• Disease
  • Tuberous
  • Tuberous Sclerosis
  • Pietro Sciacca

    Prominent publications by Pietro Sciacca

    KOL Index score: 11283

    BACKGROUND: Rhabdomyomas are the most common type of cardiac tumors in children. Anatomically, they can be considered as hamartomas. They are usually randomly diagnosed antenatally or postnatally sometimes presenting in the neonatal period with haemodynamic compromise or severe arrhythmias although most neonatal cases remain asymptomatic. Typically rhabdomyomas are multiple lesions and usually regress spontaneously but are often associated with tuberous sclerosis complex (TSC), an ...

    Also Ranks for: Tuberous Sclerosis |  cardiac tumors |  33 cases |  common type |  complex 2
    KOL Index score: 8929

    BACKGROUND: Sustained Lung Inflation (SLI) is a maneuver of lung recruitment in preterm newborns at birth that can facilitate the achieving of larger inflation volumes, leading to the clearance of lung fluid and formation of functional residual capacity (FRC).

    AIM: To investigate if Sustained Lung Inflation (SLI) reduces the need of invasive procedures and iatrogenic risks.

    STUDY DESIGN: 78 newborns (gestational age≤34 weeks, weighing≤2000 g) who didn't breathe adequately at birth and ...

    Also Ranks for: Sustained Lung Inflation |  preterm infants |  lung recruitment |  distress syndrome |  newborn infant
    KOL Index score: 7349

    Globin gene mapping analyses of DNA from numerous Black babies, and from newborns from Sardinia, Sicily, Turkey, and Spain have identified the following: A high incidence of alpha-thalassemia-2 heterozygotes among Black babies with less than 1% Hb Bart's at birth and a high incidence of alpha-thalassemia-2 among Sardinians, but not among Sicilian, Turkish, and Spanish babies. A relatively high incidence of zeta-thalassemia was present among Black babies only, while triplicated zeta was ...

    Also Ranks for: Globin Gene |  psi zeta |  hb bart |  spain thalassemia |  blood samples
    KOL Index score: 5033

    BACKGROUND: Cardiovascular involvement in Cystic Fibrosis (CF) is a not rare condition, although the prevalence of subclinical pulmonary hypertension (PH) and cardiac dysfunction is not known in the early stages of CF progression. The aim of our study was to assess cardiac involvement in children and adults affected by cystic fibrosis compared with healthy subjects of same age using echocardiography.

    METHODS: Fifty-five patients, 25 adults and 30 children completed the study. We assessed ...

    Also Ranks for: Cystic Fibrosis |  heart involvement |  pulmonary artery |  stroke volume |  function patients
    KOL Index score: 4211

    BACKGROUND: Adolescents with type 1 diabetes and obesity present higher cardiovascular risk and ambulatory blood pressure measurements (ABPM) has been shown to predict vascular events, especially by identifying the nondipper status. The aim of our observational cross-sectional study conducted in adolescents with type 1 diabetes, overweight subjects and healthy controls was to assess mean blood pressure parameters to identify subclinical cardiovascular risk.

    METHODS: The study included ...

    Also Ranks for: Type 1 |  blood pressure |  studies diabetes |  cardiovascular risk |  24 systolic
    KOL Index score: 3354

    It is well known that the natural history of chronic heart failure (CHF),regardless of age and aetiology,is characterized by progressive cardiac dysfunction refractory to conventional cardiokinetic, diuretic and peripheral vasodilator therapy. Several previous studies, both in animals and humans, showed that the key pathogenetic element of CHF negative clinical evolution is constituted by myocardial remodeling. This is a complex pathologic process of ultrastructural rearrangement of the ...

    Also Ranks for: Chronic Heart Failure |  gene therapy |  biomechanical stress |  cardiomyocytes hypertrophy |  animals apoptosis
    KOL Index score: 2689

    We described two sibs born to consanguineous Sicilian parents who died of severe congenital heart malformation. Both had dextrocardia; however, only the girl had situs viscerum inversus. At necropsy she was found to have a right spleen and right pulmonary isomerism (three lobes in each lung, as commonly found in the asplenia syndrome). This observation, together with other literature reports, suggest that isolated dextrocardia, situs viscerum inversus, and the asplenia-polysplenia ...

    Also Ranks for: Asplenia Syndrome |  congenital humans infant |  literature reports |  dextrocardia situs |  publication abnormalities
    KOL Index score: 2113

    BACKGROUND: Kawasaki disease is a multi-system vasculitis which usually occurs in children under 5 years of age. In infants under three months of age, it is very rare and usually associated with a high incidence of incomplete or atypical forms, often unresponsive to treatment. This condition increases the risk of cardiovascular complications such as coronary artery aneurysms.

    CASE PRESENTATION: We describe a 3-month-old infant who developed early and severe aneurysms in three coronary ...

    Also Ranks for: Kawasaki Disease |  3 months age |  young infants |  coronary arteries |  mucocutaneous lymph
    KOL Index score: 1994

    BACKGROUND: Kawasaki disease (KD) is a generalized systemic vasculitis of unknown etiology involving medium and small size blood vessels, particularly the coronary arteries. In these vessels a progressive stenosis may result from active remodeling with an intimal proliferation and neoangiogenesis. The aim of our study was to assess, by using high-resolution transthoracic 2D Echocardiography, if subjects with a previous diagnosis of Kawasaki disease after several years show a coronary ...

    Also Ranks for: Kawasaki Disease |  acute phase |  mucocutaneous lymph |  node syndrome |  predictive tests


    Pietro Sciacca: Influence Statistics

    Sample of concepts for which Pietro Sciacca is among the top experts in the world.
    Concept World rank
    rhabdomyomas newborn #4
    sli infants #5
    ostium secundum type #12
    rhabdomyomas tuberous #13
    observation literature reports #13
    multiple rhabdomyomas #27
    zeta psi #31
    deletion zeta #34
    psi zeta #35
    spain thalassemia #47
    sticklers syndrome #48
    inflation sli #48
    thalassemia rare #50
    mapping spain #50
    association tuberous #52
    sustained lung inflation #54
    function celiac #59
    atopic risk #80
    rearrangement globins #90
    pregnancy rhabdomyoma #91
    sli female humans #99

    Key People For Tuberous Sclerosis

    Top KOLs in the world
    David J Kwiatkowski
    tuberous sclerosis lung cancer mammalian target
    Sergiusz Jóźwiak
    tuberous sclerosis patients tsc giant cell
    Elizabeth Petri Henske
    tuberous sclerosis mammalian target tsc2deficient cells
    Ewell Steve Roach
    tuberous sclerosis complex weber syndrome intracranial hypertension
    Hope A Northrup
    tuberous sclerosis complex spina bifida infantile spasms
    David Neal Franz
    tuberous sclerosis patients tsc mammalian target

    Pietro Sciacca:Expert Impact

    Concepts for whichPietro Sciaccahas direct influence:Tuberous sclerosis,  Kawasaki disease,  Cystic fibrosis,  Tuberous sclerosis complex,  Cardiac involvement,  Sustained lung inflation,  Celiac disease,  Heart involvement.

    Pietro Sciacca:KOL impact

    Concepts related to the work of other authors for whichfor which Pietro Sciacca has influence:Cystic fibrosis,  Tuberous sclerosis complex,  Sustained inflation,  Food allergy,  Infant formula,  Type 1 diabetes,  Spinal muscular atrophy.



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    Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy | Pediatric Cardiology, AOU Policlinico-Vittorio Emanuele, via Santa Sofia 78, 95123 Catania, Italy | University of Arizona, Division of Health, Promotion Science