Sexual & Reproductive Medicine Program, Urology Service, Memorial Sloan Kettering Cancer Center, New York, Ny, Usa.

Direct Impact

Concepts for which PATRICIA GUHRING has direct influence:

venous leak
sildenafil citrate
erectile dysfunction
radiation therapy
acrobeads test
prostate cancer
intracavernosal injection

External impact

Concepts related to the work of other authors for which PATRICIA GUHRING has influence:

penile curvature
erectile dysfunction
acrosome-reacted sperm
sildenafil citrate
zona-free hamster egg
phosphodiesterase-5 inhibitors
triple-stain technique

Prominent publications by PATRICIA GUHRING

KOL-Index: 19 OBJECTIVES: To define the likelihood of nitrate users wishing to use sildenafil citrate being permitted by their nitrate-prescribing physicians to cease nitrate use, and to attempt to derive predictors of a "no" response to this request. METHODS: A total of 248 patients with erectile dysfunction were included in this study. All patients using or in possession of nitrates who opted to be ...
Known for
Prescribing Nitrate | Sildenafil Physicians | 248
KOL-Index: 19 PROBLEM: To determine whether the results of the Acrobeads test, which measures the expression of the complement regulator molecule CD46 on the inner acrosomal membrane following the acrosome reaction, accurately identifies semen specimens that will exhibit reduced or failed fertilization following conventional IVF insemination. METHOD: The Acrobeads test was performed on semen specimens ...
Known for
Tritc-Psa-Negative Sperm | Ivf Insemination | Rate Fertilization | 97 Consecutive
KOL-Index: 17 INTRODUCTION: Peyronie's disease (PD) is usually seen in men in their fifth decade of life. AIM: In this study, we investigated the characteristics of the disease in young men. MAIN OUTCOME MEASURES: The demographics, clinical features, and associated comorbidities of the patients with PD were retrospectively reviewed. METHODS: The findings were compared between men with the disease who were ...
Known for
Characteristics Peyronie | Plaque Presentation | Features Groups | Differences Diabetes
KOL-Index: 16 INTRODUCTION: Intracavernosal injection therapy (ICI) is a well-established second-line therapy used in the treatment of erectile dysfunction (ED). Controversy exists as to whether oral phosphodiesterase type 5 inhibitors (PDE5i) or injection therapy lead to higher satisfaction. AIM: This study addressed ICI satisfaction in a modern cohort of patients in the PDE5i era. METHODS: Patients on ...
Known for
Function Iief | 5 Inhibitors | Well-Established Second-Line Therapy | Baseline Scores
KOL-Index: 14 PURPOSE: Erectile dysfunction is a recognized complication of radiation therapy for prostate cancer. Sildenafil citrate is a well-known management strategy for erectile dysfunction that has been found to be efficacious across a wide spectrum of comorbidities, including post-radiation erectile dysfunction. We defined the efficacy of sildenafil citrate in patients with erectile dysfunction ...
Known for
Function Iief | Recognized Complication | Points Crt | Stepwise Decrease
KOL-Index: 13 Study Type--Therapy (outcomes research) Level of Evidence 2b. What's known on the subject? and What does the study add? Intracavernosal injection (ICI) therapy is an important treatment option for erectile dysfunction. However, high discontinuation rates have been reported for ICI therapy, and a risk of priapism has long been a concern. There has never been a large sample study performed ...
Known for
Concern Discontinuation | Year Note | Priapism Rate | Therapy Tertiary
KOL-Index: 10 INTRODUCTION: Sildenafil citrate is an effective and well-tolerated oral erectogenic medication. Through phosphodiesterase type 5 (PDE5) inhibition, it induces relaxation in penile smooth muscle, resulting in erection. Due to its mild affinity for other PDE enzymes, it may cause smooth muscle relaxation in a number of other organs. Recent data suggest an association between erectile ...
Known for
Ipss Points | Forty-Eight | 4-Point Improvement | Muscle Relaxation
KOL-Index: 10 AIM: Peyronie's disease (PD) may be treated in a medical or surgical fashion. Factors involved in the decision of which treatment to choose include duration of disease and magnitude of penile deformity. Curvature can be measured using at-home photography (AHP), vacuum erection device (VED), or intracavernosal injection (ICI). This study was undertaken to determine the concordance between the ...
Known for
Erection | Deformity Ici | Vacuum Device Measurements | Curvatures
KOL-Index: 10 BACKGROUND: Premature ejaculation (PE) is a common sexual dysfunction for which selective serotonin reuptake inhibitors (SSRIs) have been used effectively for treatment. However, compliance with therapy and predictors of long-term SSRI use in the treatment of PE are not well known. AIM: To analyze our experience with drop-out rates with fluoxetine in the primary PE population and to identify ...
Known for
Post-Treatment Ielt | Long-Term Ssri | Drop-Out Rates | Personal Partner
KOL-Index: 9 OBJECTIVE: To define the ability of the International Index of Erectile Function (IIEF) to differentiate between organic and psychogenic erectile dysfunction (ED). PATIENTS AND METHODS: Patients presenting for the evaluation and treatment of ED who had penile duplex Doppler ultrasonography (DUS) completed the IIEF questionnaire. Accepted ranges of the IIEF EF domain were used to grade ...
Known for
Iief Normal | Organic Psychogenic Erectile Dysfunction | Moderate Mild | Hyperlipidaemia

Sexual & Reproductive Medicine Program, Urology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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