Prominent publications by Robin A ASHINOFF

KOL Index score: 13256

Increasing evidence supports the association of squamous cell carcinoma of the finger and nail bed with human papillomavirus infection. We treated 12 patients with squamous cell carcinoma of the finger and nail bed, none of whom was originally diagnosed as having a malignant lesion. Half of the patients were referred for carbon dioxide laser ablation of what was believed to be a recalcitrant verruca vulgaris. Our objective was to evaluate these lesions for the presence of human ...

Conhecido por Human Papillomavirus |  squamous cell carcinoma |  polymerase chain reaction |  nail bed |  situ hybridization

Laser Removal of Tattoos

KOL Index score: 12960

Tattoos are placed for different reasons. A technique for tattoo removal which produces selective removal of each tattoo pigment, with minimal risk of scarring, is needed. Nonspecific methods have a high incidence of scarring, textural, and pigmentary alterations compared with the use of Q-switched lasers. With new advances in Q-switched laser technology, tattoo removal can be achieved with minimal risk of scarring and permanent pigmentary alteration.There are five types of tattoos: ...

Conhecido por Laser Removal |  switched yag |  tattoo pigment |  treatment sessions |  532 nm
KOL Index score: 12584

BACKGROUND: The Q-switched ruby laser (QSRL) (694 nm) has been used successfully in the removal of tattoos and a variety of cutaneous pigmented lesions. The frequency-doubled Q-switched neodymium:yttrium-aluminum-garnet laser (QSNd:YAG) (1064 and 532 nm) has also been shown to be effective in the treatment of tattoos, however, little has been published regarding the QSNd:YAG laser in the removal of cutaneous pigmented lesions.

OBJECTIVE: The purpose of this study is to compare the ...

Conhecido por Pigmented Lesions |  treatment qsrl |  yag laser |  q‐switched neodymium |  switched ruby
KOL Index score: 10956

BACKGROUND: With the emergence of new laser and dermatologic procedures, the need for more effective topical anesthesia continues to grow. There are now several topical anesthetics that are being used prior to laser and surgical procedures.

OBJECTIVE: To compare the degree and duration of anesthesia produced by four commonly used topical anesthetics, we performed a prospective study investigating the efficacy of EMLA (eutectic mixture of local anesthetics), ELA-Max, 4% tetracaine gel, ...

Conhecido por Topical Anesthetics |  elamax emla |  lidocaine prilocaine |  30 minutes |  application time
KOL Index score: 9898

EMLA cream (Eutectic Mixture of Local Anesthetics) is a new topical anesthetic composed of 25 mg lidocaine and 25 mg prilocaine in an oil-in-water emulsion cream. It has been found to be very effective for local anesthesia prior to venepuncture, minor surgical procedures, and pulsed dye laser (PDL) therapy for port-wine stains (PWS) in children. However, since EMLA may cause vasoconstriction of cutaneous vessels, we tried to determine whether pretreatment with EMLA decreases the efficacy ...

Conhecido por Topical Anesthetic |  pdl treatment |  emla cream |  dye laser |  lidocaine prilocaine
KOL Index score: 7839

We present the case of two patients with an unusual form of discoid lupus erythematosus that was confined almost exclusively to the palms and soles. In both patients this form of discoid lupus erythematosus did not respond to conventional therapies, which included topical steroids, intralesional steroids, prednisone, quinacrine hydrochloride, hydroxychloroquine sulfate, colchicine, and dapsone. Both patients were then treated with azathioprine. One patient dramatically improved with ...

Conhecido por Lupus Erythematosus |  successful treatment |  palms soles |  patients azathioprine |  topical steroids
KOL Index score: 6972

BACKGROUND: Both dermabrasion and high-energy pulsed carbon dioxide (CO2) laser resurfacing can improve the appearance of surgical scars. Although the results of these two procedures have been compared using historical data, a prospective evaluation has never been performed in humans.

OBJECTIVE: To prospectively compare the clinical effects of dermabrasion and high-energy pulsed CO2 laser resurfacing in the revision of surgical scars.

METHODS: Facial surgical scars in four patients were ...

