• KOLs
  • Urea Cycle
  • Cytonet Gmbh & Co. Kg

Direct Impact

Concepts for which Cytonet GmbH & Co KG has direct influence:

urea cycle
ucd mutations
isotope ratio
genetically disposed
liver cells
rare inherited

Prominent publications by Cytonet GmbH & Co. KG

KOL-Index: 2 Urea cycle disorders are rare inherited diseases that generally have a poor outcome. In this study, neonates and infants with UCD will be included within the first 3 months of life and will be treated by repetitive application of human liver cells to reduce the risk of neurological deterioration while awaiting OLT. Detailed Description Urea cycle disorders are rare inherited diseases that ...
Known for
Neurological Deterioration | Repetitive Application
KOL-Index: 2 This diagnostic study will be performed to investigate the performance of the urea cycle in healthy subjects, asymptomatic carriers of Urea Cycle Disorders (UCD) mutations and subjects with genetically proven urea cycle disorders. The ureagenesis rate will be measured by 13C incorporation assay, a method for in vivo measurement of urea cycle performance with stable isotopes. Detailed ...
Known for
Incorporation Method | Sodium 13c-Acetate | Diagnostic Performed | Disorders Ureagenesis
KOL-Index: 2 In this short-term study a method for the evaluation of the metabolic competency of the urea cycle in vivo will be assessed. In order to monitor the efficacy of new treatment options for patients with urea cycle disorders and to monitor the severity of the disease, a reliable and safe quantitative method for the measurement of the urea cycle flux is required.Urea synthesis will be evaluated ...
Known for
Subsequent Incorporation | Administering Sodium | Urea Synthesis
KOL-Index: 2 Treatment with liver cell infusion for children with urea cycle disorders (UCD). Detailed Description Urea cycle disorders are rare inherited diseases that generally have a poor outcome, especially with onset of the disease in the neonatal period. UCDs are caused by a deficiency of one of six enzymes responsible for removing ammonia from the bloodstream. Instead of being converted into urea ...

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