• Disease
  • New
  • New Zealand
  • John Simpson

    Prominent publications by John Simpson

    KOL Index score: 19074

    BACKGROUND: Many patients with COVID-19 have been treated with plasma containing anti-SARS-CoV-2 antibodies. We aimed to evaluate the safety and efficacy of convalescent plasma therapy in patients admitted to hospital with COVID-19.

    METHODS: This randomised, controlled, open-label, platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]) is assessing several possible treatments in patients hospitalised with COVID-19 in the UK. The trial is underway at 177 NHS hospitals from ...

    Also Ranks for: Convalescent Plasma |  patients usual |  platform trial |  hospital covid19 |  rate ratio
    KOL Index score: 12726

    Importance: The evidence for benefit of convalescent plasma for critically ill patients with COVID-19 is inconclusive.

    Objective: To determine whether convalescent plasma would improve outcomes for critically ill adults with COVID-19.

    Design, Setting, and Participants: The ongoing Randomized, Embedded, Multifactorial, Adaptive Platform Trial for Community-Acquired Pneumonia (REMAP-CAP) enrolled and randomized 4763 adults with suspected or confirmed COVID-19 between March 9, 2020, and ...

    Also Ranks for: Convalescent Plasma |  organ support |  posterior probability |  critically patients |  2 units
    KOL Index score: 10571

    Since chemotherapy for metastatic breast cancer is not curative, consideration of the quality of life is important in selecting a treatment regimen. We conducted a randomized trial comparing continuous chemotherapy, administered until disease progression was evident, with intermittent therapy, whereby treatment was stopped after three cycles and then repeated for three more cycles only when there was evidence of disease progression. Each approach was tested with doxorubicin combined with ...

    Also Ranks for: Life Quality Life |  advanced breast cancer |  continuous chemotherapy |  intermittent therapy |  physical wellbeing
    KOL Index score: 10508

    Abstract We have begun a long-term ecological research project to address questions about the impact of multiple disturbances on the species richness of communities and whether multiple disturbances are additive or interactive. A protected water catchment area was chosen, which is subjected to fires, sand mining and clearing, and for which detailed records are available. The study area, at Tomago (32°52′S, 151°45′E), has forest, woodland, shrubland and swamp on a sand substrate, with the ...

    Also Ranks for: Sand Mining |  multiple disturbances |  mined sites |  vegetation structure |  species richness
    KOL Index score: 9603

    OBJECTIVE: To explore the opinions of surgeons about the NHMRC clinical practice guidelines for the management of early breast cancer (the Guidelines) and their views about and use of the accompanying Consumer's guide.

    DESIGN: Cross-sectional telephone survey.

    PARTICIPANTS AND SETTING: Surgeons throughout Australia who manage breast cancer, designated as "breast" or "general" (members or non-members of the Royal Australasian College of Surgeons' Section of Breast Surgery) and "urban" or ...

    Also Ranks for: Practice Guidelines |  breast cancer |  nhmrc clinical |  medical surveys |  royal australasian college
    KOL Index score: 8790

    BACKGROUND: The optimal control of communicable diseases requires accurate information on incubation periods, periods of infectiousness and the effectiveness of exclusion. We collected the available evidence for a wide range of infections and infestations and produced evidence-based guidelines for their control in schools and preschools.

    METHODS: A thorough MEDLINE literature search was conducted on the incubation period, period of infectiousness and effectiveness of exclusion for 41 ...

    Also Ranks for: Communicable Diseases |  incubation periods |  guidelines exclusion |  infections child |  disease control
    KOL Index score: 8734

    BACKGROUND: Irbesartan, a long acting selective angiotensin-1 receptor inhibitor, in Marfan syndrome might reduce aortic dilatation, which is associated with dissection and rupture. We aimed to determine the effects of irbesartan on the rate of aortic dilatation in children and adults with Marfan syndrome.

    METHODS: We did a placebo-controlled, double-blind randomised trial at 22 centres in the UK. Individuals aged 6-40 years with clinically confirmed Marfan syndrome were eligible for ...

    Also Ranks for: Marfan Syndrome |  aortic dilatation |  placebo difference |  receptor blockers |  randomised trial
    KOL Index score: 7667

    INTRODUCTION: The prevalence of azole resistance in C parapsilosis is very low in most parts of the world. However, South Africa has reported an exceptionally high prevalence of azole resistance in C parapsilosis strains isolated from candidaemia cases. We aimed to determine the possible molecular mechanisms of fluconazole resistance in C parapsilosis isolates obtained through surveillance at a large neonatal unit at a South African academic hospital.

    METHODS: We sequenced the ERG11 and ...

    Also Ranks for: Erg11 Gene |  y132f substitution |  candida parapsilosis |  azole resistance |  susceptible isolates
    KOL Index score: 5981

    We analyse the relationship between board structure and firm performance in family-controlled firms using a sample of Indonesian non-financial companies. We find that the share of independent directors on the board has an insignificant relationship with firm performance. We suspect that the result is driven by the lack of institutional reforms in relation to the appointment of independent directors. Our analysis shows strong empirical support for the proposition that family control ...