Conhecido por Energy Pulsed |  carbon dioxide |  laser resurfacing |  treatment modalities |  therapy male
KOL Index score: 6395

Anthralin is an effective topical treatment for active psoriasis; however, its mechanism of action is unknown. Both TGF-alpha and its receptor, the EGF receptor, are overexpressed in active psoriatic plaques and might, therefore, play a role in psoriatic epidermal hyperplasia. In order to assess whether anthralin might act via alteration of this growth factor pathway, we examined the in vitro effects of pharmacologic concentrations of anthralin on cultured normal human keratinocytes. ...

Conhecido por Keratinocytes Anthralin |  active psoriasis |  egf receptors |  keratinocyte proliferation |  cell division
KOL Index score: 6325

BACKGROUND: Basal cell carcinomas (BCC) arising on the genitalia are exceedingly rare with an unclear pathogenesis.

OBJECTIVE: To better understand risk factors, tumor characteristics, and the possible role of human papillomavirus (HPV) in the development of BCC of the genitalia.

METHODS: 1543 records of Mohs micrographic surgery performed during a 6-year period were reviewed to identify cases of BCC arising on the genitalia. Tumor tissue was analyzed for HPV DNA by in situ ...

Conhecido por Basal Cell |  mohs micrographic surgery |  situ hybridization |  neoplasms aged |  human papillomavirus
KOL Index score: 6176

BACKGROUND: There is no single optimal treatment for multiple facial actinic keratoses. The existing therapies such as topical 5-fluorouracil, chemical peels, cryotherapy, dermabrasion, and CO2 laser resurfacing can produce prolonged recovery time or are often operator dependent.

OBJECTIVE: The purpose of this study was to investigate another therapeutic modality which provides a shorter recovery time with uniform results. We performed a prospective pilot study investigating the use of ...

Conhecido por Yag Laser |  actinic keratoses |  skin resurfacing |  therapeutic modality |  topical 5
KOL Index score: 6119

Strawberry, or capillary, hemangiomas are common vascular neoplasms, with an incidence of approximately 2.6% in neonates. They usually develop in the first few weeks of life, so that between 1 month and 1 year the incidence rises to between 8.7% and 10.1%. These lesions may grow quite large in the first year of life, and they may ulcerate or obstruct a vital organ or function. The great majority will spontaneously regress after the first year of life. Parents are often alarmed at the ...

Conhecido por Capillary Hemangiomas |  pulsed dye |  laser therapy |  surgical excision |  10 children
KOL Index score: 6066

Twelve children, 6 to 30 weeks of age (average 14.9 weeks), with port-wine stains of the head and neck were treated with the flashlamp-pumped pulsed dye laser at 585 nm and 450 microsecond pulse duration. Ten of 12 patients (83%) showed more than 50% lightening of their port-wine stains after 2.9 treatment sessions (2.9 +/- 1.4 [+/- standard deviation]). Forty-five percent of the patients demonstrated 75% or more lightening of their lesions after a mean of 3.8 treatments (+/- 1.6). No ...

Conhecido por Wine Stains |  dye laser |  pumped pulsed |  585 nm |  head neck
KOL Index score: 5556

BACKGROUND: Warts are a therapeutic challenge. New studies indicate that pulsed dye laser therapy may be effective, with clearance rates of 72 to 93%.

OBJECTIVE: To determine clearance rate in pulsed dye laser treatment of warts and compare our rate to those of other published studies.

METHODS: Thirty-three patients with 96 warts received pulsed dye laser treatment for recalcitrant plantar, digital, peri- and subungual, and body warts.

RESULTS: Forty-eight percent of patients had ...

Conhecido por Laser Treatment |  pulsed dye |  recalcitrant warts |  clearance rate |  therapeutic challenge

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Robin A ASHINOFF:Impacto especializado

Conceitos para os quaisRobin A ASHINOFFtem influência direta:Squamous cell carcinoma,  Skin cancer,  Human papillomavirus,  Laser treatment,  Basal cell,  Topical anesthetics,  12 patients,  Benign pigmented lesions.

Robin A ASHINOFF:Kol Impact

Conceitos relacionados ao trabalho de outros autores para os quaisfor which Robin A ASHINOFF tem influência:Laser treatment,  Vascular malformations,  Tattoo removal,  Pulsed dye,  Port wine,  Chronic actinic dermatitis,  Striae distensae.



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Division of Dermatology, Hackensack University Medical Center, Hackensack, New Jersey | Department of Dermatologic and Mohs Surgery, Hackensack University Medical Center, 07601, Hackensack, NJ, USA | Department of Dermatologic and Mohs Surgery, Hacke