• Disease
  • Meibomian
  • Meibomian Glands
  • Reiko Arita

    Prominent publications by Reiko Arita

    KOL Index score: 13225

    PURPOSE: To examine the morphologic changes in meibomian glands associated with aging and gender using a novel meibography system and to assess their relation with slit-lamp findings regarding eyelid and tear film function in a normal population.

    DESIGN: Cross-sectional observation case series.

    PARTICIPANTS: Two hundred thirty-six healthy volunteers (114 men, 122 women; mean age+/-standard deviation, 41.2+/-23.1 years; range, 4-98 years).

    METHODS: The upper and lower eyelids were turned ...

    Also Ranks for: Meibomian Glands |  infrared meibography |  normal population |  schirmer test |  slit lamp
    KOL Index score: 12056

    PURPOSE: To compare clinical findings between patients with obstructive meibomian gland dysfunction (MGD) and normal controls and to propose diagnostic criteria for obstructive MGD.

    DESIGN: Cross-sectional, observational case series.

    PARTICIPANTS: Fifty-three eyes of 53 patients (18 men, 35 women; age [mean +/- standard deviation] 71.4 +/- 10.0 years) who were diagnosed with obstructive MGD and 60 eyes of 60 healthy volunteers (22 men, 38 women; 71.0 +/- 9.3 years) as a control ...

    Also Ranks for: Obstructive Mgd |  meibomian gland |  ocular symptom score |  proposed diagnostic criteria |  diagnostic techniques
    KOL Index score: 10528

    PURPOSE: Approximately 30% to 50% of contact lens (CL) wearers report dry eye symptoms. Meibomian gland dysfunction has been recognized as a possible cause of CL-related dry eye. This study investigated the influence of CL wear on the meibomian glands using a newly developed meibographic technique.

    DESIGN: Cross-sectional observational case series.

    PARTICIPANTS: Contact lens wearers (n=121; 47 men, 74 women; mean age+/-standard deviation, 31.8+/-8.0 years) and healthy volunteers (n=137; ...

    Also Ranks for: Meibomian Glands |  contact lens wear |  66 women |  dry eye symptoms |  meiboscore tear
    KOL Index score: 9843

    PURPOSE: To evaluate the efficacy and safety of intense pulsed light (IPL) combined with meibomian gland expression (MGX) for treatment of refractory meibomian gland dysfunction (MGD).

    METHODS: Ninety eyes of 45 patients were randomly assigned to receive either the combination of IPL and MGX or MGX alone (control). Each eye underwent eight treatment sessions at 3-week intervals. Parameters were evaluated before and during treatment as well as at 3-11 weeks after the last treatment ...

    Also Ranks for: Intense Pulsed Light |  meibomian gland |  ipl mgx |  llt nibut |  cfs score
    KOL Index score: 9764

    PurposeTo evaluate diagnostic criteria for obstructive meibomian gland dysfunction (MGD) using three parameters (symptom score, lid margin abnormality score, and meibomian gland morphologic change scores) for differentiating obstructive MGD from aqueous deficiency dry eye (ADDE).MethodsTwenty-five eyes of 25 patients (mean age, 66.6 years) diagnosed with obstructive MGD and 15 eyes of 15 patients (mean age, 61.3 years) diagnosed with ADDE were analyzed. Ocular symptoms were scored from 0 ...

    Also Ranks for: Meibomian Gland |  dry eye |  obstructive mgd |  aqueous deficiency |  differential diagnosis
    KOL Index score: 9590

    We report a rapid liquid chromatography/quadrupole Orbitrap Fourier transform mass spectrometry (LC-FTMS) method for identifying free fatty acids (FAs) and (O-acyl)-ω-hydroxyFAs (OAHFAs) in human meibum without derivatization. Meibum is a lipid-rich secretion and an important component of the tear film lipid layer. FAs are commonly detected by gas chromatography (GC) or GC/MS after methyl ester derivatization. We developed high-throughput lipid profiling using LC-FTMS and lipid ...

