• Disease
  • Neck
  • Neck Dissection
  • Alfio Ferlito

    Prominent publications by Alfio Ferlito

    KOL Index score: 12579

    The incidence of distant metastases in head and neck squamous cell carcinoma (SCC) is relatively small in comparison to other malignancies. Distant metastases adversely impact survival and may significantly affect treatment planning. The incidence of distant metastases is influenced by location of the primary tumor, initial T and N stage of the neoplasm, and the presence or absence of regional control above the clavicle. Patients with advanced nodal disease have a high incidence of ...

    Also Ranks for: Distant Metastases |  carcinoma head |  primary tumor |  pulmonary metastasis |  liver neoplasms
    KOL Index score: 12092

    Neuroendocrine neoplasms of the larynx have been divided into those of epithelial or neural origin. The latter consist of paragangliomas while the epithelial origin group can be divided into the typical and atypical carcinoids and small cell neuroendocrine carcinomata, the latter consisting of the oat cell type, the intermediate cell type and the combined cell type. There are now over 500 cases of neuroendocrine neoplasms of the larynx in the literature. The diagnosis is primarily based ...

    Also Ranks for: Neuroendocrine Neoplasms |  atypical carcinoid |  elective neck dissection |  chemotherapy radiotherapy |  conservative surgery
    KOL Index score: 11605

    BACKGROUND: The definitive treatment for head and neck paraganglioma (PG) is surgical excision. Unfortunately, surgery, particularly of vagal paraganglioma (VPG; "glomus vagale") and foramen jugulare ("glomus jugulare") tumors, may be complicated by injuries to the lower cranial nerves, a high price to pay for treatment for a benign tumor. Alternatively these tumors may be followed without treatment, or irradiated. The purpose of this review was to compare the existing evidence ...

    Also Ranks for: Vagal Paragangliomas |  surgery patients |  systematic study |  tumor control |  vagus nerve
    KOL Index score: 11115

    How far to extend the surgical treatment of papillary thyroid carcinoma (PTC) is still an open question. A contribution may come from intra-operative lymphatic mapping because, in other malignancies, the procedure has become an important aid in defining lymph node status. To assess the feasibility of using the sentinel lymph node (SLN) technique with the intratumoral injection of Patent Blue V dye to guide nodal dissection in PTC, 29 patients with a preoperative diagnosis of PTC and no ...

    Also Ranks for: Papillary Thyroid Carcinoma |  sentinel node |  surgical treatment |  ptc sln |  thyroid gland
    KOL Index score: 10466

    BACKGROUND: Local and/or regional recurrence and metachronous primary tumor arising in a previously irradiated area are rather frequent events in patients with head and neck squamous cell carcinoma (HNSCC). Re-treatment is associated with an increased risk of serious toxicity and impaired quality of life (QOL) with an uncertain survival advantage.

    METHODS: We analyzed the literature on the efficacy and toxicity of photon/electron-based external beam reirradiation for previously ...

    Also Ranks for: Squamous Cell |  local neoplasms |  patients reirradiation |  head neck |  neoplasm recurrence
    KOL Index score: 10199

    Thyroid cancer represents a unique biological tumor where even with the high incidence of distant metastases, the overall prognosis is not as poor as many other human cancers. The overall long-term survival in patients presenting initially with distant metastasis is approximately 50%. The overall incidence of distant metastases varies between 10 and 35%, depending upon the histology. The overall incidence is directly related to various histologies - being least in papillary thyroid ...

    Also Ranks for: Distant Metastases |  thyroid cancer |  highrisk patients |  initial presentation |  neoplasms carcinoma
    KOL Index score: 10117

    INTRODUCTION: The purpose of this paper is to determine the optimal elective treatment of the neck for patients with supraglottic and glottic squamous carcinoma. During the past century, various types of necks dissection have been employed including conventional and modified radical neck dissection (MRND), selective neck dissection (SND) and various modifications of SND.

