• KOLs
  • Beclin 1
  • Jian-Qiang Ni
JIAN-QIANG NI

JIAN-QIANG NI

Department Of Neurology, The First Affiliated Hospital Of Soochow University, Suzhou, Jiangsu, China. Electronic Address: Njq@suda.edu.cn.

Direct Impact

Concepts for which JIAN-QIANG NI has direct influence:

beclin 1
diabetic stroke
chronic migraine
hepatocellular carcinoma
botulinum toxin
protective role
nutritional intervention

External impact

Concepts related to the work of other authors for which JIAN-QIANG NI has influence:

ischemic stroke
sodium butyrate
neuropathic pain
hydrogen sulfide
spinal cord injury
muscle mass
cardiac cells

Prominent publications by JIAN-QIANG NI

KOL-Index: 65 Hydrogen sulfide (H2S) is recognized to be a novel mediator after carbon monoxide and nitric oxide in the organism. It can be produced in various mammalian tissues and exert many physiological effects in many systems including the cardiovascular system. A great amount of recent studies have demonstrated that endogenous H2S and exogenous H2S-releasing compounds (such as NaHS, Na2S, and ...
Known for
Exogenous Endogenous | Cardiovascular Ischemia | Role Hydrogen | Sulfide Myocardial
KOL-Index: 30 Central post-stroke pain (CPSP) is a disabling condition in stroke patients. It is a type of neuropathic pain for which the mechanism and relevant drug pathways remain unknown. Inflammatory response and central disinhibition have been suggested recently. Our previous research has shown targeting P2X4 receptors (P2X4R) may be effective in the treatment of CPSP, but the downstream pathway of ...
Known for
Tumor Necrosis Factor Alpha | Disinhibition Tnf | Surface Gabaar | Mechanical Pain Threshold
KOL-Index: 27 OBJECTIVE: The research aim was to investigate the effects of dl-3-n-butylphthalide (NBP) on the level of circulating endothelial progenitor cells (EPCs) and clinical outcome in patients with acute ischemic stroke (AIS). MATERIALS AND METHODS: A total of 170 patients were included and randomly assigned to NBP group and control group. All patients were administrated a basic antiplatelet and ...
Known for
Additional Nbp | Nihss Therapy | Neurological Function | Pearson
KOL-Index: 26 Background and PurposeAs a very common risk of adverse outcomes of the ischemic stroke patients, sarcopenia is associated with infectious complications and higher mortality. The goal of this retrospective study is to explore the predictive value of serum Cr/CysC ratio in acute ischemic stroke patients receiving nutritional intervention.MethodsWe reviewed adult patients with AIS from December ...
Known for
Creatinine Cystatin | Months Ais | Predictive Serum
KOL-Index: 24 As the main organelles for the clearance of damaged proteins and damaged organelles, the function of lysosomes is crucial for maintaining the intracellular homeostasis of long-lived neurons. A stable acidic environment is essential for lysosomes to perform their functions. TMEM175 has been identified as a new K+ channel that is responsible for regulating lysosomal membrane potential and pH ...
Known for
Neuronal Lysosomal Dysfunction | Male Sprague-Dawley Rats | Cathepsin-B | Lysosomal Membrane Potential
KOL-Index: 24 Central poststroke pain (CPSP) is a neuropathic pain syndrome that usually occurs after cerebrovascular accidents. Currently, the pathogenesis of CPSP is not fully understood. Purinergic P2X4 receptor (P2X4R) is implicated in neuropathic pain including CPSP. Herein, we demonstrated that the levels of microRNA-133b-3p (miR-133b-3p), which targets P2X4R transcripts, were significantly ...
Known for
Rats Mir-133b-3p | Gabapentin | P2x4r Vpl | Decreased Plasma
KOL-Index: 19 Although recent studies have implicated serotonin 5-HT1B/D receptors in the nociceptive sensitivity of primary afferent neurons, the underlying molecular and cellular mechanisms remain unclear. In this study, we identified a novel functional role of the 5-HT1D receptor subtype in regulating A-type potassium (K(+)) currents (IA) as well as membrane excitability in small trigeminal ganglion ...
Known for
G-Protein | Small Trigeminal Ganglion Tg | Ht1b Receptors | Sustained Delayed Rectifier K
KOL-Index: 19 Stroke is the leading cause of disability and death in the world. Central post-stroke pain (CPSP), a central neuropathic pain syndrome occurring after cerebral stroke, is a serious problem. But on account of the lack of reliable animal models, the mechanisms underlying CPSP remains poorly understood. To better understand of the pathophysiological basis of CPSP, we developed and characterized ...
Known for
Alleviation | Pain Cpsp | Post Stroke | Intra-Thalamic Autologous Blood
KOL-Index: 16 The aim of this study was to investigate the alterations in regional homogeneity assessed by fMRI in patients with migraine without aura (MWoA). Fifty-six eligible MWoA patients and 32 matched healthy volunteers were enrolled in this study. MWoA patients were divided into three groups according to the headache days per month within 3 months: infrequent episodic migraine (IEM) group, frequent ...
Known for
Adjacent Voxels | Decreased Iem | Chronic Migraine | Middle Temporal
KOL-Index: 16 Vestibular migraine (VM) is a multidisciplinary disease under exploration. Multiple temporal patterns of vertigo and migraine make it difficult to diagnose VM, and their effect on the clinical features of VM is still unclear. Here we investigated the clinical features of VM under three temporal patterns. 172 VM patients were enrolled in this study and divided into three groups: 86 patients ...
Known for
Onset Vertigo | Trigeminal Pain Pathway | Lower Frequency | Clarification

Department of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China. Electronic address: njq@suda.edu.cn.

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