Lazar John GREENFIELDShow email address
Department of Neurology, University of Connecticut Health Center, Farmington, CT 06030, USA. | Department of Neurology, University of Arkansas for Medical Sciences, Little ...
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Lazar John GREENFIELD:Expert Impact
Concepts for whichLazar John GREENFIELDhas direct influence:Vena cava,Pulmonary embolism,Venous thrombosis,Greenfield filter,Preoptic area,Total cost,Senior surgeons,Heart rate.
Lazar John GREENFIELD:KOL impact
Concepts related to the work of other authors for whichfor which Lazar John GREENFIELD has influence:Pulmonary embolism,Vena cava,Venous thrombosis,Septic shock,Trauma patients,Aortic aneurysm,Bariatric surgery.
KOL Resume for Lazar John GREENFIELD
Department of Neurology, University of Connecticut Health Center, Farmington, CT 06030, USA.
Department of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA; Department of Neurology, University of Connecticut Health Center, Farmington, CT 06030, USA.
Department of Neurology, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
From the Department of Neurology, University of Arkansas for Medical Sciences, Arkansas, United States of America
Department of Neurology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America
Dept. of Neurology, University of Arkansas for Medical Sciences, 4301W. Markham St., Slot 500, Little Rock, AR 72205, United States
Department of Physiology & Pharmacology, University of Toledo College of Medicine, Toledo, OH, USA
Department of Surgery, Vascular Surgery Section, University of Michigan School of Medicine, Ann Arbor, Mich
Department of Physiology and Pharmacology, University of Toledo College of Medicine, Health Science Campus, Toledo, OH 43614-2598, USA
Ann Arbor, MI
Department of Surgery, University of Michigan School of Medicine, Ann Arbor, Mich
Department of Surgery, University of Michigan, Ann Arbor, MI, USA.
From the University of Michigan, MA.
Cellular and Molecular Neurobiology Program and Departments of Neurology and Pharmacology, Medical College of Ohio, Toledo, OH 43614, USA
From the Section of Vascular Surgery, Department of Surgery, University of Michigan, School of Medicine, Ann Arbor, Michigan.
Department of Surgery, University of Michigan Medical Center, Ann Arbor, Mich, USA
Ann Arbor, Mich
From the Section of Vascular Surgery, Department of Surgery, University of Michigan Medical Center, Ann Arbor, Michigan, and Division of Vascular Surgery, Wayne State University School of Medicine, Detroit, Michigan
Departments of Neurology and Pharmacology, Medical College of Ohio, Toledo, OH, USA
Division of Trauma Burn and Emergency Surgery (Taheri, Dechert, Greenfield), University of Michigan Health System, Ann Arbor, MI, USA
From the Department of Surgery,a and Department of Physical Medicine and Rehabilitation,b University of Michigan Hospitals
University of Michigan Health System, Ann Arbor, MI.
From the *Division of Trauma, Burn, and Emergency Surgery, Department of Surgery, University of Michigan Health System; the †Section of Business Economics, University of Michigan School of Business Administration; and the ‡Department of Finance, University of Michigan Medical Center, Ann Arbor, Michigan
Ann Arbor, Mich, and Portland, Ore
Division of Trauma Burn and Emergency Surgery, Department of Pulmonary Medicine (Taheri, Greenfield), University of Michigan Hospital, Ann Arbor, MI, USA
Departments of (Cornish, O'Reilly) Anesthesiology and (Greenfield, Allan) Surgery, University of Michigan Medical Center, Ann Arbor, Michigan. Accepted for publication January 26, 1999. Address correspondence and reprint requests to Philip B. Cornish, FANZA, Department of Anaesthesia, Wellington Hospital, Riddiford St., Wellington, New Zealand.
Professor and Chairman, Department of Surgery, The University of Michigan, Ann Arbor, Michigan
Department of Surgery, University of Michigan, Ann Arbor, Michigan, USA
Section of Vascular Surgery, Department of Surgery, University of Michigan Medical Center,Ann Arbor, MI,USA
From the Boston Scientific Corporation, Natick, Mass., USA
Ann Arbor and Kalamazoo, Mich
Cytel Corporation, San Diego, California, 92121
Section of Vascular Surgery, Department of Surgery, University of Michigan Medical Center, Ann Arbor, MI. USA
Pharmacia & Upjohn, Kalamazoo, Michigan, 48176
Department of Surgery The University of Michigan Ann Arbor, Michigan
From the Section of Vascular Surgery and Jobst Vascular Research Laboratory, Department of Surgery (T.W.W., A.M.K., S.K.W., R.S., L.J.G.); the Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine (R.M.S., C.A.W., M.D.B); and the Department of Pathology (S.L.K.), University of Michigan Medical Center, Ann Arbor.
