Rachelle L Crescenzi: Influence Statistics

Rachelle L Crescenzi

Rachelle L Crescenzi

Department of Radiology, Vanderbilt University Medical Center, Nashville, TN 37232, USA;, rachelle.crescenzi@vumc.org, (R.C.);, daniel.colvin@vumc.org, (D.C.C.) | Department ...


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Rachelle L Crescenzi: Expert Impact

Concepts for which Rachelle L Crescenzi has direct influence: Tissue sodium , Glutamate levels , Salt sensitivity , Resonance imaging , Fat content , Glucest mri , Patients lipedema .

Rachelle L Crescenzi: KOL impact

Concepts related to the work of other authors for which for which Rachelle L Crescenzi has influence: Cest mri , Chemical exchange , Saturation transfer , Resonance imaging , Disc degeneration , Tissue sodium , Rat brain .

KOL Resume for Rachelle L Crescenzi

Year
2022

Department of Radiology, Vanderbilt University Medical Center, Nashville, TN 37232, USA;, (R.C.);, (D.C.C.)

Vanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, Tennessee, USA

2021

Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA

2020

Vanderbilt University Institute of Imaging Science, Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

2019

Department of Radiology, Vanderbilt University Medical Center, Nashville, Tennessee

2018

Center for Magnetic Resonance and Optical Imaging, Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States

2017

Vanderbilt University Medical Center Department of Radiology and Radiological Science Nashville Tennessee USA

Center for Magnetic Resonance and Optical Imaging (CMROI) University of Pennsylvania Philadelphia Pennsylvania

2016

Center for Magnetic Resonance and Optical Imaging (CMROI) Department of Radiology University of Pennsylvania Philadelphia Pennsylvania

2014

Department of Biochemistry and Molecular Biophysics (BMB), University of Pennsylvania, Philadelphia, PA, USA

2013

Department of Radiology, Center for Magnetic Resonance and Optical Imaging, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States

