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  • Section Of Pediatric Nephrology, Children's Mercy

Section of Pediatric Nephrology, Children's Mercy : Influence Statistics

Section of Pediatric Nephrology Children's: Expert Impact

Concepts for which Section of Pediatric Nephrology Children's has direct influence: Pediatric patients , United states , Chronic kidney disease .

Section of Pediatric Nephrology Children's: KOL impact

Concepts related to the work of other authors for which for which Section of Pediatric Nephrology Children's has influence: Pediatric patients , Preterm infants , Type 1 diabetes , United states , Newborn infant , Chronic kidney disease , Physical activity .

KOL Resume for Section of Pediatric Nephrology, Children's Mercy


Prominent publications by Section of Pediatric Nephrology, Children's Mercy

KOL-Index: 31468 . BACKGROUND: Benign prostatic hyperplasia (BPH) refers to non-malignant enlargement of the prostate gland that may cause bothersome lower urinary tract symptoms (LUTS). Alpha-blockers (ABs) and 5-alpha reductase inhibitors (5-ARIs) are the mainstay of medical treatment. Recently, phosphodiesterase inhibitors (PDEIs) that so far have been used mainly to treat erectile dysfunction were ...
Known for Benign Prostatic Hyperplasia | Lower Urinary | Phosphodiesterase Inhibitors | 12 Weeks Pdei
KOL-Index: 21819 . Background: Inhaled corticosteroids (ICSs) are the preferred maintenance therapy for adults and children with mild, moderate and severe persistent asthma, with the addition of a long-acting β2-adrenoceptor agonist to ICS therapy recommended for patients with moderate or severe persistent asthma. The efficacy and safety of the combination of budesonide and formoterol delivered via dry ...
Known for Budesonide Pmdi | Severe Asthma | Formoterol Dpi | Efficacy Safety
KOL-Index: 21229 . IMPORTANCE: Extremely preterm infants contribute disproportionately to neonatal morbidity and mortality. OBJECTIVE: To review 20-year trends in maternal/neonatal care, complications, and mortality among extremely preterm infants born at Neonatal Research Network centers. DESIGN, SETTING, PARTICIPANTS: Prospective registry of 34,636 infants, 22 to 28 weeks' gestation, birth weight of 401 to ...
Known for Infants Gestational Age | Extremely Preterm | Morbidities Survival | Premature Infant
KOL-Index: 18902 . Importance: Adolescents and young adults with type 1 diabetes exhibit the worst glycemic control among individuals with type 1 diabetes across the lifespan. Although continuous glucose monitoring (CGM) has been shown to improve glycemic control in adults, its benefit in adolescents and young adults has not been demonstrated. Objective: To determine the effect of CGM on glycemic control in ...
Known for Glycemic Control | Glucose Monitoring | Type 1 Diabetes | Adolescents Young Adults
KOL-Index: 18816 . Germline intragenic mutations in PTEN are associated with 80% of patients with Cowden syndrome (CS) and 60% of patients with Bannayan-Riley-Ruvalcaba syndrome (BRRS). The underlying genetic causes remain to be determined in a considerable proportion of classic CS and BRRS without a polymerase chain reaction (PCR)-detectable PTEN mutation. We hypothesized that gross gene deletions and ...
Known for Pten Promoter | Patients Brrs | Ruvalcaba Syndrome | Genetic Protein
KOL-Index: 18404 . Importance: Hypothermia initiated at less than 6 hours after birth reduces death or disability for infants with hypoxic-ischemic encephalopathy at 36 weeks' or later gestation. To our knowledge, hypothermia trials have not been performed in infants presenting after 6 hours. Objective: To estimate the probability that hypothermia initiated at 6 to 24 hours after birth reduces the risk of ...
Known for 6 Hours | Ischemic Encephalopathy | Death Disability | Induced Hypoxiaischemia
KOL-Index: 18401 . OBJECTIVE: The effect of lopinavir/ritonavir (LPV/r) administration on cytochrome P450 (CYP) enzyme activity was quantified using a phenotyping biomarker cocktail. Changes in CYP2C9, CYP2C19, CYP3A, CYP1A2, N-acetyltransferase-2 (NAT-2), and xanthine oxidase (XO) activities were evaluated using warfarin (WARF) + vitamin K, omeprazole (OMP), intravenous (IV) and oral (PO) midazolam (MDZ), ...
