• Disease
  • Mycoplasma
  • Mycoplasma Pneumoniae
  • Ken B Waites

    Prominent publications by Ken B Waites

    KOL Index score: 15491

    PURPOSE: To compare the clinical utility of bone marrow biopsy and culture specimens with blood cultures for mycobacterial and fungal infections among human immunodeficiency virus (HIV)-infected patients.

    PATIENTS AND METHODS: All bone marrow biopsies obtained from HIV-infected patients at the University of Alabama at Birmingham (UAB) Medical Center during 1993 to 1995 were blindly reviewed in a standardized format. Bone marrow culture results and blood culture results obtained within 6 ...

    Also Ranks for: Bone Marrow |  blood culture |  fungal infections |  infected patients |  cd4 count
    KOL Index score: 14799

    The MB/BacT system (MB/BacT) with a revised antibiotic supplement kit was compared with the BACTEC 460 system (BACTEC 460) in a test of 488 specimens submitted for mycobacterial culture from 302 patients. Twenty-four Mycobacterium tuberculosis isolates were detected by the BACTEC 460 versus 23 isolates by the MB/BacT. Mean time until detection of M. tuberculosis isolates identified by both systems was 11.9 days for the BACTEC 460 versus 13.7 days for the MB/BacT (P = 0.046). M. avium ...

    Also Ranks for: Bactec 460 |  mb bact |  clinical specimens |  time detection |  avium complex
    KOL Index score: 14159

    The in vitro activities of two investigational quinolones, sparfloxacin (previously designated AT 4140) and PD 127391, were determined for 30 strains each of Mycoplasma pneumoniae, Mycoplasma hominis, and Ureaplasma urealyticum and compared with those of ciprofloxacin, tetracycline, clindamycin, and erythromycin. Erythromycin was the most active compound against M. pneumoniae (maximum MIC, less than 0.008 microgram/ml). PD 127391 (MICs, less than 0.008 to 0.031 microgram/ml), ...

    Also Ranks for: Mycoplasma Pneumoniae |  ureaplasma urealyticum |  vitro susceptibilities |  tetracycline mics |  025 microgram
    KOL Index score: 12611

    Vancomycin MIC creep has been reported by some institutions but not confirmed in large surveillance studies. We evaluated the possible occurrence of MIC creep when testing vancomycin and daptomycin against methicillin (oxacillin)-resistant Staphylococcus aureus (MRSA) by using precise incremental reference MIC methods. Nine hospitals (one in each U.S. census region) randomly selected bloodstream MRSA strains (target, 40/year) from 2002 to 2006. MICs were determined by the reference broth ...

    Also Ranks for: Mic Creep |  aureus isolates |  resistant staphylococcus |  vancomycin daptomycin |  electrophoresis gel
    KOL Index score: 12599

    To elucidate the pathogenesis of Helicobacter pylori-associated gastritis, we studied immune responses of C57BL/6J wild-type (WT), SCID, and gene deficient (IFN-gamma-/- and IL-4-/-) mice following infection with a pathogenic isolate of H. pylori (SPM326). During early infection in WT mice, mononuclear and polymorphonuclear cells accumulated in the gastric lamina propria, and the numbers of cells in the inflamed mucosa expressing IFN-gamma, but not IL-4, mRNA rose significantly (p < ...

    Also Ranks for: Gastric Inflammation |  knockout mice |  helicobacter pylori |  ifn gamma |  th1 cells
    KOL Index score: 12225

    We studied 198 macrolide-resistant S. pneumoniae isolates obtained from adults and children to evaluate whether 2-microgram clindamycin disks can distinguish between isolates manifesting ermB- versus mefE-mediated resistance to clarithromycin and to determine the relative frequency with which each resistance mechanism occurred in these populations. The mefE gene was predominant among 109 isolates from children, occurring in 73.4% versus 50.6% of 89 isolates from adults. Three isolates ...

