Steffen Naegel: Influence Statistics

Steffen Naegel

Steffen Naegel

Department of Neurology, Westgerman Headache Center, University of Duisburg-Essen, University Hospital Essen, Essen, Germany. | Department of Neurology, University Hospital ...

Steffen Naegel: Expert Impact

Concepts for which Steffen Naegel has direct influence: Vestibular migraine , Hypnic headache , Cluster headache , Nociceptive blink reflex , Gray matter , Pain processing , Migraine patients .

Steffen Naegel: KOL impact

Concepts related to the work of other authors for which for which Steffen Naegel has influence: Vestibular migraine , Cluster headache , Trigeminal neuralgia , Chronic pain , Gray matter , Functional connectivity , Patients vm .

KOL Resume for Steffen Naegel


Department of Neurology, Westgerman Headache Center, University of Duisburg-Essen, University Hospital Essen, Essen, Germany.

Universitätsklinikum Halle (Saale), Neurologie, Halle (Saale), Germany


Department of Neurology, Martin Luther University Halle-Wittenberg, University Hospital Halle, Ernst-Grube-Str. 40, 06097, Halle (Saale), Germany


Department of Neurology, University of Duisburg-Essen, University Hospital Essen, Hufelandstr. 55, 45122, Essen, Germany


Department of Neurology and Dizziness, Vertigo Center Essen, University of Duisburg-Essen, Germany


Department of Neurology and Headache Center University of Duisburg‐Essen Essen Germany


University of Duisburg-Essen, Department of Neurology, Hufelandstr. 55, 45122 Essen, Germany +49 201 723 84385; +49 201 723 5542;


Department of Neurology and Westgerman Headache Center Essen, University Duisburg-Essen, Germany.


Department of Neurology, University Duisburg-Essen, Germany


From the Department of Neurology (D.H., C.G., S.Z., S.N., S.K., H.-C.D., Z.K., M.O.), University of Duisburg-Essen, Essen; and Interdisciplinary Pain Center (H.K.), University of Freiburg, Freiburg, Germany.


University of Duisburg-Essen, Germany.


Department of Neurology, University of Duisburg‐Essen, Essen, Germany


Department of Neurology, University of Duisburg-Essen, Hufelandstr. 55, 45122 Essen, Germany.

Prominent publications by Steffen Naegel

KOL-Index: 9689 . BackgroundCalcitonin gene related peptide (CGRP) monoclonal antibodies (mAB) are the first specific migraine prophylactic medication. Erenumab is the only CGRP mAB targeting the CGRP receptor. Clinical data regarding efficacy and tolerability of erenumab in highly therapy-refractory patients are not available, yet, although many patients treated with CGRP mAB under real world conditions ...
Known for Migraine Patients | 3 Months | Gene Peptide | Monoclonal Antibodies
KOL-Index: 9316 . BACKGROUND: Transcranial direct current stimulation (tDCS) of the primary motor cortex has been shown to modulate pain and trigeminal nociceptive processing. METHODS: Ten patients with classical trigeminal neuralgia (TN) were stimulated daily for 20 minutes over two weeks using anodal (1 mA) or sham tDCS over the primary motor cortex (M1) in a randomized double-blind cross-over design. ...
Known for Trigeminal Neuralgia | Current Stimulation | Transcranial Direct | Primary Motor Cortex
KOL-Index: 8870 . Trigeminal neuralgia (TN) is supposedly caused by an ectatic blood vessel affecting the trigeminal nerve at the root entry zone of the brain stem. Recent evidence suggests an additional central component within trigeminal pain-processing in the pathophysiology of TN. Therefore, we aimed to identify specific brain regions possibly associated with the development or maintenance of TN using ...
Known for Chronic Pain | Trigeminal Neuralgia | Gray Matter | Volume Reduction
KOL-Index: 6056 . BACKGROUND: Vestibular migraine affects 1% of the general population, and 30%-50% of all migraine patients describe occasionally associated vertigo or dizziness. We aimed to identify brain regions altered in vestibular migraine in order to evaluate the connection between migraine and the vestibular system. METHODS: Seventeen patients with definite vestibular migraine were compared to 17 ...
Known for Vestibular Migraine | Gm Volume | Brain Regions | Disease Duration

