• Sex Ratio
    • Jiali Cai
    • Jiali Cai: Influence Statistics

      Jiali Cai

      Jiali Cai

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      Xiamen University Affiliated Chenggong Hospital | The Affiliated Chenggong Hospital of Xiamen University | School of Medicine, Xiamen University, Xiamen, China | The ...

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      Jiali Cai:Expert Impact

      Concepts for whichJiali Caihas direct influence:Sex ratio,Sebastiscus marmoratus,Embryo transfer,Polychlorinated biphenyls,Ectopic pregnancy,Vitro fertilization,Live birth,Neonatal birthweight.

      Jiali Cai:KOL impact

      Concepts related to the work of other authors for whichfor which Jiali Cai has influence:Polychlorinated biphenyls,Organotin compounds,Live birth,Pc12 cells,Perinatal outcomes,Gastrodia elata,Embryo transfer.

      KOL Resume for Jiali Cai


      Xiamen University Affiliated Chenggong Hospital


      The Affiliated Chenggong Hospital of Xiamen University


      School of Medicine, Xiamen University, Xiamen, Fujian, China


      Medical College, Xiamen University, Xiamen, Fujian, China


      The Affiliated Chenggong Hospital, Xiamen University, 361002, Xiamen, Fujian, China


      Reproductive Medicine Centre, The Affiliated Chenggong Hospital of Xiamen University, 361002, Xiamen, Fujian, China


      Reproductive Medicine Center, The Affiliated Chenggong Hospital of Xiamen University, Xiamen, Fujian, 361002, China


      Reproductive Medicine Center, The Affiliated Chenggong Hospital of Xiamen University Xiamen, Fujian 361002, China.


      Department of Clinical College in No. 174 Hospital of PLA, Xiamen 361003, China


      State Key Laboratory of Cellular Stress Biology, School of Life Sciences and


      Key Laboratory of Ministry of Education for Subtropical Wetland Ecosystem Research, Xiamen University, Xiamen, PR China


      Key Laboratory of the Ministry of Education for Coast and Wetland Ecosystems, School of Life Sciences, Xiamen University, Xiamen 361005, China


      Key Laboratory of the Ministry of Education for Coast and Wetland Ecosystems.


      Key Laboratory of the Ministry of Education for Cell Biology and Tumor Cell Engineering, School of Life Sciences, Xiamen University, Xiamen City 361005, PR China


      School of Life Sciences, Xiamen University, Xiamen, China

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      Sample of concepts for which Jiali Cai is among the top experts in the world.
      Concept World rank
      prosaposin fertilization #2
      fragmentation cleavage stage #2
      gee prosaposin #2
      cleavage stage association #2
      association embryo parameters #2
      dose oocyte yield #2
      prosaposin concentrations #2
      3 fragmentation symmetry #2
      prosaposin fertilization rate #2
      symmetry blastomere #2
      4226 singletons #2
      parameters prosaposin #2
      prosaposin seminal #2
      female basal fsh #2
      blastocyst transfer fragmentation #2
      day 3 fragmentation #2
      blastocyst morphology birthweight #2
      birthweight blastocyst #2
      blastocyst morphology fragmentation #2
      early cleavage symmetry #2
      fragmentation birthweight #2
      prosaposin concentration #2
      association seminal prosaposin #2
      suggested prosaposin #2
      blastomere blastocyst morphology #2
      seminal prosaposin #2
      stage birthweight #2
      birthweight morphological #2
      epydidymal spermatozoa #3
      factors saposins #3
      psap abundance sperm #3
      psap pcb exposure #3
      suggested seminal #3
      detectable pcb exposure #3
      psap expression sperm #3
      depressed psap level #3
      abundance psap #3
      psap sperm #3
      psap abundance #3
      semen psap #3
      prosaposin psap expression #3
      psap decreased #3
      psap reduction aroclor #3
      atrp53 mediated apoptosis #4
      thirtytwo micromolar #4
      fet affect #4
      so2 live #4
      concentrationdependent manner tbt #4
      incidence lga newborns #4
      so2 vitro humans #4
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      Prominent publications by Jiali Cai

      KOL-Index: 11453

      Although the etiology of PD remains unclear, increasing evidence has shown that oxidative stress plays an important role in its pathogenesis and that of other neurodegenerative disorders. The phenolic glucoside gastrodin, a main constituent of a Chinese herbal medicine Gastrodia elata (GE) Blume, has been known to display antioxidant activity. The present study aimed to investigate the protective effects of gastrodin on 1-methyl-4-phenylpyridinium (MPP(+))-induced oxidative cytotoxicity ...