    Also Ranks for: Human Meibum |  fatty acids |  mass spectrometry |  liquid chromatography |  chromatographic separation
    KOL Index score: 9499

    ObjectiveTo examine effects of long-term topical anti-glaucoma medications on meibomian gland morphology and function and assess their relationship with slit-lamp findings.MethodsThis was a cross-sectional observational case series of 31 patients with glaucoma (mean age ± standard deviation, 65.0 ± 13.0 years; mean duration of eye drop use, 7.9 ± 6.0 years) treated with topical anti-glaucoma drugs in only one eye for more than 1 year: 13 receiving prostaglandin analogues (PGs) alone, ...

    Also Ranks for: Meibomian Glands |  topical anti |  treated eyes |  glaucoma medications |  spk score
    KOL Index score: 9378

    PURPOSE: To compare meibomian gland morphology between children and adults.

    DESIGN: Cross-sectional, observational case series.

    METHODS: In an institutional setting, healthy pediatric (n = 78, 30 boys, 48 girls; mean age ± standard deviation, 4.1 ± 3.4 years; range 1 month - 12 years) and adult (n = 25, 11 men, 14 women; 31.3 ± 4.8 years; range 24-39 years) volunteers participated in the study. A noninvasive mobile pen-shaped infrared meibography device was used to observe the meibomian ...

    Also Ranks for: Meibomian Gland Morphology |  infrared meibography |  upper lower eyelids |  glands children |  diagnostic techniques
    KOL Index score: 9359

    PURPOSE: To evaluate the efficacy of intense pulsed light (IPL) therapy combined with meibomian gland expression (MGX) for refractory meibomian gland dysfunction (MGD) in a prospective study conducted at 3 sites in Japan.

    METHODS: Patients with refractory obstructive MGD were enrolled and underwent 4 to 8 IPL-MGX treatment sessions at 3-week intervals. Clinical assessment included the Standard Patient Evaluation of Eye Dryness questionnaire; noninvasive breakup time of the tear film and ...

    Also Ranks for: Light Therapy |  meibomian gland |  intense pulsed |  multicenter study |  tear film
    KOL Index score: 9263

    PURPOSE: To compare tear film parameters as well as meibomian gland morphologic features and function among patients with meibomian gland dysfunction (MGD), those with non-Sjögren syndrome aqueous-deficient dry eye (non-SS ADDE), those with non-SS ADDE and MGD, and normal subjects.

    DESIGN: Multicenter, cross-sectional, observational case series.

    PARTICIPANTS: Forty-one eyes of 41 patients (all women; mean age ± standard deviation, 62.1±9.9 years) with non-SS ADDE, 70 eyes of 70 patients ...

    Also Ranks for: Meibomian Gland |  tear fluid |  meibum grade |  schirmers test |  nonss adde
    KOL Index score: 8662

    PURPOSE: To evaluate the effects of commercially available eyelid warming devices on ocular temperatures, tear film function, and meibomian glands in normal subjects and patients with meibomian gland dysfunction (MGD).

    METHODS: Ten healthy volunteers were enrolled to evaluate the effects of a single warming and of repeated warming for 2 weeks. Ten MGD patients were enrolled for evaluation of repeated warming over 1 month. Two non-wet (Azuki no Chikara, Eye Hot R) and three wet (hot ...

    Also Ranks for: Meibomian Gland Dysfunction |  tear film |  normal subjects |  eyelid warming |  mgd patients
    KOL Index score: 8532

    PURPOSE: To evaluate the prevalence and risk factors of and the relationship between meibomian gland dysfunction (MGD) and dry eye (DE) in Japan.

    DESIGN: A population-based cross-sectional study.

    METHODS: Participants filled in questionnaires regarding ocular symptoms, systemic diseases, and lifestyle factors. Meibomian gland-related parameters and tear film-related parameters were evaluated. Risk factors for MGD and DE were analyzed by using univariate and multivariate logistic ...

    Also Ranks for: Dry Eye |  meibomian gland dysfunction |  prevalence mgd |  takushima study |  ocular symptoms
    KOL Index score: 7932

    PURPOSE: To observe the morphology of the corneal cells and corneal nerve fibers in patients with type IV or V hereditary sensory and autonomic neuropathy (HSAN) by in vivo confocal microscopy and elucidate the mechanism leading to the loss of corneal sensation in this disease.

