An E Vanhaesebrouck: Influence Statistics

An E Vanhaesebrouck

An E Vanhaesebrouck

The Department of Veterinary Medicine, University of Cambridge, Cambridge, UK | Neurosciences Group, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, ...

An E Vanhaesebrouck: Expert Impact

Concepts for which An E Vanhaesebrouck has direct influence: Jack russell terriers , Clinical signs , Jack russell , Status epilepticus , Labrador retrievers , Veterinary medicine , Spinal epidural empyema .

An E Vanhaesebrouck: KOL impact

Concepts related to the work of other authors for which for which An E Vanhaesebrouck has influence: Clinical signs , Myasthenia gravis , Neuromuscular junction , Feline infectious peritonitis , Spinocerebellar ataxia , Neuropathic pain , Congenital myasthenic syndrome .

KOL Resume for An E Vanhaesebrouck

Year
2020

The Department of Veterinary Medicine, University of Cambridge, Cambridge, UK

2019

Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

2017

Department of Veterinary Medicine University of Cambridge Cambridge UK

2016

Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK

2015

Department of Veterinary Medicine, Veterinary Medicine School, University of Cambridge, Madingley Road, Cambridge CB3 0ES, UK.

2014

The Queen's Veterinary School Hospital, Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES, UK

2013

Department of Veterinary Medicine, Queen's Veterinary School Hospital, Cambridge University, Madingley Road, Cambridge CB3 0ES, UK

2012

Department of Medicine and Clinical Biology of Small Animals, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium

Ioannis N Plessas is now at the Royal Veterinary College, University of London, UK

Anthony C Palmer and Fernando Constantino-Casas contributed equally to this work

2011

Queen’s Veterinary School Hospital, Department of Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES

Department of Small Animal Medicine and Clinical Biology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium

2010

Department of Small Animal Medicine and Clinical Biology

2008

Department of Small Animal Medicine and Clinical Biology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium

