Jean Pierre Lhuintre: Influence Statistics

Jean Pierre Lhuintre

Jean Pierre Lhuintre

Pharmacochimie - U.F.R. de Médecine et Pharmacie -76803 Saint Etienne du Rouvray Cedex - France | Pharmacochimie, Faculty of Medicine of Rouen, BP 97, 76803 ...


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Jean Pierre Lhuintre: Expert Impact

Concepts for which Jean Pierre Lhuintre has direct influence: Voluntary intake , Serotonin uptake , Ethanol intake , Ethanol rats , Weaned alcoholics , Alcohol intake , Gaba transmission .

Jean Pierre Lhuintre: KOL impact

Concepts related to the work of other authors for which for which Jean Pierre Lhuintre has influence: Alcohol dependence , Ethanol intake , Gabab receptor , Proctalgia fugax , Nucleus accumbens , Naltrexone acamprosate , Serotonin uptake .

KOL Resume for Jean Pierre Lhuintre

Year
1991

Pharmacochimie - U.F.R. de Médecine et Pharmacie -76803 Saint Etienne du Rouvray Cedex - France

1990

Pharmacochimie, Faculty of Medicine of Rouen, BP 97, 76803 Saint‐Étienne‐du‐Rouvray, France

1987

(GRAP), Groupe de recherche sur l'alcoolisme et sa prévention Faculté de Medecine de Rouen, 76800 Saint-Etienne du Rouvray, France

1986

Department of Pharmacology, Faculty of Medicine of Rouen, B.P. 97 76800, Saint-Etienne du Rouvray, France

1985

Department of Pharmacology, Faculty of Medicine of Rouen, B.P. 97, 76800 Saint-Etienne du Rouvray, France

1984

Laboratoire de Pharmacologie, Faculté de Médecine de ROUEN, BP 97, 76800 St Etienne du Rouvray, France

Prominent publications by Jean Pierre Lhuintre

KOL-Index: 8831 . Adult male Long Evans were selected as ethanol preferring rats (DR) during 28 days. After this period, they were daily IP injected during 14 days with one of the next drugs: diazepam 1 mg.kg-1, alprazolam 1 mg.kg-1 (benzodiazepines), progabide 25 mg. kg-1 (GABA A and B agonist), nipecotic acid 150 mg.kg-1 (GABA uptake inhibitor), muscimol 0.2 mg.kg-1 (GABA A agonist), AOAA 10 mg.kg-1 (GABA ...
Known for Ethanol Intake | Gaba Transmission | Rats Receptors | Benzodiazepine Receptor
KOL-Index: 6853 . Ethanol preferring rats were selected and showed a constant voluntary intake of a 12 percent ethanol solution during 14 days (about 5 g/kg body weight daily). Analysis of 3H serotonin uptake by striatal synaptosomes showed that steady state 3H serotonin synaptosomal levels were lower in alcohol preferring rats. Grouping these rats (5 per cage) reduced both voluntary intake of ethanol and ...
Known for Voluntary Intake | Serotonin Uptake | Ethanol Rats | Striatal Synaptosomes
KOL-Index: 6837 . The effects of some derivatives of homotaurine (3 APS), the well known GABA agonist, were tested on the voluntary intake of ethanol by rats. Spontaneously ethanol drinking rats (DR) were selected and had a constant voluntary intake of ethanol by rats. Spontaneously ethanol drinking rats (DR) were selected and had a constant voluntary intake of a 12% ethanol solution (VIE) during 14 days ...
Known for Voluntary Intake | Ethanol Rats | Gaba Receptors | Calcium Acetylhomotaurine
KOL-Index: 6269 . After they had been weaned off alcohol in hospital 85 severe alcoholics (above 200 g alcohol/day) were included in a double-blind study of calcium bis acetyl homotaurine (Ca AOTA, 25 mg/kg/day), a new gamma-aminobutyric acid agonist, versus placebo. Patients were treated as outpatients during the 3-month study. The only other treatment that patients received was meprobamate, 800 to 1200 ...
Known for Weaned Alcoholics | Acetyl Homotaurine | Prevent Relapse | Placebo Patients
KOL-Index: 4836 . The kinetic parameters of 3H-paroxetine binding and 3H-serotonin uptake were studied in platelets of alcoholic patients. There was no difference between alcoholic and non alcoholic subjects in 3H-paroxetine binding. When binding and 3H-serotonin uptake were studied, in the same plasma of the same subjects, the Vmax of serotonin uptake was increased in alcoholics. The data confirm the ...
Known for Serotonin Uptake | Alcoholic Patients | Paroxetine Binding | Platelets 3h
KOL-Index: 4391 . The kinetics of 3H serotonin platelet uptake were studied in alcoholics and former alcoholics to see whether differences found between alcohol-preferring and non-preferring rats could be reproduced in man. Three groups of patients were studied: 10 dependent alcoholics on admission for treatment; 10 dependent alcoholics after 20 days of treatment; 8 former dependent alcoholics, abstinent ...
Known for Alcohol Dependence | Biological Marker | Vitro Techniques | Serotonin Uptake
KOL-Index: 3200 . 3H-nipecotic acid (3H-NIP) binding to GABA uptake recognition sites was studied in the hippocampus of 3 groups of male, Long Evans rats: Group 1: ethanol-naive rats (ENR); Group II: ethanol-preferring rats (DR) and non-preferring rats (NDR), which had consumed about 5 g.kg-1.d-1 and 1 g-1.d-1 of alcohol respectively in the form of a 12% ethanol solution prior to 3H-NIP binding analysis; ...
Known for Gaba Uptake | Hippocampus Male | Aminobutyric Acid | Affinity 3h
KOL-Index: 2170 . Ethanol preferring and non preferring rats were selected. Ethanol preferring rats showed a constant voluntary intake of a 12% ethanol solution during 14 days (about 5 g/kg body weight daily) while the non preferring rats drank less than 1 g/kg body weight daily. Preferring rats were daily IP injected with 5 or 10 mg/kg of nomifensine, an inhibitor of dopamine uptake. Their intake of ...
Known for Dopamine Uptake | Nomifensine Rats | Alcohol Drinking | Corpus Striatum
KOL-Index: 924
Known for Proctalgia Fugax | Diltiazem Female Humans

Key People For Voluntary Intake

Top KOLs in the world
#1
R C Campling
voluntary intake alimentary tract artificial diets
#2
Peter J Van Soest
dietary fiber ragusano cheese cell wall
#3
Clive C Balch
fat content dairy cows calcium salts
#4
Kenneth L Blaxter
fatty acids environmental temperature heat production
#5
Dennis J Minson
voluntary intake pangola grass digitaria decumbens
#6
F W Wainman
fatty acids environmental temperature heat production

Pharmacochimie - U.F.R. de Médecine et Pharmacie -76803 Saint Etienne du Rouvray Cedex - France | Pharmacochimie, Faculty of Medicine of Rouen, BP 97, 76803 Saint‐Étienne‐du‐Rouvray, France | (GRAP), Groupe de recherche sur l'alcoolisme et sa prévent