• Disease
  • Venous
  • Venous Thromboembolism
  • Ian Andrew Greer

    Prominent publications by Ian Andrew Greer

    KOL Index score: 33172

    OBJECTIVES: To assess the risk of clinical complications associated with thrombophilia in three high-risk patient groups: women using oral oestrogen preparations, women during pregnancy and patients undergoing major orthopaedic surgery. To assess the effectiveness of prophylactic treatments in preventing venous thromboembolism (VTE) and adverse pregnancy outcomes in women with thrombophilia during pregnancy and VTE in patients with thrombophilia, undergoing major orthopaedic surgery. To ...

    Also Ranks for: Thrombophilia Screening |  vte women |  effectiveness analysis |  risk pregnancy
    KOL Index score: 27246

    This article discusses the management of venous thromboembolism (VTE) and thrombophilia, as well as the use of antithrombotic agents, during pregnancy and is part of the American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Grade 1 recommendations are strong and indicate that benefits do, or do not, outweigh risks, burden, and costs. Grade 2 recommendations are weaker and imply that the magnitude of the benefits and risks, burden, and costs are ...

    Also Ranks for: Antithrombotic Therapy |  venous thromboembolism |  ufh pregnancy |  8th edition |  pregnant women
    KOL Index score: 17136

    BACKGROUND: Obesity in pregnancy is increasing and is a risk factor for metabolic pathology such as preeclampsia. In the nonpregnant, obesity is associated with dyslipidemia, vascular dysfunction, and low-grade chronic inflammation.

    AIM: Our aim was to measure microvascular endothelial function in lean and obese pregnant women at intervals throughout their pregnancies and at 4 months after delivery. Plasma markers of endothelial function, inflammation, and placental function and their ...

    Also Ranks for: Endothelial Function |  obesity pregnancy |  obese women |  postpartum period |  bmi 30
    KOL Index score: 16572

    BACKGROUND: The use of anticoagulant therapy during pregnancy is challenging because of the potential for both fetal and maternal complications. This guideline focuses on the management of VTE and thrombophilia as well as the use of antithrombotic agents during pregnancy.

    METHODS: The methods of this guideline follow the Methodology for the Development of Antithrombotic Therapy and Prevention of Thrombosis Guidelines: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American ...

    Also Ranks for: Antithrombotic Therapy |  vte thrombophilia |  grade 1b |  prevention thrombosis |  practice guidelines
    KOL Index score: 16213

    This chapter about the use of antithrombotic agents during pregnancy is part of the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy: Evidence Based Guidelines. Grade 1 recommendations are strong and indicate that the benefits do, or do not, outweigh risks, burden, and costs. Grade 2 suggests that individual patients' values may lead to different choices (for a full understanding of the grading see Guyatt et al, CHEST 2004; 126:179S-187S). Among the key recommendations ...

    Also Ranks for: Lmwh Pregnancy |  thrombolytic therapy |  grade 1c |  antithrombotic agents |  vte women
    KOL Index score: 15128

    In view of the pathological placental features of pre-eclampsia and intrauterine growth restriction (IUGR), and the angiogenic effects of vascular endothelial growth factor (VEGF), the aim of this study was to determine the expression of VEGF in placentae from normal pregnancies and to compare the results with placentae from pregnancies complicated by pre-eclampsia and intrauterine growth restriction (IUGR). ELISA was used to measure circulating VEGF immunoreactivity in umbilical vein ...

    Also Ranks for: Endothelial Growth |  placental hypoxia |  iugr vegf |  normal pregnancies |  stromal cells
    KOL Index score: 15010

    BACKGROUND: Thrombophilias are common disorders that increase the risk of pregnancy-associated venous thromboembolism and pregnancy loss and can also increase the risk of placenta-mediated pregnancy complications (severe pre-eclampsia, small-for-gestational-age infants, and placental abruption). We postulated that antepartum dalteparin would reduce these complications in pregnant women with thrombophilia.

    METHODS: In this open-label randomised trial undertaken in 36 tertiary care centres ...

    Also Ranks for: Pregnant Women |  pregnancy complications |  venous thromboembolism |  thrombophilia risk |  randomised trial
    KOL Index score: 14294

    The abnormal umbilical artery Doppler waveform represented by absent end-diastolic flow velocity (AEDFV) identifies a group of preterm small-for-gestational age fetuses that are at high risk of perinatal death due to chronic fetal hypoxia. The placental ischaemia that results from inadequate trophoblast invasion of spiral arterioles leads to an assumption of placental villous hypoxia, though an alternative explanation is that the placenta fails to adequately transfer oxygen to the fetus ...

    Also Ranks for: Terminal Villi |  umbilical artery |  structural analysis |  intervillous space |  fetal hypoxia
    KOL Index score: 13811

    Platelets and neutrophils are involved in maternal placental vascular damage in pre-eclampsia. Recruitment of these cells is probably mediated by cell adhesion molecules expressed at the uteroplacental bed. It remains controversial as to whether platelets and neutrophils mediate damage to trophoblast or villous vasculature. The purpose of this study was to determine the expression of cell adhesion molecules in placentae from normal pregnancies and pregnancies complicated by pre-eclampsia ...

