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  • From The University Of Minnesota Department Of Ped

From the University of Minnesota Department of Ped: Influence Statistics

From the University of Minnesota: Expert Impact

Concepts for which From the University of Minnesota has direct influence: Pediatric patients , Histiocytic disorders , Day patients , Solid tumors , Younger patients , Lymphoblastic leukemia , Epilepsy surgery .

From the University of Minnesota: KOL impact

Concepts related to the work of other authors for which for which From the University of Minnesota has influence: Lymphoblastic leukemia , Minimal residual disease , Pediatric patients , Cystic fibrosis , Acute myeloid , Childhood cancer , Central nervous .

KOL Resume for From the University of Minnesota Department of Ped


Prominent publications by From the University of Minnesota Department of Ped

KOL-Index: 18451 . BACKGROUND: We sought to improve outcome in patients with childhood acute myeloid leukaemia (AML) by applying risk-directed therapy that was based on genetic abnormalities of the leukaemic cells and measurements of minimal residual disease (MRD) done by flow cytometry during treatment. METHODS: From Oct 13, 2002, to June 19, 2008, 232 patients with de-novo AML (n=206), therapy-related or ...
Known for Monoclonal Antibodies | Newborn Leukemia | Induction Mrd | Childhood Acute
KOL-Index: 17035 . IMPORTANCE: Children born prematurely who develop retinopathy of prematurity (ROP) often develop myopia, and those who require laser treatment may develop very high myopia, which has considerable clinical consequences. OBJECTIVE: To report refractive outcomes in preterm infants who developed ROP in zone I or zone II posterior as stage 3+ ROP or aggressive posterior ROP (APROP). DESIGN, ...
Known for Laser Treatment | Refractive Outcomes | Intravitreal Bevacizumab | Eyes Received
KOL-Index: 15894 . BACKGROUND: Treatment of venous thromboembolism in children is based on data obtained in adults with little direct documentation of its efficacy and safety in children. The aim of our study was to compare the efficacy and safety of rivaroxaban versus standard anticoagulants in children with venous thromboembolism. METHODS: In a multicentre, parallel-group, open-label, randomised study, ...
Known for Venous Thromboembolism | Standard Anticoagulants | Safety Rivaroxaban | 3 Months
KOL-Index: 14634 . PURPOSE: To assess the toxicity, pharmacokinetics, and pharmacodynamics of multikinase inhibitor sorafenib in combination with clofarabine and cytarabine in children with relapsed/refractory leukemia. PATIENTS AND METHODS: Twelve patients with acute leukemia (11 with acute myeloid leukemia [AML]) received sorafenib on days 1 to 7 and then concurrently with cytarabine (1 g/m(2)) and ...
Known for Sorafenib Patients | Clofarabine Cytarabine | Refractory Leukemia | Complete Remission
KOL-Index: 14077 . Nonfermenting bacteria are ubiquitous environmental opportunists that cause infections in humans, especially compromised patients. Due to their limited biochemical reactivity and different morphotypes, misidentification by classical phenotypic means occurs frequently. Therefore, we evaluated the use of matrix-assisted laser desorption ionization-time-of-flight mass spectrometry (MALDI-TOF ...
Known for Nonfermenting Bacteria | 16s Rrna | Gene Sequencing | Species Identification
KOL-Index: 13645 . Childhood cancer survivors are at risk for development of subsequent neoplasms of the CNS. Better understanding of the rates, risk factors, and outcomes of subsequent neoplasms of the CNS among survivors of childhood cancer could lead to more informed screening guidelines. Two investigators independently did a systematic search of Medline and Embase (from January, 1966, through March, ...
Known for Subsequent Neoplasms | Childhood Cancer | Survivors Risk | Cranial Radiation
KOL-Index: 13622 . OBJECTIVE: To examine the effect of zinc sulfate supplementation on the concentrations of serum zinc and serum cholesterol in hemodialysis (HD) patients. SETTING: Outpatient dialysis center in a large metropolitan city. DESIGN: Randomized, double-blind, before-after trial. PATIENTS: Twenty-eight maintenance HD patients were selected. Twenty (15 women and 5 men) completed the study. ...
Known for Serum Zinc | Hemodialysis Patients | Cholesterol Concentrations | Energy Intake