      Known for Oxidative Stress | Nrf2 Pathway | P38 Mapk | Protective Gastrodin | Ho1 Expression
      KOL-Index: 10596

      OBJECTIVE: To evaluate the effects of low body mass index (BMI) on in vitro fertilization (IVF) outcomes in fresh transfer cycles.

      DESIGN: Retrospective cohort study.

      SETTING: University-affiliated hospital.

      PATIENT(S): A total of 4,798 cycles with conventional stimulation and fresh transfer in a single IVF center during the period 2013-2014. Low BMI (<18.5 kg/m2) was defined according to World Health Organization guidelines, and cycles within a normal weight range (18.5-24.9 kg/m2) were ...

      Known for Live Birth | Fresh Transfer | Low Bmi | Fertilization Cycles | Ivf Outcomes
      KOL-Index: 9025

      STUDY QUESTION: Does outdoor air pollution differentially affect the outcomes of frozen-thawed embryo transfer (FET) and fresh transfer in IVF treatment?

      SUMMARY ANSWER: Increased SO2 and O3 levels at the site of IVF unit were significantly associated with lower live birth rates following FET but did not affect the contemporary fresh transfer outcomes.

      WHAT IS KNOWN ALREADY: Ambient air pollution has been associated with human infertility and IVF outcomes. However, most of the studies ...

      Known for Embryo Transfer | Air Pollution | Ivf Outcomes | Vitro Humans | Live Birth
      KOL-Index: 8932

      Organotin compounds, such as tributyltin (TBT), that have been used as antifouling biocides can induce masculinization in female mollusks. However, few studies addressing the effects of TBT on fishes have been reported. The present study was conducted to investigate the effects of TBT at environmentally relevant concentrations (1, 10, and 100 ng/L) on testicular development in Sebastiscus marmoratus and to gain insight into its mechanism of action. After exposure for 48 d, the ...

      Known for Sebastiscus Marmoratus | Testicular Development | Tbt Exposure | Peroxisome Proliferator | Retinoid Receptors
      KOL-Index: 7756

      Tributyltin (TBT), widely used as an antifouling biocide, is the most abundant pesticide in coastal environments. Trimethyltin (TMT) is a potent neurotoxicant of a mechanism of action yet to be uncovered. The neurotoxicity of TBT and TMT on the brain of marine fish Sebastiscus marmoratus was investigated in this study. The results showed that TBT and TMT can modulate amino acid neurotransmitters and N-methyl-D-aspartate receptor (NMDAR) signaling pathway in the brain of marine fish in a ...

      Known for Sebastiscus Marmoratus | Signaling Pathway | Tributyltin Tbt | Marine Fish | Dosedependent Manner
      KOL-Index: 6627

      The testicular toxicity of polychlorinated biphenyls (PCBs) has been extensively studied. However, the detailed mechanism is still obscure. In the present study, male C57 mice were treated with different doses of Aroclor 1254 (a commercial PCB mixture) once every 3 days by oral gavage. After exposure to Aroclor 1254 for 50 days, the sperm count decreased in a dose-dependent manner. Cell proliferation and apoptosis are key processes regulating development of the testis, and alterations in ...

      Known for Estrogen Receptor | Testicular Toxicity | Doseresponse Relationship | Cell Proliferation | Dosedependent Manner
      KOL-Index: 6052

      OBJECTIVE: To investigate whether supraphysiological estradiol (E2 ) in controlled ovarian stimulation (COS) cycles affects the subsequent frozen-thawed embryo transfer (FET) in terms of the neonatal birthweight.

      DESIGN: Retrospective cohort study.

      SETTING: University affiliated hospital.

      POPULATION: In all, 2066 patients undergoing FET cycles that resulted in live singleton births between July 2011 and Dec 2016.


      METHODS: Multivariable linear regression and logistic ...

      Known for Ovarian Stimulation | Gestational Age | Fet Cycles | Neonatal Birthweight | Estradiol Level
      KOL-Index: 5779

      PurposeThe purpose of the study is to compare the newborns weight in singleton term birth following transfer of thawed blastocysts–frozen on either day 5 or day 6 after in vitro fertilization.MethodThe retrospective study included 1444 frozen–thawed blastocyst transfer (FBT) cycles resulting in live singleton births between Jan 2013 and Dec 2016. The main outcomes measured were absolute birth weight, z-score adjusted for gestational age and gender, and incidence of ...