Known for Cytochrome P450 | Cyp2c9 Cyp2c19 | Cyp3a Activity | Drug Cocktail
KOL-Index: 17899 . BACKGROUND: Among patients with malignant brain tumors, infants and very young children have the worst prognosis and the most severe treatment-related neurotoxic effects. Therefore, in 1986, the Pediatric Oncology Group began a study in which postoperative chemotherapy was given in order to permit a delay in the delivery of radiation to the developing brain. METHODS: Children under 36 ...
Known for Postoperative Chemotherapy | Malignant Brain Tumors | Age Diagnosis | Patients Radiation Therapy
KOL-Index: 17816 . BACKGROUND: After accounting for known risk factors for CKD progression in children, clinical outcomes among children with CKD still vary substantially. Biomarkers of tubular injury (such as KIM-1), repair (such as YKL-40), or inflammation (such as MCP-1, suPAR, TNF receptor-1 [TNFR-1], and TNFR-2) may identify children with CKD at risk for GFR decline. METHODS: We investigated whether ...
Known for Plasma Biomarkers | Ckd Progression | Tubular Injury | Type Receptors
KOL-Index: 17758 . Prader-Willi syndrome (PWS), the most common genetic cause of marked obesity in humans, is usually due to a de novo paternally derived chromosome 15q11-q13 deletion or maternal disomy 15 [(uniparental disomy (UPD)]. Obesity is due to energy imbalance, but few studies have examined fat patterning and obesity-related factors in subjects with PWS (deletions and UPD) compared with subjects ...
Known for Obese Subjects | Insulin Resistance | Simple Obesity | Pws Upd
KOL-Index: 17495 . OBJECTIVES: A randomized, masked, controlled trial was conducted to assess effects of supplementing premature infant formulas with oils containing the long-chain polyunsaturated fatty acids, arachidonic acid (AA; 20:4 n6), and docosahexaenoic acid (DHA; 22:6 n3) on growth, visual acuity, and multiple indices of development. METHODS: Infants (N = 470) with birth weights 750 to 1800 g were ...
Known for Visual Acuity | Controlled Trial | Aa Dha | Infants Fed
KOL-Index: 17455 . BACKGROUND: Minimal data exist to describe health-related quality of life in children with end-stage renal disease (ESRD). STUDY DESIGN: Cross-sectional study. SETTING & PARTICIPANTS: 193 children aged 5 to 18 years with ESRD and 190 parents of children aged 2 to 18 years with ESRD at 4 pediatric nephrology centers across the United States. OUTCOMES & MEASUREMENTS: Generic and ...
Known for Children Esrd | Pediatric Quality | Generic Core Scales | Life Pedsql
KOL-Index: 17167 . Prader-Willi syndrome is a neurodevelopmental disorder that is characterized by infantile hypotonia, feeding difficulties, hypogonadism, mental deficiency, hyperphagia (leading to obesity in early childhood), learning problems, and behavioral difficulties. A paternal 15q11-q13 deletion is found in approximately 70% of patients with Prader-Willi syndrome, approximately 25% have uniparental ...
Known for Willi Syndrome | 4 Genes | Individuals Deletion | Uniparental Maternal Disomy
KOL-Index: 16817 . OBJECTIVE: To compare the relative safety and efficacy of Infasurf (calf lung surfactant extract; ONY, Inc, Amherst, NY, IND #27169) versus Survanta (Beractant, Ross Laboratories, Columbus, OH) in reducing the acute severity of respiratory distress syndrome (RDS) when given at birth and to infants with established RDS. DESIGN: A prospective, randomized, double-blind, multicenter clinical ...
Known for Respiratory Distress Syndrome | Infants Infasurf | Lung Surfactant | Airway Pressure
KOL-Index: 16753 . IMPORTANCE: Previous studies assessing the effect of metformin on glycemic control in adolescents with type 1 diabetes have produced inconclusive results. OBJECTIVE: To assess the efficacy and safety of metformin as an adjunct to insulin in treating overweight adolescents with type 1 diabetes. DESIGN, SETTING, AND PARTICIPANTS: Multicenter (26 pediatric endocrinology clinics), ...
Known for Glycemic Control | Type 1 Diabetes | Participants Metformin | Placebo Difference

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