Xiaojun Chen: Influence Statistics

Xiaojun Chen

Xiaojun Chen

Department of Gynecology, Obstetrics and Gynecology Hospital, Fudan University, No. 419, Fangxie Road, 200011, Shanghai, People’s Republic of China | College of Computer ...

Xiaojun Chen: Expert Impact

Concepts for which Xiaojun Chen has direct influence: Extubation failure , Knee arthroscopy , Soluble fiber , Peritoneal fibrosis , Chinese sturgeon , Foxl2 gene , Fracture toughness .

Xiaojun Chen: KOL impact

Concepts related to the work of other authors for which for which Xiaojun Chen has influence: Cervical cancer , Heat stress , Nonsmooth equations , Mesenchymal stem , Inflammatory bowel disease , Newton method , Artificial intelligence .

KOL Resume for Xiaojun Chen

Year
2022

Department of Gynecology, Obstetrics and Gynecology Hospital, Fudan University, No. 419, Fangxie Road, 200011, Shanghai, People’s Republic of China

Obstetrics and Gynecology Hospital of Fudan University

2021

Institute of Information Engineering, Chinese Academy of Sciences, Beijing, China

Nanjing Tech University

College of Chemistry and Molecular Engineering

Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota.

2020

Yikesite (Beijing) Biopharma Development LLC, Suite B-306, 5 Kaituo Rd, Haidian District, Beijing, 100085, China

Institute of Nuclear Physics and Chemistry

Mianyang

2019

College of Computer Science and Technology, Zhejiang University, Hanghzou, People's Republic of China

Department of Gynecology, Obstetrics and Gynecology, Hospital of Fudan University, Shanghai,

