• KOL
    • Hepatocellular Carcinoma
    • Hong Zhao
    • Hong Zhao: Influence Statistics

      Hong Zhao

      Hong Zhao

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      Department of Hepatobiliary Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union ...

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      Hong Zhao:Expert Impact

      Concepts for whichHong Zhaohas direct influence:Hepatocellular carcinoma,Simultaneous resection,Liver metastases,Early recurrence,Radical resection,Colorectal liver metastases,Lymph node metastasis,Colorectal cancer.

      Hong Zhao:KOL impact

      Concepts related to the work of other authors for whichfor which Hong Zhao has influence:Hepatocellular carcinoma,Liver cancer,Idiopathic scoliosis,Neoadjuvant chemotherapy,Surgical treatment,Blood loss,Spinal fusion.

      KOL Resume for Hong Zhao

      Year
      2022

      Department of Hepatobiliary Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.

      Key Laboratory of Gene Editing Screening and R&D of Digestive System Tumor Drugs, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

      2021

      Key Laboratory of Gene Editing Screening and R & D of Digestive System Tumor Drugs, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

      2020

      Department of Hepatobiliary Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

      Key Laboratory of Gene Editing Screening and R&D of Digestive System Tumor Drugs, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021 China

      2019

      Department of Orthopaedic Surgery, Peking Union Medical College Hospital, Beijing 100730, China.

      2018

      Department of Orthopedics, Peking Union Medical College Hospital, Beijing, P.R. China

      2017

      Department of Orthorpaedic Surgery, Peking Union Medical College Hospital, Beijing 100730, P.R. China

      2016

      Department of Abdominal Surgical Oncology, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China

      2015

      Department of Abdominal Surgery, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

      2014

      Hong Mu, Fang Liu, Yu-Lin Sun, Xiao-Hang Zhao, State Key Laboratory of Molecular Oncology, Cancer Institute Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

      Department of Orthopaedic Surgery, Peking Union Medical College Hospital, No. 1 Shuai Fu Yuan, Wang Fu Jing Street, 100730 Beijing, China

      2013

      Department of Abdominal Surgical Oncology, Cancer Hospital, Chinese Academy of Medical Sciences, 17 Panjiayuan Nanli, Chaoyang District, Beijing 100021, PR China

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      Sample of concepts for which Hong Zhao is among the top experts in the world.
      Concept World rank
      0000 length #1
      aav5wif1 #1
      tranexamic acid drain #1
      thrombocytopenia increased duration #1
      active prevention incidence #1
      liver metastases pnet #1
      gossypol injection #1
      drain 2 #1
      drain blood loss #1
      980 ± 244 #1
      surgery thrombocytopenia #1
      gossypol promotes #1
      ovariectomyinduced osteoporosis osteoporosis #1
      wif1 ovariectomy #1
      0000 txa #1
      txa ivtxa #1
      spinal tumors complications #1
      combined topical txa #1
      hospitalization total drainage #1
      shorter gelfoam #1
      txa gelfoam #1
      gelfoam control #1
      drain combined #1
      operation level groups #1
      gossypol human osteoporosis #1
      retrogradely drain #1
      drain degenerative #1
      survival time cox #1
      level wif1 #1
      cell proliferation wif1 #1
      surgeryrelated parameters segments #1
      txa drain #1
      follow duration patients #1
      total drainage txa #1
      segments bleeding volume #1
      ivtxa txa #1
      topical injection txa #1
      nomogram preoperative creatinine #2
      tissue afp #2
      lncrnas colorectal cscs #2
      correlation rhbdd1 #2
      correlation rhbdd1 expression #2
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      Prominent publications by Hong Zhao

      KOL-Index: 18916

      Background40–50% of colorectal cancer (CRC) patients develop metastatic disease; the presence of metastasis hinders the effective treatment of cancer through surgery, chemotherapy and radiotherapy, which makes 5-year survival rate extremely low; therefore, studying CRC metastasis is crucial for disease therapy. In the present study, we investigated the role of rhomboid domain containing 1 (RHBDD1) in tumor metastasis of CRC.MethodsThe expression of RHBDD1 was analyzed in 539 colorectal ...

      Known for Signaling Pathway | Crc Cells | Downstream Target | Cancer Metastasis | Western Blot
      KOL-Index: 14020

      STUDY DESIGN: An analysis of computed tomography (CT) images of patients with adolescent thoracic idiopathic scoliosis for posterior pedicle screw placement.

