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  • Marco Meleti

    Prominent publications by Marco Meleti

    KOL Index score: 15671

    Osteonecrosis of the jaw (ONJ) in patients on long-term bisphosphonate Therapy (BPT) has been reported with increasing frequency in literature over the past 4 years. Therapy for this condition is still a dilemma. Temporary suspension of BPT offers no short-term benefits; hyperbaric oxygen has no proven efficacy and therefore is not recommended. Intermittent or continuous antibiotic therapy with surgical debridement can be beneficial to palliate the symptoms. Er:YAG laser can be used to ...

    Also Ranks for: Yag Laser |  surgical approach |  bisphosphonate therapy |  medical treatment |  onj patients
    KOL Index score: 10483

    Hyperplastic fibro-epithelial lesions are the most common tumor-like swellings in the mouth. The neodymium yttrium aluminium garnet (Nd:YAG) laser appears to be useful for the surgical treatment of these lesions. Some controversies of laser surgery concern the accuracy of pathological diagnosis as well as the control of thermal damage on the target tissue. The aim of this study was to establish if the thermal changes induced by the Nd:YAG laser may affect the histopathological diagnosis ...

    Also Ranks for: Yag Laser |  oral mucosa |  histological analysis |  surgical treatment |  histopathological diagnosis
    KOL Index score: 10412

    BACKGROUND DATA: The management of bisphosphonate-related osteonecrosis of the jaws (BRONJ) is still controversial.

    OBJECTIVE: The purpose of this study was to compare surgical and nonsurgical approaches to the treatment of BRONJ and the possible usefulness of Nd:YAG and Er:YAG lasers.

    METHODS: One hundred and twenty-eight patients (33 males, 95 females; 52 with diagnosis of multiple myeloma, 53 with diagnosis of bone metastasis, and 23 with diagnosis of osteoporosis) affected by BRONJ ...

    Also Ranks for: Treatment Bronj |  g2 g3 |  clinical improvement |  laser therapy |  treated sites
    KOL Index score: 9688

    OBJECTIVE: To research an efficient treatment for the management of bisphosphonate-associated osteonecrosis.

    BACKGROUND DATA: Necrosis of the jawbone has recently been described in association with systemic bisphosphonate therapy with drugs including zoledronic acid, pamidronate, and alendronate. The extent and clinical characteristics of bisphosphonate-associated osteonecrosis (BON) of the jaw are extremely variable, and range from the presence of fistulae in the oral mucosa or ...

    Also Ranks for: Laser Biostimulation |  medical therapy |  treatment jaw |  clinical experience |  presence pus
    KOL Index score: 9191

    Many dental bleaching techniques are now available, several of them using a laser source. However, the literature on the exact role of coherent light in the biochemical reaction of the whitening process is very discordant. The aims of this in vitro study were: (1) to compare two different laser sources, a KTP laser with a wavelength of 532 nm and a diode laser with a wavelength of 808 nm, during dental bleaching, and (2) to investigate the relationships among changes in gel temperature, ...

    Also Ranks for: Diode Laser |  dental bleaching |  hydrogen peroxide |  vitro study |  gel temperature
    KOL Index score: 8542

    OBJECTIVE: Trauma during dental surgery is a predisposing factor for bisphosphonates (BP)-related osteonecrosis of the jaws (BRONJ). However, about 40% of cases of BRONJ are not related to dental invasive procedures, being probably associated to endodontic or periodontal infections. Extraction of non-treatable teeth is considered a reliable choice, to improve symptoms and to reduce the risk of BRONJ. Here we report our experience of tooth extractions in patients under oral or intravenous ...

    Also Ranks for: Tooth Extractions |  level laser |  antibiotic treatment |  yag low |  oral medicine
    KOL Index score: 8172

    Jaw bone necrosis is a clinical condition associated with defects in vascularization of the maxilla or the mandibular bone, usually present following head and neck radiotherapy and/or oral surgical interventions. Bisphosphonates are synthetic analogues of pyrophosphate used in the treatment of patients with hypercalcemia as a result of malignancy, bone metastasis and for the treatment of other disorders such as metabolic bone diseases, Paget's disease and osteoporosis. Over last 10 ...

    Also Ranks for: Jaw Bone |  dental extraction |  multiple myeloma patients |  bisphosphonate therapy |  pagets disease
    KOL Index score: 7967

    INTRODUCTION: Dentoalveolar surgery including tooth extractions and dental implants placement is considered the major risk factor for developing medication-related osteonecrosis of the jaw (MRONJ).In this study, a patient series of MRONJ around dental implants were carefully analyzed to describe the findings and to assess the possible risk factors.

    METHODS: Fifteen patients with peri-implant bone osteonecrosis were selected out of a group of 250 patients (6%). Patients were divided into ...

    Also Ranks for: Dental Implants |  mronj patients |  implant placement |  medicationrelated osteonecrosis |  jaw bone
    KOL Index score: 7434

    Bisphosphonates (BPs) are used to treat metabolic bone diseases, such as osteoporosis. In this study the occurrence of bisphosphonates-related osteonecrosis of the jaws (BRONJ) is reported in 25 patients who received BP therapy for osteoporosis with different drug schedules. From June 2005 to May 2009, 25 patients affected by BRONJ were observed. A history of oral surgery was reported for 18 patients (72%). Of the 22 patients treated by the authors, 20 (91%) recorded healing improvement ...