2012

CMROI, Department of Radiology, University of Pennsylvania, Philadelphia, USA

Prominent publications by Rachelle L Crescenzi

KOL-Index: 8689 . OBJECTIVE: To test the hypothesis that tissue sodium and adipose content are elevated in patients with lipedema; if confirmed, this could establish precedence for tissue sodium and adipose content representing a discriminatory biomarker for lipedema. METHODS: Participants with lipedema (n = 10) and control (n = 11) volunteers matched for biological sex, age, BMI, and calf circumference ...
Known for Tissue Sodium | Subcutaneous Adipose | Patients Lipedema | Control Participants
KOL-Index: 8321 . Glutamate is the primary excitatory neurotransmitter in the brain, and is implicated in neurodegenerative diseases such as Alzheimer's disease (AD) and several other tauopathies. The current method for measuring glutamate in vivo is proton magnetic resonance spectroscopy ((1)H MRS), although it has poor spatial resolution and weak sensitivity to glutamate changes. In this study, we sought ...
Known for Mouse Model | Synapse Loss | Glutamate Levels | Magnetic Resonance
KOL-Index: 8016 . Glutamate chemical exchange saturation transfer (GluCEST) MRI was used to measure metabolic changes in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by mapping regional cerebral glutamate. The GluCEST contrast following MPTP treatment was correlated with 1 H-MR spectroscopy, motor function, and immunohistochemical measures. The GluCEST contrast was found to be ...
Known for Glucest Mri | Mouse Model | Dopamine Deficiency | Mptp Treatment
KOL-Index: 7115 . Glutamate Chemical Exchange Saturation Transfer (GluCEST) MRI is a recently developed technique to image glutamate. In the present study, we evaluated the reproducibility and background contamination to the GluCEST and source of the GluCEST changes in a mouse model of Parkinson’s disease. Repeated measurements in five mice demonstrated an intra-animal coefficient of variation (CV) of ...
Known for Glucest Mri | Mouse Model | Parkinson Disease | Glutamate Concentration
KOL-Index: 7046 . BACKGROUND: Breast cancer treatment-related lymphedema (BCRL) arises from a mechanical insufficiency following cancer therapies. Early BCRL detection and personalized intervention require an improved understanding of the physiological processes that initiate lymphatic impairment. Here, internal magnetic resonance imaging (MRI) measures of the tissue microenvironment were paired with ...
Known for Manual Lymphatic Drainage | Breast Cancer | Patients Bcrl | Deep Tissue
KOL-Index: 6539 . OBJECTIVE: The aim of this study is to compare tissue sodium and fat content in the upper and lower extremities of participants with lipedema versus controls using magnetic resonance imaging (MRI). METHODS: MRI was performed at 3.0 T in females with lipedema (n = 15, age = 43.2 ± 10.0 years, BMI = 30.3 ± 4.4 kg/m2 ) and controls without lipedema (n = 14, age = 42.8 ± 13.2 years, ...
Known for Tissue Sodium | Participants Lipedema | Lower Extremity | Magnetic Resonance Imaging
KOL-Index: 5858 . Tauopathies are neurodegenerative disorders characterized by abnormal intracellular aggregates of tau protein, and include Alzheimer's disease, corticobasal degeneration, frontotemporal dementia, and traumatic brain injury. Glutamate metabolism is altered in neurodegenerative disorders manifesting in higher or lower concentrations of glutamate, its transporters or receptors. Previously, ...
Known for Mouse Model | Neurodegenerative Disorders | Glutamate Levels | Synapse Density
KOL-Index: 4302 . Glutamate (Glu) is a major excitatory neurotransmitter in the brain and has been shown to decrease in the early stages of Alzheimer's disease (AD). Using a glutamate chemical (amine) exchange saturation transfer (GluCEST) method, we imaged the change in [Glu] in the APP-PS1 transgenic mouse model of AD at high spatial resolution. Compared with wild-type controls, AD mice exhibited a ...
Known for Glucest Contrast | Alzheimers Disease | Glutamate Glu | Spatial Resolution
KOL-Index: 3815 . BACKGROUND: Tissue sodium content in patients on maintenance hemodialysis (MHD) and peritoneal dialysis (PD) were previously explored using 23Sodium magnetic resonance imaging (23NaMRI). Larger studies would provide a better understanding of sodium stores in patients on dialysis as well as the factors influencing this sodium accumulation. METHODS: In this cross-sectional study, we ...
Known for Peritoneal Dialysis | Tissue Sodium | Muscle Skin | Resonance Imaging
KOL-Index: 3686 . Background: Lipedema and Dercum's disease (DD) are incompletely characterized adipose tissue diseases, and objective measures of disease profiles are needed to aid in differential diagnosis. We hypothesized that fluid properties, quantified as tissue water bioimpedance in the upper and lower extremities, differ regionally between these conditions. Methods and Results: Women (cumulative ...
Known for Patients Lipedema | Dercums Disease | Differential Diagnosis | Upper Lower Extremities
KOL-Index: 3619 . PURPOSE: To exploit the long 3.0T relaxation times and low flow velocity of lymphatic fluid to develop a noninvasive 3.0T lymphangiography sequence and evaluate its relevance in patients with lymphedema. MATERIALS AND METHODS: A 3.0T turbo-spin-echo (TSE) pulse train with long echo time (TEeffective  = 600 msec; shot-duration = 13.2 msec) and TSE-factor (TSE-factor = 90) was developed and ...
Known for Noninvasive 3 | Bcrl Participants | 94 ± | Lymphatic Drainage
KOL-Index: 3527 . PURPOSE: To quantify chemical exchange saturation transfer contrast in upper extremities of participants with lymphedema before and after standardized lymphatic mobilization therapy using correction procedures for B0 and B1 heterogeneity, and T1 relaxation. METHODS: Females with (n = 12) and without (n = 17) breast cancer treatment-related lymphedema (BCRL) matched for age and body mass ...
Known for Breast Cancer | Bcrl Participants | Cest Mri | Saturation Transfer
KOL-Index: 3466 . The purpose of this work was to quantify 3.0 T (i) T1 and T2 relaxation times of in vivo human lymph nodes (LNs) and (ii) LN relaxometry differences between healthy LNs and LNs from patients with lymphatic insufficiency secondary to breast cancer treatment-related lymphedema (BCRL). MR relaxometry was performed over bilateral axillary regions at 3.0 T in healthy female controls (105 LNs ...
Known for Magnetic Resonance | Lymph Nodes | Adult Breast | Cancer Treatment
KOL-Index: 3190 . OBJECTIVE: Lipedema is characterized by pain, fatigue, and excessive adipose tissue and sodium accumulation of the lower extremities. This case-control study aims to determine whether sodium or vascular dysfunction is present in the central nervous system. METHODS: Brain magnetic resonance imaging was performed at 3 T in patients with lipedema (n = 15) and control (n = 18) participants ...
Known for Patients Lipedema | Brain Sodium | Adipose Tissue
KOL-Index: 2405 . PurposeBreast cancer treatment-related lymphedema (BCRL) evaluation is frequently performed using portable measures of limb volume and bioimpedance asymmetry. Here quantitative magnetic resonance imaging (MRI) is applied to evaluate deep and superficial tissue impairment, in both surgical and contralateral quadrants, to test the hypothesis that BCRL impairment is frequently bilateral and ...
Known for Magnetic Resonance | Healthy Participants | Cancer Treatment | Lymphedema Bcrl

Key People For Tissue Sodium

Top KOLs in the world
#1
Friedrich Cameron Luft
blood pressure sodium intake heart rate
#2
Jens M Titze
blood pressure tissue sodium salt intake
#3
Dominik N Müller
blood pressure human renin nitric oxide
#4
Anke Dahlmann
hemodialysis patients tissue sodium liddle syndrome
#5
Kai‐Uwe Eckardt
kidney disease global outcomes cardiovascular events
#6
Michael Michael
image quality computed tomography magnetic resonance

Department of Radiology, Vanderbilt University Medical Center, Nashville, TN 37232, USA;, rachelle.crescenzi@vumc.org, (R.C.);, daniel.colvin@vumc.org, (D.C.C.) | Department of Biomedical Engineering, Vanderbilt University Medical Center, Nashville,