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    • Paul A Mitchell
    • Paul A Mitchell: Influence Statistics

      Paul A Mitchell

      Paul A Mitchell

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      Department of Ophthalmology and Westmead Institute for Medical Research, Centre for Vision Research, University of Sydney, 2006, Camperdown, NSW, Australia | University of ...

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      Paul A Mitchell:Expert Impact

      Concepts for whichPaul A Mitchellhas direct influence:Visual impairment,Diabetic retinopathy,Cataract surgery,Blood pressure,Macular degeneration,Visual acuity,Eye study,Blue mountains.

      Paul A Mitchell:KOL impact

      Concepts related to the work of other authors for whichfor which Paul A Mitchell has influence:Diabetic retinopathy,Macular degeneration,Visual acuity,Cataract surgery,Type 2 diabetes,Optical coherence,Intraocular pressure.

      KOL Resume for Paul A Mitchell

      Year
      2022

      Department of Ophthalmology and Westmead Institute for Medical Research, Centre for Vision Research, University of Sydney, 2006, Camperdown, NSW, Australia

      2021

      Centre for Vision Research, Westmead Institute for Medical Research and Department of Ophthalmology, University of Sydney, Camperdown, NSW 2006, Australia;,

      University of Sydney, Westmead Institute for Medical Research, Sydney, Australia.

      2020

      Department of Ophthalmology, Centre for Vision Research, Westmead Institute for Medical Research, the University of Sydney, Sydney, Australia.

      Centre for Vision Research, Westmead Institute for Medical Research, 176 Hawkesbury Road Sydney, NSW 2145, Australia

      2019

      Centre for Vision Research, Department of Ophthalmology, Westmead Institute for Medical Research, University of Sydney, NSW, Australia.

      The University of Sydney, New South Wales, Australia

      2018

      Centre for Vision Research, Department of Ophthalmology, Westmead Institute for Medical Research, The University of Sydney, Sydney, NSW, Australia

      Center for Vision Research, Department of Ophthalmology and Westmead Institute for Medical Research.

      Department of Ophthalmology and Westmead Millennium Institute, University of Sydney

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      Sample of concepts for which Paul A Mitchell is among the top experts in the world.
      Concept World rank
      myopic retinopathy #1
      earlyte #1
      studies pegaptanib #1
      aniso astigmatism #1
      bmes bmesi #1
      undiagnosed visually #1
      normative visual acuity #1
      length corneal #1
      associations retinal emboli #1
      ranibizumab treatment laser #1
      cataract surgery participants #1
      iop iop locus #1
      tests disability glare #1
      prior ranibizumab laser #1
      2335 751 #1
      persons 80 years #1
      lens retrodots #1
      lower dairy products #1
      smoking control study #1
      risk early amd #1
      concurrent vision #1
      geographic atrophy observations #1
      participants examined #1
      stereoacuity tests #1
      renal function incidence #1
      bmes #1
      cataract incidence progression #1
      sham baseline #1
      older cohort followup #1
      cdr age #1
      therapeutic endorsement #1
      15year incidence progression #1
      95 05mg #1
      146174 #1
      workplace noise #1
      methodsaries #1
      anisometropia aniso #1
      questionnaires tomography #1
      awareness amd #1
      age‐related hearing loss #1
      nuclear cataract smoking #1
      myopic refractive shift #1
      level bevacizumab #1
      heterotropia #1
      association tgif #1
      cad amd #1
      epha2 congenital cataract #1
      4118 children #1
      rnfl optic disc #1
      incident early amd #1
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      Prominent publications by Paul A Mitchell

      KOL-Index: 27976

      OBJECTIVE: To demonstrate superiority of ranibizumab 0.5 mg monotherapy or combined with laser over laser alone based on mean average change in best-corrected visual acuity (BCVA) over 12 months in diabetic macular edema (DME).

      DESIGN: A 12-month, randomized, double-masked, multicenter, laser-controlled phase III study.

      PARTICIPANTS: We included 345 patients aged ≥18 years, with type 1 or 2 diabetes mellitus and visual impairment due to DME.

      METHODS: Patients were randomized to ...

      Known for Ranibizumab Monotherapy | Laser Patients | Monoclonal Antibodies | Diabetic Macular Edema | Baseline Month
      KOL-Index: 19491

      IMPORTANCE: Few data are available on relative changes in vision-related function after treatment for diabetic macular edema (DME).

