Prominent publications by Yufan Yang

KOL Index score: 8402

The activation of microglia and inflammatory responses is essential for the process of intracerebral hemorrhage (ICH)-induced secondary brain injury (SBI). In this study, we investigated the effects of luteolin on ICH-induced SBI and the potential mechanisms. Autologous blood was injected to establish the ICH model in vivo, and oxyhemoglobin (OxyHb) was used to mimic the ICH model in vitro. We found that the administration of luteolin significantly improved motor and sensory impairments ...

Bekannt für Intracerebral Hemorrhage |  neuroprotective effects luteolin |  tolllike receptor |  alleviates neuroinflammation |  nf κb
KOL Index score: 8271

Upregulation of neuronal oxidative stress is involved in the progression of secondary brain injury (SBI) following intracerebral hemorrhage (ICH). In this study, we investigated the potential effects and underlying mechanisms of luteolin on ICH-induced SBI. Autologous blood and oxyhemoglobin (OxyHb) were used to establish in vivo and in vitro models of ICH, respectively. Luteolin treatment effectively alleviated brain edema and ameliorated neurobehavioral dysfunction and memory loss in ...

Bekannt für Intracerebral Hemorrhage |  nrf2 pathway |  ichinduced sbi |  underlying mechanisms |  autologous blood
KOL Index score: 7339

BACKGROUND: Inflammation plays an important role in the initiation and progression of cervicocranial arterial dissection (CCAD). New inflammatory indices derived from full cell blood count may be associated with increased risk of acute ischemic stroke (AIS) caused by CCAD. The goal of this study is to evaluate the diagnostic performances of neutrophil to lymphocyte ratio (NLR) and lymphocyte to monocyte ratio (LMR) in CCAD.

METHOD: We retrospectively analyzed 52 patients with AIS caused ...

Bekannt für Acute Ischemic Stroke |  lymphocyte ratio |  nlr lmr |  ais ccad |  cervicocranial arterial
KOL Index score: 1273

Background and PurposeAs a very common risk of adverse outcomes of the ischemic stroke patients, sarcopenia is associated with infectious complications and higher mortality. The goal of this retrospective study is to explore the predictive value of serum Cr/CysC ratio in acute ischemic stroke patients receiving nutritional intervention.MethodsWe reviewed adult patients with AIS from December 2019 to February 2020. Patients with acute kidney injury were excluded and all patients received ...

Bekannt für Serum Creatinine
KOL Index score: 854

Central poststroke pain (CPSP) is a neuropathic pain syndrome that usually occurs after cerebrovascular accidents. Currently, the pathogenesis of CPSP is not fully understood. Purinergic P2X4 receptor (P2X4R) is implicated in neuropathic pain including CPSP. Herein, we demonstrated that the levels of microRNA-133b-3p (miR-133b-3p), which targets P2X4R transcripts, were significantly downregulated in the ventral posterolateral nucleus of the thalamus (VPL), cerebrospinal fluid (CSF), and ...

Bekannt für P2x4 Receptor |  neuropathic pain
KOL Index score: 447

Background and Purpose: Neutrophil to lymphocyte ratio (NLR) is positively associated with poor prognosis in patients with cerebral infarction. The goal of this prospective study is to explore the predictive value of NLR in patients with acute ischemic stroke (AIS) caused by cervicocranial arterial dissection (CCAD). Methods: Ninety-nine patients with AIS caused by CCAD met criteria for inclusion and exclusion were selected for this study. We collected baseline data on the admission ...

Bekannt für Arterial Dissection |  3 months |  modified rankin |  scale score

Schlüsselpersonen für Intracerebral Hemorrhage

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Yufan Yang:Expertenwirkung

Konzepte für welcheYufan Yanghat direkten Einfluss:Intracerebral hemorrhage,  Nlr ais,  Patients poor outcome,  Poor outcome patients,  Ais ccad,  Nlr patients,  Patients nlr,  Ccad nlr.

Yufan Yang:KOL -Auswirkungen

Konzepte im Zusammenhang mit der Arbeit anderer Autoren, für diefor which Yufan Yang hat Einfluss:Intracerebral hemorrhage,  Dezocine tolerance,  Nrf2 activators,  Brain volume,  Nlrp3 inflammasomes,  Large artery occlusion,  Honeybush extracts.



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Departments of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China | Department of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China. | Departments of Neurology, The First Affili