Department of Surgery, University of Michigan Medical Center, Michigan, USA
San Francisco, Calif., and Ann Arbor, Mich
|normothermic conditions depression||#1|
|patient recurrent embolism||#1|
|patients productive lives||#1|
|level 40 gm||#1|
|edema precapillary segment||#1|
|initial pathologic development||#1|
|2109 consecutive patients||#1|
|normative agedmatched controls||#1|
|protection recurrent embolism||#1|
|complex interdependency factors||#1|
|thromboembolism venae cavae||#1|
|ultrasound scans 30||#1|
|resolution thrombus weight||#1|
|humans operative workforce||#1|
|antibiotic therapy greenfield||#1|
|antiplatelet therapy bci||#1|
|survival 22 patients||#1|
|birds nest device||#1|
|diazepam ca2 currents||#1|
|major massive patients||#1|
|day hospital stay||#1|
|tests investigational device||#1|
|michigan filter registry||#1|
|sleep capneography cure||#1|
|pyramidal cells pvbcs||#1|
|senior surgeons study||#1|
|development transvenous methods||#1|
|baseline surgical training||#1|
|status surgical practice||#1|
|optional filters function||#1|
|twentyyear clinical experience||#1|
|thromboembolism rapt scale||#1|
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Prominent publications by Lazar John GREENFIELD
Length of stay has minimal impact on the cost of hospital admission11No competing interests declared.
[ PUBLICATION ]
BACKGROUND: Hospital cost containment, cost reduction, and alternative care delivery systems continue to preoccupy health care providers, payers, employers, and policy makers throughout the United States. The universal metric for gauging the success of these efforts is hospital length of stay (LOS). Reducing the LOS purportedly yields large cost savings. The purpose of this study is to assess precisely how much hospitals save by shortening LOS.
STUDY DESIGN: We reviewed the ...
|Known for Patients Day | Hospital Length | Total Cost | Trauma Center | Competing Interests|
Relationship of the proinflammatory cytokines to myocardial ischemia and dysfunction after uncomplicated coronary revascularization
[ PUBLICATION ]
The proinflammatory cytokines have been implicated in mediating myocardial dysfunction associated with myocardial infarction, severe congestive heart failure, and sepsis. We tested the hypothesis that cytokine levels are elevated after uncomplicated coronary artery bypass grafting and associated with episodes of postoperative myocardial ischemia and dysfunction. Coronary artery bypass grafting was performed under general anesthesia with moderate systemic hypothermia and cold-blood ...
|Known for Proinflammatory Cytokines | Myocardial Ischemia | Cardiopulmonary Bypass | Ventricular Dysfunction | Coronary Revascularization|
Benzodiazepine Withdrawal-Induced Glutamatergic Plasticity Involves Up-Regulation of GluR1-Containing α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid Receptors in Hippocampal CA1 Neurons
[ PUBLICATION ]
Modification of glutamatergic synaptic function, a mechanism central to neuronal plasticity, may also mediate long-term drug effects, including dependence and addiction. Benzodiazepine withdrawal results in increased glutamatergic strength, but whether alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors (AMPARs) are functionally and structurally remodeled during benzodiazepine withdrawal is uncertain. Whole-cell recordings of rat hippocampal CA1 neurons, either ...
|Known for Benzodiazepine Withdrawal | Ca1 Neurons | Glutamatergic Plasticity | Acid Receptors | Hippocampal Slices|
Venous Thrombosis–Associated Inflammation and Attenuation With Neutralizing Antibodies to Cytokines and Adhesion Molecules
[ PUBLICATION ]
Thrombosis and inflammation are closely related. However, the response of the vein wall to venous thrombosis has been poorly documented. This study examines the hypothesis that venous thrombosis is associated with an inflammatory response in the vein wall. In a rat model of inferior vena caval thrombosis, vein wall was temporally examined for inflammation by assessment of histopathology, leukocyte morphometrics, and cytokine levels. Animals were killed 1 hour and 1, 3, and 6 days after ...
|Known for Venous Thrombosis | Adhesion Molecules | Vein Wall | Thrombus Induction | Inflammatory Response|
[ PUBLICATION ]
OBJECTIVES: Although recent studies suggest that physician age is inversely related to clinical performance in primary care, relationships between surgeon age and patient outcomes have not been examined systematically.
METHODS: Using national Medicare files, we examined operative mortality in approximately 461,000 patients undergoing 1 of 8 procedures between 1998 and 1999. We used multiple logistic regression to assess relationships between surgeon age (< or =40 years, 41-50 years, ...
|Known for Surgeon Age | Operative Mortality | United States | Patient Characteristics | 40 Years|
[ PUBLICATION ]
PURPOSE: The purpose of this study was to compare the efficacy of P-selectin inhibition with standard anticoagulant and thrombolytic therapy in a rodent model of established deep vein thrombosis (DVT).