    Also Ranks for: Firm Performance |  independent directors |  board structure |  evidence indonesia
    KOL Index score: 5340

    Increased attention is now being focused on developing new technologies to cure atrial fibrillation using catheter ablation techniques. The performance of a MAZE-type procedure using standard catheter ablation technologies is arduous and is associated with an unacceptable risk of complications. The Guidant Heart Rhythm Technologies Linear Ablation System was developed to create long transmural linear lesions. Unique features of this system include the availability of different preshaped ...

    Also Ranks for: Atrial Fibrillation |  catheter ablation |  duty cycle |  topic treatment |  linear lesions
    KOL Index score: 5209

    The Independent Nuclear State: The United States, Britain and the Military Atom is a chronological account and overview of the 40-year history of British military research, development and production work in atomic energy. The United Kingdom's efforts in this field have always had close links with equivalent activities in the United States, and have often been conducted on a mutually co-operative basis. Through its description of these secret Anglo-American interactions, this study ...

    Also Ranks for: United States |  nuclear weapons |  fissile material |  british government |  anglo relations
    KOL Index score: 4852

    Most academic discussion on the role of language in education in sub-Saharan Africa (SSA) supports the extended use of African languages as media of instruction (MoI), while most practice preserves a monolingual role for European languages. Many ministries of education maintain the belief that African languages are not appropriate as MoIs beyond the early years. In African countries in which English is the MoI, many learners in primary school and beyond do not have sufficient ability in ...

    Also Ranks for: Saharan Africa |  language education |  primary school |  english medium |  textbook design
    KOL Index score: 4768

    PURPOSE: To dynamically quantify pancreatic perfusion and flow within the arteries supplying the pancreas in response to secretin stimulation.

    MATERIALS AND METHODS: Twelve healthy male subjects were scanned at 1.5T with arterial spin labeling to measure tissue perfusion and phase contrast magnetic resonance imaging (MRI) to measure vessel flow. Superior mesenteric (SMA), gastroduodenal (GDA), common hepatic (HA), and splenic (SA) arterial flow and pancreatic perfusion were serially ...

    Also Ranks for: Blood Flow |  pancreatic perfusion |  secretin stimulation |  arterial spin |  imaging male
    KOL Index score: 4679

    Abstract Due to increased hydrocarbon demand and technological advances, production from heavy oil fields in the United Kingdom Continental Shelf (UKCS) has become possible over the past 10 years. Despite substantial reserves in the UKCS with crudes less than 20° API, most of the activity has been confined to exploration and appraisal drilling. The main reason for the restricted activity has been the high uncertainty of the reservoir and fluid properties. Operational complexities ...

    Also Ranks for: Heavy Oil |  bentley field |  lessons learned |  technical challenges |  fluid mobility


    John Simpson: Influence Statistics

    Sample of concepts for which John Simpson is among the top experts in the world.
    Concept World rank
    distant hospitals conclusion #1
    new zealand hours #1
    contestable zip codes #1
    sign exclusive #1
    surgeons new zealand #1
    sand mined #1
    series interlinked pieces #1
    bentley field #1
    edition oed #1
    review conference #1
    indicators dynamic models #1
    2003 prepcom session #1
    npt review #1
    hospitals unprofitable #1
    regulation risk ratings #1
    cleared mined #1
    states weapon #1
    mutually cooperative basis #1
    britain nuclear #1
    increase unprofitable #1
    zealand surgeons #1
    2003 prepcom #1
    dictionary philological society #1
    regime intensive #1
    article courts #1
    75th anniversary completion #1
    intensive npt #1
    absence scale economies #1
    oxford english #1
    cleared mined sites #1
    society june #1
    heavy oil testing #1
    military atom #1
    oxford english dictionary #1
    hospitals price increase #1
    surgical services future #1
    political indicators #1
    work hours limitations #1
    security assurances #1
    british polaris #1
    contestable zip #1
    courts hospitals #1
    merger retrospectives #1
    dictionary today #1
    price increase article #1
    united kingdoms efforts #1
    annual output figures #1
    452 73 #1
    english dictionary #1

    Key People For New Zealand

    Top KOLs in the world
    Matt S McGlone
    new zealand south island glacial maximum
    Kelvin R Berryman
    new zealand north island alpine fault
    Nick Mortimer
    new zealand otago schist south fiji basin
    Rupert Sutherland
    new zealand alpine fault south westland
    Brent V Alloway
    new zealand wanganui basin north island
    Bruce F Houghton
    new zealand taupo volcanic zone kīlauea volcano

    John Simpson:Expert Impact

    Concepts for whichJohn Simpsonhas direct influence:New zealand,  Convalescent plasma,  Firm performance,  Diverticular disease,  Nonprofit hospitals,  Exclusive contracts,  Independent directors,  Marfan syndrome.

    John Simpson:KOL impact

    Concepts related to the work of other authors for whichfor which John Simpson has influence:Convalescent plasma,  Metastatic breast cancer,  Quality life,  Meralgia paresthetica,  Atrial fibrillation,  Gender differences,  Influenza virus.



    Is this your profile? manage_accounts Claim your profile content_copy Copy URL code Embed Link to your profile

    Calvary Mater Newcastle, Newcastle, Australia | Director of Paediatric Echocardiography, the Evelina Children's Hospital Guy's and St Thomas' NHS Foundation Trust, London, UK | Newcastle upon Tyne Hospitals Foundation Trust | Department of Chemistry,