      OBJECTIVE: To determine the impact of intravitreal ranibizumab, 0.5 mg, compared with laser on patient-reported visual function.

      DESIGN: Phase 3, randomized, double-masked, 12-month study (RESTORE).

      SETTING: Outpatient retina practices in Australia, Canada, and Europe.

      PARTICIPANTS: Patients 18 years or older with type 1 or 2 diabetes mellitus and visual ...

      Known for Ranibizumab Treatment | Diabetic Macular Edema | Laser Patients | Visual Function | 12 Months
      KOL-Index: 18512

      PURPOSE: To describe the prevalence and causes of visual impairment and blindness in an urban Indian population.

      DESIGN: Population-based study.

      PARTICIPANTS: Ethnic Indians aged more than 40 years living in Singapore.

      METHODS: Participants underwent standardized ophthalmic assessments for visual impairment and blindness, defined using best-corrected visual acuity (BCVA) and presenting visual acuity (PVA), according to US and modified World Health Organization (WHO) definitions.

      MAIN ...

      Known for Visual Impairment | Singapore India | Bilateral Blindness | Eye Study | Aged Prevalence
      KOL-Index: 18129

      Importance: Geographic atrophy (GA) secondary to age-related macular degeneration is a leading cause of visual disability in older individuals. A phase 2 trial suggested that lampalizumab, a selective complement factor D inhibitor, reduced the rate of GA enlargement, warranting phase 3 trials.

      Objective: To assess the safety and efficacy of lampalizumab vs sham procedure on enlargement of GA.

      Design, Setting, and Participants: Two identically designed phase 3 double-masked, randomized, ...

      Known for Spectri Phase | Geographic Atrophy | Complement Factor | Lesion Area | Efficacy Safety
      KOL-Index: 17674

      OBJECTIVE: To evaluate long-term efficacy and safety profiles during 3 years of individualized ranibizumab treatment in patients with visual impairment due to diabetic macular edema (DME).

      DESIGN: Phase IIIb, multicenter, 12-month, randomized core study and 24-month open-label extension study.

      PARTICIPANTS: Of the 303 patients who completed the randomized RESTORE 12-month core study, 240 entered the extension study.

      METHODS: In the extension study, patients were eligible to receive ...

      Known for Extension Study | Ranibizumab Treatment | 3 Years | Diabetic Macular Edema | Injections Laser
      KOL-Index: 17658

      PURPOSE: To describe the prevalence and risk factors of diabetic retinopathy in Asian Malays.

      DESIGN: Population-based cross-sectional study.

      PARTICIPANTS: Persons with diabetes of Malay ethnicity aged 40 to 80 years in Singapore.

      METHODS: Diabetes mellitus was defined as random glucose of 11.1 mmol/l or more, use of diabetic medication, or a physician diagnosis of diabetes. Retinal photographs taken from both eyes were graded for diabetic retinopathy using the modified Airlie House ...

      Known for Diabetic Retinopathy | Diabetes Prevalence | Singapore Malay | Macular Edema | 95 Increase
      KOL-Index: 16979

      PURPOSE: To determine the prevalence, incidence, and change in refractive errors for Australian schoolchildren and examine the impact of ethnicity and sex.

      DESIGN: Population-based cohort study.

      PARTICIPANTS: The Sydney Adolescent Vascular and Eye Study, a 5- to 6-year follow-up of the Sydney Myopia Study, examined 2760 children in 2 age cohorts, 12 and 17 years. Longitudinal data were available for 870 and 1202 children in the younger and older cohorts, respectively.

      METHODS: Children ...

      Known for Myopia Children | East Asian | Prevalence Incidence | Eye Study | Follow Studies
      KOL-Index: 16751

      PURPOSE. To determine the prevalence of amblyopia and strabismus in young Singaporean Chinese children. METHODS. Enrolled in the study were 3009 Singaporean children, aged 6 to 72 months. All underwent complete eye examinations and cycloplegic refraction. Visual acuity (VA) was measured with a logMAR chart when possible and the Sheridan-Gardner test when not. Strabismus was defined as any manifest tropia. Unilateral amblyopia was defined as a 2-line difference between eyes with VA < ...