    Also Ranks for: Cell Adhesion |  growth retardation |  molecule1 eclampsia |  vcam1 selectin |  placentae pregnancies
    KOL Index score: 13787

    OBJECTIVE: Women with polycystic ovary syndrome (PCOS) exhibit an abnormal lipoprotein profile, characterized by raised concentrations of plasma triglyceride, marginally elevated low density lipoprotein (LDL)-cholesterol, and reduced high density lipoprotein (HDL)-cholesterol. However, a normal LDL-cholesterol level may be misleading since LDL exists as subpopulations of particles differing in size and atherogenic potential. Smaller LDL particles are more atherogenic and high ...

    Also Ranks for: Women Pcos |  hl activity |  independent predictors |  cholesterol ldl |  density lipoprotein
    KOL Index score: 13674

    BACKGROUND: There is increasing interest in carrying out pre-induction cervical ripening on an outpatient basis. However, there are concerns about the use of prostaglandins, the agents commonly used in hospital settings for this indication, because prostaglandins induce uterine contractions that may lead to fetal hypoxia. Indeed, in a recent study we demonstrated abnormalities in 9% of fetal heart rate tracings performed following prostaglandin induced cervical ripening at term. In ...

    Also Ranks for: Induction Labour |  cervical ripening |  isosorbide mononitrate |  clinical trial |  imn women
    KOL Index score: 13510

    Women with oligomenorrhea and polycystic ovaries show a high incidence of ovulation failure perhaps linked to insulin resistance and related metabolic features. A number of reports show that the biguanide metformin improves ovarian function. However, in these trials the quality of evidence supporting ovulation is suboptimal, and few studies have been placebo-controlled. The aim of our study was to use a double-blind, placebo-controlled approach with detailed assessment of ovarian ...

    Also Ranks for: Ovarian Function |  metformin placebo |  polycystic ovaries |  controlled trial |  study treatment
    KOL Index score: 13361

    Accumulating evidence suggests that human parturition represents an inflammatory process. Leukocytes are known to infiltrate uterine tissues but the exact timing, nature and quantity of these cells has not been formally characterized. We have previously demonstrated an apparent increase in pro-inflammatory cytokines within tissues of the labouring uterus. The aims of this study were to quantify and compare the leukocyte subpopulations before and during labour in fetal membranes, decidua ...

    Also Ranks for: Mrna Expression |  myometrium cervix |  leukocyte density |  inflammatory process |  onset labour


    Ian Andrew Greer: Influence Statistics

    Sample of concepts for which Ian Andrew Greer is among the top experts in the world.
    Concept World rank
    stewart fm #1
    groups normal pregnancies #1
    pregnancyrelated blood loss #1
    vcam selectin mrna #1
    outcome anxa5 #1
    ccb vivo #1
    mild moderate pih #1
    concentration amniotomy #1
    postnatal dvt #1
    gynaecological episodes #1
    heparin ketorolac #1
    synthesis vasodilator autocoids #1
    new possibilities intervention #1
    tissues iugr #1
    226n3 concentration #1
    growthrestricted cases #1
    peak antixa activity #1
    pulmonary thromboembolism major #1
    primigravid women labour #1
    thromboembolic complications review #1
    endothelial function pregnancy #1
    treatment copyright #1
    pge2 amniotic #1
    fvl pregnancy complications #1
    steroidal bleeding #1
    lewis fgr #1
    thrombophilia recommend #1
    interaction aboh #1
    apc pet #1
    deprived category pregnancy #1
    thrombophilia antithrombotic #1
    endothelium normal pregnancy #1
    gcs cfv #1
    716 weeks gestation #1
    total nitrites #1
    thromboxane pathophysiology #1
    fgr apcr #1
    review xxviii #1
    myelomonocytic blotting antigens #1
    underlying pte #1
    pregnancy weightloss surgery #1
    pregnancy pharmacological prophylaxis #1
    leukocytes infiltrate #1
    osteoporotic problems #1
    dinitrate labor prostaglandin #1
    reproductive age obstetricians #1
    labor acth administration #1
    “prim” study #1
    rapid reliable release #1
    complications thrombophilia #1

    Key People For Venous Thromboembolism

    Top KOLs in the world
    John A Heit
    venous thromboembolism pulmonary embolism alcohol dependence
    Harry Roger Büller
    pulmonary embolism venous thrombosis major bleeding
    Paolo Prandoni
    venous thromboembolism pulmonary embolism vein thrombosis
    Samuel Zachary Goldhaber
    pulmonary embolism atrial fibrillation major bleeding
    Martin Hendrik Prins
    venous thromboembolism pulmonary embolism intermittent claudication
    Giancarlo Agnelli
    venous thromboembolism pulmonary embolism atrial fibrillation

    Ian Andrew Greer:Expert Impact

    Concepts for whichIan Andrew Greerhas direct influence:Venous thromboembolism,  Pregnant women,  Isosorbide mononitrate,  Nitric oxide,  Fetal membranes,  Pregnancy complications,  Normal pregnancy,  Intrauterine growth restriction.

    Ian Andrew Greer:KOL impact

    Concepts related to the work of other authors for whichfor which Ian Andrew Greer has influence:Venous thromboembolism,  Pregnant women,  Immune thrombocytopenia,  Nitric oxide,  Pregnancy complications,  Preterm birth,  Polycystic ovary syndrome.



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    President and Vice Chancellor, Queen's University Belfast, Northern Ireland | Queens University, Belfast, United Kingdom; | Faculty of Medical and Human Sciences, University of Manchester, Manchester, UK | Faculty of Biology Medicine and Health, Core