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    • Temporal Lobe
    • Yukio Kimura
    • Yukio Kimura: Influence Statistics

      Yukio Kimura

      Yukio Kimura

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      From the Departments of Radiology (H.F., N.Sato, Y.K., M.K., E.C., Y.S.). | Department of Radiology, National Center Hospital, National Center of Neurology and Psychiatry, ...

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      Yukio Kimura:Expert Impact

      Concepts for whichYukio Kimurahas direct influence:Temporal lobe,Temporal lobe epilepsy,Gray matter,Lobe epilepsy,Hippocampal sclerosis,Tuberous sclerosis complex,Zebra sign,Cingulate island sign.

      Yukio Kimura:KOL impact

      Concepts related to the work of other authors for whichfor which Yukio Kimura has influence:Amyotrophic lateral sclerosis,Temporal lobe epilepsy,Lewy bodies,White matter,Brain age,Resonance imaging,Amygdala enlargement.

      KOL Resume for Yukio Kimura

      Year
      2022

      From the Departments of Radiology (H.F., N.Sato, Y.K., M.K., E.C., Y.S.).

      Department of Radiology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan

      2021

      Department of Radiology, National Center Hospital, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashi-cho, Kodaira, Tokyo, Japan

      2020

      Department of Radiology, National Center of Neurology and Psychiatry, 4-1-1 Ogawa-Higashi, Kodaira, Tokyo, 187-8551, Japan. Electronic address:

      Radiology (N.S., Y.S., Y.K.).

      2019

      From the Department of Radiology (Yukio K., Y. Shigemoto, E.M., F.S., N.S.), National Center Hospital, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan.

      Department of Radiology, National Center of Neurology and Psychiatry, 4-1-1, Ogawa-Higashi, Kodaira, 187-8551, Tokyo, Japan

      2018

      From the National Center Hospital (A. Ishiyama, Y.K., Y.S., N.S., M.S.); National Institute of Neuroscience (A. Ishiyama, I.N.); Medical Genome Center (A. Iida, I.N.), National Center of Neurology and Psychiatry, Tokyo; Kawasaki Municipal Tama Hospital (Y.M.), St. Marianna University School of Medicine, Kanagawa; and Japanese Red Cross Musashino Hospital (M.O.), Tokyo, Japan.

      2017

      Department of Radiology, National Center of Neurology and Psychiatry, 4-1-1 Ogawa-Higashi, Kodaira, 187-0031, Tokyo, Japan

      2016

      National Center Hospital of Neurology and Psychiatry Department of Radiology Tokyo Japan

      2014

      Departments of Radiology, National Center Hospital of Neurology and Psychiatry Tokyo Japan

      2013

      Department of Radiology, National Center Hospital of Neurology and Psychiatry, 4-1-1 Ogawahigashi, Kodaira, 187-8551, Tokyo, Japan

      2012

      Epilepsy Center, National Center of Neurology and Psychiatry, Tokyo

      Department of Radiology, National Center Hospital, National Center of Neurology and Psychiatry, Kodaira

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      Sample of concepts for which Yukio Kimura is among the top experts in the world.
      Concept World rank
      flair cns lesions #4
      grade dti analysis #4
      cst brainstem abnormalities #4
      tracers precise detection #4
      methodsthe clinical severity #4
      pontine fiber #4
      cst dorsal portion #4
      tubers t1wi #4
      nuclear imaging epilepsy #4
      abnormal pattern cst #4
      senda globus #4
      complex t1wi #4
      normal cst classification #4
      cortical tubers t2wi #4
      detection cortical tubers #4
      t1wi chemical #4
      childhood senda bpan #4
      nigra carrier #4
      heterotopia lis #4
      tients development #4
      basal ganglia deformity #4
      transient globus pallidus #4
      fiber abnormal #4
      cortical tubers t1wi #4
      tubers t2wi #4
      pallidus senda #4
      suggests senda #4
      selective t2wi #4
      nigra carrier proteins #4
      sbh normal #4
      purposealthough epilepsy #5
      temporofrontal lobe #5
      tlemethodswe #5
      brainstem deformities #5
      chess case reports #5
      dystrophies substantia #5
      cryptogenic late #5
      lateonset tle #5
      case reports t1wi #5
      t2wi flair images #5
      15direction dti #5
      t1wi chess #5
      tubers adjacent #5
      12 spm12 #5
      latetle #5
      sign zebra #6
      zebra sign patients #6
      patients zebra sign #6
      51 patients tle #6
      moved randomized #6
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      Prominent publications by Yukio Kimura

      KOL-Index: 10384

      PURPOSE: Psychosis is one of the most important psychiatric comorbidities in temporal lobe epilepsy (TLE), and its pathophysiology still remains unsolved. We aimed to explore the connectivity differences of structural neuroimaging between TLE with and without psychosis using a graph theoretical analysis, which is an emerging mathematical method to investigate network connections in the brain as a small-world system.