      Known for Day 6 | Birth Weight | Gestational Age | Embryo Transfer | Vitro Fertilization
      KOL-Index: 5586

      Polychlorinated biphenyls (PCBs) are ubiquitous legacy persistent pollutants and epidemiological data showed that PCB burdens were associated with failed implantation in human. However, the mechanism how PCB exposure affects the embryo implantation is not clear. Using an in vitro model for human embryo implantation employing the human choriocarcinoma cell line JAR and the human endometrial cell line Ishikawa, we have shown that PCB mixture Aroclor 1254 at environmental-relevant ...

      Known for Endometrial Receptivity | Polychlorinated Biphenyls | Epithelial Mesenchymal | Embryo Implantation | Transition Emt
      KOL-Index: 5152

      Polychlorinated biphenyls (PCBs) exhibit a broad range of adverse biological effects, including reproductive toxicity. However, the mechanisms by which PCBs disrupt the epididymis remain obscure. We analyzed the gene expression profile in mice epididymis exposed to PCBs (Aroclor 1254) at doses comparable to human exposure using a cDNA microarray. Differentially expressed genes were involved in a variety of function categories and biological pathways, including GTP binding, nucleosome ...

      Known for Polychlorinated Biphenyls | Tight Junctions | Pcb Exposure | Bloodepididymis Barrier | Sperm Maturation
      KOL-Index: 5013

      PurposeThe purpose of this study is to investigate whether individual response of anti-Mullerian hormone (AMH) to gonadotropin-releasing hormone (GnRH) treatment is associated with difference in ovarian stimulation outcomes.MethodsThe retrospective study included 1058 non-polycystic ovary syndrome (PCOS) women undergoing long agonist protocol in a single in vitro fertilization unit from January 1, 2016, through December 31, 2016. Patients were grouped according to AMH changes from day 3 ...

      Known for Embryo Transfer | Hormone Amh | Gnrh Agonist | Vitro Fertilization | Gonadotropin Releasing
      KOL-Index: 4117

      In evaluating the cytotoxic effects and the mechanisms of the apoptotic and necrotic actions of trimethyltin chloride (TMT) on human hepatoma G2 (HepG2) cells, the present study focused on the involvement of antiproliferation, DNA damage, cell death, apoptosis-related proteins, and p53-dependent transcriptional activity. Twenty-four hour TMT treatments (4-64 microM) induced apoptosis and necrosis in HepG2 cells. Thirty-two micromolar and higher concentration significantly increases cell ...

      Known for Tumor Comet | Hepg2 Cells | Human Hepatoma | Trimethyltin Compounds | Dna Damage
      KOL-Index: 4019

      Trimethyltin (TMT) is a well-documented neurotoxicant that affects the function of central nervous system (CNS). In this study, we studied the neurotoxicity of TMT on the brain of marine fish Sebastiscus marmoratus. Our results showed that TMT acute exposure induced brain cell apoptosis in the telencephalon, optic tectum and cerebellum. In addition, we observed increased production of reactive oxygen species (ROS), nitric oxide (NO) and one asparate-specific cysteinyl protease named ...

      Known for Oxidative Stress | Cell Apoptosis | Reactive Oxygen Species | Tmt Exposure | Central Nervous
      KOL-Index: 3816

      Tributyltin (TBT) is a ubiquitous marine contaminant due to its extensive use as a biocide, fungicide and antifouling agent. However, the neurotoxic effect of TBT has not been extensively studied, especially in marine fish. This study was conducted to investigate the effects of TBT (10, 100 and 1000 ng/L) on the predatory behavior of Sebastiscus marmoratus and to look into the mechanism involved. The results showed that TBT exposure depressed predatory activity after 50 days exposure. ...

      Known for Sebastiscus Marmoratus | Tbt Exposure | Mrna Levels | Motor Activity | Water Pollutants
      KOL-Index: 3046

      OBJECTIVE: To evaluate the impact of air pollution on the sex ratio in singletons after IVF treatment and to evaluate the influence of the number of and the developmental stage of transferred embryos on the sex ratio.

      DESIGN: Retrospective cohort study.

      SETTING: University-affiliated IVF unit.

      PATIENT(S): A total of 7,004 singletons born after fresh transfer or frozen-thawed embryo transfer (FET) between January 2013 and December 2017.

      INTERVENTION(S): None.


      Known for Air Pollutants | Vitro Humans | Retrospective Cohort Study | Ivf Treatment | Embryo Transfer

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      Xiamen University Affiliated Chenggong Hospital | The Affiliated Chenggong Hospital of Xiamen University | School of Medicine, Xiamen University, Xiamen, China | The Affiliated Chenggong Hospital of Xiamen University, 361002, Xiamen, Fujian, China |

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