• KOLs
  • Cystic Fibrosis
  • Leslie Dan Faculty Of Pharmacy Taddio, University

Leslie Dan Faculty of Pharmacy Taddio, University : Influence Statistics

Leslie Dan Faculty of Pharmacy: Expert Impact

Concepts for which Leslie Dan Faculty of Pharmacy has direct influence: Cystic fibrosis .

Leslie Dan Faculty of Pharmacy: KOL impact

Concepts related to the work of other authors for which for which Leslie Dan Faculty of Pharmacy has influence: Cystic fibrosis , Gene expression , Stem cells , Multiple sclerosis , Breast cancer , Oxidative stress , Pediatric patients .

KOL Resume for Leslie Dan Faculty of Pharmacy Taddio, University


Prominent publications by Leslie Dan Faculty of Pharmacy Taddio, University

KOL-Index: 93354 . Canada has among the highest rates of childhood-onset IBD in the world. Over 7000 children and youth under 18 years old are living with IBD in Canada, and 600 to 650 children under 16 years old are diagnosed annually. While the peak age of onset of IBD is highest in the second and third decades of life, over the past two decades incidence has risen most rapidly in children under 5 years ...
Known for Children Ibd | Inflammatory Bowel Disease | Pediatric Adult | Health Providers
KOL-Index: 32592 . BACKGROUND: Multiple-micronutrient (MMN) deficiencies often coexist among women of reproductive age in low- to middle-income countries. They are exacerbated in pregnancy due to the increased demands, leading to potentially adverse effects on the mother and developing fetus. Though supplementation with MMNs has been recommended earlier because of the evidence of impact on pregnancy ...
Known for Iron Folic Acid | Women Pregnancy | Average 95 | Mmn Supplements
KOL-Index: 28486 . BACKGROUND: With the development of newer antifungal agents with activity against both yeasts and filamentous fungi, there is an increased need to develop and standardize in vitro assays that will evaluate the activity of antimycotics against filamentous fungi. In vitro analysis of antifungal activity of these agents would also allow for the comparison between different antimycotics, which ...
Known for Terbinafine Itraconazole | Antifungal Activity | Vitro Susceptibility | Microg Ml1
KOL-Index: 28447 . BACKGROUND: Multiple-micronutrient (MMN) deficiencies often coexist among women of reproductive age in low- and middle-income countries. They are exacerbated in pregnancy due to the increased demands of the developing fetus, leading to potentially adverse effects on the mother and baby. A consensus is yet to be reached regarding the replacement of iron and folic acid supplementation with ...
Known for Mmn Supplementation | Women Pregnancy | Average 95 | Iron Acid Supplements
KOL-Index: 28380 . BACKGROUND: Lumacaftor and ivacaftor combination treatment showed efficacy in patients aged 12 years or older with cystic fibrosis homozygous for F508del-cystic fibrosis transmembrane conductance regulator (CFTR) in placebo-controlled studies and patients aged 6-11 years with cystic fibrosis homozygous for F508del-CFTR in an open-label study. We report efficacy and safety of lumacaftor and ...
Known for Cystic Fibrosis | Lumacaftor Ivacaftor | 11 Years | Lci2·5 Treatment
KOL-Index: 27662 . BACKGROUND: Immunization is the most common cause of iatrogenic pain in childhood. Despite the availability of various analgesics to manage vaccine injection pain, they have not been incorporated into clinical practice. To date, no systematic review has been published on the effectiveness of pharmacologic and combined interventions for reducing injection pain. OBJECTIVES: The objectives of ...
Known for Injection Pain | Smd 95 | Combined Interventions | Childhood Immunizations
KOL-Index: 27413 . BACKGROUND: The role of enteral nutrition in Crohn's disease is controversial. Increasing research on the mechanisms by which nutritional therapy improves the clinical well being of patients with Crohn's disease has led to novel formula design and trials comparing two different forms of enteral nutrition. This systematic review aims to provide an update on the existing efficacy data for ...
