• Disease
  • Endoscopic
  • Endoscopic Endonasal
  • Paolo Cappabianca

    Prominent publications by Paolo Cappabianca

    KOL Index score: 14884

    OBJECTIVE: This prospective randomized study evaluated the efficacy and safety of octreotide LAR vs. surgery in newly diagnosed acromegalic patients.

    METHODS: Totally 104 male and female patients were enrolled in a 50-week, exploratory, open-label and randomized study. Eligible patients were randomized to receive either octreotide LAR 20 mg every 28 days or to undergo surgery. Efficacy was assessed by changes in mean GH and IGF-I serum concentrations, at weeks 12, 24 and 48. Tumour ...

    Also Ranks for: Octreotide Lar |  surgery patients |  acromegaly efficacy |  growth hormone |  tumour volume
    KOL Index score: 13338

    BACKGROUND: Whether the withdrawal of treatment in patients with nontumoral hyperprolactinemia, microprolactinomas, or macroprolactinomas is safe and effective has been unclear. We performed an observational, prospective study of cabergoline (a dopamine-receptor agonist) withdrawal in such patients.

    METHODS: The study population included 200 patients--25 patients with nontumoral hyperprolactinemia, 105 with microprolactinomas, and 70 with macroprolactinomas. Withdrawal of cabergoline was ...

    Also Ranks for: Withdrawal Patients |  macroprolactinomas microprolactinomas |  prolactin levels |  time recurrence |  cabergoline therapy
    KOL Index score: 13300

    OBJECT: The management of recurrent or residual craniopharyngiomas remains controversial. Although possible, revision surgery is more challenging than primary surgery, and more often results in incomplete resection and an increased risk of death and complications. The extended (also called expanded) endoscopic endonasal transsphenoidal approach through the planum sphenoidale has been proposed over the past decade as an alternative surgical route for removal of various suprasellar tumors ...

    Also Ranks for: Endoscopic Endonasal |  recurrent craniopharyngiomas |  transsphenoidal approach |  local neoplasm |  craniopharyngioma female humans
    KOL Index score: 12192

    The evolution of the endoscopic endonasal transsphenoidal technique, which was initially reserved only for sellar lesions through the sphenoid sinus cavity, has lead in the last decades to a progressive possibility to access the skull base from the nose. This route allows midline access and visibility to the suprasellar, retrosellar and parasellar space while obviating brain retraction, and makes possible to treat transsphenoidally a variety of relatively small midline skull base and ...

    Also Ranks for: Skull Base |  extended endoscopic |  transsphenoidal surgery |  parasellar lesions |  endonasal approach
    KOL Index score: 11898

    The effect of surgery alone or followed by radiotherapy in recovering visual abnormalities, debulking tumor mass and restoring hormone impairments was evaluated in 84 patients with clinically nonfunctioning pituitary adenomas (NFPA) subjected to 1–10 yr follow-up. All patients underwent surgery via transsphenoidal (in 69) or transcranic-pterional approach (in 15). Radiotherapy was performed after surgery in 59 of 72 patients with incomplete tumor removal. The assessment of pituitary ...

    Also Ranks for: Surgery Radiotherapy |  pituitary function |  prevalence hypopituitarism |  tumor regrowth |  visual disturbances
    KOL Index score: 11833

    OBJECT: The extended transnasal approach, a recent surgical advancements for the ventral skull base, allows excellent midline access to and visibility of the anterior cranial fossa, which was previously thought to be approachable only via a transcranial route. The extended transnasal approach allows early decompression of the optic canals, obviates the need for brain retraction, and reduces neurovascular manipulation.

    METHODS: Between 2004 and 2007, 11 consecutive patients underwent ...

    Also Ranks for: Cranial Fossa |  ogm tsm |  endoscopic transnasal resection |  1 patient |  brain retraction
    KOL Index score: 11779

    The outcome of 24 months of cabergoline treatment on prolactin (PRL) normalization, tumor shrinkage, restoration of pituitary function, and semen alterations was prospectively investigated in 41 men with macro- (age 17-70 yr) and 10 with microprolactinoma (age 18-53 yr). Fifty-one age-matched men served as controls for semen analysis. At study entry, of the 41 patients with macroprolactinoma, 17 (41.4%) had visual field defects, 14 (34.1%) had headache, eight (19.5%) had galactorrhea, 22 ...

    Also Ranks for: Cabergoline Treatment |  prolactin levels |  tumor mass |  magnetic resonance |  visual field defects
    KOL Index score: 11469

    BACKGROUND: Fibrin sealants are widely used in neurosurgery to seal the suture line, provide watertight closure, and prevent cerebrospinal fluid leaks. The aim of this systematic review is to summarize the current efficacy and safety literature of fibrin sealants in dura sealing and the prevention/treatment of cerebrospinal fluid leaks.

    METHODS: A comprehensive electronic literature search was run in the following databases: Cochrane Database of Systematic Reviews, Cochrane Central ...

    Also Ranks for: Fibrin Sealants |  dura sealing |  systematic literature review |  cerebrospinal fluid leaks |  neurosurgical procedures
    KOL Index score: 11434

    BACKGROUND: Remission rates of 76, 69.5 and 64.3% have been reported in patients with nontumoural hyperprolactinaemia (NTH), microprolactinoma and macroprolactinoma, respectively, 2-5 years after cabergoline (CAB) withdrawal.