    Also Ranks for: Macrolide Resistance |  pneumoniae isolates |  clindamycin disks |  respiratory tract |  mefe gene
    KOL Index score: 12127

    BACKGROUND: Epidemiologic data from Asia have documented the rapid and extensive emergence of macrolide resistance in Mycoplasma pneumoniae. This drug resistance has also been documented in Europe and recently in the United States, but there is very little information currently available on its prevalence. A rapid technique to identify macrolide-resistant M. pneumoniae is needed to guide management of patients with community-acquired respiratory infections.

    METHODS: Culture and Minimum ...

    Also Ranks for: Macrolide Resistance |  mycoplasma pneumoniae |  clinical specimens |  23s rrna gene |  pneumonia ribosomal
    KOL Index score: 12080

    The in vitro susceptibilities to garenoxacin (BMS-284756), an investigational des-fluoroquinolone, and eight other agents were determined for 63 Mycoplasma pneumoniae, 45 Mycoplasma hominis, 15 Mycoplasma fermentans, and 68 Ureaplasma sp. isolates. Garenoxacin was the most active quinolone, inhibiting all isolates at

    Also Ranks for: Bactericidal Activities |  vitro susceptibilities |  human mycoplasmas |  antimicrobial agents |  levofloxacin ciprofloxacin
    KOL Index score: 11492

    The in vitro susceptibilities of 69 nosocomial Acinetobacter isolates were determined by the broth microdilution method. Fourteen (20%) isolates were resistant to at least two aminoglycosides and two extended-spectrum penicillins. Nine antimicrobial combinations were then tested for synergy against these 14 isolates by checkerboard titration: imipenem with ciprofloxacin, amikacin, and tobramycin and ampicillin-sulbactam, piperacillin-tazobactam, and ticarcillin-clavulanate with amikacin ...

    Also Ranks for: Acinetobacter Baumannii |  synergistic activities |  nosocomial isolates |  antimicrobial combinations |  ampicillin sulbactam
    KOL Index score: 11427

    Studies were conducted on a method of direct inoculation of MicroScan dried overnight and of rapid panels with positive aerobic blood cultures obtained from the BacT/Alert to determine antimicrobial susceptibilities. Inocula were limited to specimens that appeared unimicrobic on Gram stain. Results were compared to those obtained from panels inoculated following subculture. For 133 gram-negative bacilli, there were 94.7 and 93.5% categorical agreements between direct and standard methods ...

    Also Ranks for: Rapid Panels |  direct susceptibility |  major error |  blood cultures |  gram positive
    KOL Index score: 11301

    The PROTEKT surveillance study commenced in 1999 to examine the antimicrobial susceptibility of community-acquired respiratory pathogens. We report here the results from 2371 isolates collected during 2000 by North American centers (Canada, n = 7; USA, n = 8). Overall, 21.3% of pneumococci (n = 687) were penicillin G-resistant (Canada, 10.3%; USA, 32.6%). Corresponding rates of erythromycin resistance were 16.3% and 31.5%. Telithromycin inhibited all penicillin- and ...

    Also Ranks for: Antimicrobial Susceptibility |  acquired respiratory |  tract pathogens |  united states |  erythromycin resistance
    KOL Index score: 11068

    The study objective was to determine whether Ureaplasma respiratory tract colonization of preterm infants <33 wk gestation is associated with an increased risk for necrotizing enterocolitis (NEC). One or more tracheal or nasopharyngeal aspirates for Ureaplasma culture and PCR were obtained during the first week of life from 368 infants <33 wk gestation enrolled from 1999 to 2003 or from 2007 to 2009. NEC Bell stage ≥ 2 was confirmed by radiological criteria, and pathology, if available. ...

    Also Ranks for: Preterm Infants |  ureaplasma colonization |  necrotizing enterocolitis |  newborn infant |  histological chorioamnionitis
    KOL Index score: 10714

    OBJECTIVE: To estimate the frequency of genital tract colonization by methicillin-resistant Staphylococcus aureus (MRSA) among pregnant women and evaluate the association of such colonization with infant outcome.