    METHODS: In vivo confocal microscopy was performed on the central cornea of the right eye in 3 patients with HSAN (ages 17, 20, and 32 years), and their corneal morphology was compared with that of 3 healthy ...

    Also Ranks for: Vivo Confocal Microscopy |  hereditary sensory |  autonomic neuropathy |  corneal sensation |  patients hsan
    KOL Index score: 7719

    PURPOSE: To observe morphologic changes of meibomian glands in patients with and without perennial allergic conjunctivitis (AC) and to assess the relation between morphologic changes of the meibomian glands of both eyelids and tear film parameters.

    METHODS: In this study, 55 eyes of 55 patients with perennial AC and 47 eyes of 47 healthy volunteers as controls were included. The following tests were performed: a slit-lamp examination, measurement of tear film breakup time, grading of ...

    Also Ranks for: Meibomian Gland |  perennial allergic |  meibography score |  distortion patients |  breakup time
    KOL Index score: 7679

    PURPOSE: To evaluate whether the amount of meibum and its viscosity change after intraductal meibomian gland probing in patients with refractory obstructive meibomian gland dysfunction (o-MGD).

    METHODS: Six lid margins of 3 patients with refractory o-MGD underwent intraductal meibomian gland probing. Meibum and the clinical outcome were evaluated before the procedure and at a 1-month postoperative visit. Meibum was quantified with a Meibometer, and its viscosity (Shimazaki grade) was ...

    Also Ranks for: Meibomian Gland |  tear breakup time |  ocular symptoms |  mgd meibum |  eyelid diseases


    Reiko Arita: Influence Statistics

    Sample of concepts for which Reiko Arita is among the top experts in the world.
    Concept World rank
    adde mgx #1
    function meibomian glands #1
    llt diquafosol #1
    baseline mgd worsening #1
    meibographic modalities #1
    dysfunction evaluate #1
    meibography new insights #1
    noncontact meibography #1
    distinguish mgd #1
    mgd mgdrelated disorders #1
    cataract surgery mgd #1
    eye accompanied #1
    glands scored #1
    mgx conjunctiva cornea #1
    gland dysfunction #1
    meibomian gland dysfunction #1
    mgd ocular symptoms #1
    eye hot #1
    dr1α tear #1
    condition tear #1
    chalazion sebaceous carcinoma #1
    extent mgd #1
    hiradotakushima study #1
    meibum grade males #1
    major causative condition #1
    mgd 90 #1
    plugging meibomian #1
    tzu dogs #1
    meibography meiboscore #1
    upper lower eyelids #1
    90 diquafosol administration #1
    32 weeks adjusted #1
    confocal tears #1
    slight enlargement proliferation #1
    glandular atresia #1
    meiboscore correlated #1

    Key People For Meibomian Glands

    Top KOLs in the world
    Anthony J Bron
    dry eye tear film ocular surface
    Tsubota TSUBOTA
    dry eye ocular surface lacrimal gland
    Reiko Arita
    meibomian glands dry eye tear film
    David A Sullivan
    gene expression meibomian gland secretory component
    Shiro Amano
    allergic conjunctivitis meibomian glands corneal neovascularization
    Kelly Kinney Nichols
    dry eye tear film meibomian gland dysfunction

    Reiko Arita:Expert Impact

    Concepts for whichReiko Aritahas direct influence:Meibomian glands,  Meibomian gland,  Meibomian gland dysfunction,  Dry eye,  Tear film,  Meibomian gland morphology,  Ocular surface,  Normal subjects.

    Reiko Arita:KOL impact

    Concepts related to the work of other authors for whichfor which Reiko Arita has influence:Dry eye,  Meibomian gland,  Ocular surface,  Tear film,  Contact lens,  Cataract surgery,  Schirmer test.



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    Department of Ophthalmology, Itoh Clinic, 626-11 Minami-Nakano, Minumaku, Saitama 337-0042, Japan | Lid and Meibomian Gland Working Group, 626-11 Minami-Nakano, Minumaku, Saitama 337-0042, Japan;, motoko326@gmail.com, (M.K.);, fshima3271@gmail.com, (