    OBJECTIVE: To report the estimated recurrence rate at 24-96 months after CAB withdrawal and indicate predictors of disease remission.

    DESIGN: Observational, analytical, prospective.

    PATIENTS: Of 381 previously untreated de novo patients with hyperprolactinaemia, 221 ...

    Also Ranks for: Patients Hyperprolactinaemia |  cab withdrawal |  predictors remission |  prl levels |  dopamine agonists
    KOL Index score: 11267

    CONTEXT: Surgery is a cornerstone in the treatment of acromegaly, but its efficacy in large, invasive tumors is scant.

    OBJECTIVE: The objective of this study was to investigate whether partial surgical removal of GH-secreting pituitary tumors enhances the response rate to somatostatin analogs (SSA; sc octreotide, slow-release octreotide, and lanreotide).

    DESIGN: This was a multicenter, open, retrospective study.

    SETTING: The study was performed at university hospitals.


    Also Ranks for: Somatostatin Analogs |  growth hormone |  surgical removal |  gh levels |  acromegaly surgery
    KOL Index score: 11262

    OBJECT: The midline skull base is an anatomical area that extends from the anterior limit of the cranial fossa down to the anterior border of the foramen magnum. Resection of lesions involving this area requires a variety of innovative skull base approaches. These include anterior, anterolateral, and posterolateral routes, performed either alone or in combination, and resection via these routes often requires extensive neurovascular manipulation. The goals in this study were to define ...

    Also Ranks for: Midline Skull Base |  anatomical study |  clinical considerations |  endoscopic endonasal surgery |  dura mater
    KOL Index score: 11191

    OBJECTIVE: To determine, in patients undergoing sellar repair after endoscopic endonasal transsphenoidal surgery, the clinical efficacy of a combination of fibrin sealant/collagen fleece compared to the use of fibrin sealant or collagen fleece alone, in preventing CSF-related (cerebrospinal fluid) postoperative complications.

    METHODS: From a retrospective analysis of our series of 242 consecutive endoscopic transsphenoidal procedures, in 56 out of the 90 cases in which the sella had been ...

    Also Ranks for: Fibrin Sealant |  collagen fleece |  sellar repair |  postoperative lumbar drainage |  endonasal transsphenoidal


    Paolo Cappabianca: Influence Statistics

    Sample of concepts for which Paolo Cappabianca is among the top experts in the world.
    Concept World rank
    surgical anatomy combining #1
    βcatenin recurrence #1
    remifentanil 10 ml1 #1
    fibreoptic procedure #1
    radical resection years #1
    transgressing respiratory mucosa #1
    endoscopy humans #1
    2 doses patient #1
    paramount importanceβcatenin #1
    transorbital endoscopic view #1
    official classification systems #1
    bone ridge triangle #1
    başak #1
    route nose #1
    possibility anatomical studies #1
    5 postprocedural complications #1
    endoscopic equipment #1
    patients transsphenoidal #1
    squamous epithelial remnants #1
    transcranial option #1
    pituitary lesions tumors #1
    relevant anatomy #1
    tumours brain metastasis #1
    invasive craniotomy cases #1
    transplanum approach #1
    endoscopes pituitary area #1
    procedure illustrative cases #1
    film fibrin glue #1
    suprasellar lesions #1
    weak sellar barrier #1
    new advanced devices #1
    brain convexity meningiomas #1
    effectiveness wide vision #1
    preservation ligamentum flavum #1
    internal visualization cavities #1
    fresh cadaver heads #1
    endoscopy transsphenoidal surgery #1
    persistent fearing #1
    principal negative aspect #1
    standard transsphenoidal surgery #1
    microsurgery nasal #1
    horizontal plane interference #1
    anatomical studies surgery #1
    movement realistic view #1
    pregnancy meningioma #1
    sole drainage #1
    neurosurgery pregnancy #1
    lateral approach chamaleontic #1
    cavity pituitary #1
    cases routine autopsies #1

    Key People For Endoscopic Endonasal

    Top KOLs in the world
    Carl H Snyderman
    skull base endoscopic endonasal nasoseptal flap
    Ricardo Luis Carrau
    skull base endoscopic endonasal nasoseptal flap
    Paul A Gardner
    skull base endoscopic endonasal nasoseptal flap
    Amin Bardai Kassam
    skull base nasoseptal flap vidian canal
    Daniel Monte Serrat Prevedello
    skull base endoscopic endonasal nasoseptal flap
    Paolo Cappabianca
    endoscopic endonasal skull base pituitary adenomas

    Paolo Cappabianca:Expert Impact

    Concepts for whichPaolo Cappabiancahas direct influence:Endoscopic endonasal,  Skull base,  Pituitary adenomas,  Transsphenoidal surgery,  Sellar barrier,  Fibrin sealants,  Anatomical study,  Sphenoid sinus.

    Paolo Cappabianca:KOL impact

    Concepts related to the work of other authors for whichfor which Paolo Cappabianca has influence:Pituitary adenomas,  Skull base,  Transsphenoidal surgery,  Cavernous sinus,  Endoscopic endonasal,  Dopamine agonists,  Growth hormone.



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    Division of Neurosurgery, Department of Neurosciences and Reproductive and Odontostomatological Sciences, Università degli Studi di Napoli Federico II, 80131 Naples, Italy. | Department of Neurosciences and Reproductive and Odontostomatological Scien