      OBJECTIVE: To evaluate the relative position of the aorta to the spine by the axial CT scans in patients with right thoracic idiopathic scoliosis, and to discuss the safe trajectory and screw length for posterior pedicle screw placement.

      SUMMARY OF BACKGROUND DATA: Posterior pedicle screw instrumentation and fusion are widely used ...

      Known for Screw Placement | Idiopathic Scoliosis | Aorta Relative | Thoracic Spine | Angle Α
      KOL-Index: 11834

      STUDY DESIGN: A prospective study.

      OBJECTIVE: Comparison study of radiologic and clinical outcomes, efficiency, and cost between anterior spinal fusion (ASF) and posterior spine fusion (PSF) in surgical treatment of moderate lumbar/thoracolumbar adolescent idiopathic scoliosis (AIS).

      SUMMARY OF BACKGROUND DATA: ASF and PSF indicated for lumbar and thoracolumbar adolescent idiopathic scoliosis surgical treatment have respective advantages and disadvantages. However, up until today, a ...

      Known for Spinal Fusion | Asf Psf | Adolescent Idiopathic Scoliosis | Versus Posterior | Thoracolumbar Lumbar
      KOL-Index: 11059

      APOBEC3s are a family of cytidine deaminases involved in innate cellular immunity against virus including hepatitis B virus (HBV). A germline deletion across APOBEC3A and APOBEC3B (A3B) genes results in complete removal of the A3B coding region and destroys A3B expression. To determine whether this deletion affects susceptibility to HBV infection and HBV-related hepatocellular carcinoma (HCC), A3B genotypes were analyzed in 1124 individuals with HCC, 510 individuals with persistent HBV ...

      Known for Hepatocellular Carcinoma | Hbv Infection | Gene Deletion | Hepatitis Virus | Hcc Cells
      KOL-Index: 9967

      STUDY DESIGN: Retrospective review.

      OBJECTIVE: To evaluate the efficacy of multimodal intraoperative neuromonitoring for predicting iatrogenic neurological injury during surgical correction of a spine deformity and evaluate the potential risk factors for neurological monitoring changes.

      SUMMARY OF BACKGROUND DATA: Single modal intraoperative neuromonitoring is insufficient to predict neurological injury during surgical correction of spine deformity. Multimodal monitoring can provide more ...

      Known for Intraoperative Monitoring | Spine Deformity | Surgical Correction | Neurological Injury | Motor Evoked Potentials
      KOL-Index: 9865

      The receptor-interacting protein kinase 1 (RIPK1) is an essential signaling molecule in pathways for cell survival, apoptosis, and necroptosis. We report here that RIPK1 is upregulated in human colorectal cancer and promotes cell proliferation when overexpressed in a colon cancer cell line. RIPK1 interacts with mitochondrial Ca2+ uniporter (MCU) to promote proliferation by increasing mitochondrial Ca2+ uptake and energy metabolism. The ubiquitination site of RIPK1 (RIPK1-K377) was ...

      Known for Mitochondrial Ca2 | Cell Proliferation | Colorectal Cancer | Inbred Balb Mice | Energy Metabolism
      KOL-Index: 9675

      Assessing the prognosis of patients with hepatocellular carcinoma (HCC) by the number and size of tumors is sometimes difficult. The main purpose of the study was to evaluate the prognostic value of total tumor volume (TTV), which combines the two factors, in patients with HCC who underwent liver resection. We retrospectively reviewed 521 HCC patients from January 2001 to December 2008 in our center. Patients were categorized using the tertiles of TTV. The prognostic value of TTV was ...

      Known for Hepatocellular Carcinoma | Liver Resection | Total Tumor Volume | Patients Hcc | Prognostic Ttv
      KOL-Index: 9580

      BACKGROUND: Although measures to reduce and treat degenerative changes after fusion are discussed, these are still controversial.

      METHODS: A retrospective study was conducted on a consecutive series of 3,799 patients who underwent posterior lumbar fusion for degenerative lumbar disease between January 1999 and January 2009. A total of 28 patients with symptomatic adjacent segment degeneration surgery were identified. Another group of 56 matched patients with degenerative lumbar disease ...

      Known for Adjacent Segment | Lumbar Fusion | Disc Degeneration | Predictive Factors | Retrospective Studies
      KOL-Index: 9520

      STUDY DESIGN: A retrospective study of 1162 consecutive patients who underwent spinal deformity surgical procedures at our spine center from January 2010 to December 2013.

