• Disease
  • Democratic
  • Democratic Republic
  • Mary G Reynolds

    Prominent publications by Mary G Reynolds

    KOL Index score: 12961

    BACKGROUND: In September, 2017, human monkeypox re-emerged in Nigeria, 39 years after the last reported case. We aimed to describe the clinical and epidemiological features of the 2017-18 human monkeypox outbreak in Nigeria.

    METHODS: We reviewed the epidemiological and clinical characteristics of cases of human monkeypox that occurred between Sept 22, 2017, and Sept 16, 2018. Data were collected with a standardised case investigation form, with a case definition of human monkeypox that ...

    Also Ranks for: Human Monkeypox |  virus nigeria |  west african |  reported case |  genome sequencing
    KOL Index score: 12887

    On June 25, 2015, the Advisory Committee on Immunization Practices (ACIP) recommended routine vaccination with live smallpox (vaccinia) vaccine (ACAM2000) for laboratory personnel who directly handle 1) cultures or 2) animals contaminated or infected with replication-competent vaccinia virus, recombinant vaccinia viruses derived from replication-competent vaccinia strains (i.e., those that are capable of causing clinical infection and producing infectious virus in humans), or other ...

    Also Ranks for: Occupational Exposure |  vaccinia virus |  smallpox vaccine |  advisory committee |  immunization practices
    KOL Index score: 8330

    Monkeypox virus, a zoonotic member of the genus Orthopoxviridae, can cause a severe, smallpox-like illness in humans. Monkeypox virus is thought to be endemic to forested areas of western and Central Africa. Considerably more is known about human monkeypox disease occurrence than about natural sylvatic cycles of this virus in non-human animal hosts. We use human monkeypox case data from Africa for 1970-2003 in an ecological niche modeling framework to construct predictive models of the ...

    Also Ranks for: Human Monkeypox |  geographic distribution |  ecological niche |  central africa |  forested areas
    KOL Index score: 8189

    BACKGROUND: Cat-scratch disease (CSD), caused by infection with Bartonella henselae, affects both children and adults but is principally a pediatric disease. Typical CSD is generally benign and self-limited and is characterized by regional lymphadenopathy with fever. Infections can, however, be accompanied by focal or diffuse inflammatory responses (atypical CSD) involving neurologic, organ (liver/spleen), lymphatic or skeletal systems.

    METHODS: Pediatric hospitalizations with CSD listed ...

    Also Ranks for: United States |  scratch disease |  bartonella henselae |  national estimates |  neurologic complications
    KOL Index score: 8005

    We have exploited the experimental accessibility of the protozoan parasite Toxoplasma gondii and its similarity to Plasmodium falciparum to investigate the influence of specific dihydrofolate reductase polymorphisms known from field isolates of drug-resistant malaria. By engineering appropriate recombinant shuttle vectors, it is feasible to examine mutations by transient or stable transformation of T. gondii parasites, in bacterial and yeast complementation assays, and through ...

    Also Ranks for: Plasmodium Falciparum |  toxoplasma gondii |  parasite resistance |  biochemical analysis |  folic acid
    KOL Index score: 7709

    A monkeypox outbreak occurred in the United States in 2003. Patient's sera were sent to the Centers for Disease Control and Prevention as a part of outbreak response measures. Clinical and epidemiologic information was abstracted from the case investigation forms. Serum samples from patients were tested by using an immunoglobulin M (IgM)-capture and an IgG enzyme-linked immunosorbent assay ELISA against Orthopoxvirus antigen. The detection of antiviral IgG and IgM antibodies and the ...

    Also Ranks for: United States |  monkeypox infection |  linked immunosorbent |  igm antibodies |  humoral immunity
    KOL Index score: 7356

    The recent apparent increase in human monkeypox cases across a wide geographic area, the potential for further spread, and the lack of reliable surveillance have raised the level of concern for this emerging zoonosis. In November 2017, the World Health Organization (WHO), in collaboration with CDC, hosted an informal consultation on monkeypox with researchers, global health partners, ministries of health, and orthopoxvirus experts to review and discuss human monkeypox in African ...

    Also Ranks for: Central Africa |  cases monkeypox |  health organization |  republic congo |  control measures
    KOL Index score: 7296

    Like Plasmodium, the protozoan parasite Toxoplasma gondii is a member of the phylum Apicomplexa, and an obligate intracellular pathogen. Unlike Plasmodium, however, Toxoplasma is highly amenable to experimental manipulation in the laboratory. The development of molecular transformation protocols for T. gondii has provided both scientific precedent and practical selectable markers for Plasmodium. Beyond the feasibility of molecular biological experimentation now possible in both systems, ...

    Also Ranks for: Toxoplasma Model |  protozoan parasite |  phylum apicomplexa |  cell biological analysis |  molecular genetic
    KOL Index score: 7169

    Human monkeypox has never been reported in Ghana, but rodents captured in forested areas of southern Ghana were the source of the monkeypox virus introduced into the United States in 2003. Subsequent to the outbreak in the United States, 204 animals were collected from two commercial trapping sites in Ghana. Animal tissues were examined for the presence of orthopoxvirus (OPXV) DNA using a real-time polymerase chain reaction, and sera were assayed for antibodies against OPXV. Animals from ...