      MATERIALS AND METHODS: We recruited 11 TLE patients with unilateral ...

      Known for Graph Theoretical Analysis | Temporal Lobe | Tle Psychosis | Connectivity Differences | Unilateral Hippocampal Sclerosis
      KOL-Index: 10040

      Static encephalopathy of childhood with neurodegeneration in adulthood (SENDA) is a recently established disorder that is a subtype of neurodegeneration with brain iron accumulation (NBIA). We presented the first case report of SENDA of a 39-year-old female. She had psychomotor retardation from childhood and remained static for two decades. Then, at the age of 30, she developed severe dystonia and parkinsonism. Brain MRI revealed T2-weighted hypointensity signal in the globus pallidus ...

      Known for Static Encephalopathy | Tensor Imaging | Childhood Neurodegeneration | Adulthood Senda | Substantia Nigra
      KOL-Index: 9435

      BACKGROUND: Despite recent advances in diffusion MRI (dMRI), there is still limited information on neurite orientation dispersion and density imaging (NODDI) in temporal lobe epilepsy (TLE). This study aimed to demonstrate neurite density and dispersion in TLE with and without hippocampal sclerosis (HS) using whole-brain voxel-wise analyses.

      MATERIAL AND METHODS: We recruited 33 patients with unilateral TLE (16 left, 17 right), including 14 patients with HS (TLE-HS) and 19 MRI-negative ...

      Known for Neurite Density | Orientation Dispersion | Lobe Epilepsy | Icvf Odi | Diffusion Imaging
      KOL-Index: 9045

      PURPOSE: Cases of temporal lobe epilepsy (TLE) with ipsilateral amygdala enlargement (AE) have increasingly been reported. However, the white matter (WM) abnormalities of TLE patients with AE remain poorly investigated. Here we explored macrostructural and microstructural WM abnormalities in TLE patients with AE compared to normal controls and TLE patients with hippocampal sclerosis (HS).

      MATERIAL AND METHODS: We selected 17 patients with unilateral TLE with AE (TLE-AE) based on ...

      Known for Hippocampal Sclerosis | Temporal Lobe Epilepsy | Amygdala Enlargement | Tle Patients | White Matter
      KOL-Index: 8740

      ObjectiveDementia with Lewy bodies (DLB) is often cited as the second most common dementia after Alzheimer’s disease (AD). It is clinically important to distinguish DLB from AD because specific side effects of antipsychotic drugs are limited to DLB. The relative preservation of cingulate glucose metabolism in the posterior cingulate gyri versus that in the precuni, known as the cingulate island sign (CIS), in patients with DLB compared with AD is supposed to be highly specific for ...

      Known for Cingulate Island Sign | Lewy Bodies | Alzheimer Disease | Perfusion Spect | Sensitivity Specificity
      KOL-Index: 8330

      PURPOSE: The purpose of the present retrospective study was to evaluate the sensitivity of susceptibility-weighted imaging (SWI) compared to conventional spin-echo T2-weighted and T2*-weighted images in detecting iron deposition in the motor cortex of amyotrophic lateral sclerosis (ALS) patients in comparison with age-matched normal controls. We also investigated the etiology of the low signal referring to the pathology of one autopsy case.

      METHODS: This retrospective magnetic resonance ...

      Known for Motor Cortex | Lateral Sclerosis | Image Interpretation | Signal Intensity | Weighted Imaging
      KOL-Index: 8068

      BACKGROUND: In addition to occipital hypoperfusion, preserved metabolism of the posterior cingulate gyri (PCG) relative to the precunei is known as the cingulate island sign (CIS) in the patients with dementia with Lewy bodies (DLB). CIS has been detected using [(18)F]fluorodeoxyglucose positron emission tomography but not using brain perfusion single-photon emission computed tomography (SPECT). The purpose of this study was to optimize brain perfusion SPECT to enable differentiation of ...

      Known for Cingulate Island Sign | Lewy Bodies | Dlb Cis | Patients Dementia | Alzheimer Disease
      KOL-Index: 7709

      Epilepsy is a diverse brain disorder, and the pathophysiology of its various forms and comorbidities is largely unknown. A recent machine learning method enables us to estimate an individual’s “brain-age” from MRI; this brain-age prediction is expected as a novel individual biomarker of neuropsychiatric disorders. The aims of this study were to estimate the brain-age for various categories of epilepsy and to evaluate clinical discrimination by brain-age for (1) the effect of psychosis on ...