    MATERIALS AND METHODS: A number of studies were reviewed to compare the results of MRND and SND in regional recurrence ...

    Also Ranks for: Neck Dissection |  carcinoma squamous |  patients supraglottic |  lymph nodes |  elective surgical
    KOL Index score: 9782

    Neuroendocrine neoplasms of the larynx are rare but are the most common nonsquamous tumors of this organ. In the past, there has been considerable confusion about the nature and classification of these neoplasms, but the current consensus is that there are 4 different types of laryngeal neuroendocrine tumors composed of paraganglioma, typical carcinoid, atypical carcinoid tumor, and small cell neuroendocrine carcinoma. Carcinoids and small cell neuroendocrine carcinomas are epithelial ...

    Also Ranks for: Neuroendocrine Neoplasms |  prognosis larynx |  small cell |  typical carcinoid |  partial laryngectomy
    KOL Index score: 9627

    Comorbidity, the presence of additional illnesses unrelated to the tumor, has a significant impact on the prognosis of patients with head and neck cancer. In these patients, tobacco and alcohol abuse contributes greatly to comorbidity. Several instruments have been used to quantify comorbidity including Adult Comorbidity Evaluation 27 (ACE 27), Charlson Index (CI) and Cumulative Illness Rating Scale. The ACE 27 and CI are the most frequently used indices. Information on comorbidity at ...

    Also Ranks for: Neck Cancer |  patients comorbidity |  quality life |  female head |  specific survival
    KOL Index score: 9626

    Merkel cell carcinoma (MCC) is a rare neuroendocrine neoplasm of the skin. The tumor most frequently affects elderly patients, with a preference for the head and neck. Incidence rates increase with sun exposure and after immunosuppression and organ transplantation. A significant proportion of MCC have been reported to occur in intimate association with malignant epithelial neoplasms. The genetic mechanisms underlying the development and tumor progression of MCC are poorly understood, ...

    Also Ranks for: Head Neck |  merkel cell |  patients mcc |  organ transplantation |  sun exposure
    KOL Index score: 9615

    Concurrent chemotherapy and radiotherapy (CRT) has become standard treatment for many patients with advanced head and neck squamous cell carcinoma (HNSCC). This has led to controversy concerning the role of neck dissection (ND) in this setting. The current debate is focused on N2-N3 disease and the ability of a clinical complete response to predict the absence of viable cells in the ND specimen. Proponents of a systematic planned ND argue that it improves regional control and possibly ...

    Also Ranks for: Neck Dissection |  squamous cell |  complete response |  crt hnscc |  patients residual disease
    KOL Index score: 9546

    Lymphoid proliferations of the salivary glands can be either reactive or neoplastic. Reactive lesions include the lymphoepithelial sialadenitis (LESA; also known as myoepithelial sialadenitis [MESA]) of Sjogren's syndrome. Lymphomas of the salivary glands are predominantly B-cell type and include extranodal marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT) type. The spectrum of histopathologic features of LESA/MESA includes 1) "fully benign lymphoid ...

    Also Ranks for: Salivary Glands |  lymphoepithelial sialadenitis |  cell lymphoma |  lymphoid proliferations |  malt type
    KOL Index score: 9366

    Salivary gland neoplasms are a morphologically heterogenous group of lesions that are often diagnostically challenging. In recent years, considerable progress in salivary gland taxonomy has been reached by the discovery of tumor type-specific fusion oncogenes generated by chromosome translocations. This review describes the clinicopathologic features of a selected group of salivary gland carcinomas with a focus on their distinctive genomic characteristics. Mammary analog secretory ...

    Also Ranks for: Salivary Gland |  differential diagnosis |  fusion gene |  cribriform adenocarcinoma |  clinicopathologic features
    KOL Index score: 9313

    PurposeManagement of the facial nerve is instrumental in the surgical treatment of parotid cancer.MethodsA literature search was conducted using PubMed and ScienceDirect database. A total of 195 articles were finally included into the analysis, based on relevance, scientific evidence and actuality.ResultsIn the majority of cases the facial nerve is not involved by tumor. In these cases, identification and preservation of the nerve, in addition to complete tumor removal, are essential for ...

