• Disease
  • Endoprosthetic
  • Endoprosthetic Reconstruction
  • Timothy Damron

    Prominent publications by Timothy Damron

    KOL Index score: 5157

    INTRODUCTION: Limb salvage with endoprosthetic reconstruction is the standard of care for the management of lower-extremity bone tumours in skeletally mature patients. The risk of deep postoperative infection in these procedures is high and the outcomes can be devastating. The most effective prophylactic antibiotic regimen remains unknown, and current clinical practice is highly varied. This trial will evaluate the effect of varying postoperative prophylactic antibiotic regimens on the ...

    Also Ranks for: Tumour Surgery |  endoprosthetic reconstruction |  prophylactic antibiotic regimens |  controlled study |  deep infection
    KOL Index score: 2646

    BACKGROUND: Limb salvage with endoprosthetic reconstruction is the current standard practice for the surgical management of lower extremity bone tumors in skeletally mature patients and typically includes tumor resection followed by the functional limb reconstruction with modular metallic and polyethylene endoprosthetic implants. However, owing to the complexity and length of these procedures, as well as the immunocompromised nature of patients treated with chemotherapy, the risk of ...

    Also Ranks for: Endoprosthetic Reconstruction |  1day regimen |  bone tumor |  surgical site infection |  5 day
    KOL Index score: 2014

    Importance: The use of perioperative, prophylactic, intravenous antibiotics is standard practice to reduce the risk of surgical site infection after oncologic resection and complex endoprosthetic reconstruction for lower extremity bone tumors. However, evidence guiding the duration of prophylactic treatment remains limited.

    Objective: To assess the effect of a 5-day regimen of postoperative, prophylactic, intravenous antibiotics compared with a 1-day regimen on the rate of surgical site ...

    Also Ranks for: Endoprosthetic Reconstruction |  bone tumors |  lower extremity |  surgical site infections |  antibiotic regimens


    Timothy Damron: Influence Statistics

    Sample of concepts for which Timothy Damron is among the top experts in the world.
    Concept World rank
    nct01479283 #17
    sarcoma invaded #17
    plan parity #25
    salvage parity #25
    1day regimen article #25
    endoprosthetic reconstruction article #25
    postoperative antibiotics risk #29
    immunocompromised nature #33
    salvage endoprosthetic #34
    excision endoprosthetic #35
    parity trial #41
    parity center #44
    surgery parity #47
    regimen article #51
    endoprosthetic replacements #51
    48 clinical sites #59
    95 antibioticrelated complications #59
    alternative antibiotic regimens #65
    regimens tumour #66
    prophylactic antibiotic regimens #67
    clinical superiority trial #71
    antibioticrelated complications #72
    1day regimen #74
    oligometastatic bone #77
    infection oncologic #81
    superiority 5 #83

    Key People For Endoprosthetic Reconstruction

    Top KOLs in the world
    Robert John Grimer
    endoprosthetic replacement proximal tibia limb salvage
    John H Healey
    ewing sarcoma local control limb salvage
    Simon R Carter
    endoprosthetic replacement proximal femur limb salvage
    Roger M Tillman
    endoprosthetic replacement proximal femur limb salvage
    Rainer Ingo Kotz
    flat foot patients osteosarcoma neoadjuvant chemotherapy
    Jeffrey John Eckardt
    endoprosthetic reconstruction limb salvage proximal tibia

    Timothy Damron:Expert Impact

    Concepts for whichTimothy Damronhas direct influence:Endoprosthetic reconstruction,  Prophylactic antibiotic regimens,  1day regimen,  5day regimen,  Tumor resection,  Tumor surgery,  Tumour surgery,  Antibiotic regimens.

    Timothy Damron:KOL impact

    Concepts related to the work of other authors for whichfor which Timothy Damron has influence:Orthopaedic oncology,  Endoprosthetic reconstruction,  Surgical site infection,  Bone tumors,  Tumor resection,  Topical vancomycin,  Sacral chordomas.



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    The Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY) Investigators | Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, L8S 4L8 ON Canada | Juravinski Hospital and Cancer Centre, Hamilton Health Scien