    Also Ranks for: Patients Osteoporosis |  jaws bronj |  oral surgery |  laser therapy |  aged osteonecrosis
    KOL Index score: 7405

    The term "pigmentation of the oral mucosa" is applied to a wide range of lesions or conditions featuring a change of color of oral tissues. Lesions not associated with an accumulation of pigment (e.g., Fordyce spots) are usually not classified as pigmented lesions. Two groups of pigmented lesions of the oral mucosa are recognized: 1) melanin-associated lesions, including racial pigmentations, melanotic macules, melanocytic nevi, and malignant melanoma; and 2) nonmelanin-associated ...

    Also Ranks for: Oral Mucosa |  pigmented lesions |  diagnosis management |  melanotic macules |  fordyce spots
    KOL Index score: 6681

    Since the introduction of laser in clinical practice, different wavelengths have been used for oral surgery on the basis of the different characteristics and affinities of each one. The aim of this study was a comparison of different laser wavelengths in relation to both thermal increase and “histological quality” in a model of soft tissue surgery procedures. Thermal evaluation was realized, during laser-assisted surgery excision performed on a bovine tongue, by a thermal camera device ...

    Also Ranks for: Histological Evaluation |  yag laser |  oral surgery |  vivo study |  surgical procedures
    KOL Index score: 6615

    The osteonecrosis of the jaws (ONJ) is an adverse side effect of long-term bisphosphonate therapy (BPT) firstly described in 2003. The aetiology of BRONJ remains unknown, and the pathogenesis seems multifactorial and related to several local or general factors. Many expert panel developed preventive protocols to facilitate specialists involved in the multidisciplinary management of BRONJ patients. In this paper, we present a concise review of the literature, and we report the experience ...

    Also Ranks for: Osteonecrosis Jaws |  multiple myeloma |  tooth extraction |  surgical approach |  laser therapy
    KOL Index score: 6506

    BACKGROUND: Treatment of head and neck mucosal melanoma remains a challenge. Surgery has traditionally been the main therapeutic approach. The role of postoperative radiotherapy has never been clearly established.

    METHODS: The experience with a group of 42 patients (16 males, 26 females) with a primary head and neck mucosal melanoma is reported.

    RESULTS: Eleven of 19 patients (57.9%) receiving surgery alone developed a regional lymphatic metastasis. For patients receiving postoperative ...

    Also Ranks for: Postoperative Radiotherapy |  mucosal melanoma |  patients surgery |  female head |  distant metastases
    KOL Index score: 6180

    Medication-related osteonecrosis of the jaws (MRONJ) is an adverse side effect of several drug therapies, including bisphosphonates (BPs). Osteonecrosis of the jaw specifically related to BP therapy is usually referred to using the acronym BRONJ. However, no consensus has yet been reached regarding the most appropriate management of BRONJ. The greatest success rates have been recorded with surgical removal of necrotic bone. In particular, erbium:yttrium-aluminum-garnet (Er:YAG) ...

    Also Ranks for: Histopathologic Evaluation |  necrotic bone |  medicationrelated osteonecrosis |  surgical removal |  clinical differences


    Marco Meleti: Influence Statistics

    Sample of concepts for which Marco Meleti is among the top experts in the world.
    Concept World rank
    detection salivary molecules #1
    reference points afir #1
    bacterialderived metabolites identification #1
    sublingual saliva detection #1
    neoangiogenesis hyperkeratosis #1
    histopathological features nmsc #1
    alteration afir #1
    emission neoplastic #1
    elastosis neoangiogenesis #1
    hyperkeratosis neoangiogenesis #1
    sublingual metabolites #1
    saliva subtypes #1
    specific salivary cytokines #1
    fluid ideal candidate #1
    metabolites submandibular #1
    metabolic profiles parotid #1
    hypo fluorescent #1
    afir fibrosis #1
    autofluorescence nmscs #1
    features nmsc #1
    intensity histological features #1
    points afir #1
    neoangiogenesis fibrosis #1
    features hyperkeratosis #1
    frequent cytokines #1
    phenomenon autofluorescence #1
    afir scc #1
    healthy tissues hyperkeratosis #1
    afir autofluorescence #1
    search salivary biomarkers #1
    afir intensity #1
    intensity fluorescence emission #1
    spectrophotometric devices #1
    interazioni #2
    fluorophores oral mucosa #2
    yag laserassisted surgery #2
    mandible conservative excision #2
    width keratin #2
    cold blade #2
    qmr scalpel #2
    keratin layer velscope #2
    histological features width #2
    decades velscope #2

    Key People For Yag Laser

    Top KOLs in the world
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    yag laser phase function biological tissue
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    R Rox Anderson
    photodynamic therapy laser treatment human skin

    Marco Meleti:Expert Impact

    Concepts for whichMarco Meletihas direct influence:Yag laser,  Laser welding,  Thermal increase,  Gingival overgrowth,  Oral mucosa,  Tooth extractions,  Surgical approach,  Systemic diseases.

    Marco Meleti:KOL impact

    Concepts related to the work of other authors for whichfor which Marco Meleti has influence:Yag laser,  Oral mucosa,  Osteonecrosis jaw,  Zoledronic acid,  Surgical treatment,  Tooth extraction,  Dental implants.



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    Department of Medicine and Surgery, University of Parma, via Gramsci, 14, 43126 Italy. | DDS, PhD. Centro Universitario di Odontoiatria, Department of Medicine and Surgery, Oral Medicine and Laser Surgery Unit, University of Parma, Parma, Italy. | Ce