• Disease
  • Emergency
  • Emergency Department
  • Anna Holdgate

    Prominent publications by Anna Holdgate

    KOL Index score: 22173

    BACKGROUND: Renal colic is a common cause of acute severe pain. Both opioids and nonsteroidal anti-inflammatory drugs (NSAIDs) are recommended for treatment, but the relative efficacy of these drugs is uncertain.

    OBJECTIVES: To examine the benefits and disadvantages of NSAIDs and opioids for the management of pain in acute renal colic.

    SEARCH STRATEGY: We searched the Cochrane Renal Group's specialised register (May 2003), the Cochrane Central Register of Randomised Controlled Trials ...

    Also Ranks for: Nsaids Opioids |  acute renal |  trials pethidine |  vomiting patients |  higher incidence
    KOL Index score: 13085

    OBJECTIVE: To examine the relative benefits and disadvantages of non-steroidal anti-inflammatory drugs (NSAIDs) and opioids for the management of acute renal colic.

    DATA SOURCES: Cochrane Renal Group's specialised register, Cochrane central register of controlled trials, Medline, Embase, and reference lists of retrieved articles.

    REVIEW METHODS: Randomised controlled trials comparing any opioid with any NSAID in acute renal colic if they reported any of the following outcomes: patient ...

    Also Ranks for: Acute Renal Colic |  nsaids opioids |  steroidal anti |  pain scores |  relative efficacy
    KOL Index score: 12741

    OBJECTIVES: The objective was to describe the epidemiology of dyspnea presenting to emergency departments (EDs) in the Asia-Pacific region, to understand how it is investigated and treated and its outcome.

    METHODS: Prospective interrupted time series cohort study conducted at three time points in EDs in Australia, New Zealand, Singapore, Hong Kong, and Malaysia of adult patients presenting to the ED with dyspnea as a main symptom. Data were collected over three 72-hour periods and ...

    Also Ranks for: Emergency Departments |  new zealand |  patients dyspnea |  hong kong |  hospital mortality
    KOL Index score: 12262

    BACKGROUND: Renal colic is a common cause of acute severe pain. Both opioids and nonsteroidal anti-inflammatory drugs (NSAIDs) are recommended for treatment, but the relative efficacy of these drugs is uncertain.

    OBJECTIVES: To examine the benefits and disadvantages of NSAIDs and opioids for the management of pain in acute renal colic.

    SEARCH STRATEGY: We searched the Cochrane Renal Group's specialised register (May 2003), the Cochrane Central Register of Randomised Controlled Trials ...

    Also Ranks for: Nsaids Opioids |  acute renal |  nonsteroidal anti |  higher incidence |  randomized controlled
    KOL Index score: 12099

    OBJECTIVE: To describe the clinical features and laboratory findings in patients with definite red-bellied black snake (RBBS; Pseudechis porphyriacus) bites, including correlation with results of venom assays.

    DESIGN, PATIENTS AND SETTING: Prospective cohort study of patients with definite RBBS bites, recruited to the Australian Snakebite Project from January 2002 to June 2010.

    MAIN OUTCOME MEASURES: Clinical and laboratory features of envenoming; peak venom concentrations and antivenom ...

    Also Ranks for: Clinical Effects |  pseudechis porphyriacus |  venom concentrations |  black snake |  systemic symptoms
    KOL Index score: 11853

    OBJECTIVES: The objective was to determine whether the introduction of intranasal (IN) fentanyl for children with acute pain would reduce the time to analgesic administration in a mixed adult and pediatric emergency department (ED).

    METHODS: A protocol for IN fentanyl (1.5 microg/ kg) for children age 1-15 years presenting with acute pain was introduced to the department. All children who received intravenous (IV) morphine in the 7 months prior to the introduction of the protocol and ...