Vestibular migraine

KOL-Index: 5944 . BACKGROUND: The combination of vertigo, dizziness and balance disturbance with migraine is called vestibular migraine. Although it is estimated that up to 1% of the population suffers from this disease, it is still widely unknown and often underdiagnosed. Recently, the International Headache Society and the Báràny Society published the first joint document with mutually accepted diagnostic ...
Known for Vestibular Migraine | Differential Diagnosis | Clinical Presentation | Vertigo Dizziness
KOL-Index: 5344 . Cluster headache (CH) is characterized by recurrent episodes of excruciatingly painful, unilateral headache attacks typically accompanied by trigeminal autonomic symptoms. Due to its rhythm with alternating episodes of pain and no-pain, it is an excellent model to investigate whether structural brain changes detected by magnetic resonance based voxel-based-morphometry (VBM) reflect the ...
Known for Cluster Headache | Cortical Plasticity | Magnetic Resonance | Temporal Lobe
KOL-Index: 5244 . BACKGROUND: Hypnic headache (HH) is a rare primary headache disorder that is characterized by exclusively sleep-related headache attacks. Because of its low prevalence, clinical features and therapeutic options are widely unknown or under discussion. METHODS: Twenty patients with HH were examined and interviewed using a standardized questionnaire in regard to their clinical characteristics ...
Known for Hypnic Headache | Therapeutic Options | Clinical Characteristics | Primary Humans
KOL-Index: 5075 . BACKGROUND: Persistent postural perceptual dizziness (PPPD) is the most common vestibular syndrome in middle-aged patients. Multisensory maladjustment involving alterations of sensory response pattern including vestibular, visual and motion stimuli is thought to be a key pathophysiological correlate of this disorder. OBJECTIVE: We aimed to identify regional gray matter changes in PPPD ...
Known for Gray Matter | Pppd Patients | Perceptual Dizziness | Persistent Postural
KOL-Index: 4823 . BACKGROUND: Central facilitation of trigeminal pain processing and deficient habituation was observed in different headache and facial pain disorders. This overactivation seems to be primarily associated with chronic pain states. OBJECTIVE: To investigate the function of the trigeminal nociceptive system in patients with hypnic headache (HH). METHODS: Fifteen HH patients according ...
Known for Hypnic Headache | Nociceptive Blink Reflex | Central Facilitation | Primary Humans
KOL-Index: 4221 . Migraine is a very common disorder characterized by the combination of typical headache with associated autonomic symptoms and/or the presence of aura. Considerable advances have been made in recent years to understand the pathophysiology of migraine, which has led to improved treatment options for the acute migraine attack as well as migraine prophylaxis. Unfortunately, preventive ...
Known for Patient Preference | Treatment Migraine | Efficacy Safety | Trials Topiramate
KOL-Index: 4111 . OBJECTIVE: To investigate whether central facilitation of trigeminal pain processing is part of the pathophysiology of cluster headache (CH). METHODS: Sixty-six patients with CH (18 episodic CH inside bout, 28 episodic CH outside bout, 20 chronic CH) according to the International Classification of Headache Disorders-II classification, as well as 30 healthy controls, were investigated in a ...
Known for Cluster Headache | Trigeminal Nociception | Patients Episodic | 20 Chronic
KOL-Index: 3900 . BACKGROUND: Hypnic headache (HH) is a rare primary headache disorder characterized by strictly sleep-related headache attacks. Most patients are over the age of 50 and usually awake at the same time at night with dull bilateral head pain. The pathophysiology of this headache disorder is still enigmatic but association with rapid eye movement (REM) sleep and sleep-disordered breathing (SDB) ...
Known for Hypnic Headache | Rem Sleep | Disorders Primary | Attacks Patients

Hypnic headache

KOL-Index: 3887 . BACKGROUND: Hypnic headache (HH) is a rare primary headache disorder that is characterised by strictly sleep-related headache attacks. PURPOSE: Because of the low prevalence of this headache disorder, disease information is mainly based on case reports and small case series. This review summarises current knowledge on HH in regard to clinical presentation, pathophysiology, symptomatic ...
Known for Hypnic Headache | Primary Humans | Therapeutic Options | Case Reports
KOL-Index: 3830 . BackgroundTo enrich the hitherto insufficient understanding regarding the mechanisms of action of transcranial direct current stimulation (tDCS) in pain disorders, we investigated its modulating effects on cerebral pain processing using functional magnetic resonance imaging (fMRI).MethodsThirteen right-handed healthy participants received 20 min of 1.5 mA tDCS applied over the primary ...
Known for Pain Processing | Direct Current | Stimulation Tdcs | Motor Cortex
KOL-Index: 3639 . OBJECTIVE: Hypnic headache (HH) is a rare primary headache disorder characterized by strictly nocturnal headache attacks that mostly occur at the same time at night. The pathophysiology of this disease is poorly understood, but hypothalamic involvement was suspected as the hypothalamus represents the cerebral management center of sleep regulation and pain control. METHODS: Fourteen ...
Known for Hypnic Headache | Gray Matter | Posterior Hypothalamus | Primary Humans

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Department of Neurology, Westgerman Headache Center, University of Duisburg-Essen, University Hospital Essen, Essen, Germany. | Department of Neurology, University Hospital Halle (Saale) and University Halle-Wittenberg, Halle, Germany | Department of