Known for Enteral Nutrition | Crohns Disease | Subgroup Analyses | Elemental Diet
KOL-Index: 26764 . BACKGROUND: Peripheral nerve block (infiltration of local anaesthetic around a nerve) is used for anaesthesia or analgesia. A limitation to its use for postoperative analgesia is that the analgesic effect lasts only a few hours, after which moderate to severe pain at the surgical site may result in the need for alternative analgesic therapy. Several adjuvants have been used to prolong the ...
Known for Peripheral Nerve Block | Md 95 | Intravenous Dexamethasone | Participants Studies
KOL-Index: 26677 . BACKGROUND: Current guidelines recommend performance of oesophago-gastro-duodenoscopy at the time of diagnosis of hepatic cirrhosis to screen for oesophageal varices. These guidelines require people to undergo an unpleasant invasive procedure repeatedly with its attendant risks, despite the fact that half of the people do not have identifiable oesophageal varices 10 years after the initial ...
Known for Oesophageal Varices | Capsule Endoscopy | Chronic Liver Disease | Portal Vein Thrombosis
KOL-Index: 26332 . OBJECTIVE: Sudden hearing loss is a frightening symptom that often prompts an urgent or emergent visit to a health care provider. It is frequently but not universally accompanied by tinnitus and/or vertigo. Sudden sensorineural hearing loss affects 5 to 27 per 100,000 people annually, with about 66,000 new cases per year in the United States. This guideline update provides evidence-based ...
Known for Hearing Loss | Sudden Sensorineural | Symptom Onset | Initial Treatment
KOL-Index: 26187 . BACKGROUND: Chest physiotherapy is widely prescribed to assist the clearance of airway secretions in people with cystic fibrosis. Oscillating devices generate intra- or extra-thoracic oscillations orally or external to the chest wall. Internally they create variable resistances within the airways, generating controlled oscillating positive pressure which mobilises mucus. Extra-thoracic ...
Known for Cystic Fibrosis | Oscillating Devices | Airway Clearance | Frequency Exacerbations
KOL-Index: 26128 . BACKGROUND: Corticosteroids are effective for induction, but not maintenance of remission in Crohn's disease. Significant concerns exist regarding the risk for adverse events, particularly when corticosteroids are used for long treatment courses. Budesonide is a glucocorticoid with limited systemic bioavailability due to extensive first-pass hepatic metabolism and is effective for ...
Known for Remission Budesonide | Placebo Patients 95 | Sparse Data | Evidence Outcome
KOL-Index: 24983 . BACKGROUND: Febrile seizures occurring in a child older than one month during an episode of fever affect 2% to 4% of children in Great Britain and the United States and recur in 30%. Rapid-acting antiepileptics and antipyretics given during subsequent fever episodes have been used to avoid the adverse effects of continuous antiepileptic drugs. OBJECTIVES: To evaluate the effectiveness and ...
Known for Febrile Seizures | 12 Months | Placebo Treatment | Prophylactic Drug Management
KOL-Index: 24915 . BACKGROUND: Antibiotic therapy for acute pulmonary exacerbations in people with cystic fibrosis is usually chosen based on the results of antimicrobial susceptibility testing of individual drugs. Combination antimicrobial susceptibility testing assesses the efficacy of drug combinations including two or three antibiotics in vitro and can often demonstrate antimicrobial efficacy against ...
Known for Cystic Fibrosis | Pseudomonas Aeruginosa | Chronic Infection | Acute Exacerbations
KOL-Index: 24907 . BACKGROUND: Endoscopy has traditionally been taught with novices practicing on real patients under the supervision of experienced endoscopists. Recently, the growing awareness of the need for patient safety has brought simulation training to the forefront. Simulation training can provide trainees with the chance to practice their skills in a learner-centred, risk-free environment. It is ...
Known for Simulation Training | Virtual Reality | Gastrointestinal Endoscopy | Composite Score

Key People For Cystic Fibrosis

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