      Known for Amblyopia Strabismus | Chinese Children | Visual Acuity | 48 Months | Cycloplegic Refraction
      KOL-Index: 16745

      PURPOSE: To assess the 15-year incidence and progression of reticular drusen and associations of this lesion with age-related macular degeneration (AMD) risk factors.

      DESIGN: Population-based cohort.

      PARTICIPANTS: Blue Mountains Eye Study participants (n = 3654) 49 years of age and older attended baseline examinations; of these, 75.8%, 76.7%, and 56.1% of survivors attended 5-year, 10-year, and 15-year follow-up examinations, respectively.

      METHODS: Color retinal photographs were obtained ...

      Known for Reticular Drusen | Incidence Progression | Late Amd | Age Macular | Australian Cohort
      KOL-Index: 16671

      PURPOSE: To describe the prevalence and risk factors for myopia and other refractive errors in an urban Malay population in Singapore.

      DESIGN: Population-based, cross-sectional study.

      PARTICIPANTS: Persons of Malay ethnicity, between 40 and 80 years of age, living in Singapore.

      METHODS: Refractive error was determined by subjective refraction and if unavailable by autorefraction. Data were analyzed for 2974 adults without previous cataract surgery and who had right eye refraction data. ...

      Known for Singapore Malay | Refractive Errors | Prevalence Myopia | Astigmatism Anisometropia | Subjective Refraction
      KOL-Index: 16452

      OBJECTIVE: To evaluate the 2-year safety and efficacy of ranibizumab 0.5 mg in diabetic macular edema (DME).

      DESIGN: Twenty-four-month, open-label, multicenter, Phase IIIb extension study.

      PARTICIPANTS: Two hundred forty of 303 patients with visual impairment due to DME who completed the RESTORE core study and entered the extension.

      METHODS: All patients were eligible to receive ranibizumab 0.5 mg pro re nata (PRN) from month 12 (end of core study) to month 36 based on best-corrected ...

      Known for Extension Study | Ranibizumab Laser | Macular Edema | Bcva Patients | Injections Prior
      KOL-Index: 16224

      PURPOSE: To describe the prevalence of age-related degeneration (AMD) in a rural Chinese population and to assess its associations with age, gender, and smoking.

      DESIGN: Population-based cross-sectional.

      PARTICIPANTS: Persons aged 30+ years, recruited between October 2006 and October 2007, from Yongnian County, Handan, Hebei Province, China.

      METHODS: All participants underwent a standardized interview and comprehensive eye examinations, including digital retinal photography of both eyes. ...

      Known for Rural Chinese | Handan Eye Study | Early Amd | Macular Degeneration | Prevalence Age
      KOL-Index: 15873

      OBJECTIVE: To quantify the relationship between myopia and open-angle glaucoma, ocular hypertension (OH), and intraocular pressure (IOP) in a representative older population.

      DESIGN: Cross-sectional population-based study of 3654 Australians 49 to 97 years of age.

      METHODS: Subjects with any myopia (> or =-1.0 diopter [D]) were identified by a standardized subjective refraction and categorized into low myopia (> or =-1.0 D to <-3.0 D) or moderate-to-high myopia (> or =-3.0 D). Glaucoma ...

      Known for Myopia Glaucoma | Intraocular Pressure Iop | Eye Study | Ocular Hypertension | Factors Visual
      KOL-Index: 15865

      OBJECTIVE: To compare the prevalence and risk factors for myopia in 6- and 7-year-old children of Chinese ethnicity in Sydney and Singapore.

      METHODS: Two cross-sectional samples of age- and ethnicity-matched primary school children participated: 124 from the Sydney Myopia Study and 628 from the Singapore Cohort Study on the Risk Factors for Myopia. Cycloplegic autorefraction was used to determine myopia prevalence (spherical equivalent < or = -0.5 diopter). Lifestyle activities were ...

      Known for Prevalence Myopia | Chinese Ethnicity | Singapore Children | Outdoor Activities | Spherical Equivalent

      Key People For Visual Impairment

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      Paul A Mitchell
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      Department of Ophthalmology and Westmead Institute for Medical Research, Centre for Vision Research, University of Sydney, 2006, Camperdown, NSW, Australia | University of Sydney (Westmead Institute for Medical Research), Sydney, NSW, Australia | Cen

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