n = 23) and healthy participants (n = 15) underwent fMRI scans during a self-referential task using emotional trait words. The depressive patients had fMRI scans before and ...

    Also Ranks for: Cognitive Behavioral Therapy |  selfreferential processing |  depressive patients |  cbt depression |  anterior cingulate
    KOL Index score: 9232

    BACKGROUND: A recent meta-analysis of many magnetic resonance imaging (MRI) studies has identified brain regions with gray matter (GM) abnormalities in patients with major depressive disorder (MDD). A few studies addressing GM abnormalities in patients with treatment-resistant depression (TRD) have yielded inconsistent results. Moreover, although TRD patients tend to exhibit ruminative thoughts, it remains unclear whether rumination is related to GM abnormalities in such patients or ...

    Also Ranks for: Gray Matter |  major depression |  magnetic resonance |  trd patients |  brain regions
    KOL Index score: 8053

    Neural activity associated with self-referential processing of emotional stimuli was investigated using whole brain functional magnetic resonance imaging (fMRI). Fifteen healthy subjects underwent fMRI scanning while making judgments about positive and negative trait words in four conditions (self-reference, other-reference, semantic processing, and letter processing). Significant activity was observed in the right ventral anterior cingulate gyrus and the right amygdala in the ...

    Also Ranks for: Referential Processing |  negative stimuli |  cingulate gyrus |  ventral anterior |  cinguli humans
    KOL Index score: 7939

    According to sociometer theory, self-esteem serves as a barometer of the extent to which individuals are socially included or excluded by others. We hypothesized that trait self-esteem would be related to social pain responsiveness, and we used functional magnetic resonance imaging to experimentally investigate this potential relationship. Participants (n = 26) performed a cyberball task, a computerized game of catch during which the participants were excluded from the game. Participants ...

    Also Ranks for: Social Pain |  anterior cingulate |  trait esteem |  prefrontal cortex |  individuals greater degree
    KOL Index score: 7841

    AIMS: Somatoform pain disorder is associated with psychosocial dysfunction, and psychotherapies, such as cognitive behavioral therapy (CBT), are thought to provide useful interventions to address such dysfunction as well as the pain itself. However, little is known about whether CBT for somatoform pain disorder is effective, including the long-term course of the illness, in non-Western populations. We therefore tailored such a program based on an existing CBT protocol and examined its ...

    Also Ranks for: Somatoform Pain |  behavioral therapy |  japan cbt |  depressive symptoms |  disorder patients
    KOL Index score: 7285

    Pain is a multidimensional experience. Human pain perception can be modulated by subjective emotional responses. We examined this association within the context of a neuroimaging study, using functional MRI to examine neural responses to electrical pain-inducing stimuli in 15 healthy subjects (6 females; age range=20-30 years). Pain-inducing stimuli were presented during different emotional contexts, which were induced via the continuous presentation (5 s) of sad, happy, or neutral ...

    Also Ranks for: Experience Pain |  emotional context |  cinguli humans |  neural activation |  cingulate cortex
    KOL Index score: 7077

    We studied the neural activation associated with anticipations of emotional pictures using functional magnetic resonance imaging (fMRI) by directly comparing certain with uncertain anticipation conditions. While being scanned with fMRI, healthy participants (n=18) were cued to anticipate and then perceive emotional stimuli having predictable (i.e., certain) emotional valences (i.e., positive and negative), given a preceding cue, as well as cued stimuli of uncertain valence (positive or ...

    Also Ranks for: Negative Picture |  anterior cingulate |  prefrontal cortex |  insula amygdala |  image processing
    KOL Index score: 6872

    BACKGROUND: Although patients with Treatment Resistant Depression (TRD) often have impaired social functioning, few studies have investigated the effectiveness of psychosocial treatment for these patients. We examined whether adding group cognitive behavioral therapy (group-CBT) to medication would improve both the depressive symptoms and the social functioning of patient with mild TRD, and whether any improvements would be maintained over one year.

    METHODS: Forty-three patients with TRD ...

    Also Ranks for: Psychosocial Functioning |  behavioral therapy |  depressive symptoms |  resistant depression |  automatic thought
    KOL Index score: 6778

    Pain is a multidimensional phenomenon. Patients with somatoform pain disorder suffer from long-lasting pain, with the pathology being closely associated with cognitive-emotional components. Differences between these patients and controls in cerebral responses to pain stimuli have been reported. However, to our knowledge, no studies of somatoform pain disorder have evaluated altered pain-related brain activation as modulated by emotional dysregulation. We examined the distinct neural ...

    Also Ranks for: Pain Disorder |  fmri study |  patients somatoform |  neural responses |  cognitiveemotional components
    KOL Index score: 5730

    BACKGROUND: Depression is characterized by negative self-cognition. Our previous study (Yoshimura et al. 2014) revealed changes in brain activity after cognitive behavioral therapy (CBT) for depression, but changes in functional connectivity were not assessed.

    METHOD: This study included 29 depressive patients and 15 healthy control participants. Functional Magnetic Resonance Imaging was used to investigate possible CBT-related functional connectivity changes associated with negative ...