    Also Ranks for: Morphine Fentanyl |  analgesic administration |  emergency department |  acute pain |  opioid child child
    KOL Index score: 11400

    BACKGROUND: Early goal-directed therapy (EGDT) has been endorsed in the guidelines of the Surviving Sepsis Campaign as a key strategy to decrease mortality among patients presenting to the emergency department with septic shock. However, its effectiveness is uncertain.

    METHODS: In this trial conducted at 51 centers (mostly in Australia or New Zealand), we randomly assigned patients presenting to the emergency department with early septic shock to receive either EGDT or usual care. The ...

    Also Ranks for: Early Septic Shock |  patients egdt |  length hospital stay |  emergency department |  intravenous fluids
    KOL Index score: 9882

    BACKGROUND: Patients with paroxysmal supraventricular tachycardia frequently present to the Emergency Department. Where vagal manoeuvres fail, the two most commonly used drugs are adenosine and calcium channel antagonists. Both are known to be effective but both have a significant side-effect profile.

    OBJECTIVES: To examine the relative effects of adenosine and calcium channel antagonists and, if possible, to determine which is most appropriate for the management of supraventricular ...

    Also Ranks for: Supraventricular Tachycardia |  calcium channel |  verapamil adenosine |  emergency department |  vagal manoeuvres
    KOL Index score: 9774

    OBJECTIVE: To review the relative efficacy and safety of enteral vs intravenous (IV) rehydration therapy in treating childhood gastroenteritis.

    DATA SOURCES: MEDLINE, EMBASE, and the Cochrane Controlled Trials Register databases were searched. Known investigators and expert bodies were contacted to locate unpublished and ongoing studies.

    STUDY SELECTION: Studies were selected based on the following criteria: randomized or quasi-randomized trials; children younger than 15 years with a ...

    Also Ranks for: Rehydration Therapy |  randomized controlled |  children gastroenteritis |  weight gain |  length hospital stay
    KOL Index score: 9456

    OBJECTIVES: To test the agreement between the visual analogue scale (VAS) and a verbal numeric rating scale (VNRS) in measuring acute pain, and measure the minimum clinically significant change in VNRS.

    METHODS: Patients scored their pain by the VAS and the VNRS, then re-scored their pain every 30 min for up to 2 h. Patients also recorded whether their pain had improved or worsened. Agreement between scores was evaluated, and where patients scored their pain as 'a bit worse' or 'a bit ...

    Also Ranks for: Visual Analogue Scale |  acute pain |  vnrs patients |  numeric rating |  95 differences
    KOL Index score: 9249

    STUDY OBJECTIVE: We determine whether emergency physician-provided deep sedation with 1:1 ketofol versus propofol results in fewer adverse respiratory events requiring physician intervention when used for procedural sedation and analgesia.

    METHODS: Consenting patients requiring deep sedation were randomized to receive either ketofol or propofol in a double-blind fashion according to a weight-based dosing schedule. The primary outcome was the occurrence of a respiratory adverse event ...

    Also Ranks for: Procedural Sedation |  propofol ketofol |  3 95 |  respiratory adverse |  humans hypnotics
    KOL Index score: 8940

    OBJECTIVE: Increasing demand to reduce patient waiting times and improve patient flow has led to the introduction of a number of strategies such as fast track and patient streaming. The triage nurse is primarily responsible for identifying suitable patients, based on prediction of likely admission or discharge. The aim of the present study was to explore the accuracy with which triage nurses predict patient disposition.

    METHODS: Over two separate 1-week periods, triage nurses at two ...

    Also Ranks for: Triage Nurses |  discharge patients |  patient disposition |  increasing demand |  service hospital
    KOL Index score: 8764

    BACKGROUND: Anaphylaxis is generally unanticipated and requires emergency management. Therefore, the biological mediators in human beings have been difficult to define.

    OBJECTIVE: Our aim was to identify cytokines and chemokines whose concentrations increase during anaphylaxis in human beings and to determine how each correlates with severity.

    METHODS: We measured the concentrations of potential mediators, including cytokines, chemokines, mast cell tryptase (MCT), and histamine, over 3 ...