METHODS: Rats underwent temporary inferior vena cava (IVC) ligation for 2 days to create a stasis-induced thrombosis. On day 2, the animals had the IVC ligature removed and received either recombinant P-selectin glycoprotein ligand-Ig (rPSGL-Ig; 4 mg/kg) intravenously, low-molecular weight ...
|Known for Vein Wall | Thrombus Resolution | Rat Model | Day Controls | Vena Cava|
[ PUBLICATION ]
Human NT2 teratocarcinoma cells differentiate into neuron-like NT2-N cells when treated with retinoic acid. GABA evoked concentration-dependent whole-cell currents in NT2-N cells with an EC50 of 21.8 microM and a Hill slope of 1.2. GABAA receptor (GABAR) currents reversed at ECl- and did not display voltage-dependent rectification. GABAR single channels opened in bursts to a 23 pS main conductance level and a 19 pS subconductance level, with infrequent openings to a 27 pS conductance ...
|Known for Gabaa Receptor | Gabar Currents | Mrna Expression | Nt2n Cells | Conductance Level|
Clinical characteristics and surgical management of vascular complications in patients undergoing cardiac catheterization: Interventional versus diagnostic procedures
[ PUBLICATION ]
The purpose of this report is to define the clinical characteristics and outcome of surgical management of vascular complications after interventional cardiac catheterization and to contrast them to those after diagnostic cardiac catheterization. From October 1985 to December 1989, 101 patients were treated for 106 vascular complications after 1866 interventional and 5046 diagnostic cardiac catheterizations at the University of Michigan Medical Center. Interventional catheterizations ...
|Known for Vascular Complications | Cardiac Catheterization | Surgical Management | Clinical Characteristics | Coronary Angioplasty|
Initial efforts to modify the stainless steel Greenfield filter for percutaneous insertion led to development of a titanium Greenfield filter, which could be inserted by use of a 12F carrier. This device functioned well as a filter but had an unacceptable 30% rate of migration, tilting, and penetration. Therefore a titanium Greenfield filter with modified hooks was developed and has been tested in 186 patients at 10 institutions. Successful placement occurred in 181 (97%); placement of ...
|Known for Titanium Greenfield Filter | Multicenter Study | Modified Hook | Vena Cava | Percutaneous Insertion|
[ PUBLICATION ]
OBJECTIVE: In the absence of ischemic events, arterial pathology at the thoracic outlet (TO) is rarely identified because findings of chronic arterial pathology may be masked by symptoms of neurogenic compression. This study describes the clinical presentations and significance of arterial compression at the TO.
METHODS: This was a retrospective analysis of the clinical records and imaging studies of 41 patients with objective findings of arterial compression at the TO. Sixteen were ...
|Known for Thoracic Outlet | Arterial Compression | Patients Symptoms | Bone Anomaly | Subclavian Artery|
Growing evidence supports the concept that oxygen free radicals are an important cause of myocardial ischemic and reperfusion injury. This study was designed to determine if toxic oxygen metabolites may exacerbate ischemic injury upon reoxygenation. Left ventricular function was studied in a group of seven dogs receiving intermittent, 4 degrees C, hyperosmolar, hyperkalemic (KCI 25 mEq/L) saline cardioplegic solution. This group was compared to a group (n = 7) receiving a hyperkalemic ...
|Known for Free Radical | Reperfusion Injury | Allopurinol Pretreatment | Induced Myocardial | Cardioplegic Solution|
OBJECTIVE: To determine whether high-volume hospitals (HVHs) have lower in-hospital death rates after abdominal aortic aneurysm (AAA) repair compared with low-volume hospitals (LVHs).
SUMMARY BACKGROUND DATA: Select statewide studies have shown that HVHs have superior outcomes compared with LVHs for AAA repair, but they may not be representative of the true volume-outcome relationship for the entire United States.
METHODS: Patients undergoing repair of intact or ruptured AAAs in the ...
|Known for Aortic Aneurysm | United States | Aaa Repair | Hospital Death | Intact Ruptured|
[ PUBLICATION ]
OBJECTIVE: This study was performed to determine the effectiveness of recombinant P-selectin glycoprotein ligand Ig (rPSGL-Ig) pretreatment to decrease thrombosis and inflammation in experimental venous thrombosis. rPSGL-Ig, a unique mucin-like glycoprotein, has a high affinity for P-selectin.
METHODS: Twelve juvenile baboons underwent inferior vena cava (IVC) thrombosis with temporary 6-hour IVC balloon occlusion. Before balloon placement, the animals received rPSGL-Ig (4 mg/kg; n = 8) ...
|Known for Venous Thrombosis | Anticoagulation Therapy | Thrombus Resolution | Control Animals | Vein Wall|
[ PUBLICATION ]
BACKGROUND: Previous studies have demonstrated inadequate reimbursement for severely injured patients with a resultant negative economic impact for the trauma service and hospital. The purpose of this study was to assess the total cost of care for all injured patients discharged from the trauma service in fiscal year 1997, and to determine the proportion of costs for the most severely injured on total cost. In addition, we assessed the total service costs and the revenue for treatment of ...
|Known for Trauma Service | Profit Center | Total Cost | Injured Patients | Iss Length|