    Also Ranks for: Functional Connectivity |  cognitive behavioral therapy |  cbt depression |  magnetic resonance |  depressive symptoms
    KOL Index score: 5399

    BACKGROUND AND OBJECTIVES: Depression is characterized by low reward sensitivity in behavioral studies applying signal detection theory. We examined deficits in reward-based decision making in depressed participants during a probabilistic learning task, and used a reinforcement learning model to examine learning parameters during the task.

    METHODS: Thirty-six nonclinical undergraduates completed a probabilistic selection task. Participants were divided into depressed and non-depressed ...

    Also Ranks for: Action Selection |  reinforcement learning model |  depression female humans |  probabilistic learning |  based decision
    KOL Index score: 5296

    Pain is a multidimensional phenomenon. Previous psychological studies have shown that a person's subjective pain threshold can change when certain emotions are recognized. We examined this association with magnetoencephalography. Magnetic field strength was recorded with a 306-channel neuromagnetometer while 19 healthy subjects (7 female, 12 male; age range = 20-30 years) experienced pain stimuli in different emotional contexts induced by the presentation of sad, happy, or neutral facial ...

    Also Ranks for: Pain Stimuli |  emotional context |  neural responses |  multidimensional phenomenon |  broader relationship
    KOL Index score: 5142

    Diagnosis of psychiatric disorders based on brain imaging data is highly desirable in clinical applications. However, a common problem in applying machine learning algorithms is that the number of imaging data dimensions often greatly exceeds the number of available training samples. Furthermore, interpretability of the learned classifier with respect to brain function and anatomy is an important, but non-trivial issue. We propose the use of logistic regression with a least absolute ...

    Also Ranks for: Psychiatric Disorders |  imaging data |  functional mri |  clinical applications |  brain areas
    KOL Index score: 4800

    Functional MRI (fMRI) studies have been used to investigate how the brain processes noxious stimuli in osteoarthritis (OA) and to identify the cortical location of pain perception. However, no consensus has been reached regarding brain activity associated with pain-induced conditions in OA patients. We examined cerebral responses using intra-epidermal electrical stimulation of the . knee in knee OA patients. To replicate the pain of knee OA in terms of predictability, acute pain ...

    Also Ranks for: Pain Perception |  osteoarthritis patients |  noxious stimuli |  electrical stimulation |  brain activity


    Shinpei Yoshimura: Influence Statistics

    Sample of concepts for which Shinpei Yoshimura is among the top experts in the world.
    Concept World rank
    explanation greater levels #4
    lower trait selfesteem #4
    social pain inclusion #4
    potential relationship participants #4
    esteem anterior #4
    esteem cerebellum #4
    esteem enhance #4
    prefrontal cortex explanation #4
    social pain responsiveness #4
    fear circuit activity #5
    correlational analysis reductions #5
    paininduced conditions #5
    reappraisals transient #5
    reappraisals anticipatory #5
    reappraisal neuroimaging studies #5
    neural basis reappraisal #5
    underling neural mechanisms #5
    social pain individuals #5
    activity reappraisals #5
    regions reappraisals #5
    negative emotion encoding #5
    increased activity reappraisal #5
    transient anticipatory anxiety #5
    strategy neuroimaging #5
    neural activity reappraisals #5
    predictability acute pain #5
    cortices reappraisal #5
    encoding negative word #5
    pain perception consensus #5
    dlpfc pain matrix #5
    studies neural representation #5
    neutral faces encoding #5
    subjective anxiety reappraisal #5
    subcortical regions reappraisals #5
    paininduced conditions patients #5
    transient anticipatory #5
    amygdala increased responses #5
    reappraisals anticipatory anxiety #5
    reappraisal recruits #5
    neuroimaging studies reappraisal #5
    knee pain perception #6
    distinctive spontaneous #6
    reappraisals anxiety #6
    reappraisals reappraisal #6
    pain emotional context #6
    emotionality associative #7
    effectiveness somatoform #7
    individuals trait selfesteem #7
    activation medial prefrontal #7
    thirtyfour japanese participants #7

    Key People For Pain Disorder

    Top KOLs in the world
    Dennis C Turk†
    chronic pain fibromyalgia syndrome united states
    Daniel Joseph Daniel
    chronic pain rheumatoid arthritis fibromyalgia fm
    Michael R Von Korff
    chronic pain major depression mental disorders
    Clifford J Woolf
    spinal cord dorsal horn neuropathic pain
    Troels Staehelin Staehelin‐Jensen
    neuropathic pain whiplash injury spinal cord
    Rolf‐Detlef Treede
    neuropathic pain evoked potentials quantitative sensory testing

    Shinpei Yoshimura:Expert Impact

    Concepts for whichShinpei Yoshimurahas direct influence:Pain disorder,  Emotional support,  Cognitive behavioral therapy,  Fmri study,  Social anxiety,  Referential processing,  Pain stimuli,  Selfreferential processing.

    Shinpei Yoshimura:KOL impact

    Concepts related to the work of other authors for whichfor which Shinpei Yoshimura has influence:Social exclusion,  Major depressive disorder,  Functional connectivity,  Chronic pain,  Prefrontal cortex,  Depressive symptoms,  Resonance imaging.



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    Department of Psychology, Otemon Gakuin University, 2-1-15, Nishi-ai, Osaka, Ibaraki Japan | Faculty of Psychology, Otemon Gakuin University, 2-1-15 Nishiai, 567-8502 Ibaraki, Osaka Japan | Department of Psychology, Otemon Gakuin University, 2-1-15 N