    Also Ranks for: Facial Nerve |  parotid cancer |  tumor cases |  surgical treatment |  paralysis humans
    KOL Index score: 9125

    The significance of metastatic disease in the lymph nodes of the neck as a critical independent prognostic factor in head and neck cancer has long been appreciated. Although 19th century surgeons attempted to remove involved cervical lymph nodes at the time of resection of the primary cancer, a systematic approach to en bloc removal of cervical lymph node disease, described in detail by Jawdyński in 1888 and popularized and illustrated by Crile in the early 20th century, provided ...

    Also Ranks for: Neck Dissection |  lymph nodes |  20th century |  internal jugular vein |  accessory nerve


    Alfio Ferlito: Influence Statistics

    Sample of concepts for which Alfio Ferlito is among the top experts in the world.
    Concept World rank
    larynx confusion #1
    multiple primary larynx #1
    laryngeal cancer satisfactory #1
    neck primary tumors #1
    snuc subject #1
    insm1 marker #1
    keratosis papillary diagnosis #1
    larynx topic #1
    correct diagnosis paramount #1
    laryngeal cancer morbidity #1
    tracheax #1
    primary parapharyngeal #1
    19th century verrucous #1
    ssnd indications #1
    aggressive attempts tumors #1
    therapeutic challenge #1
    case pleomorphic rhabdomyosarcoma #1
    laryngeal neoplasms male #1
    adjuvant chemotherapy irradiation #1
    neopharyngoplasty #1
    neck neck scientific #1
    cell glottis #1
    rational replacement #1
    larynx health organization #1
    larynx nerve tissue #1
    occult disease neck #1
    laryngectomy methods #1
    life radiotherapy range #1
    dermatologic pns diagnosis #1
    hnpgs patients #1
    middle ear adenomas #1
    medieval humans terminology #1
    unconventional squamous #1
    hypopharynx multiple primary #1
    oesophagus province #1
    literature review tlm #1
    atypical carcinoid tumor #1
    laryngeal neuroendocrine tumors #1
    subglottic tumors #1
    subglottic cancer #1
    collision tumors larynx #1
    fistula head radiotherapy #1
    cases laryngeal #1
    evidence ssnd #1
    treatment general acceptance #1
    hypopharynx publication carcinoma #1
    literature hamartoma #1
    level metastases #1
    verrucous #1
    squamous cell diagnosis #1

    Key People For Neck Dissection

    Top KOLs in the world
    Jatin P Shah
    neck dissection squamous cell thyroid cancer
    Ashok R Shaha
    thyroid cancer distant metastases neck dissection
    Kevin Thomas Robbins
    neck dissection advanced head squamous cell
    Randal Scott Weber
    head neck salivary gland squamous cell
    Alfio Ferlito
    neck dissection squamous cell distant metastases
    Robert M Byers
    squamous carcinoma oral tongue neck dissection

    Alfio Ferlito:Expert Impact

    Concepts for whichAlfio Ferlitohas direct influence:Neck dissection,  Head neck,  Squamous cell,  Cell carcinoma,  Neck neoplasms humans,  Squamous cell carcinoma,  Laryngeal cancer,  Distant metastases.

    Alfio Ferlito:KOL impact

    Concepts related to the work of other authors for whichfor which Alfio Ferlito has influence:Squamous cell,  Neck dissection,  Oral cavity,  Lymph node,  Laryngeal cancer,  Nasopharyngeal carcinoma,  Salivary gland.



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    International Head and Neck Scientific Group, 35100 Padua, Italy;, a.ferlito@uniud.it | Coordinator of the International Head and Neck Scientific Group, 35125 Padua, Italy;, profalfioferlito@gmail.com | Coordinator of the International Head and Neck