    METHODS: Between July 2003 and July 2006, anovaginal screening cultures for group B Streptococcus (GBS) were prospectively obtained in the third trimester (35 to less than 37 weeks of gestation) and were also processed for identification of Staphylococcus aureus including ...

    Also Ranks for: Staphylococcus Aureus |  genital tract |  pregnant women |  mrsa colonization |  infectious pregnancy
    KOL Index score: 10636

    Ureaplasma spp. respiratory tract colonization is a significant risk factor for bronchopulmonary dysplasia (BPD), a chronic lung disorder in preterm infants. As an initial step preparatory to future clinical trials to evaluate the clinical efficacy of azithromycin to prevent BPD, the authors characterized the pharmacokinetics, safety, and biological effects of a single intravenous dose of azithromycin (10 mg/kg) in preterm neonates (n = 12) 24 to 28 weeks gestation at risk for Ureaplasma ...

    Also Ranks for: Preterm Infants |  premature infant |  bronchopulmonary dysplasia bpd |  safety azithromycin |  ureaplasma spp


    Ken B Waites: Influence Statistics

    Sample of concepts for which Ken B Waites is among the top experts in the world.
    Concept World rank
    levofloxacin 994 #1
    135–147 dga #1
    mycoplasmology international #1
    azithromycin bronchopulmonary #1
    students mycoplasma #1
    diseases infant pcr #1
    growth fastidious organism #1
    eradicating intra #1
    streptococcus pneumoniae organisms #1
    12 mycoplasma fermentans #1
    uropathogens bacteriuria #1
    bact bottles #1
    tests mycoplasma #1
    vntrs levels #1
    lengths gyra #1
    states ureaplasma #1
    mics dilutions #1
    concomitantly drawn samples #1
    macrolideresistant pneumoniae children #1
    20 ureaplasma parvum #1
    4dilution #1
    vntrs mycoplasma #1
    neonates consideration #1
    arylfluoroquinolones vitro activities #1
    designation ureaplasma biovars #1
    human mycoplasma infections #1
    clindamycin sparfloxacin #1
    mics 05 microgram #1
    antiurease antibody titres #1
    additional bloodstream isolates #1
    ureaplasmainfected spermatozoa #1
    europe mrmp #1
    prevalence mlsbi #1
    tests fluoroquinolone mics #1
    inadequate co2 production #1
    elitech platform #1
    prokaryotes focus #1
    growth inhibition epiimmunofluorescence #1
    33 ureaplasma #1
    neonatal reflex behaviors #1
    isolation ofacholeplasma oculi #1
    13 mycoplasma hominis #1
    bactericidal activities pneumoniae #1
    inaccuracies standardized methods #1
    mics≥ 8 μg #1
    hominis omadacycline #1
    05 microgram tetracycline #1
    quantitate frequency #1
    bact alert instrument #1
    ureaplasmapositive 146 #1

    Key People For Mycoplasma Pneumoniae

    Top KOLs in the world
    Ken B Waites
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    Deborah F Talkington
    mycoplasma pneumoniae united states typhoid fever
    Wallace A Clyde
    mycoplasma pneumoniae attachment protein monoclonal antibodies
    Joel Barry Baseman
    mycoplasma pneumoniae cards toxin treponema pallidum
    Enno Jacobs
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    mycoplasma pneumoniae extrapulmonary manifestations cerebrospinal fluid

    Ken B Waites:Expert Impact

    Concepts for whichKen B Waiteshas direct influence:Mycoplasma pneumoniae,  United states,  Ureaplasma urealyticum,  Mycoplasma hominis,  Spinal cord injury,  Preterm infants,  Human mycoplasmas,  Macrolide resistance.

    Ken B Waites:KOL impact

    Concepts related to the work of other authors for whichfor which Ken B Waites has influence:Mycoplasma pneumoniae,  Ureaplasma urealyticum,  Helicobacter pylori,  Staphylococcus aureus,  Spinal cord injury,  Macrolide resistance,  Amniotic fluid.



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    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA | Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA. | Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 3529