Manuella Bonmarchand

Thymidine Analogue Mutations | Stavudine Lamivudine | Viral Drug Therapy | Resistance Mutation | Hiv Reverse

Prominent publications by Manuella Bonmarchand

Low-Rate Emergence of Thymidine Analogue Mutations and Multi-Drug Resistance Mutations in the HIV-1 Reverse Transcriptase Gene in Therapy-Naive Patients Receiving Stavudine plus Lamivudine Combination

[ PUBLICATION ]

KOL Index score: 8328

OBJECTIVES: Mutations usually associated with zidovudine exposure have been observed in zidovudine-naive patients treated by stavudine in combination. These mutations were named thymidine analogue mutations (TAMs). This fact, combined with phenotypical and biochemical findings provided additional evidence for cross-resistance between zidovudine and stavudine. A recent genotypic study in naive patients receiving stavudine/didanosine combination showed emergence of TAMs and a ...

Also Ranks for: Thymidine Analogue Mutations | reverse transcriptase | naive patients | stavudine lamivudine | antiretroviral therapy

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Select a search phrase thymidine analogue mutations , thymidine analogue mutations▿

Manuella Bonmarchand:Expert Impact

Concepts for whichManuella Bonmarchandhas direct influence:Thymidine analogue mutations, Stavudine lamivudine, Viral drug therapy, Thymidine analogue, Analogue mutations, Antiretroviralnaive patients, Receiving stavudine, Resistance mutations.

Manuella Bonmarchand:KOL impact

Concepts related to the work of other authors for whichfor which Manuella Bonmarchand has influence:Resistance mutations, Virological failure, Cd4 cell count, Yxdd motif, M184v mutation, Salvage therapy, Treatment resumption.

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Departments of Virology, Infectious Diseases and Internal Medecine, Pitié-Salpêtrière Hospital, Paris, France