KOL-Index: 13592 . Importance: Iron-deficiency anemia (IDA) affects millions of persons worldwide, and is associated with impaired neurodevelopment in infants and children. Ferrous sulfate is the most commonly prescribed oral iron despite iron polysaccharide complex possibly being better tolerated. Objective: To compare the effect of ferrous sulfate with iron polysaccharide complex on hemoglobin ...
Known for Ferrous Sulfate | Clinical Trial | Young Children | 12 Weeks
KOL-Index: 13529 . BACKGROUND & AIMS: The inflammatory bowel diseases (IBD) ulcerative colitis (UC) and Crohn's disease (CD) cause significant morbidity and are increasing in prevalence among all populations, including African Americans. More than 200 susceptibility loci have been identified in populations of predominantly European ancestry, but few loci have been associated with IBD in other ...
Known for African Americans | Inflammatory Bowel | Genome Wide | European Ancestry
KOL-Index: 13514 . Although aberrant Notch activation contributes to leukemogenesis in T cells, its role in acute myelogenous leukemia (AML) remains unclear. Here, we report that human AML samples have robust expression of Notch receptors; however, Notch receptor activation and expression of downstream Notch targets are remarkably low, suggesting that Notch is present but not constitutively activated in ...
Known for Notch Activation | Acute Mice Mice | Messenger Rna | Human Aml
KOL-Index: 13412 . OBJECTIVE: During the 2 decades in which effective antiviral therapies have been available for neonatal herpes simplex virus (HSV) disease, changes have been documented not only in the outcomes of infected infants, but also in the natural history of the disease itself. Numerous studies previously have reported that early institution of antiviral therapy is beneficial to the outcome of the ...
Known for Antiviral Therapy | Newborn Infant | Cns Disease | Human Herpesvirus
KOL-Index: 13308 . Importance: Clinical evidence supports effectiveness of cannabidiol for treatment-resistant seizures in Dravet syndrome, but this trial is the first to evaluate the 10-mg/kg/d dose. Objective: To evaluate the efficacy and safety of a pharmaceutical formulation of cannabidiol, 10 and 20 mg/kg/d, vs placebo for adjunctive treatment of convulsive seizures in patients with Dravet ...
Known for Dravet Syndrome | Seizure Frequency | Cannabidiol Placebo | Percentage Reduction
KOL-Index: 12883 . Gene expression profiling of 207 uniformly treated children with high-risk B-progenitor acute lymphoblastic leukemia revealed 29 of 207 cases (14%) with markedly elevated expression of CRLF2 (cytokine receptor-like factor 2). Each of the 29 cases harbored a genomic rearrangement of CRLF2: 18 of 29 (62%) had a translocation of the immunoglobulin heavy chain gene IGH@ on 14q32 to CRLF2 in ...
Known for Poor Outcome | Janus Kinase | Crlf2 Rearrangements | Lymphoblastic Leukemia
KOL-Index: 12693 . OBJECTIVE: The objective of this investigation was to establish the safety of high-dose (HD) acyclovir for the treatment of neonatal herpes simplex virus (HSV) disease. In addition, an estimate of therapeutic efficacy was sought, both with respect to mortality and to morbidity. Virologic efficacy of HD acyclovir was also assessed. PARTICIPANTS: Infants who were
Known for Intravenous Acyclovir | Hsv Disease | Neonatal Herpes | Newborn Infusions
KOL-Index: 12587 . PURPOSE: Imatinib mesylate is a targeted agent that may be used against Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL), one of the highest risk pediatric ALL groups. PATIENTS AND METHODS: We evaluated whether imatinib (340 mg/m(2)/d) with an intensive chemotherapy regimen improved outcome in children ages 1 to 21 years with Ph+ ALL (N = 92) and compared ...
Known for Chemotherapy Imatinib | Lymphoblastic Leukemia | Outcome Children | Positive Acute

Key People For Pediatric Patients

Top KOLs in the world
Ching‐Hong ChingHon
acute lymphoblastic leukemia cell lymphoblastic minimal residual disease
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observational studies consort statement randomised trials
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stem cell bone marrow pediatric patients
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pediatric patients cardiopulmonary bypass cardiac surgery
Jeffrey S Hyams
ulcerative colitis inflammatory bowel disease pediatric patients
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consort statement reporting guidelines randomized controlled trials