Philip Hart: Influence Statistics

Philip Hart

Philip Hart

SLAC National Accelerator Lab. (United States) | GE Research, Niskayuna, New York, USA | Ohio State University Comprehensive Cancer Center – James; College of Medicine, The ...

Philip Hart: Expert Impact

Concepts for which Philip Hart has direct influence: Structure determination , Ray lasers , Xray lasers , Coliphage pr772 , Free electron laser , Ray diffraction , Free electron .

Philip Hart: KOL impact

Concepts related to the work of other authors for which for which Philip Hart has influence: Radiation damage , Serial crystallography , Ray free , European xfel , Structure determination , Structural biology , Electron laser .

KOL Resume for Philip Hart

Year
2021

SLAC National Accelerator Lab. (United States)

2020

GE Research, Niskayuna, New York, USA

Ohio State University Comprehensive Cancer Center – James; College of Medicine, The Ohio State University Wexner Medical Center

2019

Linac Coherent Light Source, SLAC National Accelerator Laboratory, Menlo Park, CA94025, USA

2018

SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, 94025, California, CA, USA

2017

SLAC National Accelerator Laboratory, 2575 Sand Hill Road, 94025, Menlo Park, California, USA

2016

The Ohio State University Wexner Medical Center, Columbus, OH, USA

2014

Dept. of Electrical and Computer Engineering UW-Madison Madison, USA

2012

Linac Coherent Light Source, SLAC National Accelerator Laboratory, Menlo Park, CA 94025;

Particle Physics and Astrophysics, SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, CA 94025, USA.

Prominent publications by Philip Hart

KOL-Index: 5653 . The ultrabright femtosecond X-ray pulses provided by X-ray free-electron lasers open capabilities for studying the structure and dynamics of a wide variety of systems beyond what is possible with synchrotron sources. Recently, this "probe-before-destroy" approach has been demonstrated for atomic structure determination by serial X-ray diffraction of microcrystals. There has been the ...
Known for Ray Emission | Xes Spectra | Room Temperature | Oxidation States
KOL-Index: 4362 . Structure determination of proteins and other macromolecules has historically required the growth of high-quality crystals sufficiently large to diffract x-rays efficiently while withstanding radiation damage. We applied serial femtosecond crystallography (SFX) using an x-ray free-electron laser (XFEL) to obtain high-resolution structural information from microcrystals (less than 1 ...
Known for Structure Determination | Serial Femtosecond | Resolution Protein | Synchrotron Data
KOL-Index: 3770 . Single-particle diffraction from X-ray Free Electron Lasers offers the potential for molecular structure determination without the need for crystallization. In an effort to further develop the technique, we present a dataset of coherent soft X-ray diffraction images of Coliphage PR772 virus, collected at the Atomic Molecular Optics (AMO) beamline with pnCCD detectors in the LAMP instrument ...
Known for Ray Diffraction | Coliphage Pr772 | Light Source | Reconstruction Algorithms
KOL-Index: 3486 . BACKGROUND AND AIMS: Pancreatic ductal adenocarcinoma is an aggressive disease most often diagnosed after local progression or metastatic dissemination, precluding resection and resulting in a high mortality rate. For individuals with elevated personal risk of the development of pancreatic cancer, EUS is a frequently used advanced imaging and diagnostic modality. However, variability in ...
Known for Consensus Statement | Risk Individuals | Pancreatic Cancer | Early Detection
KOL-Index: 3045 . X-ray magnetic circular dichroism spectroscopy using an X-ray free electron laser is demonstrated with spectra over the Fe L(3,2)-edges. The high brightness of the X-ray free electron laser combined with high accuracy detection of incident and transmitted X-rays enables ultrafast X-ray magnetic circular dichroism studies of unprecedented sensitivity. This new capability is applied to a ...
Known for Ray Magnetic | Circular Dichroism | Free Electron | Absorption Spectroscopy
KOL-Index: 2575 . The dynamics of liquid water feature a variety of time scales, ranging from extremely fast ballistic-like thermal motion, to slower molecular diffusion and hydrogen-bond rearrangements. Here, we utilize coherent X-ray pulses to investigate the sub-100 fs equilibrium dynamics of water from ambient conditions down to supercooled temperatures. This novel approach utilizes the inherent ...
Known for Liquid Water | Speckle Contrast | Molecular Dynamics Simulations | Time Scales
KOL-Index: 1948 . A reduced-order model is used to derive a candidate energy function for a system that includes an infinite bus connected with a single frequency-droop-controlled inverter (a ‘MicroSource’) whose frequency command is actuated according to its low-pass-filtered active power measurement. The analysis of the large-signal stability of such a system is important in understanding the duration ...
Known for Controlled Inverter | Infinite Bus | Energy Function | Control Parameters
KOL-Index: 1648 . The possibility of imaging single proteins constitutes an exciting challenge for x-ray lasers. Despite encouraging results on large particles, imaging small particles has proven to be difficult for two reasons: not quite high enough pulse intensity from currently available x-ray lasers and, as we demonstrate here, contamination of the aerosolized molecules by nonvolatile contaminants in ...
Known for Ray Lasers | Single Proteins | Particle Imaging | Sample Delivery
KOL-Index: 1075 . The Macromolecular Femtosecond Crystallography (MFX) instrument at the Linac Coherent Light Source (LCLS) is the seventh and newest instrument at the world's first hard X-ray free-electron laser. It was designed with a primary focus on structural biology, employing the ultrafast pulses of X-rays from LCLS at atmospheric conditions to overcome radiation damage limitations in biological ...
Known for Femtosecond Crystallography | Light Source | Structural Biology | Time Resolved
KOL-Index: 503 . The possibility of imaging single proteins constitutes an exciting challenge for X-ray lasers. Despite encouraging results on large particles, imaging small particles has proven to be difficult for two reasons: not quite high enough pulse intensity from currently available X-ray lasers and, as we demonstrate here, contamination of the aerosolised molecules by non-volatile contaminants in ...
Known for Imaging Single | Structure Determination | Free Sample
KOL-Index: 173 . The day-to-day operation of modern power systems is highly reliant on prompt and adequate situational-awareness. This can be achieved via various system monitoring functions such as anomaly detection, in which static thresholds are commonly utilized to distinguish the normal and the abnormal system states. However, a predetermined static threshold usually lacks the flexibility to adapt to ...
Known for Chebyshev Inequality

Key People For Structure Determination

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SLAC National Accelerator Lab. (United States) | GE Research, Niskayuna, New York, USA | Ohio State University Comprehensive Cancer Center – James; College of Medicine, The Ohio State University Wexner Medical Center | Linac Coherent Light Source, SL