      Known for Age Prediction | Tle Psychosis | Based Brain | Lobe Epilepsy | Neuropsychiatric Disorders
      KOL-Index: 6700

      Transmantle dysplasia is a rare type of focal cortical dysplasia (FCD) characterized by expansion of the cortex from the deep white matter to the surface and in which there is a FCD IIA or IIB pathologic pattern. To characterize possible mechanisms underlying this regional disorder of radial migrating cells, we studied the expression patterns of neocortical layer-specific markers using immunohistochemistry in surgical specimens from 5 FCD IIA and 4 FCD IIB cases in children. All neuronal ...

      Known for Focal Cortical Dysplasia | Transmantle Sign | Specific Marker | White Matter | Iia Iib
      KOL-Index: 6308

      Graph theory is an emerging method to investigate brain networks. Altered cerebral blood flow (CBF) has frequently been reported in temporal lobe epilepsy (TLE), but graph theoretical findings of CBF are poorly understood. Here, we explored graph theoretical networks of CBF in TLE using arterial spin labeling imaging. We recruited patients with TLE and unilateral hippocampal sclerosis (HS) (19 patients with left TLE, and 21 with right TLE) and 20 gender- and age-matched healthy control ...

      Known for Temporal Lobe Epilepsy | Hippocampal Sclerosis | Graph Theoretical | Patients Tle | Cerebral Blood
      KOL-Index: 6112

      We used quantitative susceptibility mapping (QSM) to assess the brain iron deposition in 28 patients with the cerebellar subtype of multiple system atrophy (MSA-C), nine patients with spinocerebellar ataxia type 6 (SCA6), and 23 healthy controls. Two reviewers independently measured the mean QSM values in brain structures including the putamen, globus pallidus, caudate nucleus, red nucleus, substantia nigra, and cerebellar dentate nucleus. A receiver operating characteristics (ROC) ...

      Known for Spinocerebellar Ataxia Type | Iron Deposition | Multiple Atrophy | Quantitative Susceptibility | Dentate Nucleus
      KOL-Index: 5979

      BACKGROUND AND PURPOSE: Automated subfield volumetry of hippocampus is desirable for use in temporal lobe epilepsy (TLE), but its utility has not been established. Automatic segmentation of hippocampal subfields (ASHS) and the new version of FreeSurfer software (ver.6.0) using high-resolution T2-weighted MR imaging are candidates for this volumetry. The aim of this study was to evaluate hippocampal subfields in TLE patients using ASHS as well as the old and new versions of ...

      Known for Temporal Lobe | Tle Patients | Hippocampal Subfields | Automated Subfield | Automatic Segmentation
      KOL-Index: 5949

      Neuronal intranuclear inclusion disease is a neurodegenerative disorder pathologically characterized by eosinophilic hyaline intranuclear inclusions. A high-intensity signal along the corticomedullary junction on DWI has been described as a specific MR imaging finding of the cerebrum in neuronal intranuclear inclusion disease. However, MR imaging findings of the cerebellum in neuronal intranuclear inclusion disease have not been fully evaluated. Here, we review MR imaging findings of the ...

      Known for Inclusion Disease | Neuronal Intranuclear | Imaging Features | Highintensity Signal | Corticomedullary Junction
      KOL-Index: 5855

      BACKGROUND AND PURPOSE: Recent studies suggest that the autoantibodies against adrenergic/muscarinic receptors might be one of the causes and potential markers of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). The purpose of this study was to investigate the structural network changes related to autoantibody titers against adrenergic/muscarinic receptors in ME/CFS by performing a single-subject gray matter similarity-based structural network analysis.

      METHODS: We ...

      Known for Chronic Fatigue Syndrome | Gray Matter | Betweenness Centrality | Structural Network | Characteristic Path Length
      KOL-Index: 5837

      BACKGROUND AND PURPOSE: Amygdala enlargement (AE) has been reported as an epileptogenic focus in subtypes of temporal lobe epilepsy (TLE). The purpose of this study was to investigate the clinical, morphological, and pathological characteristics of AE.

      METHODS: We retrospectively reviewed the clinical data and imaging findings of 23 TLE patients with ipsilateral AE. We performed morphological MR analyses using FreeSurfer and voxel-based morphometry (VBM) in 14 of the 23 patients and in ...

      Known for Temporal Lobe Epilepsy | Amygdala Enlargement | Cortical Dysplasia | Voxelbased Morphometry | Tle Patients

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      From the Departments of Radiology (H.F., N.Sato, Y.K., M.K., E.C., Y.S.). | Department of Radiology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan | Department of Radiology, National Center Hospital, National Cen

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