Jinghua Chen

Jinghua Chen

School Of Pharmaceutical Sciences, Jiangnan University, Wuxi 214122, Jiangsu, China. Electronic Address: Chenjinghua@jiangnan.edu.cn.

Direct Impact

Concepts for which Jinghua Chen has direct influence:

infusion chemotherapy
hepatocellular carcinoma
hepatic arterial
haic oxaliplatin
milan criteria
dna loads
fluorouracil leucovorin

External impact

Concepts related to the work of other authors for which Jinghua Chen has influence:

gut microbiome
neoadjuvant chemotherapy
birth weight
blood loss
lymph node
major complications
acute liver

Prominent publications by Jinghua Chen

KOL-Index: 64 Background: We analyzed bronchopulmonary carcinoid tumor (BPC) patients receiving resection from the Surveillance, Epidemiology, and End Results (SEER) database to identify the predictive factors of their survival. Then, we developed and validated nomograms to predict overall survival (OS) and cancer-specific survival (CSS) in BPC patients. Methods: BPC patients registered in the SEER ...
Known for
Bpcs | Css Bpc | Predicting Long | Concordance Indexes
KOL-Index: 49 Multidrug resistance (MDR) is the main challenge faced by cancer chemotherapy. Drug-conjugate offers a promising strategy for breast cancer therapy. In this regard, we developed a DNVM multifunctional drug delivery system by crosslinking doxorubicin (DOX) and vitamin E succinate (VES) with a pH-sensitive hydrazone bond and then encapsulated the DOX-NN-VES prodrug into pH-sensitive hyaluronic ...
Known for
P-Gp | Dox Ves | Hod | Breast Cancer Therapy
KOL-Index: 46 Objective: To investigate the impact of postoperative infectious complications (POI) on the long-term outcomes of patients with colorectal cancer liver metastasis (CRLM) after simultaneous resection of colorectal cancer and liver metastases. Methods: Four hundred seventy-nine CRLM patients receiving simultaneous resection between February 2010 and February 2018 at our hospital were enrolled. ...
Known for
Multivariate Poi | Crlm Simultaneous | Term Colorectal | Hepatic Portal Occlusion
KOL-Index: 43 BACKGROUND: This study sought to evaluate the effects of pre-neoadjuvant chemotherapy lactate dehydrogenase (pre-NAC LDH) levels, preoperative LDH levels, and changes in LDH levels on the pathological response and outcomes of colorectal liver metastases (CRLM) patients treated with liver resection after NAC. METHODS: This study included 152 colorectal CRLM patients, who underwent NAC ...
Known for
Response Postoperative | Clavien-Dindo Classification | Regression Grade | Demographic Clinicopathological
KOL-Index: 41 Background: Although lymph node dissection (LND) has been commonly used for patients with bronchopulmonary carcinoids (PCs), the prognostic values of the positive lymph node ratio (PLNR) and the number of removed nodes (NRN) remain unclear. Methods: Patients with resected PCs were identified in the Surveillance, Epidemiology, and End Results (SEER) database (2010-2015). The optimal cut-off ...
Known for
≥13 | Lnd | Cox Css | Resected Pcs
KOL-Index: 40 OBJECTIVE: The optimal surgical management for 10- to 20-mm rectal neuroendocrine tumors (RNET) is still a matter of debate. This study aimed to explore the optimal surgical approach for 10- to 20-mm RNET by comparing the outcomes between local excision and radical resection. METHOD: We extracted clinicopathological information of 10- to 20-mm RNET from the Surveillance, Epidemiology, and ...
Known for
10- | Comparable Survival | 531 Rnet | Benefit Local
KOL-Index: 36 Background Previous studies arguably associated poor embryo morphology with low birthweight in singletons following single embryo transfer. However, the association between specific morphological features on the cleavage stage and birthweight is still less known. The purpose of the study was to investigate whether embryo morphological features at the cleavage stage affect birthweight ...
Known for
Morphology Fragmentation | Stage Birthweight | Morphological Parameters | Blastomere Number
KOL-Index: 28 INTRODUCTION: The extent of optimal gastric resection for proximal gastric cancer (PGC) continues to remain controversial, and a final consensus is yet to be met. The current study aimed to compare the perioperative outcomes, postoperative complications, and overall survival (OS) of proximal gastrectomy (PG) versus total gastrectomy (TG) in the treatment of PGC through a meta-analysis. ...
Known for
Retrieved Lymph Nodes | Wmd | Optimal Gastric Resection | Irrespective
KOL-Index: 26 BackgroundAlzheimer’s disease has become a public health crisis globally due to its increasing incidence. The purpose of this study was to establish an early warning model using artificial neural network (ANN) for early diagnosis of AD and to explore early sensitive markers for AD.MethodsA population based nested case-control study design was used. 89 new AD cases with good compliance who ...
KOL-Index: 26 Abstract Piwi-interacting RNAs (piRNAs) are small RNAs predominantly expressed in germ cells that are critical for gametogenesis in various species. However, PIWI-deficient female mice are fertile and mouse oocytes express a panel of small RNAs that do not appear widely representative of mammals, and piRNA function in the oogenesis of other mammals has therefore remained elusive. Recent ...
Known for
Piwi-Interacting Rnas | Deficient Golden Hamsters | Piwil1 Mutant Oocytes | Hamster Piwi

School of Pharmaceutical Sciences, Jiangnan University, Wuxi 214122, Jiangsu, China. Electronic address: chenjinghua@jiangnan.edu.cn.

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