    Also Ranks for: West Africa |  united states |  opxv dna |  human monkeypox |  animals antibodies
    KOL Index score: 7076

    BACKGROUND: Monkeypox (MPX) is an endemic disease of public health importance in the Democratic Republic of the Congo (DRC). In 2010, the DRC Ministry of Health joined with external partners to improve MPX surveillance in the Tshuapa Health District of DRC. A pivotal component of the program is training of health zone personnel in surveillance methods and patient care. In this report we evaluate outcomes of the training program.

    METHODS: Health care worker knowledge of key concepts in ...

    Also Ranks for: Democratic Republic |  public health |  drc ministry |  monkeypox mpx |  endemic diseases
    KOL Index score: 7071

    An increased incidence of monkeypox (MPX) infections in the Democratic Republic of the Congo was noted by the regional surveillance system in October 2013. Little information exists regarding how MPX is introduced into the community and the factors associated with transmission within the household. Sixty-eight wild animals were collected and tested for Orthopoxvirus. Two of three rope squirrels (Funisciurus sp.) were positive for antibodies to Orthopoxviruses; however, no increased risk ...

    Also Ranks for: Democratic Republic |  monkeypox virus |  rope squirrels |  community transmission |  increased incidence
    KOL Index score: 6629

    BACKGROUND: The epidemiology of Molluscum contagiosum (MC) in the United States is largely unknown, despite the fact that the virus is directly communicable and large outbreaks occur. This study provides population-based estimates to describe the epidemiology of MC in the United States among American Indian and Alaska Native (AI/AN) persons. This population was selected because of the comprehensiveness and quality of available data describing utilization of out-patient ...

    Also Ranks for: Molluscum Contagiosum |  epidemiology mc |  alaska native |  incidence indians |  rate general
    KOL Index score: 6607

    Following the U.S. monkeypox outbreak of 2003, blood specimens and clinical and epidemiologic data were collected from cases, defined by standard definition, and household contacts of cases to evaluate the role of preexisting (smallpox vaccine-derived) and acquired immunity in susceptibility to monkeypox disease and clinical outcomes. Orthopoxvirus-specific immunoglobulin G (IgG), IgM, CD4, CD8, and B-cell responses were measured at approximately 7 to 14 weeks and 1 year postexposure. ...

    Also Ranks for: Smallpox Vaccination |  complete protection |  cd4 cd8 |  united states |  immune responses


    Mary G Reynolds: Influence Statistics

    Sample of concepts for which Mary G Reynolds is among the top experts in the world.
    Concept World rank
    orthopoxviruses geographic biases #1
    identified cundinamarca #1
    orthopoxviruses disease control #1
    hypothesis aka people #1
    presumptive hostrange genes #1
    highly specialized singlehost #1
    colombia cundinamarca department #1
    comparison monkeypox outbreak #1
    farmworkers opxv #1
    identified farmworkers #1
    aka bantu groups #1
    relaxed selection contrast #1
    unvaccinated partner #1
    opxv smallpox #1
    vigiv transmission #1
    acam2000 risk #1
    early release seroprevalence #1
    partners smallpox #1
    orthopoxvirus sexual #1
    acam2000 laboratory #1
    monkeypox health approach #1
    orthopoxviruses advisory #1
    acam2000 laboratory personnel #1
    unvaccinated partner county #1
    aka people #1
    animal urine feces #1
    cundinamarca department vacv #1
    patient unvaccinated partner #1
    vaccinia vaccine acam2000 #1
    patient sexual contacts #1
    enigmatic usual suspects #1
    contact monkeypox #1
    usual suspects orthopoxviruses #1
    vaccinia patient #1
    orthopoxviruses 1 #1
    prevention vaccinia virus #1
    farmworkers opxv antibodies #1
    county smallpox vaccine #1
    health approach nigeria #1
    acam2000 recommendation #1
    vaccinee patient #1
    orthopoxviruses acam2000 #1
    humans recommendation category #1
    orthopoxvirus practice #1
    aka ethnicity #1
    orthopoxvirus risk #1
    vaccinee san #1
    bantu suspected #1
    forest ≥ #1
    orthopoxvirus host range #1

    Key People For Democratic Republic

    Top KOLs in the world
    Jean Jacques Muyembe‐Tamfum
    democratic republic ebola virus congo drc
    JeanJacques Tamfum Muyembe
    democratic republic central africa congo drc
    Antoinette Kitoto Tshefu
    democratic republic pregnant women global network
    Steven Richard Meshnick
    democratic republic plasmodium falciparum pregnant women
    Pascal Tshindele Lutumba
    democratic republic human african trypanosomiasis sleeping sickness
    Pierre B H Formenty
    ebola virus democratic republic sierra leone

    Mary G Reynolds:Expert Impact

    Concepts for whichMary G Reynoldshas direct influence:Democratic republic,  Human monkeypox,  Vaccinia virus,  Democratic republic congo,  Congo basin,  Central africa,  Monkeypox virus,  Molluscum contagiosum.

    Mary G Reynolds:KOL impact

    Concepts related to the work of other authors for whichfor which Mary G Reynolds has influence:Monkeypox virus,  Democratic republic,  Smallpox vaccine,  Molluscum contagiosum,  Infectious diseases,  Public health,  Toxoplasma gondii.



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    Poxvirus and Rabies Branch, Centers for Disease Control and Prevention, NE, Atlanta, GA | Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, Atlanta, GA 30333, USA | Division of High Consequence Pathogens and Pathology, Centers for Dise