 | Maria Partisani |
Prominent publications by Maria Partisani
A syndrome of peripheral fat wasting (lipodystrophy) in patients receiving long-term nucleoside analogue therapy
[ PUBLICATION ]
OBJECTIVE: To compare body composition, body fat distribution and insulin secretion in patients taking nucleoside reverse transcriptase inhibitor (NRTI) therapy.
DESIGN AND SETTING: Cross-sectional study in three French AIDS clinical centres.
PATIENTS: Forty-three HIV-infected patients on long-term NRTI therapy including stavudine (n = 27) or zidovudine (n = 16) and 15 therapy-naive HIV-infected patients (control group).
MAIN OUTCOME MEASURES: Fat wasting was assessed by physical ...
| Also Ranks for: Fat Wasting | stavudine zidovudine | lipodystrophy patients | body composition | tissue adult |
BACKGROUND: Fat distribution abnormalities have been reported in patients treated with various antiretroviral drug regimens. The LIPOCO study is an ongoing observational study of unselected HIV-infected patients which aims to better characterize such disorders and their metabolic correlations.
METHODS: Cross-sectional analysis of data collected at baseline in the first 154 male patients included. Investigators divided patients into four predetermined clinical categories of fat ...
| Also Ranks for: Fat Distribution | computed tomography | antiretroviral therapy | insulin levels | patients lipoatrophy |
HIV-associated Hodgkin lymphoma during the first months on combination antiretroviral therapy
[ PUBLICATION ]
Hodgkin lymphoma (HL) incidence with HIV infection may have increased with the introduction of combination antiretroviral therapy (cART), suggesting that immune reconstitution may contribute to some cases. We evaluated HL risk with cART during the first months of treatment. With 187 HL cases among 64 368 HIV patients in France, relative rates (RRs) and 95% confidence intervals (CIs) of HL were estimated using Poisson models for duration of cART, CD4 count, and HIV load, with and without ...
| Also Ranks for: Hl Risk | cd4 count | hodgkin lymphoma | antiretroviral therapy | cart initiation |
Increased risk of myocardial infarction with duration of protease inhibitor therapy in HIV-infected men
[ PUBLICATION ]
BACKGROUND: In the current context of dyslipidaema, hyperglycaema and lipodystrophia observed among HIV-seropositive subjects, it is important to study the risk of myocardial infarction (MI) in this population. The French Hospital Database on HIV, which includes a large number of seropositive subjects followed for substantial periods, offers the opportunity to analyse the impact of protease inhibitors (PI) on the risk of MI among men.
METHODS: Cox model was used to study the risk factors ...
| Also Ranks for: Myocardial Infarction | cox model | inhibitors risk | protease inhibitor | seropositive subjects |
Key People For Fat Wasting
Maria Partisani:Expert Impact
Concepts for whichMaria Partisanihas direct influence:Fat wasting, Fat distribution, Stavudine zidovudine, Myocardial infarction, Hl risk, Lipodystrophy patients, Cd4 count, Antiretroviral therapy.
Maria Partisani:KOL impact
Concepts related to the work of other authors for whichfor which Maria Partisani has influence:Antiretroviral therapy, Hiv infection, Protease inhibitors, Cardiovascular disease, Insulin resistance, Metabolic syndrome, Human immunodeficiency virus.
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