National Veterinary School of Alfort, Maisons-Alfort, France

Prominent publications by An E Vanhaesebrouck

KOL-Index: 7769 . To date there is no evidence-based data for efficacious treatment of neuropathic pain in dogs with Chiari-like malformation (CM) and syringomyelia (SM). The objective of this prospective cross-over study was to compare the effect of gabapentin versus topiramate, as an add-on treatment to carprofen, on quality of life (QoL) of dogs experiencing signs of neuropathic pain due to CM/SM. A ...
Known for Neuropathic Pain | Quality Life | Malformation Syringomyelia | Dogs Chiari
KOL-Index: 7486 . The clinical and clinicopathological characteristics, treatment and outcome of vermicular muscle contractions (myokymia) and generalized muscle stiffness (neuromyotonia) in 37 Jack Russell terriers were evaluated retrospectively. Thirty dogs were affected by both disorders, whereas seven were presented with myokymia and never developed neuromyotonia. Clinical signs started at the mean age ...
Known for Jack Russell | Myokymia Neuromyotonia | Clinical Signs | Hereditary Ataxia
KOL-Index: 6999 . BACKGROUND: Intranasal administration of benzodiazepines has shown superiority over rectal administration for terminating emergency epileptic seizures in human trials. No such clinical trials have been performed in dogs. OBJECTIVE: To evaluate the clinical efficacy of intranasal midazolam (IN-MDZ), via a mucosal atomization device, as a first-line management option for canine status ...
Known for Status Epilepticus | Intranasal Administration | Cessation Time | Randomized Parallel
KOL-Index: 5905 . Brachial plexus trauma is a common clinical entity in small animal practice and prognostic indicators are essential early in the course of the disease. Magnetic stimulation of the radial nerve and consequent recording of the magnetic motor evoked potential (MMEP) was examined in 36 dogs and 17 cats with unilateral brachial plexus trauma. Absence of deep pain perception (DPP), ipsilateral ...
Known for Magnetic Stimulation | Brachial Plexus | Radial Nerve | Dogs Cats
KOL-Index: 5679 . BACKGROUND: Seizures are a common presenting sign in dogs with brain tumors. HYPOTHESIS/OBJECTIVES: To investigate the effect of radiotherapy on freedom from brain tumor-associated seizures and survival time in dogs. ANIMALS: Thirty-two client-owned dogs with brain tumor-associated seizures; 18 received medical treatment and radiotherapy, 14 received medical treatment alone. METHODS: ...
Known for Brain Tumors | Seizures Dogs | Retrospective Studies | Glioma Humans
KOL-Index: 5461 . A 14-year-old male domestic shorthair cat presented with an acute onset of aggressive behaviour, fear and hypersalivation. Neurological examination revealed bilateral mydriasis and left-sided facial twitching and hemiparesis. Magnetic resonance imaging (MRI) showed moderate bilateral symmetrical T2-hyperintensity along the entire hippocampus and bilateral asymmetric T2-hyperintensity in ...
Known for Temporal Lobe | Hippocampal Necrosis | Acute Onset | Medical Treatment
KOL-Index: 5197 . PURPOSE OF REVIEW: Congenital myasthenic syndromes (CMS) are a group of heterogeneous inherited disorders caused by mutations in genes encoding proteins whose function is essential for the integrity of neuromuscular transmission. This review updates the reader on the expanding phenotypic spectrum and suggested improved treatment strategies. RECENT FINDINGS: As next-generation sequencing is ...
Known for Congenital Myasthenic | Genes Mutations | Neuromuscular Transmission | Central Nervous
KOL-Index: 5158 . KEY POINTS: The physiological significance of the developmental switch from fetal to adult acetylcholine receptors in muscle (AChRs) and the functional impact of AChR clustering by rapsyn are not well studied. Using patch clamp experiments, we show that recovery from desensitization is faster in the adult AChR isoform. Recovery from desensitization is determined by the AChR ...
Known for Adult Achrs | Acetylcholine Receptors | Neuromuscular Junction | Hek293 Cells
KOL-Index: 5123 . BACKGROUND: Generalized myokymia and neuromyotonia (M/NM) in Jack Russell Terriers (JRTs) is related to peripheral nerve hyperexcitability syndrome in humans, a symptom complex resulting from diverse etiologies. OBJECTIVE: Clinical and electrodiagnostic evaluation is used to narrow the list of possible etiological diagnoses in JRTs with M/NM. ANIMALS: Nine healthy JRTs and 8 affected ...
Known for Jack Russell Terriers | Hereditary Ataxia | Clinical Signs | Generalized Myokymia
KOL-Index: 5049 . A questionnaire-based study was used to investigate the association between the findings on magnetic resonance imaging (MRI) screening for syringomyelia (SM) in 79 asymptomatic Cavalier King Charles spaniels (CKCS) and the subsequent development of clinical signs consistent with SM in later life. Owners reported clinical signs consistent with SM in 13/79 (16%) dogs at the time of the ...
Known for Clinical Signs | Magnetic Resonance | King Charles | Questionnaires Syringomyelia
KOL-Index: 4873 . SeSAME/EAST syndrome is a multisystemic disorder in humans, characterised by seizures, sensorineural deafness, ataxia, developmental delay and electrolyte imbalance. It is exclusively caused by homozygous or compound heterozygous variations in the KCNJ10 gene. Here we describe a similar syndrome in two families belonging to the Malinois dog breed, based on clinical, neurological, ...
Known for Malinois Dogs | Hearing Loss | Kcnj10 Gene | Electrolyte Imbalance
KOL-Index: 4830 . Acetylcholine receptor deficiency is the most common form of the congenital myasthenic syndromes, a heterogeneous collection of genetic disorders of neuromuscular transmission characterized by fatiguable muscle weakness. Most patients with acetylcholine receptor deficiency respond well to acetylcholinesterase inhibitors; however, in some cases the efficacy of acetylcholinesterase ...
Known for Neuromuscular Junction | Myasthenic Syndromes | Β2adrenergic Agonists | Acetylcholine Receptor
KOL-Index: 4775 . KCNA1, KCNA2, KCNA6 and KCNQ2 are associated with peripheral nerve hyperexcitability in humans. In order to determine if these genes are also involved in Jack Russell Terriers with a similar syndrome characterized by myokymia and neuromyotonia, their predicted canine orthologs were first validated experimentally. They were found either incompletely or even incorrectly annotated, mainly due ...
Known for Jack Russell Terriers | Peripheral Nerve | Hyperexcitability Syndrome | Potassium Channel
KOL-Index: 4731 . A 4-month-old female entire domestic shorthair cat presented with an acute onset of blindness, tetraparesis and subsequent generalised seizure activity. Haematology and serum biochemistry demonstrated a moderate, poorly regenerative anaemia, hypoalbuminaemia and hyperglobulinaemia with a low albumin:globulin ratio. Serology for feline coronavirus antibody was positive with an elevated ...
Known for Feline Infectious Peritonitis | Cerebrospinal Fluid | Csf Macrophages | Cats Coronavirus
KOL-Index: 4670 . Involuntary muscle hyperactivity can result from muscle or peripheral nerve hyperexcitability or central nervous system dysfunction. In humans, diseases causing hyperexcitability of peripheral nerves are grouped together under the term 'peripheral nerve hyperexcitability' (PNH). Hyperexcitability of the peripheral motor nerve can result into five different phenotypic main variants, i.e. ...
Known for Myokymia Neuromyotonia | Jack Russell | Peripheral Nerve | Potassium Channel

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The Department of Veterinary Medicine, University of Cambridge, Cambridge, UK | Neurosciences Group, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, OX3 9DS, UK | Department of Veterinary Medicine, U