      OBJECTIVE: To develop and evaluate a protocol of intraoperative motor evoked potential (MEP) monitoring with the warning criteria we had established on the basis of our clinical experiences and the review of previous literature.

      SUMMARY OF BACKGROUND DATA: Though MEPs monitoring have become widely used in spinal ...

      Known for Intraoperative Motor | Spinal Deformity | Mep Monitoring | Positive Predictive | Evoked Potential
      KOL-Index: 9479

      Tumor-initiating cell (TIC) is a subpopulation of cells in tumors that are responsible for tumor initiation and progression. Recent studies indicate that hepatocellular carcinoma-initiating cells (HCICs) confer the high malignancy, recurrence and multi-drug resistance in hepatocellular carcinoma (HCC). In this study, we found that Icaritin, a prenylflavonoid derivative from Epimedium Genus, inhibited malignant growth of HCICs. Icaritin decreased the proportion of EpCAM-positive (a HCICs ...

      Known for Hepatocellular Carcinoma | Malignant Growth | Janus Kinase | Hcc Icaritin | Tumor Cells
      KOL-Index: 9477

      STUDY DESIGN: A case-control association study was performed to investigate the relationship between ladybird homeobox (LBX1) and adolescent idiopathic scoliosis (AIS) in northern Chinese Han population.

      OBJECTIVE: To explore the prevalence and functional importance of LBX1 polymorphisms in patients with AIS within the northern Chinese Han population.

      SUMMARY OF BACKGROUND DATA: AIS is the most common subtype of idiopathic scoliosis. Genetic factors such as LBX1 polymorphisms have been ...

      Known for Northern Chinese | Lbx1 Ais | Adolescent Idiopathic | Risk Allele | Genetic Factors
      KOL-Index: 8984

      OBJECTIVE: To analyze the factors affecting lymph node metastasis and the prognosis of rectal neuroendocrine tumors after surgical treatment.

      METHODS: A retrospective analysis was conducted using the clinical data from 156 cases of rectal neuroendocrine tumors during the period of January 1999 to December 2013. The Kaplan-Meier method was used to calculate the survival time, Cox regression analysis was performed for statistical analysis of clinicopathological factors that may be ...

      Known for Lymph Node Metastasis | Rectal Neuroendocrine Tumors | Depth Invasion | Retrospective Studies | Tumor Size
      KOL-Index: 8889

      Osteosarcoma is a prevalent type of cancer and has a high metastatic ability, particularly for metastasis to the lungs. Effective treatment strategies have improved, however, the detailed molecular mechanism underlying the onset of this malignancy remains to be fully elucidated. The current study investigated the role of the tripartite motif (TRIM) family protein TRIM59 in osteosarcoma growth and metastasis. It was identified that TRIM59 was overexpressed in clinical osteosarcoma tissues ...

      Known for Cell Proliferation | Neoplastic Humans | Overexpression Trim59 | Tripartite Motif | Proteins Membrane Proteins
      KOL-Index: 8835

      Hepatocellular carcinoma (HCC) is one of the most common digestive system malignant tumors. Due to the resistance to radiotherapy, the prognosis in patients with HCC is poor. Based on previous studies and online tools prediction, we hypothesized that miR-92b, which was reported to promote HCC cell proliferation, might bind to p57kip2, a well-known tumor suppressor, to modulate the radioresistance of HCC to ionizing radiation (IR) -based radiotherapy. In the present study, a higher ...

      Known for Hepatocellular Carcinoma | Ionizing Radiation | P57kip2 Expression | Hcc Cells | Kinase Inhibitor
      KOL-Index: 8714

      OBJECTIVE: The aim of the present study was to investigate whether an innovative way of administering tranexamic acid (TXA), that is, injecting it retrogradely through the drain and clamping it for 1 h, can reduce postoperative bleeding after degenerative lumbar scoliosis surgery.

      METHODS: Sixty degenerative lumbar scoliosis patients who underwent posterior lumbar decompression with fusion of three or more levels were retrospectively enrolled and categorized into three groups (TXA, ...

      Known for Tranexamic Acid | Blood Loss | Txa Drain | Lumbar Scoliosis | Postoperative Complications

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      Department of Hepatobiliary Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China. | Department of Hepatobiliary Surg

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