    Also Ranks for: Human Anaphylaxis |  acute allergic reactions |  mct histamine |  reaction severity |  elevated serum
    KOL Index score: 8600

    BACKGROUND: Emergency departments (EDs) are pressured environment where patients with supportive and palliative care needs may not be identified. We aimed to test the predictive ability of the CriSTAL (Criteria for Screening and Triaging to Appropriate aLternative care) checklist to flag patients at risk of death within 3 months who may benefit from timely end-of-life discussions.

    METHODS: Prospective cohorts of >65-year-old patients admitted for at least one night via EDs in five ...

    Also Ranks for: Prospective Validation |  risk death |  australia ireland |  emergency department |  3 months
    KOL Index score: 8453

    STUDY OBJECTIVE: We determine whether single-dose activated charcoal (SDAC) administration after citalopram overdose reduces the proportion of patients developing abnormal QT prolongation.

    METHODS: Data were collected retrospectively for citalopram overdose patients presenting to 8 emergency departments. Demographics, dose, coingested drugs, SDAC administration, and serial ECGs were extracted from medical records. The primary outcome was the proportion of patients who had an observed ...

    Also Ranks for: Qt Prolongation |  activated charcoal |  torsade pointes |  overdose patients |  coingested drugs


    Anna Holdgate: Influence Statistics

    Sample of concepts for which Anna Holdgate is among the top experts in the world.
    Concept World rank
    patient satisfaction analgesia #1
    ketofol versus #1
    hydronephrosis focused training #1
    hydronephrosis perinephric stranding #1
    hydronephrosis ureteric #1
    age groups procedures #1
    opioids heterogeneity #1
    titrated intravenous morphine #1
    trials pethidine #1
    bvm preoxygenation #1
    1025 391 cases #1
    intervention sedating physician #1
    fracture dislocated shoulders #1
    accuracy epu #1
    radiologists kappa #1
    epu detection #1
    formal radiological imaging #1
    —the poker study #1
    register 2003 #1
    accuracy nonrenal #1
    nsaids vomiting #1
    included sedative #1
    ecg electrode placement #1
    versus opioids #1
    analgesia objectives #1
    nonrenal abnormality #1
    pethidine higher #1
    pethidine higher rate #1
    communication stress levels #1
    vnrs pain #1
    opioids higher incidence #1
    competence colic #1
    nsaids opioids #1
    interpreting noncontrast #1
    opioid pethidine #1
    cohorts demographics #1
    patient rated pain #1
    pooled vomiting #1
    clinicians emergency clinicians #1
    nsaids greater reductions #1
    buscopan median #1

    Key People For Emergency Department

    Top KOLs in the world
    Carlos Arturo Camargo,
    emergency department acute asthma united states
    Jesse M Pines
    emergency department united states chest pain
    Judd Eric Hollander
    emergency department chest pain myocardial infarction
    Michael John Schull
    emergency department united states heart failure
    Ian Gilmour Stiell
    emergency department cardiac arrest pulmonary embolism
    Brian Hunter Rowe
    acute asthma emergency department air pollution

    Anna Holdgate:Expert Impact

    Concepts for whichAnna Holdgatehas direct influence:Emergency department,  Emergency departments,  Supraventricular tachycardia,  Femoral vein,  Nsaids opioids,  New zealand,  Triage nurses,  Patient flow.

    Anna Holdgate:KOL impact

    Concepts related to the work of other authors for whichfor which Anna Holdgate has influence:Septic shock,  Emergency department,  Severe sepsis,  Renal colic,  Fluid resuscitation,  Acute pain,  Hospital mortality.



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    Department of Emergency MedicineLiverpool Hospital Sydney New South Wales Australia | Department of Emergency Medicine, Liverpool Hospital, Sydney, Australia and University of New South Wales (Southwest Clinical School), Sydney, Australia. | Southwes