Shenzhen University

Prominent publications by Xiaojun Chen

KOL-Index: 15526 . BACKGROUND: The management of latent Mycobacterium tuberculosis infection is a new priority action for the WHO End Tuberculosis (TB) Strategy. However, national guidelines on latent tuberculosis infection testing and treatment have not yet been developed in China. Here, we present the results from the 2-year follow-up of a study that aimed to track the development of active disease in ...
Known for Active Tuberculosis | Rural China | Latent Infection | 100 Personyears
KOL-Index: 10398 . Mesenchymal stem cells (MSCs), which are poorly immunogenic and have potent immunosuppressive activities, have emerged as a promising candidate for cellular therapeutics for the treatment of disorders caused by abnormal immune responses. In this study we investigated whether human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) could ameliorate colitis in a trinitrobenzene ...
Known for Mesenchymal Stem | Umbilical Cord | Huc Mscs | Colitis Colon
KOL-Index: 8865 . Ubiquitin ligases play important roles in immune regulation. The human RNF114 (RING finger protein 114), an ubiquitin ligase, was recently reported to be involved in immune response to double-stranded RNA in disease pathogenesis. Here, we identified a RNF114 homolog in Chinese sturgeon (Acipenser sinensis) and investigated its potential role in immune response. The full-length cDNA of ...
Known for Chinese Sturgeon | Ring Finger Protein | Signaling Pathway | Immune Response
KOL-Index: 8476 . Background: Tripartite motif-containing protein 11 (TRIM11) is one of the E3 ubiquitin ligases, which is upregulated in several human tumors. Meanwhile, the detailed function of TRIM11 remains unclear in breast cancer cells. Purpose: The purpose of the present study is to analyze the biological function of TRIM11 and identify its potential signaling pathway in breast cancer cells. Patients ...
Known for Breast Cancer | Biological Function | Trim11 Promotes | Signaling Pathway
KOL-Index: 7910 . In the past decades, hepatocellular carcinoma (HCC) has been receiving increased attention due to rising morbidity and mortality in both developing and developed countries. Koumine, one of the significant alkaloidal constituents of Gelsemium elegans Benth., has been regarded as a promising anti-inflammation, anxiolytic, and analgesic agent, as well as an anti-tumor agent. In the present ...
Known for Hepatocellular Carcinoma | Cell Proliferation | Ros Production | Mapk Signaling
KOL-Index: 7737 . We have previously reported that the accumulation of IL-17-producing cells could mediate tumor protective immunity by promoting the migration of NK cells, T cells and dendritic cells in esophageal squamous cell carcinoma (ESCC) patients. However, there were no reports concerning the effect of IL-17A on tumor infiltrating B cells. In this study, we investigated the accumulation of CD20+ B ...
Known for Squamous Cell | Il17a Migration | Carcinoma Escc | Tumor Protective Immunity
KOL-Index: 7728 . Programmed cell death 4 (PDCD4) is a novel tumor suppressor, which is involved in the initiation and progression of cancers. However, the role of PDCD4 in hepatocellular carcinoma (HCC) has not been reported. The aim of this study was to investigate the molecular mechanism and clinical significance of PDCD4 inactivation in HCC.The mRNA levels of PDCD4 in HCC tissues and adjacent nontumor ...
Known for Tumor Carcinoma | Methylation Status | Programmed Cell Death | Suppressor Gene
KOL-Index: 7630 . Ovarian cancer is one of the common female malignant tumors. The early diagnosis and treatment of ovarian cancer has been a research hotspot. Therefore, we aimed to investigate the correlations between the levels of carbohydrate antigen 125 (CA125), human epididymis protein 4 (HE4), D-dimer (DDI), and fibrinogen degradation product (FDP) in patients with type II epithelial ovarian ...
Known for Ovarian Cancer | He4 Ca125 | Antigen Carcinoma | Protein 2
KOL-Index: 7522 . Blepharophimosis-ptosis-epicanthus inversus syndrome (BPES) is an autosomal dominant syndrome of eyelid malformations with (type I) or without (type II) associated premature ovarian failure. Multiple mutations in the exon and the putative core promoter region of FOXL2 gene encoding a putative forkhead transcription factor have been linked to this disease. To examine whether FOXL2 gene ...
Known for Foxl2 Gene | Epicanthus Inversus | Polyalanine Tract | Forkhead Transcription
KOL-Index: 7371 . BACKGROUND: MicroRNAs (miRNAs) play important roles in many important cellular processes and deregulation of miRNAs is linked to many human diseases including cancer. Although miR-424 has been demonstrated to inhibit progression of hepatocellular carcinoma (HCC), its expression level in serum samples and the potential clinical values remain unknown. MATERIALS AND METHODS: The expression ...
Known for Hepatocellular Carcinoma | Serum Mir424 | Hcc Patients | Biomarkers Tumor
KOL-Index: 7230 . BackgroundMidazolam has some potential in pain control of patients undergoing knee arthroscopy. However, the results remain controversial. We conduct a systematic review and meta-analysis to explore the effect of midazolam on pain control after knee arthroscopy.MethodsPubMed, EMbase, Web of science, EBSCO, and Cochrane library databases are systematically searched. Randomized controlled ...
Known for Knee Arthroscopy | Pain Control | Std Md | Analgesic Consumption
KOL-Index: 7220 . Extubation failure is a complex and ongoing problem in the intensive care unit (ICU). It refers to the patients who require re-intubation after extubation (namely disconnection from mechanical ventilation). In these patients, extubation failure leads to severe risks associated with re-intubation and is associated with increased mortalities, longer stay in ICU and also higher health care ...
Known for Extubation Failure | Gradient Boosting | Intensive Unit | Mechanical Ventilation
KOL-Index: 7124 . Background: Immune checkpoint inhibitors (ICIs) combined with chemotherapy have been applied as a first-line treatment for lung cancer, but consistent beneficial results have not been documented. Therefore, our meta-analysis aimed to evaluate the effectiveness and safety of combination therapy to promote its application. Methods: We searched electronic databases for studies that estimated ...
Known for Lung Cancer | Firstline Treatment | L1 Inhibitors | Combined Chemotherapy
KOL-Index: 7064 . Peritoneal fibrosis is a common complication of long-term peritoneal dialysis, and contributes to encapsulating peritoneal sclerosis and eventually peritoneal ultrafiltration failure, which restricts the wide application of peritoneal dialysis. Therefore, the prevention and treatment of peritoneal fibrosis is important to maintain peritoneal membrane integrity and prolong peritoneal ...
Known for Peritoneal Fibrosis | Body Fluids | Dialysis Patients | Common Complication
KOL-Index: 7009 . The versatile benefit effects of flavonoids lead some nutritionists to believe that they are micronutrients. However, excess intake of flavonoids may cause side effects. In this paper, the effects produced by a higher intake of rutin and baicalin on antioxidant status as well as trace minerals such as iron, copper and zinc in rat tissues were studied. When rats were fed a rutin or baicalin ...
Known for Rats Rutin | Lipid Peroxidation | Catalase Activity | Antioxidant Status

Key People For Extubation Failure

Top KOLs in the world
#1
Scott K Epstein
mechanical ventilation extubation failure arm elevation
#2
Andrés Esteban
mechanical ventilation septic shock respiratory distress
#3
Laurent Jean Brochard
mechanical ventilation respiratory distress lung injury
#4
Ronald L Ciubotaru
hospitalized patients mechanical ventilation failed extubation
#5
Inmaculada Alía
mechanical ventilation spontaneous breathing accidental removal
#6
Antonio R Anzueto
mechanical ventilation chronic obstructive copd exacerbations

Department of Gynecology, Obstetrics and Gynecology Hospital, Fudan University, No. 419, Fangxie Road, 200011, Shanghai, People’s Republic of China | College of Computer Science and Software, Shenzhen University, 47890 Shenzhen, Guangdong, China, 518